CN102641307B - Ganoderma lucidum granule and preparation method thereof - Google Patents
Ganoderma lucidum granule and preparation method thereof Download PDFInfo
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- CN102641307B CN102641307B CN201210154560.3A CN201210154560A CN102641307B CN 102641307 B CN102641307 B CN 102641307B CN 201210154560 A CN201210154560 A CN 201210154560A CN 102641307 B CN102641307 B CN 102641307B
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Abstract
The invention discloses a ganoderma lucidum granule and a preparation method thereof, and belongs to the field of ganoderma lucidum processing. The preparation method comprises the steps of grinding residues after alcohol extraction of a ganoderma lucidum fruit body, adding cellulase, belta-glucanase and protease for enzymolysis, heating for enzyme inactivation and concentration to obtain paste, adding an auxiliary material and a wetting agent in the paste, uniformly mixing, and then granulating, drying and finishing, thus obtaining the ganoderma lucidum granule. Cellulase, belta-glucanase and protease are utilized for enzymolysis, the problem of low utilization rate of ganoderma lucidum in the traditional technology is solved and the utilization rate of ganoderma lucidum is improved remarkably; and through enzymolysis of different enzymes, ingredients in the ganoderma lucidum, which cannot be easily absorbed by human bodies, become products which can be easily absorbed by human bodies, the releasing of active ingredients and the product quality are improved, therefore the ganoderma lucidum granule and the preparation method therefore have remarkable economical and social benefits.
Description
Technical field
The invention belongs to Ganoderma manufacture field, more specifically relate to a kind of glossy ganoderma particle and preparation method thereof.
Background technology
Ganoderma is just considered to lucky, rich and honour, fine, long-lived symbol since ancient times, has the title of " Herba mesonae chinensis ", " Ganoderma ", and a chinese tradition medical science for a long time direct-view Ganoderma is strengthening by means of tonics, consolidates the precious Chinese herbal medicine of righting, life lengthening.In China the most ancient existing Chinese medicine ancient books and records < < Sheng Nong's herbal classic > >, record 365 kinds of Chinese medicines, be divided into upper, middle and lower three products, in 120 kinds of top grade Chinese medicines, Ganoderma is arranged higher than Radix Ginseng, for medicine-feeding, and according to the form of Ganoderma class and color, Ganoderma is divided into six sesames, think Ganoderma " pacify smart soul, increase wisdom; the beneficial motive; hard muscles and bones, good color, food is made light of one's life by commiting suicide not oldly for a long time, and angle prolongs life ".Pass in > > and say that Ganoderma is " medicine of go up very much " in < < Chinese force, " and eat it, the day after tomorrow and always ".In the < < Compendium of Materia Medica > > that the famous medical scholar's Li Shizhen (1518-1593 A.D.) of the Ming Dynasty is write, record: " Ganoderma bitter in the mouth, flat, nontoxic, the benefit motive, invigorate blood circulation, enter heart hyperemia, help the heart to fill arteries and veins, calm the nerves, lung benefiting gas, tonifying liver gas, invigorating middle warmer, increase wisdom, good color, profit joint, hard muscles and bones ... " now, Ganoderma was formally recorded by < < Pharmacopoeia of People's Republic of China > > in 2000 as medicine, it is again the new resource food of health ministry approval simultaneously, have no side effect, can medicine-food two-purpose.< < U.S. medical herbs pharmacopeia is also recorded Ganoderma with treatment summary (American Herbal Pharmacopoeia and Therapeutic Compendium) > >.
Summary of the invention
The object of the invention is to a kind of glossy ganoderma particle and preparation method thereof, utilize cellulase, 1,4 beta-glucanase and protease hydrolyzed, solved because of the low problem of traditional handicraft Ganoderma utilization rate, make the utilization of Ganoderma be significantly improved, and the zymolysis through different enzymes, the product that becomes human body easily to absorb the composition enzymolysis that is difficult in Ganoderma being absorbed by the body, improves when effective ingredient discharges and has also improved product quality, has significant economic and social benefit.
For achieving the above object, the present invention adopts following technical scheme:
A kind of preparation method of glossy ganoderma particle, the defective material of Ganoderma sporophore after alcohol extraction is through pulverizing, add cellulase, 1,4 beta-glucanase and protease to carry out enzymolysis, through intensification enzyme denaturing and concentrated, the paste obtaining, add adjuvant and wetting agent, mix homogeneously, through granulating, dry, granulate, obtains described glossy ganoderma particle.
The defective material of Ganoderma sporophore after alcohol extraction is through pulverizing, and fineness is at 60-120 order; Add cellulase, 1,4 beta-glucanase and protease to carry out enzymolysis, Degree of Enzymatic Hydrolysis >=90%.
The parts by weight of enzymolysis enzyme used are: 25～75 parts of cellulase, 25～75 parts of 1,4 beta-glucanases, proteinase-10 .1～45 part; The proportion that enzyme accounts for acetic acid-sodium acetate buffer solution is 0.03～1.0 ﹪; Hydrolysis temperature is 25～50 ℃, and enzymolysis time is 0.5～10 hour, and mixing speed is 20～120rpm.
Enzyme-removal temperature is 90～100 ℃, and the enzyme denaturing time is 20～30min.
The adjuvant adding is glossy ganoderma ultra-fine powder, and addition is 0.5-5 times of paste quality.
The wetting agent adding is high concentration ethanol solution, and concentration is more than 95%, and addition is 15～65% of paste quality.
Paste, adjuvant and wetting agent are put into blender and stir 30-150 minute, temperature is controlled at 20-60 ℃, makes its mix homogeneously, makes ointment; Through mesh screen, granulate, fineness of the particles is 10-60 order.
Baking temperature is 30-70 ℃, and drying time, 3-18h, controlled moisture to 2% following for spending; Through 65 mesh sieve granulate, space temperature is controlled as 18-26 ℃, and humidity is 20-50%.
The glossy ganoderma particle that a kind of preparation method as above makes.
Beneficial effect of the present invention:
(1) to adopt cellulase, 1,4 beta-glucanase, protease mixed enzyme be to come enzymolysis through the Ganoderma sporophore residue defective material of alcohol extraction in the present invention, makes the utilization rate of Ganoderma raw material be significantly improved, and improved economic benefit.
(2) by cellulase, 1,4 beta-glucanase, protease mixed enzyme, be that enzymolysis makes the release of the effective ingredient in Ganoderma more thorough, the product of enzymolysis is more easily absorbed and utilized by the body, and has strengthened the quality of product.
(3) cellulose is difficult for directly absorbed by the bodyly, uses cellulase degradation cellulose, the effective ingredient in cellulose is discharged fully, and be easier to the absorption of human body.
(4) taking convenience of granule, in routine work, also can improve immunity and resisting fatigue during study, and owing to being dissolved in aqueous solution, large with the contact area of human body, absorb fast, effective rapid, convenient, quick.
(5) patient that can only eat slop for some also can improve the immunity of self by edible glossy ganoderma granule, accelerates resume speed, has improved the health care of product, has expanded the colony of consumption.
The specific embodiment
In glossy ganoderma particle, the addition of adjuvant is major ingredient 0.5～5 times.
The machining process route of glossy ganoderma particle is: Ganoderma sporophore is enzymolysis → concentrate drying → paste Ganoderma vigor composition → add adjuvant and as high concentration ethanol → mix homogeneously → granulations of the sieving → granulate that be dried → sieves → finished product examination of wetting agent through alcohol extraction remaining defective material → cellulase, 1,4 beta-glucanase, protease mixed enzyme.
Procedure of processing comprises: choose the remaining defective material of Ganoderma sporophore through alcohol extraction, fineness is 60～120 orders, with cellulase, 1,4 beta-glucanase, protease mixed enzyme is enzymolysis, Degree of Enzymatic Hydrolysis >=90%, the product of enzymolysis process intensification enzyme denaturing and filtration under diminished pressure, pressure is-0.03～-0.10Mpa, concentrated through 70～100 ℃, concentration time is 1～5 hour, be concentrated into 1 ∕ 3～1 ∕ 10, obtaining the product of paste enzymolysis product enzymolysis and adjuvant and wetting agent puts into blender and stirs, mixing time is 30～150 minutes, make its mix homogeneously, through mesh screen, granulate, fineness of the particles is 10～60 orders.Then, through super-dry, baking temperature is 30～70 ℃, drying time 3～18h, dry granule is crossed sieve (65 order) granulate again No. four, obtains glossy ganoderma particle.
The remarkable advantage of this product is: cellulose can not be directly absorbed by the body, by cellulase, 1,4 beta-glucanase, protease mixed enzyme, is enzymolysis, and the effective ingredient in cellulose is discharged fully, and is easier to the absorption of human body.Owing to being dissolved in aqueous solution, large with the contact area of human body, absorb fast, effective rapid.The patient that can only eat slop for some also can improve the immunity of self by edible glossy ganoderma granule, accelerates resume speed, has improved the health care of product, has expanded the colony of consumption.
Be below several embodiments of the present invention, further illustrate the present invention, but the present invention is not limited only to this.
embodiment 1
In glossy ganoderma particle, the addition of adjuvant is major ingredient 0.5 times.
The machining process route of glossy ganoderma particle is: Ganoderma sporophore is enzymolysis → concentrate drying → paste Ganoderma vigor composition → add adjuvant and as high concentration ethanol → mix homogeneously → granulations of the sieving → granulate that be dried → sieves → finished product examination of wetting agent through alcohol extraction remaining defective material → cellulase, 1,4 beta-glucanase, protease mixed enzyme.
Procedure of processing comprises: choose the residue defective material through the Ganoderma sporophore of alcohol extraction, fineness is 60 orders, by cellulase, 1,4 beta-glucanase, protease mixed enzyme, it is enzymolysis, Degree of Enzymatic Hydrolysis >=90%, the product of enzymolysis process intensification enzyme denaturing and filtration under diminished pressure, pressure is-0.03Mpa, concentrated through 70 ℃, concentration time is 1 hour, is concentrated into 1 ∕ 3, and the product of enzymolysis and adjuvant and wetting agent are put into blender and stirred, mixing time is 30 minutes, make its mix homogeneously, through mesh screen, granulate, fineness of the particles is 10 orders.Then, through super-dry, baking temperature is 30 ℃, drying time 3h, dry granule is crossed sieve (65 order) granulate again No. four, obtains glossy ganoderma particle.
embodiment 2
In glossy ganoderma particle, the addition of adjuvant is major ingredient 3.5 times.
The machining process route of glossy ganoderma particle is: Ganoderma sporophore is enzymolysis → concentrate drying → paste Ganoderma vigor composition → add adjuvant and as high concentration ethanol → mix homogeneously → granulations of the sieving → granulate that be dried → sieves → finished product examination of wetting agent through alcohol extraction remaining defective material → cellulase, 1,4 beta-glucanase, protease mixed enzyme.
Procedure of processing comprises: choose the residue defective material through the Ganoderma sporophore of alcohol extraction, fineness is 100 orders, by cellulase, 1,4 beta-glucanase, protease mixed enzyme, it is enzymolysis, Degree of Enzymatic Hydrolysis >=90%, the product of enzymolysis process intensification enzyme denaturing and filtration under diminished pressure, pressure is-0.06Mpa, concentrated through 80 ℃, concentration time is 35 hours, is concentrated into 1 ∕ 7, and the product of enzymolysis and adjuvant and wetting agent are put into blender and stirred, mixing time is 90 minutes, make its mix homogeneously, through mesh screen, granulate, fineness of the particles is 40 orders.Then, through super-dry, baking temperature is 50 ℃, drying time 9h, dry granule is crossed sieve (65 order) granulate again No. four, obtains glossy ganoderma particle.
embodiment 3
In glossy ganoderma particle, the addition of adjuvant is major ingredient 5 times.
The machining process route of glossy ganoderma particle is: Ganoderma sporophore is enzymolysis → ointment Ganoderma vigor composition → add adjuvant and as high concentration ethanol → mix homogeneously → granulations of the sieving → granulate that be dried → sieves → finished product examination of wetting agent through alcohol extraction remaining defective material → cellulase, 1,4 beta-glucanase, protease mixed enzyme.
Procedure of processing comprises: choose through the remaining Ganoderma sporophore defective material of alcohol extraction, fineness is 120 orders, by cellulase, 1,4 beta-glucanase, protease mixed enzyme, it is enzymolysis, Degree of Enzymatic Hydrolysis >=90%, the product of enzymolysis process intensification enzyme denaturing and filtration under diminished pressure, pressure is-0.10Mpa, concentrated through 100 ℃, concentration time is 5 hours, is concentrated into 1 ∕ 10, and the product of enzymolysis and adjuvant and wetting agent are put into blender and stirred, mixing time is 150 minutes, make its mix homogeneously, through mesh screen, granulate, fineness of the particles is 60 orders.Then, through super-dry, baking temperature is 70 ℃, drying time 18h, dry granule is crossed sieve (65 order) granulate again No. four, obtains glossy ganoderma particle.
The foregoing is only preferred embodiment of the present invention, all equalizations of doing according to the present patent application the scope of the claims change and modify, and all should belong to covering scope of the present invention.
Claims (1)
1. a glossy ganoderma particle, it is characterized in that: the defective material of Ganoderma sporophore after alcohol extraction is through pulverizing, add cellulase, 1,4 beta-glucanase and protease to carry out enzymolysis, through intensification enzyme denaturing and concentrated, the paste obtaining, add adjuvant and wetting agent, mix homogeneously, through granulating, dry, granulate, obtains described glossy ganoderma particle;
The defective material of Ganoderma sporophore after alcohol extraction is through pulverizing, and fineness is at 60-120 order; Add cellulase, 1,4 beta-glucanase and protease to carry out enzymolysis, Degree of Enzymatic Hydrolysis >=90%;
The parts by weight of enzymolysis enzyme used are: 25～75 parts of cellulase, 25～75 parts of 1,4 beta-glucanases, proteinase-10 .1～45 part; The proportion that enzyme accounts for acetic acid-sodium acetate buffer solution is 0.03～1.0%; Hydrolysis temperature is 25～50 ℃, and enzymolysis time is 0.5～10 hour, and mixing speed is 20～120rpm;
Enzyme-removal temperature is 90～100 ℃, and the enzyme denaturing time is 20～30min;
The adjuvant adding is glossy ganoderma ultra-fine powder, and addition is 0.5-5 times of paste quality;
The wetting agent adding is high concentration ethanol solution, and concentration is more than 95%, and addition is 15～65% of paste quality;
Paste, adjuvant and wetting agent are put into blender and stir 30-150 minute, temperature is controlled at 20-60 ℃, makes its mix homogeneously, makes ointment; Through mesh screen, granulate, fineness of the particles is 10-60 order;
Baking temperature is 30-70 ℃, and drying time, 3-18h, controlled moisture to 2% following for spending; Through 65 mesh sieve granulate, space temperature is controlled as 18-26 ℃, and humidity is 20-50%.
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| CN105995966A (en) * | 2016-06-20 | 2016-10-12 | 张勇 | Preparation method of enzymolysis ganoderma lucidum powder |
| CN113678921A (en) * | 2021-08-27 | 2021-11-23 | 武平县营林公司 | Superfine grinding enzymolysis production process of purple lucid ganoderma instant tea |
Citations (5)
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| CN1559305A (en) * | 2004-02-20 | 2005-01-05 | 付茂康 | Glossy ganoderma beverage, and its prepn. method |
| CN1569903A (en) * | 2004-04-28 | 2005-01-26 | 中国食品发酵工业研究院 | Enzymolytic preparation method for glossy ganoderma amylose |
| CN101077500A (en) * | 2007-06-20 | 2007-11-28 | 上海拜森生物技术有限公司 | Processing method for biological pharmacy waste residue |
| CN101190241A (en) * | 2006-11-28 | 2008-06-04 | 杨荣庆 | Ganoderrma tsugae extracting technique and preparations thereof |
| CN101530436A (en) * | 2009-04-20 | 2009-09-16 | 浙江省林业科学研究院 | Method of effectively extracting ganoderma triterpenoids and ganoderan from mythic fungus germ entity |
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Patent Citations (5)
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|---|---|---|---|---|
| CN1559305A (en) * | 2004-02-20 | 2005-01-05 | 付茂康 | Glossy ganoderma beverage, and its prepn. method |
| CN1569903A (en) * | 2004-04-28 | 2005-01-26 | 中国食品发酵工业研究院 | Enzymolytic preparation method for glossy ganoderma amylose |
| CN101190241A (en) * | 2006-11-28 | 2008-06-04 | 杨荣庆 | Ganoderrma tsugae extracting technique and preparations thereof |
| CN101077500A (en) * | 2007-06-20 | 2007-11-28 | 上海拜森生物技术有限公司 | Processing method for biological pharmacy waste residue |
| CN101530436A (en) * | 2009-04-20 | 2009-09-16 | 浙江省林业科学研究院 | Method of effectively extracting ganoderma triterpenoids and ganoderan from mythic fungus germ entity |
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