CN102636469B - 荧光读取器 - Google Patents

荧光读取器 Download PDF

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Publication number
CN102636469B
CN102636469B CN201210123087.2A CN201210123087A CN102636469B CN 102636469 B CN102636469 B CN 102636469B CN 201210123087 A CN201210123087 A CN 201210123087A CN 102636469 B CN102636469 B CN 102636469B
Authority
CN
China
Prior art keywords
substrate
fluorescence
light
fluorescence reader
angle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201210123087.2A
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English (en)
Chinese (zh)
Other versions
CN102636469A (zh
Inventor
托马斯·林斯特龙
伊布·曼德尔-哈特维格
奥韦·奥曼
约翰·巴克伦
肯尼特·维尔赫尔姆森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Remsen International Assets LLC
J&j Jsc
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN102636469A publication Critical patent/CN102636469A/zh
Application granted granted Critical
Publication of CN102636469B publication Critical patent/CN102636469B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6465—Angular discrimination

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN201210123087.2A 2006-03-22 2007-03-21 荧光读取器 Expired - Fee Related CN102636469B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0600642A SE529711C2 (sv) 2006-03-22 2006-03-22 Fluorescensläsare
SE0600642-3 2006-03-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2007800096888A Division CN101405594B (zh) 2006-03-22 2007-03-21 荧光读取器

Publications (2)

Publication Number Publication Date
CN102636469A CN102636469A (zh) 2012-08-15
CN102636469B true CN102636469B (zh) 2016-07-06

Family

ID=38522714

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201210123087.2A Expired - Fee Related CN102636469B (zh) 2006-03-22 2007-03-21 荧光读取器
CN2007800096888A Expired - Fee Related CN101405594B (zh) 2006-03-22 2007-03-21 荧光读取器

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2007800096888A Expired - Fee Related CN101405594B (zh) 2006-03-22 2007-03-21 荧光读取器

Country Status (8)

Country Link
US (2) US8691153B2 (https=)
EP (1) EP1996922B1 (https=)
JP (1) JP5705432B2 (https=)
CN (2) CN102636469B (https=)
AU (1) AU2007227809B2 (https=)
BR (1) BRPI0709018A2 (https=)
SE (1) SE529711C2 (https=)
WO (1) WO2007108752A1 (https=)

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US20130060106A1 (en) * 2011-09-06 2013-03-07 Medtronic Minimed, Inc. Optical sensing systems and methods
EP2618149B1 (en) 2012-01-20 2016-07-27 Ortho-Clinical Diagnostics, Inc. Assay device having uniform flow around corners
CA2802260C (en) 2012-01-20 2021-03-30 Ortho-Clinical Diagnostics, Inc. Controlling fluid flow through an assay device
KR20130085994A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 다수의 시약 셀을 갖는 분석 장치
KR20130085992A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 제어가능한 샘플 크기를 갖는 분석 장치
WO2013109821A1 (en) 2012-01-20 2013-07-25 Ortho-Clinical Diagnostics, Inc. Assay device having multiplexing
ES2978909T3 (es) 2012-08-21 2024-09-23 Janssen Pharmaceutica Nv Anticuerpos contra haptenos de aripiprazol y uso de los mismos
JP6389177B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ．ベー． オランザピンハプテンに対する抗体及びその使用
EP3462173B1 (en) 2012-08-21 2021-03-31 Janssen Pharmaceutica NV Antibodies to risperidone and use thereof
ES2654413T3 (es) 2012-08-21 2018-02-13 Janssen Pharmaceutica, N.V. Anticuerpos a quetiapina y uso de los mismos
CN104736565B (zh) 2012-08-21 2019-03-12 詹森药业有限公司 利培酮半抗原的抗体及其用途
CA2882562C (en) 2012-08-21 2019-08-27 Eric Hryhorenko Antibodies to aripiprazole and use thereof
ES2652641T3 (es) 2012-08-21 2018-02-05 Janssen Pharmaceutica Nv Haptenos de aripiprazol y su uso en inmunoensayos
US9494608B2 (en) 2012-08-21 2016-11-15 Janssen Pharmaceutica Nv Antibodies to olanzapine and use thereof
CA2882490A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone and use thereof
ES2788716T3 (es) 2012-08-21 2020-10-22 Janssen Pharmaceutica Nv Anticuerpos para haptenos de quetiapina y uso de los mismos
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
JP6359263B2 (ja) 2012-11-15 2018-07-18 オーソ・クリニカル・ダイアグノスティックス・インコーポレーテッド 流れモニタリングに基づく、側方流動アッセイ装置の品質／プロセス制御
WO2014078679A1 (en) 2012-11-15 2014-05-22 Ortho-Clinical Diagnostics, Inc. Calibrating assays using reaction time
CA2841692C (en) 2013-02-12 2023-08-22 Zhong Ding Reagent zone deposition pattern
FI128503B (en) 2013-02-27 2020-06-30 Teknologian Tutkimuskeskus Vtt Oy Sample plate and assay procedure
EP2778679B1 (en) 2013-03-15 2017-09-27 Ortho-Clinical Diagnostics, Inc. Rotable disk-shaped fluid sample collection device
EP2777499B1 (en) 2013-03-15 2015-09-16 Ortho-Clinical Diagnostics Inc Rotatable fluid sample collection device
EP3077806B1 (en) 2013-12-06 2019-09-11 Ortho Clinical Diagnostics, Inc. Assay device having a wash port
US9903858B2 (en) 2014-07-23 2018-02-27 Ortho-Clinical Diagnostics, Inc. Multiplexing with single sample metering event to increase throughput
US10071373B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device having flow constrictions
US11033896B2 (en) 2014-08-08 2021-06-15 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device with filtration flow control
KR101621050B1 (ko) * 2014-10-23 2016-05-13 주식회사 이뮨메드 의료용 진단 키트의 형광리더기
WO2016187244A1 (en) 2015-05-19 2016-11-24 Ortho-Clinical Diagnostics, Inc. Method of improving liquid sample flow in assay device
EP3390455A1 (en) 2015-12-17 2018-10-24 Janssen Pharmaceutica NV Antibodies to quetiapine and use thereof
CN108431040B (zh) 2015-12-17 2022-07-26 詹森药业有限公司 利培酮的抗体及其用途
CN107242860B (zh) * 2017-07-25 2021-01-19 京东方科技集团股份有限公司 荧光分子层析成像系统及方法
EP3460456B1 (en) * 2017-09-20 2020-08-26 IMEC vzw A biosensor system for detecting supercritical angle fluorescent light
JP7106217B2 (ja) * 2018-08-22 2022-07-26 株式会社ディスコ ファセット領域の検出方法及び検出装置
CN113993455A (zh) * 2019-03-01 2022-01-28 维迪亚控股有限公司 光学元件或与光学元件有关的改进
EP3705875B1 (en) 2019-03-05 2022-11-30 IMEC vzw An apparatus and method for detecting photoluminescent light emitted from a sample

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CN1423842A (zh) * 1999-12-03 2003-06-11 美商克立光学公司 藉由内部及外部光学组件之使用而加强发光二极管中的光放出
CN1437015A (zh) * 2002-01-23 2003-08-20 株式会社日立国际电气 荧光体检测方法及荧光体检测装置
CN1551983A (zh) * 2002-06-06 2004-12-01 索尼株式会社 生物测定单元及用于生物测定的基板

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Publication number Priority date Publication date Assignee Title
US3593055A (en) * 1969-04-16 1971-07-13 Bell Telephone Labor Inc Electro-luminescent device
CN1328638A (zh) * 1998-08-26 2001-12-26 医药及科学传感器公司 基于光学的感测装置
CN1423842A (zh) * 1999-12-03 2003-06-11 美商克立光学公司 藉由内部及外部光学组件之使用而加强发光二极管中的光放出
CN1437015A (zh) * 2002-01-23 2003-08-20 株式会社日立国际电气 荧光体检测方法及荧光体检测装置
CN1551983A (zh) * 2002-06-06 2004-12-01 索尼株式会社 生物测定单元及用于生物测定的基板

Also Published As

Publication number Publication date
US20140212984A1 (en) 2014-07-31
EP1996922A4 (en) 2012-10-24
SE0600642L (sv) 2007-09-23
CN101405594B (zh) 2012-06-27
WO2007108752A1 (en) 2007-09-27
AU2007227809A1 (en) 2007-09-27
SE529711C2 (sv) 2007-11-06
JP5705432B2 (ja) 2015-04-22
AU2007227809B2 (en) 2012-10-04
CN101405594A (zh) 2009-04-08
US20070231883A1 (en) 2007-10-04
JP2009530637A (ja) 2009-08-27
US9279768B2 (en) 2016-03-08
US8691153B2 (en) 2014-04-08
BRPI0709018A2 (pt) 2011-06-21
EP1996922B1 (en) 2018-11-21
CN102636469A (zh) 2012-08-15
EP1996922A1 (en) 2008-12-03

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Effective date of registration: 20180716

Address after: Delaware

Patentee after: J Remsen international assets LLC

Address before: Solna, Sweden

Patentee before: J&J JSC

Effective date of registration: 20180716

Address after: Solna, Sweden

Patentee after: J&J JSC

Address before: Uppsala, Sweden

Patentee before: Amic AB

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Granted publication date: 20160706