CN102614422A - Traditional Chinese medical decoction for treatment of acute gouty arthritis - Google Patents
Traditional Chinese medical decoction for treatment of acute gouty arthritis Download PDFInfo
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- CN102614422A CN102614422A CN2012101089738A CN201210108973A CN102614422A CN 102614422 A CN102614422 A CN 102614422A CN 2012101089738 A CN2012101089738 A CN 2012101089738A CN 201210108973 A CN201210108973 A CN 201210108973A CN 102614422 A CN102614422 A CN 102614422A
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Abstract
The invention relates to the field of a drug formula, in particular to composite traditional Chinese medical decoction for treatment of acute gouty arthritis, which consists of angelica polyclada, radix angelicae pubescentis, radices sileris, fried rhizoma atractylodis, ligusticum wallichii, mulberry twig, asarum, Tuckahoe, pawpaw, jujube paste, angelica sinensis, cassia twig, raw licorice, radix clematidis, macrophylla, stephania terandra, semen coicis, rhizoma corydalis, prepared olibanum, prepared myrrh and cinnamon. The cost is low, the efficacy is high, no toxic or side effects can be caused, the decoction has anti-inflammatory and analgesic effects and functions of invigorating qi and blood, eliminating dampness and dredging channels, the total efficiency is 95 percent, the curing rate is 80 percent, the improvement rate is 15 percent, and the rate of ineffectiveness is 5 percent.
Description
Technical field:
The present invention relates to a kind of prescription field of medicine, is a kind of herbal mixture decoction that is used to treat the gouty acute arthritis specifically.
Background technology:
The gouty acute arthritis is first symptom of gout, normal midnight onset, the single joint of burst lower limb far-end is red, swollen, hot, bitterly and dysfunction, the patient has heating, blood leukocytes increases, erythrocyte sedimentation rate speeds, and accompanies symptoms such as hyperuricemia.Be because the inflammatory reaction that the urate crystal deposition causes.But urate crystal chemotactic leukocyte, thus in the synovial bursa of joint the position of urate deposition, leukocyte significantly increases.After the leukocytes phagocytic urate, chemokines such as release of leukotriene B4 and glycoprotein possibly be the important medium of gout inflammatory reaction rapidly; And mononuclear cell receives urate to stimulate back release interleukin-11 also possibly cause the gout inflammation and make it aggravation.Uric acid is the end-product of purine metabolism; The nucleic acid and the purine in other purine compounds and the food that are mainly decomposed by cellular metabolism decompose through the effect of enzyme; A hyperuricemia person only part develops into clinical gouty acute arthritis, and it changes, and cutter system is not bright really.Mainly be to use colchicine, NSAID and application glucocorticoid antiinflammatory in the treatment, but cure the symptoms, not the disease, and side effects of pharmaceutical drugs are big, brought great misery and spirit, economically burden to patient.For this reason, we use theory of Chinese medical science, gather 21 flavor Chinese herbal medicine and fry in shallow oil soup, for a kind of new method has been created in the treatment of gouty acute arthritis.
Summary of the invention:
The present invention is the deficiency that overcomes prior art, provides that a kind of cost is low, curative effect is high, has had no side effect, and has antiinflammatory, pain relieving, benefiting vital QI and blood, the Chinese medicine decoction of the treatment gouty acute arthritis of eliminating dampness and dredging channels function.
A kind of Chinese medicine decoction of treating the gouty acute arthritis is characterized in that being made up of the component of following materials of weight proportions medicine: Rhizoma Et Radix Notopterygii 7-7.5%, Radix Angelicae Pubescentis 4-5%, windproof 3-4%, Rhizoma Atractylodis (parched) 4-5%, Rhizoma Chuanxiong 4-4.5%, Ramulus Mori 13-14%, Herba Asari 1-2%, Poria 7-8%, Fructus Chaenomelis 4-5%, big Fructus Jujubae 5-6%, Radix Angelicae Sinensis 5-6%, Ramulus Cinnamomi 2-3%, Radix Glycyrrhizae 1-2%, Radix Clematidis 3-3.5%, Radix Gentianae Marcrophyllae 3-3.5%, Radix Stephaniae Tetrandrae 3-4%, Semen Coicis 13-15%, Rhizoma Corydalis 3-4%, Olibanum (processed) 2.5-3%, Myrrha (processed) 2.5-3%, Cortex Cinnamomi 1-1.5%.
Pharmacology analysis: Rhizoma Et Radix Notopterygii, acrid in the mouth, hardship, temperature are returned bladder, liver, kidney channel, expelling wind and removing dampness.Be used for arthrodynia of extremities, and have tangible analgesia and antiinflammatory action.Radix Angelicae Pubescentis, acrid in the mouth, hardship, tepor are gone into kidney, urinary bladder channel.Expelling wind and removing dampness, dispersing cold for relieving pain.Be used for anemofrigid-damp arthralgia, the heavy pain of waist knee joint can be eased pain, calm, antiinflammatory.Windproof, acrid in the mouth, sweet, tepor are returned bladder, liver, lung, spleen channel, relieving the exterior syndrome with drugs of pungent in flavor and warm in nature, removing damp and stopping pain.Be used for cold-damp property arthralgia, but the warming the meridian and activating blood circulation collateral dredging.Rhizoma Atractylodis (parched), acrid in the mouth, hardship, temperature are returned spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and removing dampness.Be used for inappetence due to the burnt dyspepsia, arthralgia, limbs are stranded heavy.Rhizoma Chuanxiong, acrid in the mouth, temperature are returned liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for various pains cards due to the stagnation of blood stasis, the joint cold type of pain.Ramulus Mori, mildly bitter flavor, flat is gone into Liver Channel.Expelling wind and removing dampness, the collateral dredging detumescence.Be used for articular instability, edema.Herba Asari, acrid in the mouth, temperature are gone into the heart, lung, kidney channel.Expelling cold and relieving exterior syndrome, wind-expelling pain-stopping.Be used for extremities joint pain, antiinflammatory and immunosuppressive action are arranged.Poria, sweet in the mouth, light, flat, GUIXIN, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, the invigorating middle warmer spleen invigorating.The swelling of harnessing the river is full, dysuria.Fructus Chaenomelis, sour in the mouth, temperature are returned liver, spleen channel.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, removing dampness to restore normal function of the stomach.Be used for arthrodynia of extremities, nausea and vomiting.Big Fructus Jujubae, sweet in the mouth, temperature are returned spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind relaxes the property of medicine.Be used for weakness of the spleen and stomach, irritability restricts the high violent and poison property of medicine.Radix Angelicae Sinensis, sweet in the mouth, suffering, temperature are returned liver, the heart, spleen channel.Promoting blood circulation and stopping pain is used for swelling and pain due to blood stasis, the arthralgia pain of the cold meridians that stagnate.Have antiinflammatory, analgesic effect.Ramulus Cinnamomi, acrid in the mouth, sweet, warm is gone into the heart, lung, urinary bladder channel.Promoting the flow of QI in the collateral by warming the meridian, supporing yang activating QI.Analgesia, sedation are arranged.Radix Glycyrrhizae, sweet in the mouth, flat is gone into the heart, lung, spleen, stomach warp.The QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.The effect of glucocorticoid appearance is arranged, Anhydroalkannin, spasmolytic.In compound recipe, use Radix Glycyrrhizae, to alleviate or to relax the bias and the toxicity of medicine.Radix Clematidis, acrid in the mouth, salty, warm is returned urinary bladder channel.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Be used for arthralgia, joint stuffiness.Radix Gentianae Marcrophyllae, is slightly cold at acrid in the mouth, hardship.Return stomach, liver, gallbladder meridian.Expelling wind and removing dampness, eliminating damp-heat.Be used for arthralgia, the passages through which vital energy circulates contraction is anxious, the effect that has the indirect stimulation 17-hydroxy-11-dehydrocorticosterone to increase.Radix Stephaniae Tetrandrae, acrid in the mouth, hardship, cold are gone into lung, spleen, urinary bladder channel.Expelling wind and removing dampness, inducing diuresis to remove edema, clearing away heat-damp and promoting diuresis.Be used for arthralgia.Semen Coicis, sweet in the mouth, light, cool is gone into spleen, stomach, large intestine, lung meridian.The spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment pain relieving.Be used for the humidity hysteresis meridians, arthralgia.Rhizoma Corydalis, acrid in the mouth, hardship, temperature are returned liver, spleen channel.Promoting blood circulation to remove obstruction in the collateral, promoting the circulation of QI to relieve pain.Be used for qi depression to blood stasis, stagnation of QI due to depression of the liver, all kinds of pain card.Olibanum (processed), acrid in the mouth, hardship, temperature.GUIXIN, liver, spleen channel.Promoting blood circulation and stopping pain, detumescence and promoting granulation.Be used for stagnation of QI and blood, all kinds of pain, pyogenic skin infection and carbuncle-abscess.Myrrha (processed), bitter in the mouth, flat, GUIXIN, liver, spleen channel.Promoting blood circulation and stopping pain, detumescence and promoting granulation.Be used for stagnation of blood stasis, pyogenic skin infection and carbuncle-abscess.Cortex Cinnamomi, acrid in the mouth, sweet, big heat are returned spleen, kidney, the heart, Liver Channel.Dispersing cold for relieving pain, warming the meridian and promoting blood circulation.Analgesia, calmness, refrigeration function are arranged.21 flavor Chinese medicines ingenious prescriptions reach the effect of mutual reinforcement between, the mutual-assistance, mutual restraint between two drugs between the medicine, curative effect of medication is strengthened, and improve the principal agent effect, and its toxic and side effects is alleviated or disappear.To reach benefiting vital QI and blood, eliminating dampness and dredging channels, analgesic effect, the specially good effect of treatment gouty acute arthritis.
Dosage form and usage: get above-mentioned side's medicine 300g, at room temperature 21 kinds of Chinese herbal medicine are added water to 900-1000ml, soaked 4 hours; After boiling, intense fire changes slow fire boiling 100-120 minute; Remove slag to such an extent that filtrate about 200ml, medicinal residues add water 300-400ml again, decoct 30-40 minute; Remove slag about filtrating 100ml, decoct medicine soup 300ml altogether twice.Every day, potion was oral at twice, and each (medicine) being taken before meal 150ml once a day, takes to clinical symptom disappearance seven days one courses of treatment, consolidates curative effect again and takes a course of treatment, generally uses three courses of treatment.
Clinical efficacy is summed up:
(1) physical data: accept patient's 40 examples altogether for medical treatment, male's 28 examples wherein, women's 12 examples; The oldest 78 years old, minimum 22 years old, 42 years old mean age; The elder of the course of disease 15 days, the shortest person 2 days, average 13 days.
(2) diagnostic criteria: more than the outbreak once of (1) acute arthritis, in 1 day, promptly reach the outbreak peak; (2) acute arthritis is confined to indivedual joints.Whole joint is kermesinus.First thumb joint swells and ache; (3) the scorching acute attack of one-sided midtarsal joints; (4) tophus is arranged; (5) hyperuricemia; (6) asymmetry arthralgia; (7) outbreak can stop voluntarily.All possess above-mentioned condition more than 3, and the person that can get rid of the secondary gout.
(3) efficacy assessment standard
Cure: subjective symptoms disappears, and redness and swelling of joints disappears.
Take a turn for the better: subjective symptoms disappears, and redness and swelling of joints alleviates.
Do not heal: the back state of an illness no change of taking medicine.
(4) therapeutic effect
Taking medicine 7 days is a course of treatment, and the lighter fully recovers for one course of treatment, and weight person 2-3 takes a turn for the better or fully recover the course of treatment.Total effective rate 95%, cure rate 80%, improvement rate 15%, invalid 5%.
The specific embodiment:
Below in conjunction with embodiment the present invention is further specified:
Embodiment 1: a kind of Chinese medicine decoction of treating the gouty acute arthritis, it is made up of the component of following weight (%) proportion raw material medicine: Rhizoma Et Radix Notopterygii 7.2, Radix Angelicae Pubescentis 4.6, windproof 3.4, Rhizoma Atractylodis (parched) 4.4, Rhizoma Chuanxiong 4.4, Ramulus Mori 13.8, Herba Asari 1.2, Poria 7.3, Fructus Chaenomelis 4.6, big Fructus Jujubae 5.8, Radix Angelicae Sinensis 5.1, Ramulus Cinnamomi 2.5, Radix Glycyrrhizae 1.2, Radix Clematidis 3.4, Radix Gentianae Marcrophyllae 3.3, Radix Stephaniae Tetrandrae 3.6, Semen Coicis 14.6, Rhizoma Corydalis 3.2, Olibanum (processed) 2.6, Myrrha (processed) 2.6, Cortex Cinnamomi 1.2.
Embodiment 2: a kind of Chinese medicine decoction of treating the gouty acute arthritis, it is made up of the component of following weight (%) proportion raw material medicine: Rhizoma Et Radix Notopterygii 7.4, Radix Angelicae Pubescentis 4.2, windproof 3.6, Rhizoma Atractylodis (parched) 4.8, Rhizoma Chuanxiong 4.3, Ramulus Mori 13.4, Herba Asari 1.5, Poria 7.8, Fructus Chaenomelis 4.3, big Fructus Jujubae 5.1, Radix Angelicae Sinensis 5.6, Ramulus Cinnamomi 2.8, Radix Glycyrrhizae 1.6, Radix Clematidis 3.3, Radix Gentianae Marcrophyllae 3.4, Radix Stephaniae Tetrandrae 3.2, Semen Coicis 13.2, Rhizoma Corydalis 3.6, Olibanum (processed) 2.8, Myrrha (processed) 2.7, Cortex Cinnamomi 1.4.
The Chinese medicine decoction of this kind treatment gouty acute arthritis is people and different due to illness; Only adjust Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, windproof, Rhizoma Atractylodis (parched), Rhizoma Chuanxiong, Ramulus Mori, Herba Asari, Poria, Fructus Chaenomelis, big Fructus Jujubae, Radix Angelicae Sinensis, Ramulus Cinnamomi, Radix Glycyrrhizae, Radix Clematidis, Radix Gentianae Marcrophyllae, Radix Stephaniae Tetrandrae, Semen Coicis, Rhizoma Corydalis, Olibanum (processed), Myrrha (processed), cinnamomic addition; Other operational approach and embodiment one or embodiment two are basic identical; Its content is as shown in the table, and unit of weight is gram.
Medicine soup embodiment (weight %)
| Embodiment | Example 11 | Example 13 | Example 16 |
| Rhizoma Et Radix Notopterygii | 7.1 | 7.3 | 7.5 |
| Radix Angelicae Pubescentis | 4.4 | 4.8. | 4.1 |
| Windproof | 3.3 | 3.1 | 3.7 |
| Rhizoma Atractylodis (parched) | 4.8 | 4.2 | 4.6 |
| Rhizoma Chuanxiong | 4.2 | 4.4 | 4.1 |
| Ramulus Mori | 13.1 | 13.5 | 13.6 |
| Herba Asari | 1.6 | 1.3 | 1.1 |
| Poria | 7.2 | 7.6 | 7.6 |
| Fructus Chaenomelis | 4.8 | 4.5 | 4.4 |
| Big Fructus Jujubae | 5.4 | 5.6 | 5.7 |
| Radix Angelicae Sinensis | 5.7 | 5.4 | 5.3 |
| Ramulus Cinnamomi | 2.6 | 2.3 | 2.7 |
| Radix Glycyrrhizae | 1.8 | 1.5 | 1.4 |
| Radix Clematidis | 3.1 | 3.2 | 3.3 |
| Radix Gentianae Marcrophyllae | 3.2 | 3.1 | 3.3 |
| Radix Stephaniae Tetrandrae | 3.8 | 3.7 | 3.5 |
| Semen Coicis | 13.4 | 14.0 | 14.1 |
| Rhizoma Corydalis | 3.7 | 3.5 | 3.4 |
| Olibanum (processed) | 2.7 | 2.9 | 2.8 |
| Myrrha (processed) | 2.8 | 3.0 | 2.6 |
| Cortex Cinnamomi | 1.3 | 1.1 | 1.2 |
| Add up to | 100 | 100 | 100 |
Model case:
Case 1: Lee, the woman, 40 years old, the peasant, go to a doctor in October, 2008.Right sufficient big toe swells and ache limitation of activity before being set forth in for 1 week.Have a medical check-up: right sufficient big toe is red and swollen, pale tongue, and the little Huang of tongue is greasy, moderate pulse.According to its symptom and sign, dialectical for cold-damp resistance network, give eliminating dampness and dredging channels.Take a course of treatment with our medicine, symptom obviously alleviates, and continues and obeys a course of treatment, and all diseases disappear and fully recover.
Case 2: Liu, the man, 25 years old, individuality, go to a doctor in June, 2007.Readme is red and swollen, the pain of right ankle and foot before 3 days, limitation of activity.From clothes " diclofenac potassium " treatment, clothes back poor effect is so come the court to go to a doctor.Have a medical check-up: right ankle local joint is red and swollen, pale tongue, and tongue is white, moderate pulse.Examine to cold-damp resistance network, give our medicine and take a course of treatment, all disease disappearances are fully recovered.
Claims (1)
1. a Chinese medicine decoction of treating the gouty acute arthritis is characterized in that being made up of the component of following materials of weight proportions medicine: Rhizoma Et Radix Notopterygii 7-7.5%, Radix Angelicae Pubescentis 4-5%, windproof 3-4%, Rhizoma Atractylodis (parched) 4-5%, Rhizoma Chuanxiong 4-4.5%, Ramulus Mori 13-14%, Herba Asari 1-2%, Poria 7-8%, Fructus Chaenomelis 4-5%, big Fructus Jujubae 5-6%, Radix Angelicae Sinensis 5-6%, Ramulus Cinnamomi 2-3%, Radix Glycyrrhizae 1-2%, Radix Clematidis 3-3.5%, Radix Gentianae Marcrophyllae 3-3.5%, Radix Stephaniae Tetrandrae 3-4%, Semen Coicis 13-15%, Rhizoma Corydalis 3-4%, Olibanum (processed) 2.5-3%, Myrrha (processed) 2.5-3%, Cortex Cinnamomi 1-1.5%.
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Cited By (9)
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| CN103141651A (en) * | 2013-02-24 | 2013-06-12 | 沈根林 | Traditional Chinese medicine sweetmeat sausage for dispelling wind damp |
| CN103385930A (en) * | 2012-05-07 | 2013-11-13 | 李建芳 | Quick-acting rheumatism powder |
| CN103655786A (en) * | 2014-01-08 | 2014-03-26 | 黄金标 | Traditional Chinese medicine composition for treating hyperuricemia and gout |
| CN103841154A (en) * | 2012-11-26 | 2014-06-04 | 腾讯科技（北京）有限公司 | Network media information publishing method, system and client |
| CN104491033A (en) * | 2014-12-10 | 2015-04-08 | 高振梅 | Traditional Chinese medicine composition for reducing muscular tension of paralytic patients |
| CN104998136A (en) * | 2015-07-21 | 2015-10-28 | 李建辉 | Neck and shoulder collateral activating paste and preparation method thereof |
| CN108236682A (en) * | 2016-12-24 | 2018-07-03 | 刘双 | The preparation method of gout rehabilitation paste |
| CN114732879A (en) * | 2022-04-14 | 2022-07-12 | 陈楚翁 | Medicine composition for gout and high uric acid and preparation method and application thereof |
| CN116036158A (en) * | 2022-09-09 | 2023-05-02 | 山西黄河中药有限公司 | Pharmaceutical composition for treating gouty arthritis and preparation method thereof |
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| CN103385930A (en) * | 2012-05-07 | 2013-11-13 | 李建芳 | Quick-acting rheumatism powder |
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| CN103841154A (en) * | 2012-11-26 | 2014-06-04 | 腾讯科技（北京）有限公司 | Network media information publishing method, system and client |
| CN103141651A (en) * | 2013-02-24 | 2013-06-12 | 沈根林 | Traditional Chinese medicine sweetmeat sausage for dispelling wind damp |
| CN103655786A (en) * | 2014-01-08 | 2014-03-26 | 黄金标 | Traditional Chinese medicine composition for treating hyperuricemia and gout |
| CN103655786B (en) * | 2014-01-08 | 2015-08-19 | 黄金标 | A kind of Chinese medicine composition for the treatment of hyperuricemia and gout |
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| CN104998136A (en) * | 2015-07-21 | 2015-10-28 | 李建辉 | Neck and shoulder collateral activating paste and preparation method thereof |
| CN108236682A (en) * | 2016-12-24 | 2018-07-03 | 刘双 | The preparation method of gout rehabilitation paste |
| CN114732879A (en) * | 2022-04-14 | 2022-07-12 | 陈楚翁 | Medicine composition for gout and high uric acid and preparation method and application thereof |
| CN114732879B (en) * | 2022-04-14 | 2023-09-01 | 陈楚翁 | Pharmaceutical composition for gout and uric acid elevation and preparation method and application thereof |
| CN116036158A (en) * | 2022-09-09 | 2023-05-02 | 山西黄河中药有限公司 | Pharmaceutical composition for treating gouty arthritis and preparation method thereof |
| CN116036158B (en) * | 2022-09-09 | 2023-10-13 | 山西黄河中药有限公司 | Pharmaceutical composition for treating gouty arthritis and preparation method thereof |
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