CN102614283A - Medicament for promoting postoperative gastrointestinal function recovery and application of medicament - Google Patents
Medicament for promoting postoperative gastrointestinal function recovery and application of medicament Download PDFInfo
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- CN102614283A CN102614283A CN2012100982881A CN201210098288A CN102614283A CN 102614283 A CN102614283 A CN 102614283A CN 2012100982881 A CN2012100982881 A CN 2012100982881A CN 201210098288 A CN201210098288 A CN 201210098288A CN 102614283 A CN102614283 A CN 102614283A
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Abstract
The invention provides a medicament for promoting postoperative gastrointestinal function recovery. The medicament is prepared from the following Chinese herbal medicines in part by weight: 5 to 15 parts of dried orange peel, 5 to 15 parts of costus root, 5 to 15 parts of officinal magnolia bark, 5 to 15 parts of tuckahoe, 5 to 15 parts of root of red-rooted salvia, 5 to 15 parts of rhubarb, 5 to 15 parts of Chinese angelica, 5 to 15 parts of green tangerine peel, 5 to 15 parts of ginger processed pinellia tuber, and 3 to 5.5 parts of senna leaf. The invention also provides application of the medicament in preparation of medicaments for promoting postoperative gastrointestinal function recovery. Compared with the prior art, the medicament has the advantages that the raw material components are reduced, and the treatment effect is equivalent, so that the cost is reduced, the economical burden of patients is lightened, and the medicament is easy and convenient to prepare; the medicament effectively treats the root causes of weak postoperative gastrointestinal functions, and has a remarkable curative effect; and the medicament is prepared from pure Chinese medicaments, so the medicament does not have toxic or side effect and is easily accepted by the patients.
Description
Technical field
The present invention relates to a kind of medicine and application thereof that promotes gastrointestinal function recovery, specifically, is to be the Chinese patent medicine of feedstock production with the Chinese herbal medicine.
Background technology
Malignant tumor of ovary accounts for 24%～56% of women's common cancer, in the female genital tract carcinoma, accounts for the 3rd.Operation is the main means of treatment ovarian cancer.The ovarian cancer operation is owing to will do pelvic cavity and the other lymph node dissection of ventral aorta; Operation wound has been not limited to pelvic cavity but must stimulation have been arranged to abdominal cavity and intestinal tube through the operation of abdomen; Gastrointestinal tract unavoidably is interfered even damages; Add the temporary transient inhibition of anaesthetic, postoperative the property crossed a gastrointestinal peristalsis disappearance occurs and the intestinal tube paralysis takes place, and the morning and evening of gastrointestinal function recovery is directly connected to the rehabilitation of patient with operation.Therefore, adopt Drug therapy,, promote gastrointestinal function to recover to be very necessary early to alleviate patient's postoperative abdominal distention symptom.
Generally believe at present; Abdominal operation operation, anesthesia and patient's primary disease, the medicine of treatment, postoperative water electrolysis acid base imbalance, postoperative pain, malnutrition, positive position etc. all can cause the nerve of intestinal wall endogenous locomotor activity to suppress, thereby cause the generation of the slow and enteroparalysis of restoration of gastrointestinal function.Traditional Chinese medical science viewpoint thinks, abdominal postoperative is because mistake department falls in gastrointestinal smoother, patient card marquis such as occur suffer from abdominal pain, expand, close, vomit, and operation causes the patient and consumes and hinder vigour, loses Tianjin blood and the deficiency of vital energy, anemia syndrome of blood stasis marquis occur, thereby increased the weight of the enteroparalysis degree.Theory of Chinese medical science also thinks, behind the abdominal surgery because of wound, lose blood, anaesthetize, QI-blood circulation is unable, the gastrointestinal function dereliction of duty, clear QI failing to ascend, turbid QI failing to descend hinders in middle Jiao, internal organs gas is difficult logical.
Chinese periodical " Jiangsu medicine ", the 36th the 20th phase of volume of October in 2010, " observation of curative effect of soup associating acupuncture of regulating the flow of vital energy " published to ovarian cancer operation back restoration of gastrointestinal function; Adopt following Therapeutic Method: salviamiltiorrhizabung, Radix Angelicae Sinensis, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Poria, Pericarpium Citri Reticulatae Viride, living army, each 10g of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Folium Sennae 6g decocte with water extracting juice 300ml, 100ml/ time; 3 times/d; Postoperative 24h begins to be injected and folder closes stomach tube 2h by stomach tube, stops the clothes of withdrawing the previous remark after the gastrointestinal decompression, obeys 5 doses altogether; 2 times/d of acupuncture point selection tsu san li, 5d has obtained good curative effect altogether.But the raw material type of this medicine is various; Receive the wide rare restriction in raw material source unavoidably, and, can bring heavy financial burden to the patient because some Chinese crude drug costs an arm and a leg; Thereby be not suitable for promoting the use of; Be necessary on this basis, to simplify, provide a kind of flavour of a drug number few, promote the effective medicine of malignant tumor of ovary gastrointestinal function recovery, but also do not appear in the newspapers about this type medicine at present.
Summary of the invention
The objective of the invention is provides a kind of medicine that promotes gastrointestinal function recovery to deficiency of the prior art.
One purpose more of the present invention is that a kind of purposes of said medicine is provided.
For realizing above-mentioned purpose, the technical scheme that the present invention takes is:
A kind of medicine that promotes gastrointestinal function recovery, it mainly is to be processed by following bulk drugs: Pericarpium Citri Reticulatae 5-15 part, Radix Aucklandiae 5-15 part, Cortex Magnoliae Officinalis 5-15 part, Poria 5-15 part, Radix Salviae Miltiorrhizae 5-15 part, Radix Et Rhizoma Rhei 5-15 part.
If described drug main is processed by following bulk drugs: Pericarpium Citri Reticulatae 8-12 part, Radix Aucklandiae 8-12 part, Cortex Magnoliae Officinalis 8-12 part, Poria 8-12 part, Radix Salviae Miltiorrhizae 8-12 part, Radix Et Rhizoma Rhei 8-12 part.
If described drug main is processed by following bulk drugs: 10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Cortex Magnoliae Officinalis, 10 parts in Poria, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Et Rhizoma Rhei.
Described medicine also comprises following bulk drugs: Radix Angelicae Sinensis 5-15 part, Pericarpium Citri Reticulatae Viride 5-15 part.
Described medicine also comprises following bulk drugs: Radix Angelicae Sinensis 8-12 part, Pericarpium Citri Reticulatae Viride 8-12 part.
Described medicine also comprises following bulk drugs: 10 parts of Radix Angelicae Sinensis, 10 parts on Pericarpium Citri Reticulatae Viride.
Described medicine also comprises following bulk drugs: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5-15 part, Folium Sennae 3-5.5 part.
Described medicine also comprises following bulk drugs: 10 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5 parts of Folium Sennae.
The medicament of described medicine is capsule, granule, tablet, oral liquid, mixture or syrup.
For realizing above-mentioned second purpose, the technical scheme that the present invention takes is:
The application of aforesaid medicine in the medicine of preparation promotion gastrointestinal function recovery.
The invention has the advantages that:
1, medicine material component of the present invention compared with prior art reduces to some extent, but therapeutic effect and prior art are suitable, thereby has reduced cost, has alleviated patient's financial burden, makes the preparation of medicine also easier simultaneously;
2, medicine of the present invention is to the weak etiology and pathogenesis of postoperative gastric intestinal function, gos deep into that it is basic, evident in efficacy;
3, medicine of the present invention is processed by pure Chinese medicine, has no side effect, and is easy to accepted by the patient.
The specific embodiment
Elaborate in the face of the specific embodiment provided by the invention down.
Embodiment 1 promotes the preparation () of the medicine one of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 15 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 2 promotes the preparation (two) of the medicine one of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 5 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 15 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 3 promotes the preparation (three) of the medicine one of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 5 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 15 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 4 promotes the preparation (four) of the medicine one of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 5 promotes the preparation (five) of the medicine one of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 6 promotes the preparation (six) of the medicine one of gastrointestinal function recovery
8 parts of Pericarpium Citri Reticulataes, 12 parts of the Radix Aucklandiae, 8 parts of Cortex Magnoliae Officinalis, 8 parts in Poria, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 7 promotes the preparation (seven) of the medicine one of gastrointestinal function recovery
12 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 12 parts of Cortex Magnoliae Officinalis, 12 parts in Poria, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 8 promotes the preparation (eight) of the medicine one of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 12 parts of Cortex Magnoliae Officinalis, 8 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 9 promotes the preparation (nine) of the medicine one of gastrointestinal function recovery
Old 5 parts, 5 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 12 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 10 promotes the preparation (ten) of the medicine one of gastrointestinal function recovery
10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Cortex Magnoliae Officinalis, 10 parts in Poria, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Et Rhizoma Rhei, conventional method decocts.
Embodiment 11 promotes the preparation () of the medicine two of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 15 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Angelicae Sinensis, 15 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 12 promotes the preparation (two) of the medicine two of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 5 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 15 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Et Rhizoma Rhei, 15 parts of Radix Angelicae Sinensis, 5 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 13 promotes the preparation (three) of the medicine two of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 5 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 15 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Et Rhizoma Rhei, 15 parts of Radix Angelicae Sinensis, 15 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 14 promotes the preparation (four) of the medicine two of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Angelicae Sinensis, 5 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 15 promotes the preparation (five) of the medicine two of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Angelicae Sinensis, 15 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 16 promotes the preparation (six) of the medicine two of gastrointestinal function recovery
8 parts of Pericarpium Citri Reticulataes, 12 parts of the Radix Aucklandiae, 8 parts of Cortex Magnoliae Officinalis, 8 parts in Poria, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Et Rhizoma Rhei, 8 parts of Radix Angelicae Sinensis, 12 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 17 promotes the preparation (seven) of the medicine two of gastrointestinal function recovery
12 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 12 parts of Cortex Magnoliae Officinalis, 12 parts in Poria, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Angelicae Sinensis, 8 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 18 promotes the preparation (eight) of the medicine two of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 12 parts of Cortex Magnoliae Officinalis, 8 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Angelicae Sinensis, 5 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 19 promotes the preparation (nine) of the medicine two of gastrointestinal function recovery
Old 5 parts, 5 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 12 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Et Rhizoma Rhei, 8 parts of Radix Angelicae Sinensis, 8 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 20 promotes the preparation (ten) of the medicine two of gastrointestinal function recovery
10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Cortex Magnoliae Officinalis, 10 parts in Poria, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Angelicae Sinensis, 10 parts on Pericarpium Citri Reticulatae Viride, conventional method decocts.
Embodiment 21 promotes the preparation () of the medicine three of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 15 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Angelicae Sinensis, 15 parts on Pericarpium Citri Reticulatae Viride, 5 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5.5 parts of Folium Sennae, conventional method decocts.
Embodiment 22 promotes the preparation (two) of the medicine three of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 5 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 15 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Et Rhizoma Rhei, 15 parts of Radix Angelicae Sinensis, 5 parts on Pericarpium Citri Reticulatae Viride, 15 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 3 parts of Folium Sennae, conventional method decocts.
Embodiment 23 promotes the preparation (three) of the medicine three of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 5 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 15 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Radix Et Rhizoma Rhei, 15 parts of Radix Angelicae Sinensis, 15 parts on Pericarpium Citri Reticulatae Viride, 5 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 3 parts of Folium Sennae, conventional method decocts.
Embodiment 24 promotes the preparation (four) of the medicine three of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Angelicae Sinensis, 5 parts on Pericarpium Citri Reticulatae Viride, 15 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5.5 parts of Folium Sennae, conventional method decocts.
Embodiment 25 promotes the preparation (five) of the medicine three of gastrointestinal function recovery
5 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Angelicae Sinensis, 15 parts on Pericarpium Citri Reticulatae Viride, 15 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5.5 parts of Folium Sennae, conventional method decocts.
Embodiment 26 promotes the preparation (six) of the medicine three of gastrointestinal function recovery
8 parts of Pericarpium Citri Reticulataes, 12 parts of the Radix Aucklandiae, 8 parts of Cortex Magnoliae Officinalis, 8 parts in Poria, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Et Rhizoma Rhei, 8 parts of Radix Angelicae Sinensis, 12 parts on Pericarpium Citri Reticulatae Viride, 12 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5.5 parts of Folium Sennae, conventional method decocts.
Embodiment 27 promotes the preparation (seven) of the medicine three of gastrointestinal function recovery
12 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 12 parts of Cortex Magnoliae Officinalis, 12 parts in Poria, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Angelicae Sinensis, 8 parts on Pericarpium Citri Reticulatae Viride, 8 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 3 parts of Folium Sennae, conventional method decocts.
Embodiment 28 promotes the preparation (eight) of the medicine three of gastrointestinal function recovery
15 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 12 parts of Cortex Magnoliae Officinalis, 8 parts in Poria, 5 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Angelicae Sinensis, 5 parts on Pericarpium Citri Reticulatae Viride, 12 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 3 parts of Folium Sennae, conventional method decocts.
Embodiment 29 promotes the preparation (nine) of the medicine three of gastrointestinal function recovery
Old 5 parts, 5 parts of the Radix Aucklandiae, 5 parts of Cortex Magnoliae Officinalis, 5 parts in Poria, 12 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Et Rhizoma Rhei, 8 parts of Radix Angelicae Sinensis, 8 parts on Pericarpium Citri Reticulatae Viride, 15 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5.5 parts of Folium Sennae, conventional method decocts.
Embodiment 30 promotes the preparation (ten) of the medicine three of gastrointestinal function recovery
10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Cortex Magnoliae Officinalis, 10 parts in Poria, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Angelicae Sinensis, 10 parts on Pericarpium Citri Reticulatae Viride, 10 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5 parts of Folium Sennae, conventional method decocts.
Need to prove that it is the conventional manufacture method of Chinese medicine decoction that the described conventional method of embodiment 1-30 decocts, and is about to described crude drug decocte with water and becomes decoction.
Embodiment 31 promotes the medicinal tablet/capsular preparation of gastrointestinal function recovery
Get the arbitrary described medicine of embodiment 1-30, add 9-11 times of water gaging, decocted 2-3.5 hour, leach medicine juice.Add 9 times of water gagings again, decocted 2.5 hours, leach medicine juice, merge the secondary decocting liquid, leave standstill, the leaching supernatant concentrates, and puts coldly, adds 3 times of amounts of concentrated solution ethanol, stirs deposition and spends the night.Get supernatant, be concentrated into thick extractum; Add pharmaceutical aids, vacuum drying is pulverized and is granulated, and is pressed into tablet or fills encapsulated.
Embodiment 32 promotes the preparation of the drug particles of gastrointestinal function recovery
Get the arbitrary described medicine of embodiment 1-30, add 8-10 times of water gaging, decocted 3 hours, leach medicine juice.Add 10 times of water gagings again, decocted 2.5 hours, leach medicine juice, merge the secondary decocting liquid, leave standstill, the leaching supernatant concentrates, and puts coldly, adds 2 times of amounts of concentrated solution ethanol, stirs deposition and spends the night.Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, granulate, drying, granulate gets the 20g granule, packing 10g/ bag.
Embodiment 33 promotes the preparation of the drug mixture/oral liquid/syrup of gastrointestinal function recovery
Get the arbitrary described medicine of embodiment 1-30, add 8-11 times of water gaging, decocted 3 hours, leach medicine juice.Add 8 times of water gagings again, decocted 3 hours, leach medicine juice, merge the secondary decocting liquid, leave standstill, the leaching supernatant concentrates, and puts coldly, adds 3.5 times of amounts of concentrated solution ethanol, stirs deposition and spends the night.Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, process mixture, oral liquid or syrup.
Embodiment 34 medicines of the present invention are to the observation of curative effect of ovarian cancer post operation restoration of gastrointestinal function
One, data and method
1. physical data
1～Decembers in 2009 are accepted inpatient 240 examples of ovarian cancer operation, age 31-80 year, The median age 55.62 years old.Wherein, 202 examples of performing the operation first, second operation 38 examples, anesthesia method is epidural anesthesia, the capable patient-controlled analgesia of postoperative (PCA).Postoperative is divided into following each group immediately: matched group, acupuncture group, documents drug group, medicine one add that acupuncture group, medicine two add the acupuncture group, medicine three adds the acupuncture group, every group 40 example, and each group has comparability aspect the basic documents such as age, stadium.
2. Therapeutic Method
(1) matched group: press the nursing of ovarian cancer post operation nursing routine, the conventional semireclining position of postoperative, fasting, gastrointestinal decompression, water, electrolyte and acid-base balance and intravenous nutrition are kept in intravenous applications antibiotic, fluid infusion, the postoperative early ambulant; (2) acupuncture group: in the conventional therapy nursing of matched group, give acupuncture, the acupuncture point selection tsu san li 2 times/d, is total to 5d; (3) documents drug group: in the conventional therapy nursing of matched group, give disclosed medication combined acupuncture in the documents, promptly Chinese medicine Pericarpium Citri Reticulatae, the Radix Aucklandiae, Cortex Magnoliae Officinalis, Poria, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae Viride, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are respectively 10 parts, 6 parts of Folium Sennae; Decocte with water to concentration is for containing crude drug amount 0.25g/mL, extracting juice 300ml, 100ml/ time; 3 times/d, postoperative 24h begins to be injected and folder closes stomach tube 2h by stomach tube, stops the clothes of withdrawing the previous remark after the gastrointestinal decompression; Obey 5 doses altogether; The acupuncture point selection tsu san li 2 times/d, is total to 5d; (4) medicine one adds the acupuncture group: in the conventional therapy nursing of matched group, give the medication combined acupuncture of embodiment 10 preparations, medicine decocte with water to the concentration of embodiment 10 is for containing crude drug amount 0.25g/mL, extracting juice 300ml; 100ml/ time, 3 times/d, postoperative 24h begins to close stomach tube 2h by stomach tube injection and folder; Stop the clothes of withdrawing the previous remark after the gastrointestinal decompression, obey 5 doses altogether, the acupuncture point selection tsu san li; 2 times/d, be total to 5d; (5) medicine two adds the acupuncture group: in the conventional therapy nursing of matched group, give the medication combined acupuncture of embodiment 20 preparations, medicine decocte with water to the concentration of embodiment 20 is for containing crude drug amount 0.25g/mL, extracting juice 300ml; 100ml/ time, 3 times/d, postoperative 24h begins to close stomach tube 2h by stomach tube injection and folder; Stop the clothes of withdrawing the previous remark after the gastrointestinal decompression, obey 5 doses altogether, the acupuncture point selection tsu san li; 2 times/d, be total to 5d; (6) medicine three adds the acupuncture group: in the conventional therapy nursing of matched group, give the medication combined acupuncture of embodiment 30 preparations, medicine decocte with water to the concentration of embodiment 30 is for containing crude drug amount 0.25g/mL, extracting juice 300ml; 100ml/ time, 3 times/d, postoperative 24h begins to close stomach tube 2h by stomach tube injection and folder; Stop the clothes of withdrawing the previous remark after the gastrointestinal decompression, obey 5 doses altogether, the acupuncture point selection tsu san li; 2 times/d, be total to 5d.
3. curative effect determinate standard
List of references: money state. purging FU-organs soup is to the influence [J] of abdominal postoperative gastrointestinal function. practical Chinese medicine magazine, 2007,10 (10): 618.Concrete criterion is following:
Produce effects: passage of gas by anus in the 12h borborygmus appears, in no abdominal distention; Effectively: do not have obvious abdominal distention, borborygmus is normal, passage of gas by anus in the 12-36h; Improve: slight abdominal distention, borborygmus is normal, passage of gas by anus in the 36-72h; Invalid: obvious abdominal distention is arranged, a little less than the borborygmus, the not aerofluxus of the above anus of 72h.
4. statistical procedures
Enumeration data is represented with percentage rate, adopts χ
2Check, P<0.05 for difference has statistical significance.
Two, result
Each organizes curative effect and the difference statistics is seen table 1.Data can be found out from table, and acupuncture group, documents drug group, medicine one add acupuncture group, medicine two and add acupuncture group, medicine three and add the acupuncture group and compare with matched group, and total effective rate is significantly increased, and difference has statistical significance; Medicine one adds acupuncture group, medicine two and adds acupuncture group, medicine three and add acupuncture group and acupuncture group relatively, and total effective rate is significantly increased, and difference has statistical significance, explains that medicine of the present invention can significantly promote the ovarian cancer post operation restoration of gastrointestinal function; Medicine one adds acupuncture group, medicine two and adds acupuncture group, medicine three and add the acupuncture group and compare with the documents drug group, and the difference not statistically significant is explained and adopted the less medicine of the present invention of flavour of a drug number can obtain excellent curative equally.
Table 1 is respectively organized curative effect relatively [example (%)]
| Group | The example number | Produce effects | Effectively | Improve | Invalid | Total effective rate |
| Matched group | 40 | 2（5.0） | 7（17.5） | 21（52.5） | 10（25.0） | 75% |
| The acupuncture group | 40 | 3（7.5） | 8（20.0） | 22（55.0） | 7（17.5） | 82.5% # |
| The documents drug group | 40 | 6（15.0） | 15（37.5） | 16（40.0） | 3（7.5） | 92.5% * |
| Medicine one adds the acupuncture group | 40 | 6（15.0） | 14（35.0） | 17（42.5） | 3（7.5） | 92.5% * |
| Medicine two adds the acupuncture group | 40 | 7（17.5） | 14（35.0） | 17（42.5） | 2（5.0） | 95.0% * |
| Medicine three adds the acupuncture group | 40 | 8（20.0） | 13（32.5） | 16（40.0） | 3（7.5） | 92.5% * |
Annotate: #, * represent that all difference has statistical significance, and P < 0.05.
In sum, medicine of the present invention has reduced the flavour of a drug number, has reduced cost; But still effect is obvious to the recovery of ovarian cancer operation back gastrointestinal function, and is more economical and practical, simple; Help the recovery of postoperative gastric intestinal function, can alleviate the patient suffering, promote patient's early recovery.
The above only is a preferred implementation of the present invention; Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the inventive method; Can also make some improvement and replenish, these improvement and replenish and also should be regarded as protection scope of the present invention.
Claims (10)
1. a medicine that promotes gastrointestinal function recovery is characterized in that, it mainly is to be processed by following bulk drugs: Pericarpium Citri Reticulatae 5-15 part, Radix Aucklandiae 5-15 part, Cortex Magnoliae Officinalis 5-15 part, Poria 5-15 part, Radix Salviae Miltiorrhizae 5-15 part, Radix Et Rhizoma Rhei 5-15 part.
2. medicine according to claim 1 is characterized in that, it mainly is to be processed by following bulk drugs: Pericarpium Citri Reticulatae 8-12 part, Radix Aucklandiae 8-12 part, Cortex Magnoliae Officinalis 8-12 part, Poria 8-12 part, Radix Salviae Miltiorrhizae 8-12 part, Radix Et Rhizoma Rhei 8-12 part.
3. medicine according to claim 1 is characterized in that, it mainly is to be processed by following bulk drugs: 10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Cortex Magnoliae Officinalis, 10 parts in Poria, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Et Rhizoma Rhei.
4. according to the arbitrary described medicine of claim 1-3, it is characterized in that it also comprises following bulk drugs: Radix Angelicae Sinensis 5-15 part, Pericarpium Citri Reticulatae Viride 5-15 part.
According to claim according to the arbitrary described medicine of claim 1-3, it is characterized in that it also comprises following bulk drugs: Radix Angelicae Sinensis 8-12 part, Pericarpium Citri Reticulatae Viride 8-12 part.
According to claim according to the arbitrary described medicine of claim 1-3, it is characterized in that it also comprises following bulk drugs: 10 parts of Radix Angelicae Sinensis, 10 parts on Pericarpium Citri Reticulatae Viride.
7. medicine according to claim 4 is characterized in that, it also comprises following bulk drugs: Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5-15 part, Folium Sennae 3-5.5 part.
8. medicine according to claim 7 is characterized in that, it also comprises following bulk drugs: 10 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 5 parts of Folium Sennae.
9. medicine according to claim 7 is characterized in that, the medicament of described medicine is capsule, granule, tablet, oral liquid, mixture or syrup.
10. like claim 1 or the application of 9 described medicines in the medicine of preparation promotion gastrointestinal function recovery.
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| CN102614283B (en) | 2013-12-04 |
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