CN102613548A - Diet therapy product capable of regulating blood pressure and preparation method thereof - Google Patents
Diet therapy product capable of regulating blood pressure and preparation method thereof Download PDFInfo
- Publication number
- CN102613548A CN102613548A CN2012100803576A CN201210080357A CN102613548A CN 102613548 A CN102613548 A CN 102613548A CN 2012100803576 A CN2012100803576 A CN 2012100803576A CN 201210080357 A CN201210080357 A CN 201210080357A CN 102613548 A CN102613548 A CN 102613548A
- Authority
- CN
- China
- Prior art keywords
- parts
- blood pressure
- clear cream
- diet therapy
- dietary product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of foods and relates to a food with a diet therapy function, in particular to a diet therapy product capable of regulating blood pressure and a preparation method thereof. The invention aims at overcoming the deficiencies of the prior art, taking medicinal and edible foods as raw materials and providing the diet therapy product which is convenient to take and can regulate the blood pressure and the preparation method thereof. The diet therapy product capable of regulating the blood pressure comprises the following components in parts by weight: 19-39 parts of kudzuvine root, 9.5-42 parts of chrysanthemum, 8.5-35 parts of cassia seed, 16.8-22 parts of hawthorn fruit, 3.2-30 parts of semen nelumbinis and 3-30 parts of emblic leafflower fruit, the diet therapy product selects natural and medicinal and edible traditional Chinese medicines for reasonable compatibility, and the modern pharmacological research proves that the diet therapy product is of the diet therapy product capable of regulating the blood pressure for patients with hypertension, can prevent complications, and condition and improve dietary structure, and further has the advantages of no side effects during long-term consumption, convenience, quickness, and capability of enhancing organism immunity; and furthermore, the diet therapy product is specially developed for the hypertension.
Description
Technical field
The invention belongs to food technology field, relate to a kind of food, particularly a kind of dietary product of regulating blood pressure and preparation method thereof with dietotherapy function.
Background technology
Hypertension has become global modal angiocardiopathy, also is that morbidity is maximum a kind of in China's cardiovascular and cerebrovascular disease, threatens very big to human beings'health; And can cause the decline of quality of life, in actual life, the elderly's illness rate is up to 25%-35%; And the speed that the annual incidence of disease rises is improving; The trend that rejuvenation was arranged on the age of morbidity, hypertension is high through the drug therapy cost, and the duration of taking medicine is very long; And be three fens poison of medicine, the harm not to be sneezed at that medicine causes human body when taking medicine.In the prior art, various to the medicine of preventing and treating high blood pressure, the dietary product of nursing one's health blood pressure in the market is rare; Be food be again that the product of medicine is rarer, along with the rapid raising of socioeconomic fast development and living standard, People more and more is paid attention to health and health care; The method that adopts drug therapy and dietetic treatment to combine for this treatment of diseases more, and advocate dietetic treatment especially, the dietary product of nursing one's health blood pressure in the market is rare; Though the product that has has certain effect; But all exist effect not remarkable, carry and drink inconvenience, the human intake measures few deficiency that waits; So be necessary theoretical and diet-therapy health-preserving theory according to the integration of drinking and medicinal herbs of the traditional Chinese medical science, develop a kind of industrial food of processing of new type functional modernization of instant of suitable people's needs.
Summary of the invention
The objective of the invention is to overcome the deficiency of prior art, be raw material, dietary product a kind of instant edible, that regulate blood pressure and preparation method thereof is provided with the food of dietotherapeutic.
A kind of dietary product of regulating blood pressure of the present invention, wherein: its dietary product of regulating blood pressure is formed as follows: root of kudzu vine 19-39 part, chrysanthemum 9.5-42 part, cassia seed 8.5-35 part, hawthorn 16.8-22 part, lotus seeds 3.2-30 part, emblic 3-30 part by weight.
The dietary product of adjusting blood pressure according to the invention, its dietary product of regulating blood pressure is formed as follows: root of kudzu vine 29-33 part, chrysanthemum 26-30 part, cassia seed 22-26 part, hawthorn 19-21 part, lotus seeds 17-22 part, emblic 17-22 part by weight.
The dietary product of adjusting blood pressure according to the invention, its dietary product of regulating blood pressure is preferably: its dietary product of regulating blood pressure is processed by following bulk drug: 29 parts of the roots of kudzu vine, 26 parts of chrysanthemums, 22 parts of cassia seeds, 21 parts of hawthorn, 22 parts in lotus seeds, 22 parts of emblics by weight.
The principles of formulating prescriptions of product of the present invention are: be made up of lotus seeds, emblic, cassia seed, chrysanthemum, the root of kudzu vine, hawthorn, wherein chrysanthemum wind and heat dispersing, flat liver make eye bright and are monarch, cassia seed clearing liver kidney-nourishing; The hawthorn promoting the circulation of qi stasis of blood of loosing; The root of kudzu vine promotes the production of body fluid, and benefit is cloudy to be minister, and assistant helps monarch with the lotus seeds mental-tranquilization, makes with the emblic coordinating the drug actions of a prescription; Full side plays flat irascibility, the effect of kidney-nourishing the moon altogether.
The present invention prepares the preparation method of the dietary product of said adjusting blood pressure, and wherein: concrete procedure of processing is following:
The root of kudzu vine, hawthorn, cassia seed, chrysanthemum are extracted three times with 80% alcohol reflux, and 8 times of each alcohol adding amounts each 1.5 hours, merge three times ethanol extract; Filter, from filtrate recycling ethanol, it is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes the clear cream of alcohol extracting, and some parts of some parts of the dregs of a decoction and lotus seeds, emblic are added 10 times of emerge in worm water half an hour; Decoct 2 times, each 2 hours, filter merging filtrate; Filtrating is concentrated into the clear cream of relative density 1.09-1.15 (70 ℃) to be become and decocts clear cream, stirs down in the time of will decocting clear cream and be chilled to 40 ℃ slowly to add ethanol, makes to contain the alcohol amount and reach 65% fully stirring; Left standstill 12 hours, the leaching supernatant reclaims ethanol; The clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes dense clear cream, and dense clear cream and the clear cream merging of said alcohol extracting spray-drying are processed the trickle powder of spraying, and other gets the residue lotus seeds, the some parts of emblic are ground into and pulverize fine powder; The trickle powder of will spraying adds dextrin with the trickle powder merging of pulverizing and mixes pelletizing press sheet bottling, every 0.4 gram/sheet in right amount; Amount is every day 3 times, each 3-5 sheet, warm water delivery service after the meal.The clear cream paste-forming rate of alcohol extracting according to the invention is 10%, and the paste-forming rate of the clear cream of said decoction is 11%-11.5%.
Prescription of the present invention is made up of lotus seeds, emblic, cassia seed, chrysanthemum, the root of kudzu vine, hawthorn, lotus seeds antitoxic heart-soothing and sedative in the prescription that the present invention adopted, and cassia seed clears liver and improve vision; Control headache, dizziness, chrysanthemum is controlled head's wind-heat, and it is dizzy to have a headache; Sharp blood vessels; Hawthorn row knot gas, the hemostasis that disappears, emblic clearing heat, relieving sore-throat; The present invention inherits traditional Chinese medicine traditional group fong theory, in conjunction with modern pharmacology research, and the biotechnology extraction elite of uses advanced, the hyperpietic that the high-quality effective components of Chinese medicinal of refining develops nurses one's health the dietary product of blood pressure; Wherein chrysanthemum wind and heat dispersing, flat liver make eye bright and are monarch, cassia seed clearing liver kidney-nourishing, the hawthorn promoting the circulation of qi stasis of blood of loosing; The root of kudzu vine promotes the production of body fluid, and benefit is cloudy to be minister, and assistant helps monarch with the lotus seeds mental-tranquilization, makes with the emblic coordinating the drug actions of a prescription; Full side plays flat irascibility altogether; The effect of kidney-nourishing the moon is utilized flavone compounds such as alkaloids such as containing liensinine, isoliensinine, Nuciferine in the lotus seeds and cyanidenon, rutin, hyperin, has antiarrhythmic effect and hypotensive effect; Utilizing emblic main component chebulinic acid, gallic acid etc., is a kind of natural lipopenicillinase, antihypertensive drugs, can increase myocardium glycogen levels, have spasmolysis and antiatherogenic effect; Utilize the cassia seed main component that archen, Rhein, aloe-emodin etc. are arranged, The pharmacological results shows that the hypotensive effect of cassia seed is similar with the Western medicine reserpine; Cassia seed can improve the content of HDL, and coronary heart disease is had protective effect; The chrysanthemum main component has borneol, acetic acid borneol fat, chrysanthanone etc., utilizes the chrysanthemum preparation that coronary flow is significantly increased, and improves the coronary artery microcirculation, and its effect surpasses the effect with the dosage red sage root; In clinical practice chrysanthemum preparation for treating high blood pressure, obtained good curative effect, the main component of Chinese hawthorn blood-pressure-reducing is Fructus Crataegi flavones or triterpenic acid, and root of kudzu vine ability hemangiectasis improves microcirculation, and the hypotensive effect of hawthorn is main with periphery blood vessel dilatation mainly.In sum, all medicine combinations have certain opsonic action to hypertension, cardiovascular and coronary heart disease etc.
The present invention has following remarkable advantage:
Prescription of the present invention is made up of lotus seeds, emblic, cassia seed, chrysanthemum, the root of kudzu vine, hawthorn, and wherein chrysanthemum wind and heat dispersing, flat liver make eye bright and be monarch, cassia seed clearing liver kidney-nourishing; The hawthorn promoting the circulation of qi stasis of blood of loosing, the root of kudzu vine are promoted the production of body fluid, and benefit is cloudy to be minister, and assistant helps monarch with the lotus seeds mental-tranquilization; Make with the emblic coordinating the drug actions of a prescription, full side plays flat irascibility, the effect of kidney-nourishing the moon altogether; Dietary product according to the invention is selected Chinese medicine reasonable compatibility natural, dietotherapeutic for use; Confirm through modern pharmacology research, but be a kind of dietary product complication prevention of regulating blood pressure of hyperpietic, nurse one's health and improve dietary structure; Long-term edible without any side effects, convenient and swift, enhancing body immunity, be the dietary product of developing for the hyperpietic specially.
The specific embodiment:
Embodiment one: a kind of dietary product of regulating blood pressure, its optimization formula is formed as follows: 29 parts of the roots of kudzu vine, 26 parts of chrysanthemums, 22 parts of cassia seeds, 21 parts of hawthorn, 22 parts in lotus seeds, 22 parts of emblics by weight.
The preparation method of the dietary product of described adjusting blood sugar is: concrete procedure of processing is following:
The first step: 29 parts of the roots of kudzu vine, 21 parts of hawthorn, 22 parts of cassia seeds, 26 parts of usefulness 80% alcohol refluxs of chrysanthemum are extracted three times 8 times of each alcohol adding amounts, each 1.5 hours; Obtain ethanol extract; Merge three times ethanol extract, filter, from the filtrating of ethanol extract, reclaim ethanol; It is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes the clear cream of alcohol extracting, and the dregs of a decoction are subsequent use;
Second step: 20 parts of the said dregs of a decoction, 20 parts in lotus seeds, emblic are added 10 times of emerge in worm water half an hour, decocts 2 times, each 2 hours, get decoction liquor and filter, merge to decoct and filtrate;
The 3rd step: said decoction filtrating is concentrated into the clear cream of relative density 1.09-1.15 (70 ℃) becomes the clear cream of decoction; Stir in the time of will decocting clear cream and be chilled to 40 ℃ again and slowly add ethanol down; Make the alcohol amount of containing reach 65% and fully stir, left standstill the leaching supernatant 12 hours; Reclaim ethanol, it is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes dense clear cream;
The 4th step: will said dense clear cream to become the fine powder of spraying subsequent use with the clear cream merging of said alcohol extracting spray-drying;
The 5th step: other gets 2 parts in 2 parts in lotus seeds, emblic and is ground into fine powder and constitutes that to pulverize fine powder subsequent use;
The 6th step: the fine powder of the fine powder of said spraying and said pulverizing merged add 0.5 part of dextrin and mix pelletizing press sheet bottling, every heavy 0.4 gram, every day 3 times, each 3-5 sheet, warm water delivery service after the meal.
Embodiment two: a kind of dietary product of regulating blood pressure, its optimization formula is formed as follows: 33 parts of the roots of kudzu vine, 30 parts of chrysanthemums, 26 parts of cassia seeds, 19 parts of hawthorn, 17 parts in lotus seeds, 17 parts of emblics by weight.
The preparation method of the dietary product of described adjusting blood sugar is: concrete procedure of processing is following:
The first step: 33 parts of the roots of kudzu vine, 19 parts of hawthorn, 26 parts of cassia seeds, 30 parts of usefulness 80% alcohol refluxs of chrysanthemum are extracted three times 8 times of each alcohol adding amounts, each 1.5 hours; Obtain ethanol extract; Merge three times ethanol extract, filter, from the filtrating of ethanol extract, reclaim ethanol; It is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes the clear cream of alcohol extracting, and the dregs of a decoction are subsequent use;
Second step: 15 parts of the said dregs of a decoction, 15 parts in lotus seeds, emblic are added 10 times of emerge in worm water half an hour, decocts 2 times, each 2 hours, get decoction liquor and filter, merge to decoct and filtrate;
The 3rd step: said decoction filtrating is concentrated into the clear cream of relative density 1.09-1.15 (70 ℃) becomes the clear cream of decoction; Stir in the time of will decocting clear cream and be chilled to 40 ℃ again and slowly add ethanol down; Make the alcohol amount of containing reach 65% and fully stir, left standstill the leaching supernatant 12 hours; Reclaim ethanol, it is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes dense clear cream;
The 4th step: will said dense clear cream to become the fine powder of spraying subsequent use with the clear cream merging of said alcohol extracting spray-drying;
The 5th step: other gets 2 parts in 2 parts in lotus seeds, emblic and is ground into fine powder and is called that to pulverize fine powder subsequent use;
The 6th step: the fine powder of the fine powder of said spraying and said pulverizing merged add 0.5 part of dextrin and mix pelletizing press sheet bottling, every heavy 0.4 gram, every day 3 times, each 3-5 sheet, warm water delivery service after the meal.
Embodiment three: a kind of dietary product of regulating blood pressure, its dietary product prescription of regulating blood pressure is formed as follows: 39 parts of the roots of kudzu vine, 30 parts in lotus seeds, 30 parts of emblics, 22 parts of hawthorn, 8.5 parts of cassia seeds, 9.5 parts of chrysanthemums by weight.
The preparation method of the dietary product of described adjusting blood pressure is: concrete procedure of processing is following:
The first step: 39 parts of the roots of kudzu vine, 22 parts of hawthorn, 8.5 parts of cassia seeds, 9.5 parts of usefulness 80% alcohol refluxs of chrysanthemum are extracted three times 8 times of each alcohol adding amounts, each 1.5 hours; Obtain ethanol extract; Merge three times ethanol extract, filter, from the filtrating of ethanol extract, reclaim ethanol; It is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes the clear cream of alcohol extracting, and the dregs of a decoction are subsequent use;
Second step: 28 parts of the said dregs of a decoction, 28 parts in lotus seeds, emblic are added 10 times of emerge in worm water half an hour, decocts 2 times, each 2 hours, get decoction liquor and filter, merge to decoct and filtrate;
The 3rd step: said decoction filtrating is concentrated into the clear cream of relative density 1.09-1.15 (70 ℃) becomes the clear cream of decoction; Stir when the clear cream of said decoction is chilled to 40 ℃ again and slowly add ethanol down; Make the alcohol amount of containing reach 65% and fully stir, left standstill the leaching supernatant 12 hours; Reclaim ethanol, it is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes dense clear cream;
The 4th step: will said dense clear cream to become the fine powder of spraying subsequent use with the clear cream merging of said alcohol extracting spray-drying;
The 5th step: other gets 2 parts in 2 parts in lotus seeds, emblic and is ground into fine powder and becomes that to pulverize fine powder subsequent use;
The 6th step: the fine powder of the fine powder of said spraying and said pulverizing merged add 0.5 part of dextrin and mix pelletizing press sheet bottling, every heavy 0.4 gram, every day 3 times, each 3-5 sheet, warm water delivery service after the meal.
Embodiment four: a kind of dietary product of regulating blood pressure, its dietary product prescription of regulating blood pressure is formed as follows: 19 parts of the roots of kudzu vine, 3.2 parts in lotus seeds, 3 parts of emblics, 16.8 parts of hawthorn, 35 parts of cassia seeds, 42 parts of chrysanthemums by weight.
The preparation method of the dietary product of described adjusting blood pressure is: concrete procedure of processing is following:
The first step: 19 parts of the roots of kudzu vine, 16.8 parts of hawthorn, 35 parts of cassia seeds, 42 parts of usefulness 80% alcohol refluxs of chrysanthemum are extracted three times 8 times of each alcohol adding amounts, each 1.5 hours; Obtain ethanol extract; Merge three times ethanol extract, ethanol extract filters, and from the filtrating of ethanol extract, reclaims ethanol; It is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes the clear cream of alcohol extracting, and the dregs of a decoction are subsequent use;
Second step: 2 parts of the said dregs of a decoction, 2.2 parts in lotus seeds, emblic are added 10 times of emerge in worm water half an hour, decocts 2 times, each 2 hours, decoction liquor filtered, and merged to decoct filtrating, decocted filtrating and was concentrated into the clear cream of relative density 1.09-1.15 (70 ℃) and becomes the clear cream of decoction;
The 3rd step: stir when the clear cream of said decoction is chilled to 40 ℃ down and slowly add ethanol, make to contain the alcohol amount and reach 65% and fully stir, left standstill 12 hours, the leaching supernatant reclaims ethanol, and it is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes dense clear cream;
The 4th step: said dense clear cream and the clear cream merging of said alcohol extracting spray-drying are processed the fine powder of spraying;
The 5th step: other gets 1 part in lotus seeds, emblic is ground into fine powder for 1 part and processes the fine powder of pulverizing;
The 6th step: the fine powder of will spraying adds dextrin with the fine powder merging of pulverizing and mixes for 0.5 part, pelletizing press sheet bottling, every heavy 0.4 gram, every day 3 times, each 3-5 sheet, warm water delivery service after the meal.
Embodiment five: a kind of dietary product of regulating blood pressure, its dietary product prescription of regulating blood pressure is formed as follows: 20 parts of the roots of kudzu vine, 16.7 parts in lotus seeds, 16.5 parts of emblics, 19.4 parts of hawthorn, 22 parts of cassia seeds, 26.25 parts of chrysanthemums by weight.
The preparation method of the dietary product of the described adjusting blood pressure of present embodiment is: concrete procedure of processing is following:
The first step: 20 parts of the roots of kudzu vine, 19.4 parts of hawthorn, 22 parts of cassia seeds, 26.25 parts of usefulness 80% alcohol refluxs of chrysanthemum are extracted three times 8 times of each alcohol adding amounts, each 1.5 hours; Obtain ethanol extract; Merge three times ethanol extract, ethanol extract filters, and from the filtrating of ethanol extract, reclaims ethanol; It is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes the clear cream of alcohol extracting, and the dregs of a decoction are subsequent use;
Second step: 14 parts of the said dregs of a decoction, 14 parts in lotus seeds, emblic are added 10 times of emerge in worm water half an hour; Decoct 2 times, each 2 hours, get decoction liquor and filter; Merge to decoct filtrating, said decoction filtrating is concentrated into the clear cream of relative density 1.09-1.15 (70 ℃) becomes that to decoct clear cream subsequent use;
The 3rd step: stir when the clear cream of said decoction is chilled to 40 ℃ down and slowly add ethanol, make to contain the alcohol amount and reach 65% and fully stir, left standstill 12 hours, the leaching supernatant reclaims ethanol, and it is subsequent use that the clear cream that is concentrated into relative density 1.19-1.35 (50 ℃) becomes dense clear cream;
The 4th step: said dense clear cream and the clear cream merging of said alcohol extracting spray-drying are processed the fine powder of spraying;
The 5th step: other gets 2.7 parts in lotus seeds, emblic is ground into fine powder for 2.5 parts and processes the fine powder of pulverizing;
The 6th step: the fine powder of the fine powder of said spraying and said pulverizing merged add dextrin and mix pelletizing press sheet bottling, every heavy 0.4 gram, every day 3 times, each 3-5 sheet, warm water delivery service after the meal for 0.5 part.
The clear cream paste-forming rate of alcohol extracting of the present invention is 10%, and the paste-forming rate that decocts clear cream is 11%-11.5%.
Confirm through modern pharmacology research; Dietary product with the Chinese medicine preparation has good action to hypertension and complication thereof, and prescription of the present invention is made up of lotus seeds, emblic, cassia seed, chrysanthemum, the root of kudzu vine, hawthorn, and wherein chrysanthemum wind and heat dispersing, flat liver make eye bright and be monarch; Be that the chrysanthemum main component has borneol, acetic acid borneol fat, chrysanthanone etc.; The chrysanthemum preparation can make coronary flow significantly increase, and improves the coronary artery microcirculation, and its effect surpasses the effect with the dosage red sage root; Use chrysanthemum preparation for treating high blood pressure, obtained good curative effect; Cassia seed clearing liver kidney-nourishing; The hawthorn promoting the circulation of qi stasis of blood of loosing; The root of kudzu vine promotes the production of body fluid, and benefit is cloudy to be minister, and the cassia seed main component has archen, Rhein, aloe-emodin etc., and The pharmacological results shows that the hypotensive effect of cassia seed is similar with the Western medicine reserpine; Cassia seed also can improve the content of HDL, and coronary heart disease is had protective effect; The main component of Chinese hawthorn blood-pressure-reducing is Fructus Crataegi flavones or triterpenic acid, and the hypotensive effect of hawthorn is main with periphery blood vessel dilatation mainly, and the root of kudzu vine can hemangiectasis, improves microcirculation; And assistant helps monarch with the lotus seeds mental-tranquilization, contains flavone compounds such as alkaloid such as liensinine, isoliensinine, Nuciferine and cyanidenon, rutin, hyperin in the lotus seeds, has antiarrhythmic effect and hypotensive effect; Make with the emblic coordinating the drug actions of a prescription, emblic main component chebulinic acid, gallic acid etc. are a kind of natural lipopenicillinase, antihypertensive drugs, can increase myocardium glycogen levels, have spasmolysis and antiatherogenic effect; Therefore, full side plays flat irascibility altogether, the effect of kidney-nourishing the moon, and all medicines make up has certain function to hypertension, cardiovascular and coronary heart disease etc., convenient and swift, and complication prevention is nursed one's health and improved dietary structure, and is without any side effects.
The present invention is according to the standard of clinical nutriology, according to hypertension clinical disease illness, select State Food and Drug Administration's regulation respectively for use be food be again the Chinese medicine of medicine, defer to the traditional Chinese medicine theory; Monarch, minister, the medicine compatibility method of helping, making carry out prescription, the technology of uses advanced, extraction elite, the product that refining active ingredient is processed; Nutrition adds conditioning, complements each other, and takes good care of healthy tendency, YIN and YANG balance regulating; Safe and reliable, instant, mouthfeel is good, closes in law; Health consolidates, and reaches the purpose of " healthy tendency internal memory, heresy can not be done ".
From the chemical composition of dietary product of the present invention and general pharmacology in general, reasonable recipe of the present invention, medication is appropriate; Promoted the synergy between each medicine; Guaranteeing has increased curative effect by drug safety, below through relevant pharmacological research that tablet of the present invention carried out; Further set forth the beneficial effect of dietary product according to the invention, concrete material, method and result are following:
Test material: receiving trial product is a kind of dietary product of regulating sleep of anthology invention, the 0.4g/ sheet, and planting hundred osmanthus Bioisystech Co., Ltd by sky, Beijing provides, and lot number is: 20110505.
1. dosage design: the clinical consumption per day of product tablet people of the present invention is: 6.0g, to calculate by 60 kg body weight, and dosage is the 0.1g/kg body weight; In the conversion of animals and human beings kg body weight ratio, rat dosage is 2.16g/kg body weight, 1.08g/kg body weight, three dosage of 0.54g/kg body weight, and low dosage is equivalent to clinical equivalent dosage, and middle dosage is the twice of low dosage, and high dose is 2 times of middle dosage.The clinical consumption per day of positive control drug is 40mg, is converted into the 0.67mg/kg body weight, and rat consumption 7.2mg/kg is the twice of clinical equivalent dosage.
2. animal: the SD rat, body weight 200-220g, male.
3. instrument: non-invasive blood pressure measuring system.
Test method:
Select 75 of 200-220g healthy rats for use, 10 of normal group, all the other are divided into 5 groups at random; Being respectively model control group, positive controls, product of the present invention, high, medium and low (three dose groups of 11.4g, 5.7g, 2.9g biology/kg), 13 every group at first by only measuring blood pressure twice, are averaged as the basic blood pressure value; With 30mg/kg yellow Jackets intraperitoneal injection of anesthesia rat (pressing 0.1m l/100g body weight), the about 2cm of belly left side kidney side otch is behind the nearly hilus renalis of the left kidney place careful separation arteria renalis then; Get silver brain clip; The arteria renalis is slipped into the silver brain clip opening, suture muscles and skin successively, and lumbar injection penicillin 20,000 units/only.Two weeks of postoperative, measure blood pressure, choose blood pressure than more than the preceding rising 30mmHg of operation and above 130mmHg person; Adjustment between organizing, 10 every group of adjustment backs, each group begins to irritate respectively the stomach medication; Once a day, irritating the stomach volume is the 1.0ml/100g body weight, 3 weeks of successive administration.Respectively at 1,2,3 weeks behind the medicine measuring rat blood pressure.Between organizing with t check relatively.
Table 1: the dietary product that the present invention regulates blood pressure causes influence
n=10 of rat hypertension model blood pressure to RAS) annotate: compare * p＜0.05 with the blank group, * * p＜0.01;
Annotate: compare * p＜0.05 with model control group, * * p＜0.01;
Result of the test: visible by table 1; Rat blood pressure all raises after two weeks of modeling; Mean value in 3 weeks after the administration, is surveyed rat blood pressure value administration group weekly and all is starkly lower than model control group more than 30mmhg; The 3rd all institutes amount of reagent group (2.16g, 1.08g, 0.54g/kg body weight) rat blood pressure has been compared remarkable reduction behind the medicine with model control group, and the blood pressure that shows the rat hypertension model that dietary product that the present invention regulates blood pressure causes RAS raises certain inhibitory action is arranged.
Brief summary: a kind of dietary product of regulating blood pressure of the present invention is made up of the root of kudzu vine, chrysanthemum, cassia seed, hawthorn, lotus seeds, emblic, irritates stomach with product 2.16g of the present invention, 1.08g, 0.54g crude drug/kg body weight and gives rat, continuous 3 weeks.Result of the test shows that the dietary product institute amount of reagent that the present invention regulates blood pressure can obviously reduce because the blood pressure of the rat hypertension model that RAS causes raises, and shows that this is tried thing and has certain hypotensive effect.
Claims (4)
1. dietary product of regulating blood pressure is characterized in that: its dietary product of regulating blood pressure is processed by following bulk drug: root of kudzu vine 19-39 part, chrysanthemum 9.5-42 part, cassia seed 8.5-35 part, hawthorn 16.8-22 part, lotus seeds 3.2-30 part, emblic 3-30 part by weight.
2. the dietary product of adjusting blood pressure according to claim 1 is characterized in that: its dietary product of regulating blood pressure is processed by following bulk drug: root of kudzu vine 29-33 part, chrysanthemum 26-30 part, cassia seed 22-26 part, hawthorn 19-21 part, lotus seeds 17-22 part, emblic 17-22 part by weight.
3. the dietary product of adjusting blood pressure according to claim 1 is characterized in that: its dietary product of regulating blood pressure is processed by following bulk drug: 29 parts of the roots of kudzu vine, 26 parts of chrysanthemums, 22 parts of cassia seeds, 21 parts of hawthorn, 22 parts in lotus seeds, 22 parts of emblics by weight.
4. prepare the dietary product method of claim 1 or 2 or 3 said adjusting blood pressures, it is characterized in that: this method comprises by following concrete procedure of processing and forming: the root of kudzu vine, hawthorn, cassia seed, chrysanthemum are extracted three times 8 times of each alcohol adding amounts with 80% alcohol reflux; Each 1.5 hours, merge three times ethanol extract, filter; Filtrate recycling ethanol, it is subsequent use that the clear cream of relative density 1.19-1.35 becomes the clear cream of alcohol extracting when being concentrated into 50 ℃, and the dregs of a decoction, lotus seeds, emblic are added 10 times of emerge in worm water half an hour; Decoct 2 times, each 2 hours, filter; Merging filtrate, the clear cream of relative density 1.09-1.15 became the clear cream of decoction when filtrating was concentrated into 70 ℃, stirred when the clear cream of said decoction is chilled to 40 ℃ slowly to add ethanol down; Make the alcohol amount of containing reach 65% and fully stir, left standstill the leaching supernatant 12 hours; Reclaim ethanol, the clear cream of relative density 1.19-1.35 becomes dense clear cream when being concentrated into 50 ℃, and said dense clear cream and the clear cream merging of said alcohol extracting spray-drying are become the fine powder of spraying; Other gets some parts of lotus seeds, emblic and is crushed into and pulverizes fine powder, the fine powder of said spraying and the fine powder of said pulverizing is merged add dextrin and mix the pelletizing press sheet bottling in right amount.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100803576A CN102613548A (en) | 2012-03-15 | 2012-03-15 | Diet therapy product capable of regulating blood pressure and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100803576A CN102613548A (en) | 2012-03-15 | 2012-03-15 | Diet therapy product capable of regulating blood pressure and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102613548A true CN102613548A (en) | 2012-08-01 |
Family
ID=46554025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100803576A Withdrawn CN102613548A (en) | 2012-03-15 | 2012-03-15 | Diet therapy product capable of regulating blood pressure and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102613548A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102907521A (en) * | 2012-11-09 | 2013-02-06 | 乐山逸凡农产品开发有限公司 | Healthy tea and preparation method thereof |
| CN106039049A (en) * | 2016-07-08 | 2016-10-26 | 重庆诚康福科技开发有限责任公司 | Traditional Chinese medicine for regulating blood pressure and preparation method thereof |
| CN107624935A (en) * | 2017-10-25 | 2018-01-26 | 贵州金黔汇源食品有限公司 | A kind of mountain Pueraria lobota ginkgo leave tea and preparation method |
| CN114010773A (en) * | 2021-10-26 | 2022-02-08 | 江苏协合转化医学研究院有限公司 | Composition formula for reducing blood pressure without side effect and preparation process and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86107160A (en) * | 1986-10-28 | 1987-04-22 | 赵元藩 | The preparation method of a kind of emblic (Yunnan olive) beverage |
| CN1205219A (en) * | 1997-07-16 | 1999-01-20 | 有维范 | Tea for reducing hypertension and fat |
| CN101161117A (en) * | 2007-11-21 | 2008-04-16 | 北京中科雍和医药技术有限公司 | Nutrition health products with function of decreasing blood pressure and improving cardio-cerebralvascular as well as its preparing method |
| CN101822749A (en) * | 2010-01-28 | 2010-09-08 | 窦啟玲 | Medicinal preparation for curing hypertension and hyperlipaemia and preparation method thereof |
| CN102742831A (en) * | 2011-04-18 | 2012-10-24 | 北京天植百桂生物技术有限公司 | Dietetic therapy product for regulating blood pressure and preparation method thereof |
-
2012
- 2012-03-15 CN CN2012100803576A patent/CN102613548A/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86107160A (en) * | 1986-10-28 | 1987-04-22 | 赵元藩 | The preparation method of a kind of emblic (Yunnan olive) beverage |
| CN1205219A (en) * | 1997-07-16 | 1999-01-20 | 有维范 | Tea for reducing hypertension and fat |
| CN101161117A (en) * | 2007-11-21 | 2008-04-16 | 北京中科雍和医药技术有限公司 | Nutrition health products with function of decreasing blood pressure and improving cardio-cerebralvascular as well as its preparing method |
| CN101822749A (en) * | 2010-01-28 | 2010-09-08 | 窦啟玲 | Medicinal preparation for curing hypertension and hyperlipaemia and preparation method thereof |
| CN102742831A (en) * | 2011-04-18 | 2012-10-24 | 北京天植百桂生物技术有限公司 | Dietetic therapy product for regulating blood pressure and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102907521A (en) * | 2012-11-09 | 2013-02-06 | 乐山逸凡农产品开发有限公司 | Healthy tea and preparation method thereof |
| CN106039049A (en) * | 2016-07-08 | 2016-10-26 | 重庆诚康福科技开发有限责任公司 | Traditional Chinese medicine for regulating blood pressure and preparation method thereof |
| CN107624935A (en) * | 2017-10-25 | 2018-01-26 | 贵州金黔汇源食品有限公司 | A kind of mountain Pueraria lobota ginkgo leave tea and preparation method |
| CN114010773A (en) * | 2021-10-26 | 2022-02-08 | 江苏协合转化医学研究院有限公司 | Composition formula for reducing blood pressure without side effect and preparation process and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102640926B (en) | Dietary therapy product for regulating sleep and preparation method thereof | |
| CN102907604B (en) | Health-care product having effects of reducing blood sugar and pressure, losing weight, relaxing bowels, maintaining beauty and resisting fatigue and production process thereof | |
| CN102178314B (en) | Bitter buckwheat health care beverage with auxiliary function for lowering blood pressure and production process thereof | |
| CN103877263B (en) | A kind of antifatigue health preparation of the compound Chinese medicine such as red ginseng, maca, green-tea extract (theanine) | |
| CN102742833B (en) | Dietetic therapy product for protecting heart and preparation method thereof | |
| CN103948031B (en) | A kind of deficiency of yang physique health food and preparation method thereof | |
| CN101161117A (en) | Nutrition health products with function of decreasing blood pressure and improving cardio-cerebralvascular as well as its preparing method | |
| CN104173493A (en) | Pharmaceutical composition with effect of improving sleep as well as preparation method and application of pharmaceutical composition | |
| CN103169793B (en) | Medicine for treating hypertension, hyperlipoidemia and diabetes mellitus | |
| CN106343567A (en) | Noni oral liquid and preparing method thereof | |
| CN104673578A (en) | SOD wine with health efficacy and preparation method of SOD wine | |
| CN103948029B (en) | A kind of yin-deficiency constitution protective foods and its preparation method | |
| CN102613548A (en) | Diet therapy product capable of regulating blood pressure and preparation method thereof | |
| CN101744970B (en) | Medicine used for type 2 diabetes and preparation method thereof | |
| CN103330175B (en) | Seasoning made of natural plant compositions and preparation method thereof | |
| CN101711840B (en) | Medicine-food dual-purpose composition suitable for cancerous patients and preparation method thereof | |
| CN102048215B (en) | Health beverage and preparation method thereof | |
| CN101385536A (en) | Natural plant hypoglycemic effervescent beverages | |
| CN102742831B (en) | A kind of dietary product regulating blood pressure and preparation method thereof | |
| CN100382832C (en) | Health foods in use for improving symptom in climacteric period of female and fabricating method | |
| CN101623365B (en) | Tuckahoe spleen-strengthening granules and preparation method thereof | |
| CN105733880A (en) | Composite hazelnut wine brewed from hazelnut meal | |
| CN102613547A (en) | Diet therapy product capable of protecting heart and preparation method thereof | |
| CN102188642A (en) | Weight-losing and body-building health-care wine and preparation method thereof | |
| CN102742830A (en) | Dietetic therapy product for regulating blood sugar and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C04 | Withdrawal of patent application after publication (patent law 2001) | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20120801 |