CN102576012B - 用于肾损伤和肾衰竭的诊断及预后方法和组合物 - Google Patents

用于肾损伤和肾衰竭的诊断及预后方法和组合物 Download PDF

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Publication number
CN102576012B
CN102576012B CN201080043037.2A CN201080043037A CN102576012B CN 102576012 B CN102576012 B CN 102576012B CN 201080043037 A CN201080043037 A CN 201080043037A CN 102576012 B CN102576012 B CN 102576012B
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Chinese (zh)
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CN102576012A (zh
Inventor
J·安德贝里
J·格雷
P·麦克弗森
K·中村
J·P·坎普夫
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Astute Medical Inc
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Astute Medical Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7452—Thrombomodulin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201080043037.2A 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物 Expired - Fee Related CN102576012B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510401130.0A CN105004864B (zh) 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US24400009P 2009-09-18 2009-09-18
US24399509P 2009-09-18 2009-09-18
US61/243,995 2009-09-18
US61/244,000 2009-09-18
US25463609P 2009-10-23 2009-10-23
US61/254,636 2009-10-23
PCT/US2010/049234 WO2011035097A1 (en) 2009-09-18 2010-09-17 Methods and composition for diagnosis and prognosis of renal injury and renal failure

Related Child Applications (1)

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CN201510401130.0A Division CN105004864B (zh) 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物

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CN102576012A CN102576012A (zh) 2012-07-11
CN102576012B true CN102576012B (zh) 2015-07-15

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CN201510401130.0A Expired - Fee Related CN105004864B (zh) 2009-09-18 2010-09-17 用于肾损伤和肾衰竭的诊断及预后方法和组合物

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Country Status (10)

Country Link
US (2) US20130045494A1 (https=)
EP (2) EP2470904A4 (https=)
JP (3) JP2013513086A (https=)
CN (2) CN102576012B (https=)
AU (2) AU2010295512B2 (https=)
CA (1) CA2773905A1 (https=)
EA (1) EA201290106A1 (https=)
MX (1) MX2012003168A (https=)
NZ (2) NZ612673A (https=)
WO (1) WO2011035097A1 (https=)

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US20160147958A1 (en) * 2013-07-26 2016-05-26 Koninklijke Philips N.V. Computerization and visualization of clinical rules and definitions for patient monitoring systems
GB201501597D0 (en) * 2015-01-30 2015-03-18 Randox Lab Ltd Thrombomodulin
JP6232689B2 (ja) 2015-06-25 2017-11-22 株式会社国際電気通信基礎技術研究所 多器官連関システムを基盤とした予測装置、及び予測プログラム
US20190033325A1 (en) * 2016-01-29 2019-01-31 Advanced Telecommunications Research Institute International Renal function evaluating device, device for predicting onset of kidney disease complications, and phosphorous ingestion amount estimating device
CN114594268A (zh) 2016-03-29 2022-06-07 无限生物制药公司 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法
EP3466446B1 (en) 2016-03-29 2023-12-27 Karydo Therapeutix, Inc. Pharmaceutical composition or food composition, and method for assessing effect of active ingredient in vivo

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Also Published As

Publication number Publication date
JP6403712B2 (ja) 2018-10-10
CN105004864A (zh) 2015-10-28
JP2013513086A (ja) 2013-04-18
JP2015129764A (ja) 2015-07-16
MX2012003168A (es) 2012-05-08
EP2470904A4 (en) 2013-05-01
CN105004864B (zh) 2017-11-03
EP2470904A1 (en) 2012-07-04
JP2016176953A (ja) 2016-10-06
US20190250170A1 (en) 2019-08-15
HK1167889A1 (zh) 2012-12-14
WO2011035097A1 (en) 2011-03-24
NZ598741A (en) 2013-07-26
US20130045494A1 (en) 2013-02-21
AU2015200953A1 (en) 2015-03-12
HK1212774A1 (zh) 2016-06-17
AU2010295512B2 (en) 2014-12-18
AU2010295512A1 (en) 2012-04-05
CN102576012A (zh) 2012-07-11
NZ612673A (en) 2014-10-31
CA2773905A1 (en) 2011-03-24
EP3299821A1 (en) 2018-03-28
EA201290106A1 (ru) 2012-12-28

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