EA201290106A1 - Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности - Google Patents

Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности

Info

Publication number
EA201290106A1
EA201290106A1 EA201290106A EA201290106A EA201290106A1 EA 201290106 A1 EA201290106 A1 EA 201290106A1 EA 201290106 A EA201290106 A EA 201290106A EA 201290106 A EA201290106 A EA 201290106A EA 201290106 A1 EA201290106 A1 EA 201290106A1
Authority
EA
Eurasian Patent Office
Prior art keywords
kidney damage
compositions
methods
prediction
diagnosis
Prior art date
Application number
EA201290106A
Other languages
English (en)
Russian (ru)
Inventor
Джозеф Андерберг
Джефф Грей
Пол Макферсон
Кевин Накамура
Джеймс Патрик Кампф
Original Assignee
Астьют Медикал, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астьют Медикал, Инк. filed Critical Астьют Медикал, Инк.
Publication of EA201290106A1 publication Critical patent/EA201290106A1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7452—Thrombomodulin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EA201290106A 2009-09-18 2010-09-17 Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности EA201290106A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24400009P 2009-09-18 2009-09-18
US24399509P 2009-09-18 2009-09-18
US25463609P 2009-10-23 2009-10-23
PCT/US2010/049234 WO2011035097A1 (en) 2009-09-18 2010-09-17 Methods and composition for diagnosis and prognosis of renal injury and renal failure

Publications (1)

Publication Number Publication Date
EA201290106A1 true EA201290106A1 (ru) 2012-12-28

Family

ID=43759017

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201290106A EA201290106A1 (ru) 2009-09-18 2010-09-17 Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности

Country Status (10)

Country Link
US (2) US20130045494A1 (https=)
EP (2) EP3299821A1 (https=)
JP (3) JP2013513086A (https=)
CN (2) CN105004864B (https=)
AU (2) AU2010295512B2 (https=)
CA (1) CA2773905A1 (https=)
EA (1) EA201290106A1 (https=)
MX (1) MX2012003168A (https=)
NZ (2) NZ598741A (https=)
WO (1) WO2011035097A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103874923B (zh) * 2011-08-26 2016-09-14 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物
EP3025263A2 (en) * 2013-07-26 2016-06-01 Koninklijke Philips N.V. Computerization and visualization of clinical rules and definitions for patient monitoring systems.
GB201501597D0 (en) * 2015-01-30 2015-03-18 Randox Lab Ltd Thrombomodulin
WO2016208776A1 (ja) 2015-06-25 2016-12-29 株式会社国際電気通信基礎技術研究所 多器官連関システムを基盤とした予測装置、及び予測プログラム
EP3410119B1 (en) * 2016-01-29 2021-03-17 Karydo Therapeutix, Inc. Renal function evaluating device, device for predicting onset of kidney disease complications, and phosphorous ingestion amount estimating device
JP6432962B2 (ja) 2016-03-29 2018-12-05 株式会社国際電気通信基礎技術研究所 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法
EP3466446B1 (en) 2016-03-29 2023-12-27 Karydo Therapeutix, Inc. Pharmaceutical composition or food composition, and method for assessing effect of active ingredient in vivo

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
JPH0736019B2 (ja) * 1989-12-27 1995-04-19 富士薬品工業株式会社 新規な抗ヒトトロンボモジュリンモノクローナル抗体によるヒトトロンボモジュリンおよびその分解産物の定量方法
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
CA2072758A1 (en) 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
CA2107894C (en) 1991-04-10 2003-10-14 Kenneth F. Buechler Crosstalk inhibitors and their uses
EP0579767B1 (en) 1991-04-11 2000-08-23 Biosite Diagnostics Inc. Novel conjugates and assays for simultaneous detection of multiple ligands
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US6019944A (en) 1992-05-21 2000-02-01 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
CN1129666C (zh) * 1994-12-13 2003-12-03 人体基因组科学有限公司 金属蛋白酶－4的人组织抑制剂
US6544761B2 (en) * 1994-12-13 2003-04-08 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
CN1495258A (zh) * 1994-12-13 2004-05-12 人体基因组科学有限公司 金属蛋白酶-4的人组织抑制剂
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
AU2094101A (en) * 1999-12-13 2001-06-18 Duanqing Pei Leukolysin/mmp25/mt6-mmp
JP2004535765A (ja) * 2000-12-07 2004-12-02 カイロン コーポレイション 前立腺癌においてアップレギュレートされた内因性レトロウイルス
US20040241744A1 (en) * 2001-07-12 2004-12-02 Hiroaki Kohno Method of quantifying denatured lipoprotein, reagents for quantifying denatured lipoprotein, method of detecting circulatory disease and reagents for detecting circulatory disease
CA2561835A1 (en) * 2004-03-30 2005-10-13 Den Kgl. Veterinaer-Og Landbohojskole Improvements in cancer treatment and cancer treatment efficacy prediction by blocking and detecting protease inhibitors
US7713693B1 (en) * 2004-09-01 2010-05-11 University Of Louisiana At Monroe Human cancer cell specific gene transcript
US20060160112A1 (en) * 2004-12-02 2006-07-20 Erdal Cavusoglu Tissue inhibitor of metalloproteinase (TIMP) as a marker and predictor of cardiovascular disease and both cardiac and non-cardiac mortality
US20090178145A1 (en) * 2005-05-11 2009-07-09 The Procter & Gamble Company Methods and targets for identifying compounds for regulating angiogenesis
WO2007053610A2 (en) * 2005-11-01 2007-05-10 The Regents Of The University Of California Methods of treating atrial fibrillation wtih pirfenidone
JP2007163151A (ja) * 2005-12-09 2007-06-28 Kitasato Gakuen 対象生物の生理状態を判定する方法
US8790871B2 (en) * 2006-05-09 2014-07-29 Musc Foundation For Research Development Detecting diastolic heart failure by protease and protease inhibitor plasma profiling
CN101490273A (zh) * 2006-05-09 2009-07-22 南卡罗来纳州医科大学研究发展基金会 利用蛋白酶和蛋白酶抑制剂血浆分析检测舒张期心力衰竭
WO2008084331A2 (en) * 2006-06-21 2008-07-17 Hopitaux Universitaires De Geneve Biomarkers for renal disorders
KR20090046825A (ko) * 2006-07-11 2009-05-11 무스크 파운데이션 포 리서치 디벨롭먼트 프로테아제 및 프로테아제 저해제 프로파일링으로 심근 경색 후 심부전을 예측하는 방법
GB0617429D0 (en) * 2006-09-05 2006-10-18 Electrophoretics Ltd Markers of renal transplant rejection and renal damage
WO2008060607A2 (en) * 2006-11-14 2008-05-22 Biosite Incorporated Methods and compositions for monitoring and risk prediction in cardiorenal syndrome
FR2909180B1 (fr) * 2006-11-29 2009-02-20 Diagnostica Stago Soc Par Acti Methode de mesure fonctionnelle de l'activite de la thrombomoduline plasmatique.

Also Published As

Publication number Publication date
MX2012003168A (es) 2012-05-08
EP3299821A1 (en) 2018-03-28
JP6403712B2 (ja) 2018-10-10
AU2015200953A1 (en) 2015-03-12
JP2013513086A (ja) 2013-04-18
JP2016176953A (ja) 2016-10-06
EP2470904A1 (en) 2012-07-04
CN105004864A (zh) 2015-10-28
WO2011035097A1 (en) 2011-03-24
HK1167889A1 (zh) 2012-12-14
CA2773905A1 (en) 2011-03-24
AU2010295512B2 (en) 2014-12-18
US20190250170A1 (en) 2019-08-15
CN105004864B (zh) 2017-11-03
CN102576012B (zh) 2015-07-15
CN102576012A (zh) 2012-07-11
EP2470904A4 (en) 2013-05-01
HK1212774A1 (zh) 2016-06-17
NZ598741A (en) 2013-07-26
US20130045494A1 (en) 2013-02-21
NZ612673A (en) 2014-10-31
AU2010295512A1 (en) 2012-04-05
JP2015129764A (ja) 2015-07-16

Similar Documents

Publication Publication Date Title
EA201290711A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EA201290629A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EA201490384A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EA201290056A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
EA201290106A1 (ru) Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности
NZ630277A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201290192A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
NZ625423A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2767833A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ605698A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201490105A1 (ru) Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
MX2008010896A (es) Metodo para detectar o diagnosticar una enfermedad o condicion neurodegenerativa.
EA201370063A1 (ru) Фосфолипидом рака
WO2006113529A3 (en) Diagnosis of sepsis
EA201290311A1 (ru) Факторы риска и прогнозирование инфаркта миокарда
EP2813848A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
DE602007013524D1 (de) Erkennung und vorhersage von frühgeburten
WO2008061149A3 (en) Methods and compositions for diagnosis and prognosis of renal artery stenosis
EA201790696A1 (ru) Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности
BR112015014232A2 (pt) lesão renal aguda
TR201900481T4 (tr) Bağışıklık testi için aparat ve kit.
AR074655A1 (es) Metodos para la clasificacion y el diagnostico de escoliosis
NZ605561A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
ATE549417T1 (de) Diagnoseverfahren für osteoarthritis
EA201390294A1 (ru) Способы и композиции для оценки повреждения почек с применением гиалуроновой кислоты