EA201290106A1 - Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности - Google Patents
Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточностиInfo
- Publication number
- EA201290106A1 EA201290106A1 EA201290106A EA201290106A EA201290106A1 EA 201290106 A1 EA201290106 A1 EA 201290106A1 EA 201290106 A EA201290106 A EA 201290106A EA 201290106 A EA201290106 A EA 201290106A EA 201290106 A1 EA201290106 A1 EA 201290106A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- kidney damage
- compositions
- methods
- prediction
- diagnosis
- Prior art date
Links
- 210000003734 kidney Anatomy 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 229940121738 Metalloproteinase-4 inhibitor Drugs 0.000 abstract 1
- 102000012607 Thrombomodulin Human genes 0.000 abstract 1
- 108010079274 Thrombomodulin Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000000090 biomarker Substances 0.000 abstract 1
- 239000000104 diagnostic biomarker Substances 0.000 abstract 1
- 229940099472 immunoglobulin a Drugs 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000000092 prognostic biomarker Substances 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/7452—Thrombomodulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24400009P | 2009-09-18 | 2009-09-18 | |
| US24399509P | 2009-09-18 | 2009-09-18 | |
| US25463609P | 2009-10-23 | 2009-10-23 | |
| PCT/US2010/049234 WO2011035097A1 (en) | 2009-09-18 | 2010-09-17 | Methods and composition for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201290106A1 true EA201290106A1 (ru) | 2012-12-28 |
Family
ID=43759017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201290106A EA201290106A1 (ru) | 2009-09-18 | 2010-09-17 | Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20130045494A1 (https=) |
| EP (2) | EP2470904A4 (https=) |
| JP (3) | JP2013513086A (https=) |
| CN (2) | CN102576012B (https=) |
| AU (2) | AU2010295512B2 (https=) |
| CA (1) | CA2773905A1 (https=) |
| EA (1) | EA201290106A1 (https=) |
| MX (1) | MX2012003168A (https=) |
| NZ (2) | NZ612673A (https=) |
| WO (1) | WO2011035097A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2748605T (pt) * | 2011-08-26 | 2019-05-03 | Astute Medical Inc | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
| US20160147958A1 (en) * | 2013-07-26 | 2016-05-26 | Koninklijke Philips N.V. | Computerization and visualization of clinical rules and definitions for patient monitoring systems |
| GB201501597D0 (en) * | 2015-01-30 | 2015-03-18 | Randox Lab Ltd | Thrombomodulin |
| JP6232689B2 (ja) | 2015-06-25 | 2017-11-22 | 株式会社国際電気通信基礎技術研究所 | 多器官連関システムを基盤とした予測装置、及び予測プログラム |
| US20190033325A1 (en) * | 2016-01-29 | 2019-01-31 | Advanced Telecommunications Research Institute International | Renal function evaluating device, device for predicting onset of kidney disease complications, and phosphorous ingestion amount estimating device |
| CN114594268A (zh) | 2016-03-29 | 2022-06-07 | 无限生物制药公司 | 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法 |
| EP3466446B1 (en) | 2016-03-29 | 2023-12-27 | Karydo Therapeutix, Inc. | Pharmaceutical composition or food composition, and method for assessing effect of active ingredient in vivo |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| JPH0736019B2 (ja) * | 1989-12-27 | 1995-04-19 | 富士薬品工業株式会社 | 新規な抗ヒトトロンボモジュリンモノクローナル抗体によるヒトトロンボモジュリンおよびその分解産物の定量方法 |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| AU1772992A (en) | 1991-04-10 | 1992-11-17 | Biosite Diagnostics Incorporated | Crosstalk inhibitors and their uses |
| JP3290988B2 (ja) | 1991-04-11 | 2002-06-10 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | 多重リガンドを同時検出する新規接合体及び検定法 |
| US5885527A (en) | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6544761B2 (en) * | 1994-12-13 | 2003-04-08 | Human Genome Sciences, Inc. | Human tissue inhibitor of metalloproteinase-4 |
| CN1495258A (zh) * | 1994-12-13 | 2004-05-12 | 人体基因组科学有限公司 | 金属蛋白酶-4的人组织抑制剂 |
| CN1129666C (zh) * | 1994-12-13 | 2003-12-03 | 人体基因组科学有限公司 | 金属蛋白酶-4的人组织抑制剂 |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| WO2001042438A2 (en) * | 1999-12-13 | 2001-06-14 | Regents Of The University Of Minnesota | Leukolysin/mmp25/mt6-mmp |
| AU2002227365A1 (en) * | 2000-12-07 | 2002-06-18 | Chiron Corporation | Endogenous retroviruses up-regulated in prostate cancer |
| WO2003006989A1 (fr) * | 2001-07-12 | 2003-01-23 | Kyowa Medex Co., Ltd. | Procede de quantification de lipoproteines denaturees, reactifs pour la quantification de lipoproteines denaturees, procede de detection de maladies du systeme circulatoire et reactifs pour la detection de maladies du systeme circulatoire |
| CN1972703A (zh) * | 2004-03-30 | 2007-05-30 | 丹麦皇家兽医和农业学院 | 通过阻断和检测蛋白酶抑制剂改进癌症的治疗和癌症治疗效率的预测 |
| US7713693B1 (en) * | 2004-09-01 | 2010-05-11 | University Of Louisiana At Monroe | Human cancer cell specific gene transcript |
| US20060160112A1 (en) * | 2004-12-02 | 2006-07-20 | Erdal Cavusoglu | Tissue inhibitor of metalloproteinase (TIMP) as a marker and predictor of cardiovascular disease and both cardiac and non-cardiac mortality |
| US20090178145A1 (en) * | 2005-05-11 | 2009-07-09 | The Procter & Gamble Company | Methods and targets for identifying compounds for regulating angiogenesis |
| WO2007053610A2 (en) * | 2005-11-01 | 2007-05-10 | The Regents Of The University Of California | Methods of treating atrial fibrillation wtih pirfenidone |
| JP2007163151A (ja) * | 2005-12-09 | 2007-06-28 | Kitasato Gakuen | 対象生物の生理状態を判定する方法 |
| CN101490273A (zh) * | 2006-05-09 | 2009-07-22 | 南卡罗来纳州医科大学研究发展基金会 | 利用蛋白酶和蛋白酶抑制剂血浆分析检测舒张期心力衰竭 |
| MX2008014155A (es) * | 2006-05-09 | 2009-02-25 | Musc Found For Res Dev | Deteccion de insuficiencia cardiaca diastolica por proteasa y determinacion de perfil plasmatico de inhibidor de proteasa. |
| WO2008084331A2 (en) * | 2006-06-21 | 2008-07-17 | Hopitaux Universitaires De Geneve | Biomarkers for renal disorders |
| US8445222B2 (en) * | 2006-07-11 | 2013-05-21 | Musc Foundation For Research Development | Predicting heart failure following myocardial infarction by protease and protease inhibitor profiling |
| GB0617429D0 (en) * | 2006-09-05 | 2006-10-18 | Electrophoretics Ltd | Markers of renal transplant rejection and renal damage |
| WO2008060607A2 (en) * | 2006-11-14 | 2008-05-22 | Biosite Incorporated | Methods and compositions for monitoring and risk prediction in cardiorenal syndrome |
| FR2909180B1 (fr) * | 2006-11-29 | 2009-02-20 | Diagnostica Stago Soc Par Acti | Methode de mesure fonctionnelle de l'activite de la thrombomoduline plasmatique. |
-
2010
- 2010-09-17 US US13/395,114 patent/US20130045494A1/en not_active Abandoned
- 2010-09-17 AU AU2010295512A patent/AU2010295512B2/en not_active Ceased
- 2010-09-17 EP EP10817878.1A patent/EP2470904A4/en not_active Withdrawn
- 2010-09-17 NZ NZ612673A patent/NZ612673A/en not_active IP Right Cessation
- 2010-09-17 EA EA201290106A patent/EA201290106A1/ru unknown
- 2010-09-17 CN CN201080043037.2A patent/CN102576012B/zh not_active Expired - Fee Related
- 2010-09-17 EP EP17196557.7A patent/EP3299821A1/en not_active Withdrawn
- 2010-09-17 CA CA2773905A patent/CA2773905A1/en not_active Abandoned
- 2010-09-17 JP JP2012529920A patent/JP2013513086A/ja active Pending
- 2010-09-17 WO PCT/US2010/049234 patent/WO2011035097A1/en not_active Ceased
- 2010-09-17 CN CN201510401130.0A patent/CN105004864B/zh not_active Expired - Fee Related
- 2010-09-17 MX MX2012003168A patent/MX2012003168A/es active IP Right Grant
- 2010-09-17 NZ NZ598741A patent/NZ598741A/xx not_active IP Right Cessation
-
2015
- 2015-02-25 AU AU2015200953A patent/AU2015200953A1/en not_active Abandoned
- 2015-02-27 JP JP2015038493A patent/JP2015129764A/ja active Pending
-
2016
- 2016-04-21 JP JP2016085091A patent/JP6403712B2/ja not_active Expired - Fee Related
-
2019
- 2019-01-18 US US16/251,407 patent/US20190250170A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN102576012B (zh) | 2015-07-15 |
| JP6403712B2 (ja) | 2018-10-10 |
| CN105004864A (zh) | 2015-10-28 |
| JP2013513086A (ja) | 2013-04-18 |
| JP2015129764A (ja) | 2015-07-16 |
| MX2012003168A (es) | 2012-05-08 |
| EP2470904A4 (en) | 2013-05-01 |
| CN105004864B (zh) | 2017-11-03 |
| EP2470904A1 (en) | 2012-07-04 |
| JP2016176953A (ja) | 2016-10-06 |
| US20190250170A1 (en) | 2019-08-15 |
| HK1167889A1 (zh) | 2012-12-14 |
| WO2011035097A1 (en) | 2011-03-24 |
| NZ598741A (en) | 2013-07-26 |
| US20130045494A1 (en) | 2013-02-21 |
| AU2015200953A1 (en) | 2015-03-12 |
| HK1212774A1 (zh) | 2016-06-17 |
| AU2010295512B2 (en) | 2014-12-18 |
| AU2010295512A1 (en) | 2012-04-05 |
| CN102576012A (zh) | 2012-07-11 |
| NZ612673A (en) | 2014-10-31 |
| CA2773905A1 (en) | 2011-03-24 |
| EP3299821A1 (en) | 2018-03-28 |
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