CN1025590C

CN1025590C - Preparation of injection for anal fistula

Info

Publication number: CN1025590C
Application number: CN 90105504
Authority: CN
Inventors: 邓恺
Original assignee: Individual
Current assignee: Individual
Priority date: 1990-07-20
Filing date: 1990-07-20
Publication date: 1994-08-10
Anticipated expiration: 2005-07-20
Also published as: CN1047806A

Abstract

The present invention belongs to a method for preparing an injection for treating anal fistula, which is prepared from the following Chinese medicines: 20% to 25% of Chinese honeylocust spine, 10% to 15% of pangolin, 10% to 15% of milkvetch root, 5% to 10% of rhizoma coptidis from Sichuan of China, 7% to 12% of centipede, etc. The medicine liquid is obtained by methods of boiling, boiling by back flow at constant temperature, distillating, boiling by adding active carbon, cooling, filtering, precipitating, refiltering, etc. The medicine liquid is added to Tween-80, and phenylmethanol is dissolved in the medicine liquid to regulate the pH value of the medicine liquid; injection water is added until a full quantity; steam sterilization at high temperature is applied to the medicine liquid; then, the medicine liquid is potted, sealed and packaged into boxes.

Description

Preparation of injection for anal fistula

The invention belongs to a kind of preparation method of injection for anal fistula.

Anal fistula disease and each phase internal hemorrhoid disease are a kind of common stubborn diseases, are difficult for radical cure; According to traditional Therapeutic Method, be to adopt operative drainage and seton treatment method, but still can cause the adverse consequences of anal stenosis and anal incontinence accidentally.

The objective of the invention is to bring benefit to the people in order to reduce anal fistula disease and each phase internal hemorrhoid patient's misery.

The present invention adopts Chinese medicine Spina Gleditsiae, Squama Manis, Rhizoma Coptidis, the Radix Astragali, the preparations such as (parches) of centipede worm, and employing is boiled, and methods such as backflow is boiled, distillation, charcoal treatment are prepared from, and are to be used for the treatment of anal fistula and each phase internal hemorrhoid disease.

The method of the present invention's preparation is to adopt Chinese medicine Spina Gleditsiae 20% to 25%, Squama Manis 10% to 15%, add and be placed with in the alembic of 50 to 100 premium on currency, be warming up to 70～90 degree, constant temperature is 20 to 40 minutes then, cooling, add the Radix Astragali 10% to 15% again, Rhizoma Coptidis 5% to 10%, centipede worm (parch) 7% to 12% continues to heat to 80～110 degree, backflow constant temperature 20 to 30 minutes, collect fraction then, receive behind the former medicine, add 0.1% to 0.5% active carbon and reduce phlegm and internal heat former and decolouring was boiled 10 to 30 minutes, carry out cold filtration, precipitation refilters, and then the gained medicinal liquid is added tween 80,0.5% to 1%, benzyl alcohol makes molten, and regulating pH value is 7 to 9, adds to the full amount of water for injection, sterilization is 20 to 40 minutes under 100 to 150 degree steams, carries out fill then, seal, be packaged into box.Technology sees accompanying drawing for details.

The injection that the method for the present invention's preparation is made is to be used for sick and each the phase internal hemorrhoid patient of anal fistula, and each only need of anal fistula patient annotated 1 to 5 milliliter, and general internal hemorrhoid patient only need annotate 0.2 to 0.4 milliliter, and especially big internal hemorrhoid patient infusion is no more than 1 milliliter.

Embodiment:

1. required medicine is differentiated that foreign material are removed in washing, shred standby.

2. the Spina Gleditsiae of getting ready being taken by weighing 100 to 150 grams, Squama Manis 80 to 120 gram adds and is placed with in the alembic of 50～100 premium on currency, be warming up to 80～100 degree, constant temperature 20 to 40 minutes, cooling, add the Radix Astragali 80 to 120 grams, Rhizoma Coptidis 30 to 80 grams, centipede worm (parch) 50 to 90 grams continue to heat up and boil to 80～120 degree, backflow constant temperature 20 to 40 minutes is collected fraction then.

3. receive behind the former medicine, the active carbon of adding 0.1%～0.5% reduces phlegm and internal heat former and decolouring was boiled 10 to 30 minutes, cold filtration precipitates, refilters, and medicinal liquid is added tween 80,0.5%～1%, benzyl alcohol makes molten, and regulating pH value is 7 to 9, adds water for injection to full dose, sterilization is 20 to 40 minutes under 100～150 degree steam, carries out fill then, seals, is packaged into box.

Claims

1, a kind of preparation method that is used for the treatment of the injection of anal fistula and each phase internal hemorrhoid, it is characterized in that: adopt the Chinese medicine preparation, raw material weight is: Spina Gleditsiae 100-150 gram, Squama Manis 80-120 gram, Rhizoma Coptidis 30-80 gram, Prospirolboli joannsi (parch) 50-90 gram, Radix Astragali 80-120 gram, raw material add water boil, distill, add active carbon reduces phlegm and internal heat former and decolouring, boils, cold filtration then, precipitation refilters, in the gained medicinal liquid, add the tween 80 that accounts for medicinal liquid total amount 0.5-1%, the re-adjustment pH value is 7-9, adding distil water is to full dose, sterilization, canned, seal, be packaged into box.

2, the preparation method of injection as claimed in claim 1, it is characterized in that: earlier Spina Gleditsiae and Squama Manis are put into alembic and be warmed up to 80-100 ℃, constant temperature 20-40 minute, the cooling back adds Rhizoma Coptidis, the Radix Astragali, Prospirolboli joannsi (parch) is warmed up to 80-120 ℃, and backflow constant temperature 20-40 minute is collected fraction then.

3, as claim 1,2 described preparation methoies, it is characterized in that: the medical activated carbon of gained fraction adding 0.1-0.5% reduces phlegm and internal heat former and decolours, boiled 10-30 minute; 100-150 ℃ steam sterilization 20-40 minute adopted in sterilization.