CN102552679B - 一种治疗病毒性心肌炎的药剂 - Google Patents
一种治疗病毒性心肌炎的药剂 Download PDFInfo
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Abstract
本发明涉及一种治疗病毒性心肌炎的药剂，它是由下列原料药制成：甘松、苦参、远志、黄芪、茯苓、降香、酸枣仁、麦冬、金银花、杜仲和益母草。本发明所述的治疗病毒性心肌炎的药剂使用天然药物，因此其具有见效快、疗效好、无毒副作用的优点。
Description
技术领域
本发明涉及医药领域，具体地说，涉及一种治疗病毒性心肌炎的药剂。
背景技术
病毒性心肌炎是指由柯萨奇病毒、埃可(ECHO)、脊髓灰质炎、腺病毒40、41，流感病毒感染引起的心肌局限性或弥漫性的急性或慢性炎症病变，属于感染性心肌疾病。病毒作用于心肌的方式是直接侵犯心肌以及心肌内小血管损伤。由免疫机制产生心肌损害在心肌炎的发病中起着重要作用。病毒的直接侵害和免疫反应介导致使心肌细胞损害，使心脏舒缩功能障碍；病变若累及窦房结、房室结、束支等起搏或传导系统，则可引发各种类型的心律失常。此外，本病还可能与硒缺乏及HLA类抗原异常表达有关。由柯萨奇B组病毒感染引起的心肌炎，最终约10％演变为扩张型心肌病。病人常先有发热、全身酸痛、咽痛、倦怠、恶心、呕吐、腹泻等症状，然后出现心悸、胸闷、胸痛或心前区隐痛、头晕、呼吸困难、浮肿，甚至Adams-Stokes综合征；极少数患者出现心力衰竭或心源性休克。
目前，迫切需要一种有效治疗病毒性心肌炎的药物。
发明内容
本发明的目的是提供一种治疗病毒性心肌炎的药剂。
为了实现本发明的目的，本发明提供一种治疗病毒性心肌炎的药剂，它是由下列原料药按重量份计制成：甘松5-10份、苦参10-20份、远志20-30份、黄芪10-20份、茯苓10-20份、降香5-15份、酸枣仁10-30份、麦冬10-20份、金银花5-10份、杜仲10-20和益母草5-10份。
优选地，它是由下列原料药按重量份计制成：甘松8份、苦参15份、远志25份、黄芪15份、茯苓15份、降香10份、酸枣仁20份、麦冬15份、金银花8份、杜仲15和益母草8份。
优选地，所述药物组合物制成片剂、分散片、口含片、散剂或颗粒剂。
本发明所述的治疗病毒性心肌炎的药剂使用天然药物，因此其具有见效快、疗效好、无毒副作用的优点。
具体实施方式
以下通过具体实施方式的描述对本发明作进一步说明，但这并非是对本发明的限制，本领域技术人员根据本发明的基本思想，可以做出各种修改或改进，但是只要不脱离本发明的基本思想，均在本发明的范围之内。
实施例1本发明散剂的制备
取甘松80克、苦参150克、远志250克、黄芪150克、茯苓150克、降香100克、酸枣仁200克、麦冬150克、金银花80克、杜仲150克和益母草80克，粉碎，过100目筛，然后加入蔗糖500克，混匀，装入100袋中即得。
实验例
病例选择120例患者均符合第七版内科学病毒性心肌炎诊断标准，其中男64例，女56例，年龄13～54岁；有上呼吸道感染史75例。120例患者中有发热表现者81例，乏力95例，胸闷、心悸82例，心前区疼痛，面色苍白62例，恶心呕吐39例。血常规白细胞计数为：4.1～15.3x 109/L，其中白细胞增高＞10.0x 109/L 32例，急性期红细胞沉降率升高48例，血清肌酸激酶同工酶升高59例。轻症患者心电图常表现为T波低平或倒置，肢体导联低电压，重者可出现ST段压低甚至心肌梗死样ST段抬高或异常Q波，可出现各种心律失常。
使用实施例1中制得的药物来进行治疗，其中一天3次，每次一袋，治疗1月为一个疗程。病程中复查血、尿常规、血糖、血脂、肝肾功能、心肌酶、电解质及心电图。
疗效判定标准
显效：症状体征基本消失，实验室检查正常，心电图恢复正常，有效：临床症状部分消失，体征及实验室检查有改善，心电图好转；无效：临床症状，体征及各项相关检查无改善。
经过有一个疗程的观察，发现120位患者治疗效果均为显效，并且在整个治疗期间未观察到明显的不良反应。
在治疗一个疗程后每周均对患者进行随访，持续半年，并未发现复发的迹象。
Claims (2)
1.一种治疗病毒性心肌炎的药剂，其特征在于，它是由下列原料药按重量份计制成：甘松8份、苦参15份、远志25份、黄芪15份、茯苓15份、降香10份、酸枣仁20份、麦冬15份、金银花8份、杜仲15和益母草8份。
2.根据权利要求1所述的治疗病毒性心肌炎的药剂，其特征在于，所述药剂为片剂、散剂或颗粒剂。
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| CN104306867A (zh) * | 2014-11-04 | 2015-01-28 | 郝晓臣 | 一种治疗病毒性心肌炎的中药制剂及制备方法 |
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Non-Patent Citations (4)
| Title |
|---|
| 刘虹.古方辨病治疗病毒性心肌炎进展.《医学综述》.2002,第8卷(第6期),366-367. |
| 古方辨病治疗病毒性心肌炎进展;刘虹;《医学综述》;20020630;第8卷(第6期);366-367 * |
| 吴新富等.病毒性心肌炎中医药治疗研究近况.《江西中医学院学报》.2006,第18卷(第3期),68-71. |
| 病毒性心肌炎中医药治疗研究近况;吴新富等;《江西中医学院学报》;20060630;第18卷(第3期);68-71 * |
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