CN102552650A - Skin antibacterial agent and preparation method thereof - Google Patents
Skin antibacterial agent and preparation method thereof Download PDFInfo
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- CN102552650A CN102552650A CN2012100396851A CN201210039685A CN102552650A CN 102552650 A CN102552650 A CN 102552650A CN 2012100396851 A CN2012100396851 A CN 2012100396851A CN 201210039685 A CN201210039685 A CN 201210039685A CN 102552650 A CN102552650 A CN 102552650A
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- 238000002360 preparation method Methods 0.000 title abstract description 7
- 239000003242 anti bacterial agent Substances 0.000 title abstract 7
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 161
- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 28
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000012153 distilled water Substances 0.000 claims abstract description 23
- 238000006555 catalytic reaction Methods 0.000 claims abstract description 16
- 239000011259 mixed solution Substances 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 10
- 230000008569 process Effects 0.000 claims abstract description 5
- 241000628997 Flos Species 0.000 claims description 26
- 241000218628 Ginkgo Species 0.000 claims description 26
- 102000004190 Enzymes Human genes 0.000 claims description 25
- 108090000790 Enzymes Proteins 0.000 claims description 25
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 25
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 25
- 230000004071 biological effect Effects 0.000 claims description 25
- 239000001963 growth medium Substances 0.000 claims description 25
- 230000002070 germicidal effect Effects 0.000 claims description 22
- 102000004142 Trypsin Human genes 0.000 claims description 20
- 108090000631 Trypsin Proteins 0.000 claims description 20
- 239000012588 trypsin Substances 0.000 claims description 20
- 239000000243 solution Substances 0.000 claims description 10
- 239000003054 catalyst Substances 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 6
- 241001013248 Eulepidotis folium Species 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 102100032491 Serine protease 1 Human genes 0.000 claims description 4
- 101710151387 Serine protease 1 Proteins 0.000 claims description 4
- 101710119665 Trypsin-1 Proteins 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 3
- 244000144987 brood Species 0.000 claims description 3
- 238000012544 monitoring process Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 abstract description 6
- 206010052428 Wound Diseases 0.000 abstract description 5
- 208000027418 Wounds and injury Diseases 0.000 abstract description 5
- 238000001228 spectrum Methods 0.000 abstract description 4
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 4
- 230000035876 healing Effects 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 3
- 244000291564 Allium cepa Species 0.000 abstract 2
- 235000002732 Allium cepa var. cepa Nutrition 0.000 abstract 2
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 2
- 240000006891 Artemisia vulgaris Species 0.000 abstract 2
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 2
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 2
- 244000194101 Ginkgo biloba Species 0.000 abstract 2
- 244000234609 Portulaca oleracea Species 0.000 abstract 2
- 235000001855 Portulaca oleracea Nutrition 0.000 abstract 2
- 244000046146 Pueraria lobata Species 0.000 abstract 2
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 2
- 244000061458 Solanum melongena Species 0.000 abstract 2
- 235000002597 Solanum melongena Nutrition 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 description 7
- 230000003115 biocidal effect Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000000855 fungicidal effect Effects 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 229910000497 Amalgam Inorganic materials 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical group Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 101710119666 Trypsin-2 Proteins 0.000 description 1
- 102100034392 Trypsin-2 Human genes 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a skin antibacterial agent and a preparation method thereof. The skin antibacterial agent comprises components such as ginkgo leaf juice, white chrysanthemum juice, eggplant root juice, kudzuvine root juice, mugwort leaf juice, portulaca oleracea juice, fistular onion stalk juice, distilled water and the like. The preparation method for the skin antibacterial agent comprises the following steps of: mixing the ginkgo leaf juice, the white chrysanthemum juice, the eggplant root juice, the kudzuvine root juice, the mugwort leaf juice, the portulaca oleracea juice, the fistular onion stalk juice and the distilled water, stirring uniformly, heating for 6 to 8 hours at the temperature of 65 to 70 DEG C, adding an auxiliary raw material into the mixed solution to ensure that the mixed solution is subjected to catalytic reaction, and thus obtaining the skin antibacterial agent, wherein a biological monitor in a catalytic reaction device is used for automatically tracking and testing in the process of the catalytic reaction. The invention has the advantages that: the skin antibacterial agent has wide sterilization spectrum, is low in effective concentration, quick in response and stable in performance, greatly improves healing degree of wounds and relieves pain of patients in the process of changing and applying medicines; and in addition, the preparation method for the skin antibacterial agent is simple and convenient to operate.
Description
[technical field]
The present invention relates to antibiotic articles for use and preparation method thereof, specifically a kind of germicide for skin and preparation method thereof.
[background technology]
Along with the raising day by day of international and domestic medical and health sterilization level, and constantly the mentioning of people's living standard, people press for the health that can safeguard the mankind itself, the not contaminated disinfecting, antimicrobial product of the environment that can protect nature again.
At present; The germicide for skin that people generally use is chloride class, oxidation class, quaternary ammonium salt, though these antibacterial possess antibiotic and sterilizing effect to a certain degree, its toxicity is bigger; When people when using these antibacterial; But injured the health of self unawares, simultaneously, these antibacterial have also caused pollution to the environment of the Nature.In addition, the fungicidal spectrum of this antibacterial is narrow, and valid density is high, and speed of action is slow, and stability is also relatively poor, can not satisfy people's demand.
[summary of the invention]
The object of the invention is exactly to solve above-mentioned deficiency, and provides a kind of fungicidal spectrum wide, free from environmental pollution and to the germicide for skin of human body safety, and the method for preparing this germicide for skin.
The object of the invention can be realized through following technical scheme:
A kind of germicide for skin comprises following components in part by weight:
Folium Ginkgo juice 14-18%, Flos Chrysanthemi juice 3-6%, white Radix Solani Melongenae juice 18-24%, Radix Puerariae juice 1.5-3.5%, Folium Artemisiae Argyi juice 10-19%, juice of Herba Portulacae 16-19%, very light blue juice 14-16%, distilled water 8-11%, auxiliary material 5-10%.
Said auxiliary material is bean ferment culture medium, trypsin, biological activity protein enzyme, and the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium 3-5%, trypsin 1-2%, biological activity protein enzyme 1.5-2.5%.
The percentage by weight of said Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water, bean ferment culture medium, trypsin, biological activity protein enzyme is: Folium Ginkgo juice 15%, Flos Chrysanthemi juice 4%, white Radix Solani Melongenae juice 19%, Radix Puerariae juice 2.5%, Folium Artemisiae Argyi juice 12%, juice of Herba Portulacae 17%, very light blue juice 15%, distilled water 9%, bean ferment culture medium 4%, trypsin 1%, biological activity protein enzyme 1.5%.
A kind of method for preparing of germicide for skin may further comprise the steps:
1) with Folium Ginkgo, Flos Chrysanthemi, white Radix Solani Melongenae, Radix Puerariae, Folium Artemisiae Argyi, Herba Portulacae, very light blue clean respectively after; Pulverize with pulverizer; Add distilled water and decoct, extract concentrated solution separately, i.e. Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice;
2) Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water are pressed the percentage by weight mixing of Folium Ginkgo juice 14-18%, Flos Chrysanthemi juice 3-6%, white Radix Solani Melongenae juice 18-24%, Radix Puerariae juice 1.5-3.5%, Folium Artemisiae Argyi juice 10-19%, juice of Herba Portulacae 16-19%, very light blue juice 14-16%, distilled water 8-11%, and stirred;
3) mixed solution was heated 6-8 hour, temperature is 65-70 ℃;
4) cooling is after 1 hour; In mixed solution, add bean ferment culture medium, trypsin, biological activity protein enzyme; Make it in catalyst reaction device, carry out catalytic reaction, the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium 3-5%, trypsin 1-2%, biological activity protein enzyme 1.5-2.5%;
5) after catalytic reaction finishes, with solution left standstill 1 hour, promptly get germicide for skin again.
In the said catalytic reaction process, undertaken detecting from motion tracking by the biological monitoring appearance in the catalyst reaction device, the material that utilizes of its examination criteria is stearothermophilus brood cell bacterium bacterium sheet.
The present invention compares with prior art, and its beneficial effect is: because the raw material of this germicide for skin is extracted from natural plants, and form through the formulation of uniqueness; Thereby it is not only tasteless to human non-toxic; Without any side effects, and do not destroy natural environment, even can purified water source; Further balance ecological environment promotes environmental protection; In addition, germicide for skin of the present invention has very strong biocidal efficacies, and its fungicidal spectrum is wide, and valid density is low, instant effect, and stable in properties improved the healing degree of wound greatly, alleviated the change dressings misery of medicine-feeding of patient; Not only processing technology is simple for germicide for skin method for preparing of the present invention, and is easy to operate, and cost is low.
[specific embodiment]
Below in conjunction with embodiment the present invention is described further:
Embodiment 1
1) with Folium Ginkgo, Flos Chrysanthemi, white Radix Solani Melongenae, Radix Puerariae, Folium Artemisiae Argyi, Herba Portulacae, very light blue clean respectively after; Pulverize with pulverizer; Add distilled water and decoct, extract concentrated solution separately, i.e. Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice;
2) Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water are pressed the percentage by weight mixing of Folium Ginkgo juice 14%, Flos Chrysanthemi juice 3%, white Radix Solani Melongenae juice 22%, Radix Puerariae juice 1.5%, Folium Artemisiae Argyi juice 16%, juice of Herba Portulacae 16%, very light blue juice 14%, distilled water 8%, and stirred;
3) mixed solution was heated 6 hours, temperature is 65-70 ℃;
4) cooling is after 1 hour; In mixed solution, add bean ferment culture medium, trypsin, biological activity protein enzyme; Make it in catalyst reaction device, carry out catalytic reaction, the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium 3%, trypsin 1%, biological activity protein enzyme 1.5%;
5) after catalytic reaction finishes, with solution left standstill 1 hour, promptly get germicide for skin again.
Embodiment 2
1) with Folium Ginkgo, Flos Chrysanthemi, white Radix Solani Melongenae, Radix Puerariae, Folium Artemisiae Argyi, Herba Portulacae, very light blue clean respectively after; Pulverize with pulverizer; Add distilled water and decoct, extract concentrated solution separately, i.e. Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice;
2) Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water are pressed the percentage by weight mixing of Folium Ginkgo juice 15%, Flos Chrysanthemi juice 4%, white Radix Solani Melongenae juice 19%, Radix Puerariae juice 2.5%, Folium Artemisiae Argyi juice 12%, juice of Herba Portulacae 17%, very light blue juice 15%, distilled water 9%, and stirred;
3) mixed solution was heated 7 hours, temperature is 65-70 ℃;
4) cooling is after 1 hour; In mixed solution, add bean ferment culture medium, trypsin, biological activity protein enzyme; Make it in catalyst reaction device, carry out catalytic reaction, the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium %, trypsin 1%, biological activity protein enzyme 1.5%;
5) after catalytic reaction finishes, with solution left standstill 1 hour, promptly get germicide for skin again.
Embodiment 3
1) with Folium Ginkgo, Flos Chrysanthemi, white Radix Solani Melongenae, Radix Puerariae, Folium Artemisiae Argyi, Herba Portulacae, very light blue clean respectively after; Pulverize with pulverizer; Add distilled water and decoct, extract concentrated solution separately, i.e. Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice;
2) Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water are pressed the percentage by weight mixing of Folium Ginkgo juice 16%, Flos Chrysanthemi juice 4%, white Radix Solani Melongenae juice 18%, Radix Puerariae juice 1.5%, Folium Artemisiae Argyi juice 10%, juice of Herba Portulacae 18%, very light blue juice 16%, distilled water 10%, and stirred;
3) mixed solution was heated 8 hours, temperature is 65-70 ℃;
4) cooling is after 1 hour; In mixed solution, add bean ferment culture medium, trypsin, biological activity protein enzyme; Make it in catalyst reaction device, carry out catalytic reaction, the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium 3%, trypsin 2%, biological activity protein enzyme 1.5%;
5) after catalytic reaction finishes, with solution left standstill 1 hour, promptly get germicide for skin again.
Among the present invention, in catalytic reaction process, be that the biological monitoring appearance carries out detecting from motion tracking by the auxiliary facilities in the catalyst reaction device, the material that utilizes of its examination criteria is the stearothermophilus brood cell bacterium bacterium sheet that has resistance most.
Among the present invention, the antibacterial base of said germicide for skin reason is that with the difference of traditional antibacterial what it adopted is the nature sterilization, promptly follows natural science applied biological death rule fully and reaches the effect of sterilization.Its sterilizing mechanisms is: because its prescription is the raw material that from natural plants, extracts; And form through the prepared of uniqueness; Therefore itself be exactly the nature body, contain the effective active matter of unique mixing phage in the amalgam of its prescription, these effective active organisms are in case contact with the detrimental microorganisms object; Will stick on the harmful microorganism body; Make the harmful microorganism body cannot move, make it can not be in free state, thus this stick to the Fungicidal substance that the sp act organism on the harmful microorganism body forms the adhesion total blockage harmful microbe respiration channel; Make it to have lost breathing kinetic energy, finally reach the effect of natural death.
Germicide for skin of the present invention is a kind of biological agent, has extremely strong biocidal efficacies, and various materials are not all had corrosion function, and it uses the effusive waste water in back, gets in the river course, can also purified water source, keep the ecological balance of water quality, and promote environmental protection.Especially operate on or the wound infection severe patient for burn, extensive wound; In case use this antibacterial; The pathogenic bacteria that wound face is infected is dead rapidly, thereby has improved the healing degree of wound greatly, not only make patient can be from crisis the degree of safety mistake; And patient is alleviated greatly change dressings the misery of medicine-feeding, be the real bodyguard who protects the health.
Claims (5)
1. germicide for skin; It is characterized in that, comprise following components in part by weight: Folium Ginkgo juice 14-18%, Flos Chrysanthemi juice 3-6%, white Radix Solani Melongenae juice 18-24%, Radix Puerariae juice 1.5-3.5%, Folium Artemisiae Argyi juice 10-19%, juice of Herba Portulacae 16-19%, very light blue juice 14-16%, distilled water 8-11%, auxiliary material 5-10%.
2. germicide for skin as claimed in claim 1; It is characterized in that: said auxiliary material is bean ferment culture medium, trypsin, biological activity protein enzyme, and the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium 3-5%, trypsin 1-2%, biological activity protein enzyme 1.5-2.5%.
3. according to claim 1 or claim 2 germicide for skin, it is characterized in that: the percentage by weight of said Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water, bean ferment culture medium, trypsin, biological activity protein enzyme is: Folium Ginkgo juice 15%, Flos Chrysanthemi juice 4%, white Radix Solani Melongenae juice 19%, Radix Puerariae juice 2.5%, Folium Artemisiae Argyi juice 12%, juice of Herba Portulacae 17%, very light blue juice 15%, distilled water 9%, bean ferment culture medium 4%, trypsin 1%, biological activity protein enzyme 1.5%.
4. the method for preparing of a germicide for skin is characterized in that, may further comprise the steps:
1) with Folium Ginkgo, Flos Chrysanthemi, white Radix Solani Melongenae, Radix Puerariae, Folium Artemisiae Argyi, Herba Portulacae, very light blue clean respectively after; Pulverize with pulverizer; Add distilled water and decoct, extract concentrated solution separately, i.e. Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice;
2) Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water are pressed the percentage by weight mixing of Folium Ginkgo juice 14-18%, Flos Chrysanthemi juice 3-6%, white Radix Solani Melongenae juice 18-24%, Radix Puerariae juice 1.5-3.5%, Folium Artemisiae Argyi juice 10-19%, juice of Herba Portulacae 16-19%, very light blue juice 14-16%, distilled water 8-11%, and stirred;
3) mixed solution was heated 6-8 hour, temperature is 65-70 ℃;
4) cooling is after 1 hour; In mixed solution, add bean ferment culture medium, trypsin, biological activity protein enzyme; Make it in catalyst reaction device, carry out catalytic reaction, the percentage by weight of said bean ferment culture medium, trypsin, biological activity protein enzyme is: bean ferment culture medium 3-5%, trypsin 1-2%, biological activity protein enzyme 1.5-2.5%;
5) after catalytic reaction finishes, with solution left standstill 1 hour, promptly get germicide for skin again.
5. the method for preparing of germicide for skin as claimed in claim 4 is characterized in that: in the said catalytic reaction process, undertaken detecting from motion tracking by the biological monitoring appearance in the catalyst reaction device, the material that utilizes of its examination criteria is stearothermophilus brood cell bacterium bacterium sheet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100396851A CN102552650A (en) | 2012-02-21 | 2012-02-21 | Skin antibacterial agent and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100396851A CN102552650A (en) | 2012-02-21 | 2012-02-21 | Skin antibacterial agent and preparation method thereof |
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| CN102552650A true CN102552650A (en) | 2012-07-11 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251779A (en) * | 2013-05-22 | 2013-08-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine ointment specially used for treating swine frostbite |
| CN106178078A (en) * | 2016-07-14 | 2016-12-07 | 腾科宝迪（厦门）生物科技有限公司 | Single use Sterilized application and preparation method thereof |
-
2012
- 2012-02-21 CN CN2012100396851A patent/CN102552650A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251779A (en) * | 2013-05-22 | 2013-08-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine ointment specially used for treating swine frostbite |
| CN103251779B (en) * | 2013-05-22 | 2014-12-10 | 山东新希望六和集团有限公司 | Traditional Chinese medicine ointment specially used for treating swine frostbite |
| CN106178078A (en) * | 2016-07-14 | 2016-12-07 | 腾科宝迪（厦门）生物科技有限公司 | Single use Sterilized application and preparation method thereof |
| CN106178078B (en) * | 2016-07-14 | 2017-10-20 | 腾科宝迪（厦门）生物科技有限公司 | Disposable Sterilized application and preparation method thereof |
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Application publication date: 20120711 |