CN102550836B - Animal nutrition additive trace element is combined bag and its preparation method and application - Google Patents
Animal nutrition additive trace element is combined bag and its preparation method and application Download PDFInfo
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- CN102550836B CN102550836B CN201210016114.6A CN201210016114A CN102550836B CN 102550836 B CN102550836 B CN 102550836B CN 201210016114 A CN201210016114 A CN 201210016114A CN 102550836 B CN102550836 B CN 102550836B
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- China
- Prior art keywords
- trace element
- compound
- bag
- glycine
- zinc
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- 239000011573 trace mineral Substances 0.000 title claims abstract description 257
- 235000013619 trace mineral Nutrition 0.000 title claims abstract description 257
- 238000002360 preparation method Methods 0.000 title claims abstract description 35
- 239000000654 additive Substances 0.000 title claims abstract description 33
- 230000000996 additive effect Effects 0.000 title claims abstract description 33
- 235000019728 animal nutrition Nutrition 0.000 title claims abstract description 31
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims abstract description 184
- 150000001875 compounds Chemical class 0.000 claims abstract description 149
- 239000004471 Glycine Substances 0.000 claims abstract description 92
- 241001465754 Metazoa Species 0.000 claims abstract description 72
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 56
- 229910052802 copper Inorganic materials 0.000 claims abstract description 56
- 239000010949 copper Substances 0.000 claims abstract description 56
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 49
- 150000001447 alkali salts Chemical class 0.000 claims abstract description 49
- 239000011701 zinc Substances 0.000 claims abstract description 49
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 49
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims abstract description 41
- 229910052748 manganese Inorganic materials 0.000 claims abstract description 41
- 239000011572 manganese Substances 0.000 claims abstract description 41
- 238000006243 chemical reaction Methods 0.000 claims abstract description 23
- 235000019730 animal feed additive Nutrition 0.000 claims abstract description 21
- 229940082569 selenite Drugs 0.000 claims abstract description 21
- MCAHWIHFGHIESP-UHFFFAOYSA-L selenite(2-) Chemical compound [O-][Se]([O-])=O MCAHWIHFGHIESP-UHFFFAOYSA-L 0.000 claims abstract description 21
- 238000001035 drying Methods 0.000 claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000003513 alkali Substances 0.000 claims abstract description 14
- 239000000725 suspension Substances 0.000 claims abstract description 13
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims abstract description 12
- 238000007664 blowing Methods 0.000 claims abstract description 12
- XTEGARKTQYYJKE-UHFFFAOYSA-M Chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 claims abstract description 10
- 230000033228 biological regulation Effects 0.000 claims abstract description 10
- 229940071566 zinc glycinate Drugs 0.000 claims abstract description 10
- UOXSXMSTSYWNMH-UHFFFAOYSA-L zinc;2-aminoacetate Chemical compound [Zn+2].NCC([O-])=O.NCC([O-])=O UOXSXMSTSYWNMH-UHFFFAOYSA-L 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 8
- VVYPIVJZLVJPGU-UHFFFAOYSA-L copper;2-aminoacetate Chemical compound [Cu+2].NCC([O-])=O.NCC([O-])=O VVYPIVJZLVJPGU-UHFFFAOYSA-L 0.000 claims abstract description 5
- 229940011405 cupric glycinate Drugs 0.000 claims abstract description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 56
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 47
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 46
- 229910052804 chromium Inorganic materials 0.000 claims description 46
- 239000011651 chromium Substances 0.000 claims description 46
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 32
- 229910017052 cobalt Inorganic materials 0.000 claims description 31
- 239000010941 cobalt Substances 0.000 claims description 31
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims description 31
- 239000011669 selenium Substances 0.000 claims description 28
- 229910052711 selenium Inorganic materials 0.000 claims description 27
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 26
- 239000000203 mixture Substances 0.000 claims description 26
- 229910052759 nickel Inorganic materials 0.000 claims description 23
- 229910052732 germanium Inorganic materials 0.000 claims description 17
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 claims description 17
- 229910052757 nitrogen Inorganic materials 0.000 claims description 16
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims description 16
- 239000007921 spray Substances 0.000 claims description 13
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 claims description 11
- 229910052901 montmorillonite Inorganic materials 0.000 claims description 11
- 239000000843 powder Substances 0.000 claims description 10
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 10
- 229910000368 zinc sulfate Inorganic materials 0.000 claims description 10
- 229960001763 zinc sulfate Drugs 0.000 claims description 10
- IXONOEXDSRFORV-UHFFFAOYSA-N 2-aminoacetic acid;cobalt Chemical compound [Co].NCC(O)=O.NCC(O)=O IXONOEXDSRFORV-UHFFFAOYSA-N 0.000 claims description 9
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 9
- 239000011592 zinc chloride Substances 0.000 claims description 8
- 235000005074 zinc chloride Nutrition 0.000 claims description 8
- 241000282849 Ruminantia Species 0.000 claims description 7
- SKQUUKNCBWILCD-UHFFFAOYSA-J dicopper;chloride;trihydroxide Chemical compound [OH-].[OH-].[OH-].[Cl-].[Cu+2].[Cu+2] SKQUUKNCBWILCD-UHFFFAOYSA-J 0.000 claims description 7
- IEOJTQSWHLGOQI-UHFFFAOYSA-L 2-aminoacetate;nickel(2+) Chemical compound [Ni+2].NCC([O-])=O.NCC([O-])=O IEOJTQSWHLGOQI-UHFFFAOYSA-L 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 6
- 239000010433 feldspar Substances 0.000 claims description 6
- 229910052742 iron Inorganic materials 0.000 claims description 6
- 229910000008 nickel(II) carbonate Inorganic materials 0.000 claims description 6
- ZULUUIKRFGGGTL-UHFFFAOYSA-L nickel(ii) carbonate Chemical compound [Ni+2].[O-]C([O-])=O ZULUUIKRFGGGTL-UHFFFAOYSA-L 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- ZAQMFLLRGYSTTK-UHFFFAOYSA-N [Ge].NCC(=O)O Chemical compound [Ge].NCC(=O)O ZAQMFLLRGYSTTK-UHFFFAOYSA-N 0.000 claims description 5
- 239000012670 alkaline solution Substances 0.000 claims description 5
- 239000011575 calcium Substances 0.000 claims description 5
- LGQLOGILCSXPEA-UHFFFAOYSA-L nickel sulfate Chemical compound [Ni+2].[O-]S([O-])(=O)=O LGQLOGILCSXPEA-UHFFFAOYSA-L 0.000 claims description 5
- 229910000363 nickel(II) sulfate Inorganic materials 0.000 claims description 5
- 238000011017 operating method Methods 0.000 claims description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 4
- 229910052791 calcium Inorganic materials 0.000 claims description 4
- 229940116318 copper carbonate Drugs 0.000 claims description 4
- 229910000365 copper sulfate Inorganic materials 0.000 claims description 4
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 4
- GEZOTWYUIKXWOA-UHFFFAOYSA-L copper;carbonate Chemical compound [Cu+2].[O-]C([O-])=O GEZOTWYUIKXWOA-UHFFFAOYSA-L 0.000 claims description 4
- 239000011790 ferrous sulphate Substances 0.000 claims description 4
- 235000003891 ferrous sulphate Nutrition 0.000 claims description 4
- YBMRDBCBODYGJE-UHFFFAOYSA-N germanium oxide Inorganic materials O=[Ge]=O YBMRDBCBODYGJE-UHFFFAOYSA-N 0.000 claims description 4
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 claims description 4
- 229910000359 iron(II) sulfate Inorganic materials 0.000 claims description 4
- 229940099596 manganese sulfate Drugs 0.000 claims description 4
- 239000011702 manganese sulphate Substances 0.000 claims description 4
- 235000007079 manganese sulphate Nutrition 0.000 claims description 4
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 3
- 229910021380 Manganese Chloride Inorganic materials 0.000 claims description 3
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 claims description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 229910021536 Zeolite Inorganic materials 0.000 claims description 3
- 229910021446 cobalt carbonate Inorganic materials 0.000 claims description 3
- ZOTKGJBKKKVBJZ-UHFFFAOYSA-L cobalt(2+);carbonate Chemical compound [Co+2].[O-]C([O-])=O ZOTKGJBKKKVBJZ-UHFFFAOYSA-L 0.000 claims description 3
- HIYNGBUQYVBFLA-UHFFFAOYSA-D cobalt(2+);dicarbonate;hexahydroxide Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Co+2].[Co+2].[Co+2].[Co+2].[Co+2].[O-]C([O-])=O.[O-]C([O-])=O HIYNGBUQYVBFLA-UHFFFAOYSA-D 0.000 claims description 3
- 229910000001 cobalt(II) carbonate Inorganic materials 0.000 claims description 3
- ORTQZVOHEJQUHG-UHFFFAOYSA-L copper(II) chloride Chemical compound Cl[Cu]Cl ORTQZVOHEJQUHG-UHFFFAOYSA-L 0.000 claims description 3
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 3
- 239000011565 manganese chloride Substances 0.000 claims description 3
- 235000002867 manganese chloride Nutrition 0.000 claims description 3
- UOURRHZRLGCVDA-UHFFFAOYSA-D pentazinc;dicarbonate;hexahydroxide Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Zn+2].[Zn+2].[Zn+2].[Zn+2].[Zn+2].[O-]C([O-])=O.[O-]C([O-])=O UOURRHZRLGCVDA-UHFFFAOYSA-D 0.000 claims description 3
- LITQZINTSYBKIU-UHFFFAOYSA-F tetracopper;hexahydroxide;sulfate Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Cu+2].[Cu+2].[Cu+2].[Cu+2].[O-]S([O-])(=O)=O LITQZINTSYBKIU-UHFFFAOYSA-F 0.000 claims description 3
- 238000010792 warming Methods 0.000 claims description 3
- 239000010457 zeolite Substances 0.000 claims description 3
- 239000011787 zinc oxide Substances 0.000 claims description 3
- 229910021503 Cobalt(II) hydroxide Inorganic materials 0.000 claims description 2
- QPLDLSVMHZLSFG-UHFFFAOYSA-N Copper oxide Chemical compound [Cu]=O QPLDLSVMHZLSFG-UHFFFAOYSA-N 0.000 claims description 2
- 239000005751 Copper oxide Substances 0.000 claims description 2
- 239000004277 Ferrous carbonate Substances 0.000 claims description 2
- 229910000428 cobalt oxide Inorganic materials 0.000 claims description 2
- KTVIXTQDYHMGHF-UHFFFAOYSA-L cobalt(2+) sulfate Chemical compound [Co+2].[O-]S([O-])(=O)=O KTVIXTQDYHMGHF-UHFFFAOYSA-L 0.000 claims description 2
- ASKVAEGIVYSGNY-UHFFFAOYSA-L cobalt(ii) hydroxide Chemical compound [OH-].[OH-].[Co+2] ASKVAEGIVYSGNY-UHFFFAOYSA-L 0.000 claims description 2
- IVMYJDGYRUAWML-UHFFFAOYSA-N cobalt(ii) oxide Chemical compound [Co]=O IVMYJDGYRUAWML-UHFFFAOYSA-N 0.000 claims description 2
- 229910000431 copper oxide Inorganic materials 0.000 claims description 2
- FNIHDXPFFIOGKL-UHFFFAOYSA-N disodium;dioxido(oxo)germane Chemical compound [Na+].[Na+].[O-][Ge]([O-])=O FNIHDXPFFIOGKL-UHFFFAOYSA-N 0.000 claims description 2
- 235000019268 ferrous carbonate Nutrition 0.000 claims description 2
- RAQDACVRFCEPDA-UHFFFAOYSA-L ferrous carbonate Chemical compound [Fe+2].[O-]C([O-])=O RAQDACVRFCEPDA-UHFFFAOYSA-L 0.000 claims description 2
- 229960004652 ferrous carbonate Drugs 0.000 claims description 2
- 229960002089 ferrous chloride Drugs 0.000 claims description 2
- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 claims description 2
- 229910000015 iron(II) carbonate Inorganic materials 0.000 claims description 2
- IPJKJLXEVHOKSE-UHFFFAOYSA-L manganese dihydroxide Chemical compound [OH-].[OH-].[Mn+2] IPJKJLXEVHOKSE-UHFFFAOYSA-L 0.000 claims description 2
- PPNAOCWZXJOHFK-UHFFFAOYSA-N manganese(2+);oxygen(2-) Chemical compound [O-2].[Mn+2] PPNAOCWZXJOHFK-UHFFFAOYSA-N 0.000 claims description 2
- VASIZKWUTCETSD-UHFFFAOYSA-N manganese(II) oxide Inorganic materials [Mn]=O VASIZKWUTCETSD-UHFFFAOYSA-N 0.000 claims description 2
- QMMRZOWCJAIUJA-UHFFFAOYSA-L nickel dichloride Chemical compound Cl[Ni]Cl QMMRZOWCJAIUJA-UHFFFAOYSA-L 0.000 claims description 2
- 229910000480 nickel oxide Inorganic materials 0.000 claims description 2
- BFDHFSHZJLFAMC-UHFFFAOYSA-L nickel(ii) hydroxide Chemical compound [OH-].[OH-].[Ni+2] BFDHFSHZJLFAMC-UHFFFAOYSA-L 0.000 claims description 2
- PVADDRMAFCOOPC-UHFFFAOYSA-N oxogermanium Chemical compound [Ge]=O PVADDRMAFCOOPC-UHFFFAOYSA-N 0.000 claims description 2
- GNRSAWUEBMWBQH-UHFFFAOYSA-N oxonickel Chemical compound [Ni]=O GNRSAWUEBMWBQH-UHFFFAOYSA-N 0.000 claims description 2
- 229960001939 zinc chloride Drugs 0.000 claims description 2
- UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 claims description 2
- 229910021511 zinc hydroxide Inorganic materials 0.000 claims description 2
- 229940007718 zinc hydroxide Drugs 0.000 claims description 2
- GVPFVAHMJGGAJG-UHFFFAOYSA-L cobalt dichloride Chemical compound [Cl-].[Cl-].[Co+2] GVPFVAHMJGGAJG-UHFFFAOYSA-L 0.000 claims 1
- 229940097267 cobaltous chloride Drugs 0.000 claims 1
- PTVDYARBVCBHSL-UHFFFAOYSA-N copper;hydrate Chemical compound O.[Cu] PTVDYARBVCBHSL-UHFFFAOYSA-N 0.000 claims 1
- 229960001781 ferrous sulfate Drugs 0.000 claims 1
- 229960001296 zinc oxide Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 22
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- 238000007086 side reaction Methods 0.000 abstract description 3
- 238000012360 testing method Methods 0.000 description 65
- 241000282898 Sus scrofa Species 0.000 description 29
- 229940091258 selenium supplement Drugs 0.000 description 26
- 235000014590 basal diet Nutrition 0.000 description 20
- 238000005516 engineering process Methods 0.000 description 19
- 239000000463 material Substances 0.000 description 19
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 description 18
- 239000011781 sodium selenite Substances 0.000 description 18
- 235000015921 sodium selenite Nutrition 0.000 description 18
- 229960001471 sodium selenite Drugs 0.000 description 18
- 230000000694 effects Effects 0.000 description 16
- 230000002354 daily effect Effects 0.000 description 15
- 241000282887 Suidae Species 0.000 description 14
- 235000013601 eggs Nutrition 0.000 description 13
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 12
- 239000003674 animal food additive Substances 0.000 description 11
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- 102000004190 Enzymes Human genes 0.000 description 7
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- 235000001014 amino acid Nutrition 0.000 description 5
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Abstract
The invention discloses the compound bag of a kind of Animal nutrition additive trace element and preparation thereof and application, this compound bag is mainly made up of the many ore deposits of compound glycine, selenite and trace element basic salt, and the compound many ore deposits of glycine comprise cupric glycinate, glycine ferrous, zinc glycinate, Mn-Gly etc.；Trace element basic salt comprises at least one in alkali formula chlorate, subcarbonate or the subsulfate that trace copper, zinc, manganese etc. are corresponding.The preparation method of the present invention comprises the following steps: is mixed with inorganic microelement compound by raw material glycine and is added to the water, heat up after regulation pH value, it is sufficiently stirred for blowing after reaction completes, other raw materials are added again in product, making homodisperse suspension, last drying is pelletized and is obtained the compound bag of trace element.The trace element of the present invention is compound can be used as animal feed additive, has the advantages such as technique simplifies, biological value is high, addition is low, growth promoting effect is obvious, animal side reaction is few.
Description
Technical field
The present invention relates to animal feed additive field, particularly relate to a kind of compound animal fodder additive and preparation method thereof and
Application.
Background technology
Along with raising and the development of aquaculture of people's living standard, glycine, as feedstuff aminoacid, is widely used in
Add pig starter feed, boar food, broiler fodder, prawn feed and eel feed etc..Glycine is used as animal feed additive
Have the following characteristics that and can be used for producing albumen feedstuff；Can be used as the phagostimulant (attractant) in feed additive, improve animal and adopt
Appetite；Bacillus subtilis and colibacillary breeding can be suppressed, play important antisepsis, reduce piglet and cause because daily ration goes mouldy
Diarrhea rate.Therefore, animal diets adds glycine and can improve efficiency of feed utilization to greatest extent.
Trace copper can effectively participate in the pigment of the formation of the cellular oxidation of body, bone and connective tissue, keratinization and tissue and sink
And the important physiological process such as spinal cord myelin formation, and keep normal cardiac function to have important function body.Copper is also
The required component of some enzyme systems, especially relevant with cellular oxidation metalloenzyme, directly participate in organism metabolism.Copper and the suction of ferrum
Receive closely related with function, the synthesis of the homergy of ferrum element, beneficially hemoglobin and erythrocytic maturation can be maintained；Also
Can be by promoting that hypothalamus secretion luteinising hormone-releasing hormo participates in the breeding activity of body.
Trace elements iron is one of essential trace element of animal, is the important component part of hemoglobin.Ferrum is present in muscle
In the erythrocyte of supply oxygen, or many enzymes and the composition of immune system compound, animal absorb from food needed for big portion
Divide ferrum, and carefully control iron content.Ferrum can participate in transport and the storage of oxygen.Ferrum can also promote to grow；Increase disease
Resistance；Regulation Tissue respiration, prevents fatigue；Constitute haemachrome, prevent and treat the anemia caused because of iron deficiency；Make animal
The red hair of skin is bright.
Trace element zinc is one of necessary trace element of animal, is likened to " biological element " of animal, since 1934 always
By rat test, year Todd et al. confirms that zinc is one of trace element necessary to Animal nutrition first since, people gradually send out
Existing, zinc is 200 various metals enzymes, hormone and the ingredient of insulin in animal body, can promote the growth promoter of body
And tissue regeneration, maintain the homergy of body, promote the normal of appetite, maintenance organ and sexual function, accelerate wound healing,
Protection skin health, also has great nutritive value strengthening the aspect such as immunologic mechanism, raising resistance.
The Major Nutrient physiological action of trace element manganese is as enzyme in carbohydrate, lipid, protein and cholesterol metabolism
Activation factor or ingredient.Manganese can participate in the transmission of nervus centralis media and the energy supply of axoneure, is to remain big
The requisite material of brain homergy function, if animal manganese deficiency may result in food ration decline, decreased growth, bone extremely, altogether
The phenomenons such as Ji imbalance, bradykinesia and breeding function are abnormal.Additionally, thyroid synthesis must have the enzyme catalysis ability activating manganese
Complete.Manganese ion also has much relations with chroma of hair, and chroma of hair light is then sufficient containing manganese, the intensely dark pool of hair then manganese deficiency.
Trace element chromium is one of required trace element of animal, plays special role in the carbohydrate metabolism and lipid metabolism of human body.Dynamic
Thing is extremely low to the absorption rate of inorganic chromium, less than 1%；And animal to the utilization rate of organic chromium up to 10%～25%.The life of chromium
Reason function is to coordinate to work together with other material controlling metabolism.Reactive compound chromium glycine can strengthen the biology of insulin
Effect, can be accelerated the utilization of glucose in animal body, and promote glucose to be converted into by activation phosphoglucomutase
Fat.Chromium can suppress the biosynthesis of cholesterol, reduces serum total cholesterol and triacylglycerol content and increasing high density fat egg
White cholesterol level, improves the lean meat percentage of letting animals feed.Chromium content in nucleoprotein is higher, and research finds that it can promote RNA's
Synthesis, chromium has an effect on aminoacid transhipment in vivo, promotes protein metabolism and growth promoter.Additionally, chromium can also antioxidation,
Improve immunologic function.
Trace element-selenium is some antioxidases (glutathion peroxidase) and the important composition portion of selenium-P albumen in animal body
Point, playing balance oxidation reduction reaction in vivo, promote that sugar metabolism etc. maintains physiological function to act on normally, research proves selenium
There is the effect improving animal immunizing power.Selenium is also the important element maintaining heart normal function, protected and repair to heart human body
Multiple effect.It is very capable that the heavy metals such as selenium and internal hydrargyrum, stannum, thallium, lead are combined, and forms composition metal selenium protein and solves
Poison, toxin expelling, thus resist the toxic heavy metal murder by poisoning to kidney, gonad and nervus centralis.Therefore, selenium can be as animal feed
Trace mineral supplement, improves agricultural byproducts selenium content and quality.
Trace element cobalt and vitamin B12After being combined into stomach, combine with " intrinsic factor " of parietal cell secretion, to prevent dimension raw
Element B12Destroyed by enteric microorganism, thus promote that it absorbs.Cobalt can also the hemopoietic system of bone marrow in stimulating animal body, help
Animal manufactures erythrocyte, distends the blood vessels and skin rubefaction, prevents anemia.Thyroxinic synthesis may be also required to cobalt, cobalt energy
The impact that antagonism iodine deficiency produces.
Microelement nickel is the biological element that animal is required.Nickel participates in serum calmness and enzyme and the activity of ribonucleic acid, can activating peptide
The activity of enzyme, all includes nickel in the structural stability of hormonal action and biomacromolecule and in general metabolic processes.
Nickel has the effect stimulating hemopoietic function, and erythrocyte, haemachrome and leukocyte can be stimulated to increase, and domestic animal lacks nickel and can cause deformity and take off
Color.
Trace element germanium has multiple biological activity, particularly synthesizes first from Japanese scholars shallow well one man of virtue and ability in 1967 and has extensive medicine
Since the organic germanium compounds Ge-132 of reason activity, the biological activity of germanium compound causes countries in the world and learns
The great interest of person.Research shows, germanium can strengthen by improving iodine and trilute, TA content
Organism metabolism function, and then promote the reproductive performance of animal；Meanwhile, on the one hand germanium make erythrocyte in blood (RBC) and blood
The quantity of Lactoferrin (HB) increases, the on the other hand formation of stimulating platelet cellulation (i.e. megalokaryocyte), thus stimulates
Hemopoietic function.Numerous studies show, organic germanium is to have promotion growth of animal, anticancer, antioxidation, blood fat reducing, removing freely
The biologic activity such as base, raising immunity.
Above-mentioned trace copper, ferrum, zinc, manganese, chromium, cobalt, selenium, nickel, germanium can not only maintain animal to give birth to normally by independent role
Reason activity, moreover it is possible to synergism promotes the absorption of other trace element and improves the physiologically active of animal.Manganese can affect and improve machine
The body utilization to copper.Scarce copper can increase the animal absorption to manganese, improves animal because lacking the anemia that copper causes.Zinc ion and manganese ion
Common participate in can defying age, maintain normal physiological function, improve the breeding age of kind of poultry.Selenium is micro-to other in body
Secondary element has regulating and controlling effect, can alleviate the toxicity of hydrargyrum, lead, arsenic.Zoopery is reported, selenium and zinc have synergism, can strengthen
Body's immunity.Copper mainly exists with cupric protease and plasma cell element (Ceruloplasmin) in animal body, affects hemopoietic
Process, promotes absorption and the utilization of ferrum, accelerates cell maturation.Copper can also with calcium synergism play strong skeleton, vessel softening,
Strengthen defensive enginery function.Ferrum, copper, zinc synergism can strengthen immunologic mechanism, strengthen anti-disease ability, and antibacterial infects in suppression,
Reduce the mortality rate of animal.
From the foregoing, it will be observed that trace copper, ferrum, zinc, manganese, chromium, cobalt, selenium, nickel, germanium can promote mutually the absorption in animal body
Utilization rate, maintains and improves some specific physiologically active in animal body, plays for safeguarding and improving the normal productive life of animal
Vital effect.They Deficiency of Intake, imbalance or shortage all can cause animal physiological abnormal to varying degrees or occur
Disease.But, as trace copper, ferrum, zinc, manganese and other trace element necessary to animal, the most employings are inorganic
Metallic salt form is as animal feed additive, and animal absorbs this inorganic salt must pass through various biological barrier, and it absorbs
Rate is low, and addition is big, and biological value is low, and major part also pollutes environment, to other nutritional labeling in feedstuff after feces is discharged
The activity of (such as vitamin etc.) has destruction.Additionally, copper, ferrum, zinc, manganese and other trace element are of a great variety, giving birth to
Produce in storage and transport process be easy to other composition each other and in feedstuff or with the oxygen generation Antagonistic reaction in air and oxidation
Reduction reaction, and then break in daily ration the balance between various trace element, cause between nutritional labeling unbalance, increase animal metabolism
Burden, affect the absorption in animal body of other nutrient substance and metabolism, and then have influence on health and the production performance of animal,
Severe patient even may result in animal and poisoning symptom occurs.
It addition, trace element basic salt has neutralization gastric acid, astringing to arrest diarrhea and antibacterial effect.Basic salt is the most water insoluble, with
In gastric acid and after, the metal ion that a discharges part is combined with hydrogen sulfide produced by enteral abnormal fermentation, adjustment gastrointestinal tract pH
Value, and form one layer of water-fast sulfide protecting film at intestinal mucosa wound surface, alleviate the food stimulation to gastrointestinal mucosa, one
Divide and be absorbed by organisms by free diffusing plasma channel.Additionally, the trace element ions such as copper ion are the most antibacterial, adjust intestinal
The function of interior colony balance.
Therefore, the advantage the most preferably combining above-mentioned nutritional labeling and trace element, make full use of the complementarity of each trace element,
Find a kind of reasonably combined, accurate proportioning, mix homogeneously, each other or and feedstuff in do not occur between other composition antagonism and
Redox reaction, the animal body feed additive to copper, ferrum, zinc, manganese and other trace elements absorption can be advantageously promoted,
The technical barrier that always this area faces for a long time.
Summary of the invention
The technical problem to be solved in the present invention is to overcome the deficiencies in the prior art, it is provided that a kind of technique simplifies, biological value is high,
Addition is low, growth promoting effect substantially, animal side reaction few, can life-time service and safety without drug-fast Animal nutrition additive
The compound bag of trace element, correspondingly provides this Animal nutrition additive trace element a kind of and is combined the preparation method and application of bag.
For solving above-mentioned technical problem, the technical scheme that the present invention proposes is the compound bag of a kind of Animal nutrition additive trace element,
The compound bag of described trace element is mainly by the many ore deposits of compound glycine, selenite (preferably sodium selenite or Calcium selenite .) and micro-
Secondary element basic salt form, the mass ratio of the described many ore deposits of compound glycine, selenite and trace element basic salt be (0.01～
100): (0.01～1): 1, the described many ore deposits of compound glycine comprise cupric glycinate, glycine ferrous, zinc glycinate and sweet ammonia
Acid manganese；Described trace element basic salt comprises trace copper, zinc, alkali formula chlorate, subcarbonate or alkali formula that manganese is corresponding
At least one in sulfate.
The trace element of the present invention is combined Bao Keyi difference customer requirement and is diluted to any concentration or granulation is ground into arbitrary size, should
Various trace elements synergism in the compound bag of trace element, each trace element each other or with other nutritional labeling in feedstuff it
Between Antagonistic reaction or redox reaction will not occur, the effect of its Synergistic is the most notable.
In the compound bag of above-mentioned Animal nutrition additive trace element, it is multiple that the compound bag of described trace element is preferably fowl trace element
Close bag, the compound bag of pig trace element, the compound bag of ruminant trace element, the compound bag of aquatic animal trace element, special
Kind of economic animal (special economic animal is wild domestication success, but the animal the most extensively used, as donkey,
Bears, masked civet etc.) it is combined bag with the compound bag of trace element or house pet trace element.
In technique scheme, described fowl with trace element be combined copper in bag, ferrum, zinc, manganese mass ratio be preferably (0.1～35):
(15～750): (5～150): (10～150)；
In technique scheme, described pig with trace element be combined copper in bag, ferrum, zinc, manganese mass ratio be preferably (1～200):
(15～750): (10～200): (8～150)；
In technique scheme, described ruminant with trace element be combined copper in bag, ferrum, zinc, manganese mass ratio be preferably (0.1～
35): (10～750): (3～150): (10～150)；
In technique scheme, described aquatic animal trace element be combined copper in bag, ferrum, zinc, manganese mass ratio be preferably (0.1～
25): (20～750): (15～200): (2～100)；
In technique scheme, described special economic animal trace element be combined copper in bag, ferrum, zinc, manganese mass ratio for (3～
200): (30～1250): (20～250): (10～150)；
In technique scheme, described house pet with trace element be combined copper in bag, ferrum, zinc, manganese mass ratio be preferably (3～200):
(30～1250): (20～250): (10～150).
The compound bag of above-mentioned Animal nutrition additive trace element is preferably granular preparation, also can wrap in the compound bag of described trace element
Containing carrier, described carrier preferably comprises the one in Maifanitum, zeolite powder, feldspar powder, Pulvis Talci, montmorillonite, white carbon
Or it is multiple.
In the compound bag of above-mentioned Animal nutrition additive trace element, the described many ore deposits of compound glycine further preferably comprise chromium glycine,
One or more in cobalt glycinate, nickel glycinate, glycine germanium.Described trace element basic salt further preferably comprises trace element
One or more in alkali formula chlorate, subcarbonate or subsulfate that cobalt, nickel, germanium are corresponding.
As total technology design, the present invention also provides for a kind of above-mentioned Animal nutrition additive trace element and is combined the system of bag
Preparation Method, comprises the following steps: raw material glycine and inorganic microelement compound is mixed by said ratio and is added to the water, adjusts
Joint pH value, to behind 3～10, is warming up to 30 DEG C～100 DEG C, and reaction pressure is 1～5 atmospheric pressure, be sufficiently stirred for reacting 0.5h～
3h, has reacted rear blowing, then add in product described selenite (preferably sodium selenite or Calcium selenite .) and
Trace element basic salt (also can mix a certain amount of chromium glycine), or add described selenite, trace element basic salt and
The mixture (also can mix a certain amount of chromium glycine) of carrier, makes homodisperse suspension, and last drying is pelletized and obtained
The compound bag of trace element；Wherein, the molal quantity of described glycine and always the rubbing of trace element in described inorganic microelement compound
Your ratio of number is (3.2～0.8): 1.
Multiple glycine chelate thing monomer reacts often by the processing method of conventional composite type feed additive respectively, after drying,
By proportioning, multiple glycine chelate thing monomer is dissolved, is dried, pelletizes, remixes again, compared with traditional method, the present invention
Above-mentioned preparation method is directly by multiple inorganic microelement compound and glycine hybrid reaction, without being dried and re-dissolved
Flow process, convection drying pelletizes, and this is not only greatly saved production stage and process costs, and makes the mixed of various compound
Close more uniform.
Above-mentioned Animal nutrition additive trace element is combined in the preparation method of bag, and described inorganic microelement compound preferably wraps
Containing Inorganic Copper, inorganic iron, inorganic zinc and inorganic manganese.Described Inorganic Copper preferably comprises copper chloride, copper sulfate, copper oxide, hydrogen-oxygen
Change at least one in copper, copper chloride hydroxide, basic copper sulfate, basic copper carbonate.Described inorganic iron preferably comprise ferrous chloride,
At least one in ferrous sulfate, ferrous carbonate.Described inorganic zinc preferably comprises zinc chloride, zinc sulfate, zinc hydroxide, oxidation
At least one in zinc, basic zinc sulfate, basic zinc carbonate, basic zinc chloride.Described inorganic manganese preferably comprise manganous chloride,
At least one (inorganic compound of trace element in the present invention in manganese sulfate, manganous hydroxide, manganous oxide, alkali formula manganese sulfate
All include that its hydrate forms, such as copper sulfate include that copper sulfate pentahydrate etc. includes a hydration containing water of crystallization form, ferrous sulfate
Ferrous sulfate etc. are containing water of crystallization form, lower same).
Above-mentioned Animal nutrition additive trace element is combined in the preparation method of bag, and described inorganic microelement compound is further preferably
Comprise at least one in inorganic cobalt, inorganic nickel, inorganic Ge；Described inorganic cobalt preferably comprises cobalt oxide, cobalt hydroxide, chlorination
At least one in cobalt, cobaltous sulfate, cobalt carbonate, basic cobaltous carbonate；Described inorganic nickel preferably comprise nickel oxide, nickel hydroxide,
At least one in Nickel dichloride., nickel sulfate, nickelous carbonate, basic nickel carbonate；Described inorganic Ge preferably comprises germanium oxide, dichloride
At least one in germanium, germanic acid calcium, copper germanate, sodium metagermanate, two sodium germanates, four sodium germanates.Chromium element can be directly with sweet ammonia
The form of acid chromium is added.
Above-mentioned preparation method can specifically use again any one in following three kinds of operation schemes.
Scheme 1: prepare a reactor, is dissolved in water by the described glycine prepared together with described inorganic microelement compound
In rear addition reactor, with alkaline solution regulation pH value to 3～10；Then open the air vent of reactor, close reactor
Charge door, the air inlet pipe toward reactor is filled with nitrogen until burning fire bavin extinguishes near described air vent, closes described air inlet pipe
And air vent；Starting to warm up to 30 DEG C～100 DEG C, be sufficiently stirred for reacting 0.5h～3h, reaction terminates rear blowing, then to reaction
Product adds described selenite and trace element basic salt (being now optionally added chromium glycine), or adds described
Selenite, trace element basic salt and the mixture of carrier (being now optionally added chromium glycine), make and uniformly divide
The suspension dissipated, in vacuum cooled spray dryer, drying and granulating obtains the compound bag of Animal nutrition additive trace element the most again
Finished product.
Method 2: prepare a reactor, adds after the described inorganic microelement compound prepared is dissolved in water in reactor,
Opening the air vent of reactor, close the charge door of reactor, the air inlet pipe toward reactor is filled with nitrogen until firing near air vent
The match burnt extinguishes, and closes described air inlet pipe and air vent；Start to warm up to 30 DEG C～100 DEG C, open described air vent, add
Material mouth and air inlet pipe, in the case of inflated with nitrogen, add the described glycine prepared in charge door, regulate pH with alkaline solution
Value, to 3～10, closes charge door, continues inflated with nitrogen until burning fire bavin extinguishes near air vent, closes air inlet pipe and aerofluxus
Mouthful；Being sufficiently stirred for reaction answers 0.5h～3h, reaction to terminate rear blowing, then add described selenite and trace in product
Element basic salt (is now optionally added chromium glycine), or adds described selenite, trace element basic salt and load
The mixture of body (being now optionally added chromium glycine), makes homodisperse suspension, the most again in vacuum cooled
In spray dryer, drying and granulating obtains that Animal nutrition additive trace element is compound is bundled into product.
Method 3: prepare a reactor, is dissolved in the described glycine prepared after water and adding in reactor, start to warm up to 30 DEG C～
100 DEG C, open the air vent of reactor, the charge door of reactor adds described inorganic microelement compound, molten by alkalescence
Liquid regulation pH value, to 3～10, closes charge door, and inflated with nitrogen in the air inlet pipe of reactor is until burning fire bavin near air vent
Extinguish, close air inlet pipe and air vent；Being sufficiently stirred for reacting 0.5h～3h, reaction terminates rear blowing, then adds in product
Enter described selenite and trace element basic salt (being now optionally added chromium glycine), or add described selenite,
Trace element basic salt and the mixture of carrier (being now optionally added chromium glycine), make homodisperse suspension,
Last the most again in vacuum cooled spray dryer drying and granulating obtain that Animal nutrition additive trace element is compound is bundled into product.
In above-mentioned each scheme, described inorganic microelement compound is selected raw material, and its proportioning raw materials meets above-mentioned technical side
In case, the quality of each element is than scope.Stirring reaction is carried out in sealed reactor, and its pressure-bearing scope is 1～5 atmospheric pressure,
During the compound many ore deposits of glycine of synthesis, be filled with the inert gas shieldings such as nitrogen, this avoid oxygen in air to ferrous iron,
Bivalent manganese, bivalence cobalt, germanous and the Oxidation of nickelous, animal has been reduced or avoided can not to other valence state trace element
The defect absorbed, even avoids harm that animal body may be caused by other valence state trace element (as animal can inhale
Receive ferrous iron, but ferric iron can not be absorbed).
In above-mentioned each scheme, the Drying Technology Parameter of the vacuum cooled spray dryer of the present invention is: in suspension, material fine powder is
2%～25% (W/V), quick pre-freeze material is to-5 DEG C～-40 DEG C, and dry vacuum is 0.01MPa～0.10MPa, heating plate temperature
Degree controls at 10 DEG C～50 DEG C, and condenser temperature is-10 DEG C～-50 DEG C, and flow-control is in 175ml/min～250ml/min, atomization
Device rotating speed is at 12000r/min～50000r/min.Spray with the vacuum cooled of existing high temperature drying granulation technique and pharmaceuticals industry
Dry technology is compared, and the vacuum cooled spray-drying process technology of the present invention, with water as solvent, utilizes carrier (as covered innovatively
De-stone) there is in animal the intestines and stomach the feature of adsorption and desorption, using carrier as slow releasing agent and adsorbent, it is different from medicine
The material of granulation to be dissolved in the organic solvent such as dehydrated alcohol, Eudragit E 100 by the vacuum cooled spray drying technology of industry
In, without using hydroxypropylcellulose, ethyl cellulose, polyacrylic resin class, poly-hydroxyalkyl vinyl class as slow releasing agent, with existing
High temperature drying granulation technique compare with the vacuum cooled spray drying technology of pharmaceuticals industry, the present invention not only raw material is more easy to get,
Cheaper, and safer environmental protection.
As the design of total technology, the present invention also provide for a kind of above-mentioned Animal nutrition additive trace element compound wrap in dynamic
Application in thing feed additive.In this application, described animal feed additive be particularly well-suited to pig animal feed additive,
Fowl animal feed additive, ruminant animal feed additive, aquatic animal animal feed additive, extraordinary economy
Animal animal feed additive or house pet animal feed additive.Compound the wrapping in of described trace element is added as animal feed
Addition during agent is preferably in animal feed per ton interpolation 0.5Kg～10Kg.More specifically, described trace element is compound wraps in
Meet in animal feed ration the content of trace element in the range of following as addition during animal feed additive: copper 0.1～
200ppm, ferrum 10～1250ppm, zinc 3～250ppm, manganese 2～150ppm, chromium 0～0.2ppm, cobalt 0～2ppm,
Nickel 0～10ppm, germanium 0～10ppm, selenium 0.01～0.5ppm.
Compared with prior art, it is an advantage of the current invention that: the compound product of contracting for fixed output quotas of the trace element of the present invention fully take into account different micro-
Different to its demand of secondary element and the complexity of glycine reactant and animal, by the further investigation theoretical to reaction principle,
Repeatedly summing up test experience, the most accurately having arranged in pairs or groups, it is new and effective to be suitable for many formula of variety classes and age level Animal needs
The compound bag of Animal nutrition additive trace element；The formula of the present invention and technique not only make glycine and copper, ferrum, zinc, manganese and
Its trace element reaction is more abundant, and owing to being added with the trace element basic salt with special physiological function, this makes respectively
Plant the collocation between trace element more reasonable, taken into account micro-element nutrition and be worth and antibacterial antidiarrheal convergence effect, the most dynamic
The absorption of thing and utilization so that it is quickly healthy growth breeding.Meanwhile, the trace element of the present invention is combined bag and can reduce feed storage
During trace element to vitamin and the oxidation of other nutrient substance and destruction, reduce trace element mutual antagonism in vivo and make
With, reduce in feedstuff other antinutritional factor (such as phytic acid) to its hurtful risk, it is ensured that feedstuff stable, high-quality,
Efficiently.
Trace element of the present invention is combined the preparation method of bag and not only simplify production technology, cost-effective, and decreases feedstuff and add
Add the dust in agent premix material production process, decrease product loss, optimize production environment, be conducive to safeguarding Manufacturing Worker's
Healthy；The preparation technology of the present invention also advantageously improves the mixing homogeneity in the animal feed course of processing, make copper, ferrum, zinc,
Manganese and other trace element mixture can prevent oxidized, mixing homogeneity is high, in the same size, not stratified, without moisture absorption caking,
No dust pollution.
Using compound for the Animal nutrition additive trace element of present invention bag as additive apply in animal feed time, not only
The generation of copper, ferrum, zinc, manganese and other trace element deficiency can be effectively prevented, and medicine can be slowly discharged in digestive tract
Effect and adsorb poisonous harmful microorganism, it is possible to significantly improve the utilization rate of trace element, be substantially reduced copper in animal excrements, ferrum,
Zinc, manganese and other trace element discharge capacity, effectively reduce the generation of the diseases such as the pollution to environment and diarrhoea；Also there is addition
Low, growth promoting effect is obvious, efficiency of feed utilization is high, animal side reaction is few, can add for a long time use and safety the most excellent without Drug resistance etc.
Point.Especially for different types of animal, according to its place of production, daily ration and the growth condition of production, proportioning reasonably combined, accurate
The compound bag of different types of trace element, meeting the various demands being frequently grown in productive life animal day.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described further, but does not limit the protection of the present invention because of specific examples below
Scope.
Embodiment 1: ruminant trace element is combined bag and preparation method thereof.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is multiple for beef cattle trace element
Closing bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, sodium selenite, trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.09: 36: 1 of trace element basic salt, the compound many ore deposits of glycine include sweet
Propylhomoserin copper, glycine ferrous, zinc glycinate, Mn-Gly, cobalt glycinate, chromium glycine, nickel glycinate and glycine germanium,
Trace element basic salt is copper chloride hydroxide and basic zinc chloride, and carrier is Pulvis Talci, montmorillonite and Maifanitum.This trace element
In compound bag, copper, ferrum, zinc, manganese, cobalt, selenium, chromium, nickel, the mass ratio of germanium are
2∶31∶18.5∶12.5∶0.25∶0.3∶0.2∶0.15∶0.24。
The trace element of the present embodiment is combined the preparation method of bag and comprises the following steps: prepare a reactor, and 61g five is hydrated sulfur
Acid copper, 960g Feromax, 408g Zinc sulfate monohydrate, 392g Manganous sulfate monohydrate, 11.4g six cobalt sulfate hydrate,
6.9g six hydration nickel sulfate, 4.8g germanous chloride are dissolved in 30Kg water together with 840g glycine, by the hydroxide of 0.1mol/L
Sodium solution regulation pH value is 6.8, opens the air vent of reactor, closes the charge door of reactor, and the air inlet pipe toward reactor is filled
Enter nitrogen until burning fire bavin extinguishes near air vent, close air inlet pipe and air vent；It is heated to 70 DEG C, is sufficiently stirred for
Reaction 1h.Reaction terminates rear blowing, adds 8.7g chromium glycine, 0.3Kg Pulvis Talci, 0.6Kg montmorillonite, 3.4g Monohydrated selenium dioxide
After sodium, 8.2g copper chloride hydroxide, 66g basic zinc chloride and 6.6Kg Maifanitum, make homodisperse suspension, by vacuum
In cooling spray drying machine, drying and granulating is crossed 80 mesh sieves and is the compound bag of the efficient trace element of beef cattle of the present embodiment.Trace element
In compound bag, the content (in terms of element) of each composition is: copper 0.20%, ferrum 3.10%, zinc 1.85%, manganese 1.25%, selenium 0.015%,
Chromium 0.01%, cobalt 0.025%, nickel 0.015%, germanium 0.024%, wherein aminoacid (with glycine) is 8.2%.This enforcement
The pressure-bearing scope of the sealed reactor of example stirring reaction is 1～5 atmospheric pressure.The drying process ginseng of vacuum cooled spray dryer
Number is: quickly pre-freeze material is to-12 DEG C, and dry vacuum is 0.04MPa, and temperature of heating plate controls at 35 DEG C, and condenser temperature is-20 DEG C,
Flow-control is at 220ml/min, and nebulizer rotating speed is 42000r/min.
Embodiment 2: fowl trace element is combined bag and preparation method thereof.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is multiple for laying hen trace element
Closing bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, sodium selenite, trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.02: 40: 1 of trace element basic salt, the compound many ore deposits of glycine include sweet
Propylhomoserin copper, glycine ferrous, zinc glycinate, Mn-Gly, cobalt glycinate, nickel glycinate and glycine germanium, trace element alkali
Formula salt is basic copper carbonate, basic zinc sulfate and basic nickel carbonate, and carrier is Pulvis Talci, montmorillonite and Maifanitum.This trace unit
In the compound bag of element, copper, ferrum, zinc, manganese, cobalt, selenium, chromium, nickel, the mass ratio of germanium are
3.9∶80∶54∶73∶0.25∶0.2∶0.2∶0.2∶0.25。
The trace element of the present embodiment is combined the preparation method of bag and comprises the following steps: prepare a reactor, is hydrated by 90.8g bis-
Dichloride copper, 2898g Iron dichloride tetrahydrate, 554g zinc oxide, 2681g tetra-are hydrated manganous chloride, 11.4g six hydrated sulfuric acid
After cobalt, 4.2g six hydration nickel sulfate and 5.0g germanous chloride are dissolved in 50Kg water, open the air vent of reactor, close reactor
Charge door, the air inlet pipe toward reactor is filled with nitrogen until burning fire bavin extinguishes near air vent, closes air inlet pipe and aerofluxus
Mouthful；Then heat to 80 DEG C, open the air vent of reactor, charge door and air inlet pipe, in the case of inflated with nitrogen, toward charging
Add 2885g glycine in Kou, after pH value is 5.8, close charge door with ammonia spirit regulation, continue inflated with nitrogen until aerofluxus
Near mouthful, burning fire bavin extinguishes, and closes air inlet pipe and air vent, is sufficiently stirred for reacting 1.2h.Reaction terminates rear blowing, adds
0.5Kg Pulvis Talci, 1.0Kg montmorillonite, 16.1g chromium glycine, 4.6g sodium selenite, 10.6g basic copper carbonate, 190g alkali
After formula zinc sulfate, 2.6g basic nickel carbonate and 1.5Kg Maifanitum, make homodisperse suspension, by vacuum cooled spray dried
In dry machine, drying and granulating crosses 60 mesh sieves, i.e. obtains the compound bag of fowl trace element of the present embodiment.The compound bag of trace element respectively becomes
The content (in terms of element) divided is: copper 0.39%, ferrum 8.0%, zinc 5.4%, manganese 7.3%, selenium 0.02%, chromium 0.02%, cobalt
0.025%, nickel 0.02%, germanium 0.025%, wherein aminoacid (with glycine) is 28.2%.The present embodiment stirring reaction is used
The pressure-bearing scope of sealed reactor be 1～5 atmospheric pressure.The Drying Technology Parameter of vacuum cooled spray dryer is: the most pre-
Freezing material extremely-10 DEG C, dry vacuum is 0.05MPa, and temperature of heating plate controls at 40 DEG C, and condenser temperature is-20 DEG C, flow control
System is at 200ml/min, and nebulizer rotating speed is at 45000r/min.
Embodiment 3: pig trace element is combined bag and preparation method thereof.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is fattening pig trace element
Compound bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, sodium selenite, trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.02: 20: 1 of trace element basic salt, the compound many ore deposits of glycine include sweet
Propylhomoserin copper, glycine ferrous, zinc glycinate, Mn-Gly, cobalt glycinate and nickel glycinate, trace element basic salt is alkali formula
Copper chloride, basic zinc sulfate and basic carbonate manganese, carrier is Pulvis Talci, montmorillonite and feldspar powder.In the compound bag of this trace element
Copper, ferrum, zinc, manganese, cobalt, selenium, the mass ratio of nickel are 5.4: 111.7: 60.4: 27: 0.2: 0.3: 0.25.
The trace element of the present embodiment is combined the preparation method of bag and comprises the following steps: prepare a reactor, by 2688g glycine
After being dissolved in 50Kg water, it is warming up to 98 DEG C, opens the air vent of reactor, the charge door of reactor adds 164g five and is hydrated
Copper sulfate, 3460g Feromax, 612g zinc oxide, 714g Manganous sulfate monohydrate, 6.8g sodium selenite, 11.5g
Six hydration nickel sulfate and 9.7g six cobalt sulfate hydrate, regulating pH value with the sodium hydroxide solution of 0.2mol/L is 6.5, and closedown adds
Material mouth, is filled with nitrogen in the air inlet pipe of reactor until burning fire bavin extinguishes near air vent, closes air inlet pipe and air vent；
It is sufficiently stirred for reacting 0.75h.Reaction terminates rear blowing, add 0.5Kg Pulvis Talci, 1.0Kg montmorillonite, 6.8g sodium selenite,
After 22.3g copper chloride hydroxide, 2211g basic zinc sulfate, 78.8g basic carbonate manganese and 1.1Kg feldspar powder, make dispersed
Suspension, drying and granulating in vacuum cooled spray dryer cross 40 mesh sieves, obtain the fattening pig of the present embodiment with new and effective
The compound bag of trace element.Trace element is combined the content (in terms of element) of each composition in bag: copper 0.54%, ferrum 11.17%,
Zinc 6.04%, manganese 2.70%, selenium 0.03%, cobalt 0.02%, nickel 0.025%, wherein aminoacid (with glycine) is 26.3%.
The pressure-bearing scope of the sealed reactor of the present embodiment stirring reaction is 1～5 atmospheric pressure.Being dried of vacuum cooled spray dryer
Technological parameter is: quickly pre-freeze material is to-18 DEG C, and dry vacuum is 0.05MPa, and temperature of heating plate controls at 35 DEG C, cold-trap temperature
Degree is for-20 DEG C, and flow-control is at 180ml/min, and nebulizer rotating speed is at 43000r/min.
Embodiment 4: fowl is combined the application wrapped in egg feedstuff as feed additive with trace element.
Trace element in embodiment 2 is combined bag and is used for the feeding experiment of laying hen.Select physically fit, body weight is close, egg productivity
Can be randomly divided into 3 groups by 28 similar week old commercial generation layer of green-shell egg, often organize 20 plumages, experimental period is 28d.Free choice feeding during test,
Drinking-water, observes chicken group's health status every day, records each group of egg number, egg size and feed consumption.Randomly draw often group the 14th day,
6 pieces of eggs of the 28th day, measure nutritional labeling.Loss on drying measures moisture；Copper sulfate-trace nitriding measures protein；
Soxhlet extraction methods measures fat.
During test, the control group fed place of production is the basal diet of the Northeast.Basal diet is by Semen Maydis, soybean cake, calcium carbonate, carbon
The compositions such as acid hydrogen calcium, conch meal, egg hydracid, multidimensional, sodium chloride, trace element.Containing crude protein (CP) 16.96% in basal diet,
ME 11.38kJ/kg, Ca 3.6%.P 0.65%, I 0.5mg/kg, Se 0.01mg/kg, Co 0.1mg/kg.Wherein, comparison
Group only feeds basal diet, tests and adds the trace element compound bag 0.5Kg of embodiment 2, test two in one group of basal diet per ton
Organize the trace element compound bag 1.0Kg adding embodiment 2 in basal diet per ton.Result of the test see table 1, shown in table 2.
Table 1: fowl trace element is combined the bag impact on performance in layers
As it can be seen from table 1 in the case of feed intake changes without significance, matched group and test group egg size are substantially without significance
Change, all has significant difference at laying rate and egg material than in index.This result of the test shows: add in laying hens essential ration
The trace element of the present invention can significantly improve laying rate and the egg material ratio of laying hen after being combined bag.
Table 2: fowl is combined the impact wrapping nutritional labeling main on egg with trace element
As can be seen from Table 2: compared with matched group, test group to the content of moisture, crude protein and crude fat in egg without significantly
Impact.The result explanation of table 2: the fowl of embodiment 2 is combined with trace element and wraps the main nutritional labeling on egg without impact.
Embodiment 5: pig is combined bag and as the application of feed additive in ablactational baby pig with trace element.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is multiple for piglet trace element
Closing bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, sodium selenite, trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.02: 25: 1 of trace element basic salt, the compound many ore deposits of glycine include sweet
Propylhomoserin copper, glycine ferrous, zinc glycinate, Mn-Gly, chromium glycine, cobalt glycinate, nickel glycinate and glycine germanium,
Trace element basic salt is basic zinc sulfate, basic zinc chloride and basic copper sulfate, and carrier is montmorillonite, feldspar powder and white carbon.
This trace element is combined copper in bag, ferrum, zinc, manganese, chromium, cobalt, selenium, nickel, the mass ratio of germanium are
7.4: 85: 70: 20: 0.15: 0.15: 0.2: 0.15: 0.18 (main nutrient composition and trace unit in the compound bag of this trace element
The mass fraction of element is: copper 0.74%, ferrum 8.50%, zinc 7.00%, manganese 2.00%, chromium 0.015%, selenium 0.02%, cobalt 0.015%,
Nickel 0.015%, germanium 0.018%, glycine 22.20%).The trace element of the present embodiment is combined the preparation technology of bag except raw material one-tenth
Divide and outside formula, remaining operating procedure and technological parameter are identical with the preparation technology in embodiment 3.
The trace element of the present embodiment is combined bag and is used for the feeding experiment of ablactational baby pig.Selection kind consistent (Du × long × big),
The anosis ablactational baby pig of health 108 that birth age in days is close, is randomly divided into matched group and two test group, often 6 repetitions of group,
6 pigs of each repetition, test group is using the compound bag of the trace element of the present embodiment as feed additive, and matched group is that pig is basic
Daily ration.Wherein, test the trace element compound bag 0.5Kg adding the present embodiment in one group of pig basal diet per ton, test two
Organizing and add trace element compound bag 1.0Kg in pig basal diet per ton, feeding time is 2 weeks, feeding effect such as table 3 below institute
Show.
Table 3: piglet trace element is combined the bag impact on Growth Performance of Weaning Piglets
Note: in upper table 3, same column shoulder marking-up parent phase is with representing that difference is not notable (p ＞ 0.05)；Same column shoulder marking-up mother differs table
Show significant difference (p ＜ 0.05), lower same.
The test data of upper table 3 shows: speed of growth significant difference (p ＜ 0.05) between test group and matched group；Although respectively testing
Group is not notable (p ＞ 0.05) with matched group difference in feed intake index, but significant difference (p in weightening finish and feedstuff-meat ratio index
＜ 0.05), along with the trace element of the present embodiment is combined the raising of bag addition, its weightening finish is improved trend, under feedstuff-meat ratio has
Fall trend, shows the trace element of the present invention and is combined bag and has good growth result to ablactational baby pig.
Embodiment 6: pig is combined bag and as the application of feed additive in grower pigs with trace element.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is grower pigs trace element
Compound bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, Calcium selenite., trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.9: 95: 1 of trace element basic salt, the compound many ore deposits of glycine include sweet
Propylhomoserin copper, glycine ferrous, zinc glycinate, Mn-Gly, chromium glycine and cobalt glycinate, trace element basic salt is alkali formula
Zinc chloride and copper chloride hydroxide, carrier is montmorillonite and feldspar powder.Copper in the compound bag of this trace element, ferrum, zinc, manganese, chromium,
Cobalt, the mass ratio of the selenium (main nutrient composition in this trace element compound bag A that is 3: 12: 10: 2: 0.03: 0.025: 0.02
And the mass fraction of trace element is: copper 3.00%, ferrum 12.00%, zinc 10.00%, manganese 2.00%, chromium 0.03%, selenium 0.02%,
Cobalt 0.025%, glycine 38.40%).The trace element of the present embodiment is combined the preparation technology of bag in addition to material composition and formula,
Remaining operating procedure and technological parameter are identical with the preparation technology in embodiment 3.
The trace element of the present embodiment is combined bag and is used for the feeding experiment of grower pigs.Select that 90 ages in days are close, weight differential not
Big grower pigs (three-way crossbred pigs) as test pig, according to body weight, principle that sex ratio is identical, is randomly divided into matched group
With test one, two groups, often 3 repetitions of group, each repetition 10 head growth pig, the nursing time is 28 days.Wherein matched group is
Basal diet, test one group of basal diet per ton adds the present embodiment trace element compound bag 0.5Kg, test two groups per ton
Basal diet adds the trace element compound bag 1.0Kg of the present embodiment.Result of the test is shown in Table 4.
Table 4: pig trace element is combined the bag impact on grower pigs growth performance
| Group | Original body mass/kg | Average daily gain/kg | Average every feed consumption/kg | Feedstuff-meat ratio |
| Matched group | 45.31±0.98a | 0.67±0.12a | 40.97±1.59a | 2.17±0.15a |
| Test one group | 45.27±0.67a | 0.75±0.08b | 42.14±1.28b | 2.01±0.11b |
| Test two groups | 45.15±0.48a | 0.77±0.04c | 42.58±1.27c | 1.97±0.16c |
By upper table 4 it can be seen that during testing test group reach notable in the average daily gain of matched group, feedstuff-meat ratio index
Property poor (p ＜ 0.05), test group difference is the most notable (p ＞ 0.05).The result of above-mentioned table 4 shows: test group with compare
The speed of growth significant difference (p ＜ 0.05) of grower pigs between group；Significant difference (p ＜ in feed intake, weightening finish and feedstuff-meat ratio index
0.05), along with the present embodiment trace element is combined the raising of bag addition, its weightening finish is improved trend, and feedstuff-meat ratio has decline to become
Gesture, shows the trace element of the present invention and is combined bag and has good growth result to grower pigs.
Embodiment 7: pig is combined the application wrapped in fattening pig feedstuff as additive with trace element.
Trace element in embodiment 3 is combined bag and is used for the feeding experiment of fattening pig.Select that 90 ages in days are close, weight differential
Little fattening pig (three-way crossbred pigs) as test pig, according to body weight, principle that sex ratio is identical, is randomly divided into comparison
Group and test one, two groups, often 3 repetitions of group, 10 fattening pigs of each repetition, the nursing time is 35 days.Wherein, comparison
Daily ration based on group, tests efficient trace element compound bag 0.5Kg, the test adding embodiment 3 in one group of basal diet per ton
Two groups of basal diets per ton add the trace element compound bag 1.0Kg of embodiment 3.Result of the test is as shown in table 5 below.
Table 5: pig trace element is combined the bag impact on Growth of Pigs performance
| Group | Original body mass kg | Average daily gain kg | Average every feed consumption kg | Feedstuff-meat ratio |
| Matched group | 79.31±1.24a | 0.75±0.15a | 70.52±2.49a | 2.68±0.23a |
| Test one group | 79.28±0.89a | 0.82±0.09b | 72.97±2.27b | 2.55±0.17b |
| Test two groups | 79.14±0.78a | 0.86±0.07c | 75.08±2.21c | 2.49±0.15c |
As can be seen from Table 5, during testing, test group reaches notable in the average daily gain of matched group, feedstuff-meat ratio index
Sex differernce (p ＜ 0.05), significant difference (p ＜ 0.05) between test group.The result of upper table 5 shows: fertile between test group and matched group
Educate the speed of growth significant difference (p ＜ 0.05) of pig；Significant difference (p ＜ 0.05) in feed intake, weightening finish and feedstuff-meat ratio index, with
Trace element and be combined the raising of bag addition, weightening finish is improved trend, feedstuff-meat ratio has downward trend for it, and this shows the present invention
Efficient trace element be combined bag fattening pig had good fattening effect.
Embodiment 8: pig is combined bag and as the application of feed additive in sow feed with trace element.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is grower pigs trace element
Compound bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, sodium selenite, trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.02: 3.5: 1 of trace element basic salt, the compound many ore deposits of glycine include
Cupric glycinate, glycine ferrous, zinc glycinate, Mn-Gly, chromium glycine, cobalt glycinate, trace element basic salt is alkali
Formula cobalt carbonate and basic zinc carbonate, carrier is Pulvis Talci and montmorillonite.Copper in the compound bag of this trace element, ferrum, zinc, manganese, chromium,
Cobalt, the mass ratio of selenium are 1.8: 12.4: 10.7: 8: 0.01: 0.05: 0.01, and (in the compound bag of this trace element, Major Nutrient becomes
Divide and the mass fraction of trace element is: copper 1.80%, ferrum 12.40%, zinc 10.70%, manganese 8.0%, chromium 0.01%, selenium 0.01%,
Cobalt 0.05%, glycine 25.2%).The trace element of the present embodiment is combined the preparation technology of bag in addition to material composition and formula,
Remaining operating procedure and technological parameter are identical with the preparation technology in embodiment 3.
The trace element of the present embodiment is combined bag and is used for the feeding experiment of brood sow.Select the Duluke's sow of same parity,
Being divided into three groups (matched group and tests one, two groups), often group 20, often group is bred with 2～3 Duroc boars, it is desirable to
Within an oestrus, complete breeding, wherein daily ration based on matched group, test interpolation the present embodiment in one group of basal diet per ton
Trace element compound bag 0.5Kg, test the trace element compound bag 1.0Kg adding the present embodiment in two groups of basal diets per ton.
Result of the test is as shown in table 6.
Table 6: pig trace element is combined the bag impact on brood sow production performance
As can be seen from Table 6, for nascent young number of living, matched group and test group reach significant difference (p ＜ 0.05), but
Weigth at birth is not affected；Along with the change of feeding time, the young number of living of its 21 age in days changes the most therewith, and litter weight starts performance
Go out larger difference, and survival rate has the difference (p ＜ 0.05) of significance；During 42 age in days, the live performance of young number and the phase of 21 ages in days
Seemingly, incubation rate also reaches significant difference (p ＜ 0.05).Use above result shows: add the general trace of boar of the present embodiment
The test group of elements compounding bag, the young number of living of brood sow, the survival rate in later stage, incubation rate all have carrying of significance compared with matched group
Height, and litter weight relatively matched group is also greatly improved, this trace element showing the present invention is combined the bag breeding to brood sow
Performance improves a lot.
Embodiment 9: cattle is combined the application wrapped in calf forage as feed additive with trace element.
Trace element in above-described embodiment 1 is combined bag and is used for the feeding experiment of calf.Select same head black-and-white flower breeding oxen with
21 calves (80～90 age in days) that the cow hybridization of primiparity Qin Chuan is given birth to are test cattle, are randomly divided into 3 groups, often group 7.
Wherein daily ration based on matched group, test one group of basal diet per ton adds embodiment 1 trace element compound bag 1.0Kg,
Test the trace element compound bag 2.0Kg adding embodiment 1 in two groups of basal diets per ton.Experimental period 37d, wherein preliminary trial period altogether
7d, is just trying phase 30d.Result of the test see table 7.
Table 7: cattle trace element is combined the bag impact on calf growth performance
| Group | Original body mass/kg | End weight/kg | Average daily gain/kg |
| Matched group | 58.4±1.48a | 76.3±1.61a | 0.60±0.08a |
| Test one group | 57.6±1.36a | 79.9±1.84b | 0.74±0.09b |
| Test two groups | 58.0±1.16a | 84.8±0.84c | 0.89±0.07c |
As can be seen from Table 7, under conditions of original body mass is more or less the same, test group and the average daily gain of matched group have
Significant difference (p ＜ 0.05), and significant difference (p ＜ 0.05) between test group.The result of upper table 7 shows: test group with compare
The speed of growth significant difference (p ＜ 0.05) of calf between group；And along with the trace element of the present invention is combined the raising of bag addition,
Its daily gain is improved trend, and this trace element showing the present invention is combined bag good growth-promoting effect to calf.
Embodiment 10: fresh-water fishes are combined bag and as the application of feed additive in Russia's carp feed with trace element.
The compound bag of the Animal nutrition additive trace element of a kind of present invention, the compound bag of this trace element is fresh-water fishes trace element
Compound bag, the compound bag of this trace element is mainly made up of the many ore deposits of compound glycine, sodium selenite, trace element basic salt and carrier,
Sodium selenite, the compound many ore deposits of glycine and the mass ratio 0.08: 7.5: 1 of trace element basic salt, the compound many ore deposits of glycine include
Cupric glycinate, glycine ferrous, zinc glycinate, Mn-Gly, chromium glycine, cobalt glycinate, trace element basic salt is alkali
Formula zinc sulfate, copper chloride hydroxide and basic cobaltous carbonate, carrier is zeolite powder.Copper in the compound bag of this trace element, ferrum, zinc, manganese,
Chromium, cobalt, the mass ratio of the selenium (main nutrient composition in the compound bag of this trace element that is 8: 100: 80: 40: 0.2: 0.4: 0.5
And the mass fraction of trace element is: copper 0.80%, ferrum 10.00%, zinc 8.00%, manganese 4.00%, chromium 0.02%, selenium 0.05%,
Cobalt 0.04%, glycine 29.57%).The trace element of the present embodiment is combined the preparation technology of bag in addition to material composition and formula,
Remaining operating procedure and technological parameter are identical with the preparation technology in embodiment 3.
The trace element of the present embodiment is combined bag and is used for the feeding experiment of Russia Cyprinus carpio.Select healthy, uniform, original body mass
For Russian Cyprinus carpio 1500 tail of (104.4 ± 2.1) g, it is equally divided into 5 process, each process 3 repetition, each repetition
100 tails, each pond is 1 and repeats cement pit specification 6m × 9m.Fingerling is bought back and was grouped immediately the same day, uses bacterium after packet
Only splash sterilization；In 1st week, dead fish selects the standby fish substitute that specification is close, is gradually completing testing material and raises former after packet in 3d
The replacement of material；Throw something and feed every day under normal circumstances 4 times during test, start aerator according to weather condition in good time；During test often
Two weeks chlorinated product is sterilized 1 time, changes weekly water 1/3, and dissolved oxygen keeps more than 6mg/L, experimental period 70d.Wherein, comparison
Daily ration based on group, tests the fresh-water fishes trace element compound bag 0.5Kg adding the present embodiment in one group of basal diet per ton,
Test the fresh-water fishes trace element compound bag 1.0Kg adding the present embodiment in two groups of basal diets per ton.Wherein, basal diet
Middle crude protein 35.00%, crude fat 5.40%, available phosphorus 0.60%.Result of the test is shown in Table 8.
Table 8: fresh-water fishes are combined the impact wrapped Russia's carp growth performance with trace element
| Project | Matched group | Test one group | Test two groups |
| Initial weight/g | 102.9±2.2a | 105.4±1.0a | 104.4±2.9a |
| End weight/g | 506.0±4.5a | 518.3±9.1ab | 518.0±14.3ab |
| Weightening finish/g | 403.1±3.1a | 412.9±9.1ab | 413.6±11.4ab |
| Body weight increase rate/% | 263.6±3.8a | 265.7±6.1sb | 267.8±2.6b |
| Take the photograph bait amount/g | 520.0±12.4a | 520.2±9.9a | 517.0±16.8a |
| Feed coefficient | 1.29±0.02ab | 1.26±0.02b | 1.25±0.05b |
| Mortality rate/% | 2.3a | 1.9b | 1.5b |
As can be seen from Table 8: test group and matched group do not have significant change taking the photograph in bait amount, but at weightening finish, body weight increase rate, bait
Significant difference (p ＜ 0.05), and significant difference (p ＜ 0.05) between test group is all had on material coefficient and mortality rate.The knot of upper table 8
Fruit shows: the growth of Cyprinus carpio and survival benefit significant difference (p ＜ 0.05) between test group and matched group；And micro-along with the present invention
Secondary element is combined the raising of bag addition, and body weight increase rate is improved trend, mortality rate and feed coefficient and all has a declining tendency,
This trace element showing the present invention is combined bag has good growth result to Russia Cyprinus carpio.
Claims (5)
1. an Animal nutrition additive trace element is combined the preparation method of bag, the compound bag of described trace element is made up of the many ore deposits of compound glycine, selenite and trace element basic salt, the mass ratio of the described many ore deposits of compound glycine, selenite and trace element basic salt is (0.01～100): (0.01～1): 1, and the described many ore deposits of compound glycine are made up of cupric glycinate, glycine ferrous, zinc glycinate and Mn-Gly；Described trace element basic salt comprises at least one in alkali formula chlorate, subcarbonate or the subsulfate that trace copper, zinc, manganese are corresponding；
The compound bag of described trace element is the compound bag of fowl trace element, the compound bag of ruminant trace element, the compound bag of aquatic animal trace element, the compound bag of special economic animal trace element or the compound bag of house pet trace element；
Described fowl trace element be combined copper in bag, ferrum, zinc, manganese mass ratio for (0.1～35): (15～750): (5～150): (10～150)；
Described ruminant trace element be combined copper in bag, ferrum, zinc, manganese mass ratio for (0.1～35): (10～750): (3～150): (10～150)；
Described aquatic animal trace element be combined copper in bag, ferrum, zinc, manganese mass ratio for (0.1～25): (20～750): (15～200): (2～100)；
Described special economic animal trace element be combined copper in bag, ferrum, zinc, manganese mass ratio for (3～200): (30～1250): (20～250): (10～150)；
Described house pet trace element be combined copper in bag, ferrum, zinc, manganese mass ratio for (3～200): (30～1250): (20～250): (10～150)；
The described many ore deposits of compound glycine also comprise one or more in chromium glycine, cobalt glycinate, nickel glycinate, glycine germanium；Described trace element basic salt also comprises one or more in alkali formula chlorate, subcarbonate or the subsulfate that trace element cobalt, nickel, germanium are corresponding；
The compound bag of described trace element is granular preparation, also includes carrier in the compound bag of described trace element, and described carrier comprises one or more in Maifanitum, zeolite powder, feldspar powder, Pulvis Talci, montmorillonite, white carbon；
Described preparation method comprises the following steps: raw material glycine and inorganic microelement compound is mixed by said ratio and is added to the water, regulation pH value is to behind 3～10, it is warming up to 30 DEG C～100 DEG C, reaction pressure is 1～5 atmospheric pressure, it is sufficiently stirred for reacting 0.5h～3h, react rear blowing, described selenite and trace element basic salt is added again in product, or add described selenite, trace element basic salt and the mixture of carrier, making homodisperse suspension, last drying is pelletized and is obtained the compound bag of trace element；Wherein, the molal quantity of described glycine is (3.2～0.8) with the ratio of the total mole number of trace element in described inorganic microelement compound: 1；
Above-mentioned preparation method specifically uses any one in following three kinds of operating procedures:
1) prepare a reactor, add after the described glycine prepared is dissolved in together with described inorganic microelement compound water in reactor, with alkaline solution regulation pH value to 3～10；Then opening the air vent of reactor, close the charge door of reactor, the air inlet pipe toward reactor is filled with nitrogen until burning fire bavin extinguishes near described air vent, closes described air inlet pipe and air vent；Start to warm up to 30 DEG C～100 DEG C, it is sufficiently stirred for reacting 0.5h～3h, reaction terminates rear blowing, described selenite and trace element basic salt is added again in product, or add described selenite, trace element basic salt and the mixture of carrier, now being optionally added chromium glycine, make homodisperse suspension, in vacuum cooled spray dryer, drying and granulating obtains that Animal nutrition additive trace element is compound is bundled into product the most again；
2) reactor is prepared, add after the described inorganic microelement compound prepared is dissolved in water in reactor, open the air vent of reactor, close the charge door of reactor, air inlet pipe toward reactor is filled with nitrogen until burning fire bavin extinguishes near air vent, closes described air inlet pipe and air vent；Start to warm up to 30 DEG C～100 DEG C, open described air vent, charge door and air inlet pipe, in the case of inflated with nitrogen, the described glycine prepared is added in charge door, with alkaline solution regulation pH value to 3～10, close charge door, continue inflated with nitrogen until burning fire bavin extinguishes near air vent, close air inlet pipe and air vent；It is sufficiently stirred for reacting 0.5h～3h, reaction terminates rear blowing, described selenite and trace element basic salt is added again in product, or add described selenite, trace element basic salt and the mixture of carrier, now it is optionally added chromium glycine, making homodisperse suspension, in vacuum cooled spray dryer, drying and granulating obtains that Animal nutrition additive trace element is compound is bundled into product the most again；
3) reactor is prepared, add after the described glycine prepared is dissolved in water in reactor, start to warm up to 30 DEG C～100 DEG C, open the air vent of reactor, in the charge door of reactor, add described inorganic microelement compound, with alkaline solution regulation pH value to 3～10, close charge door, inflated with nitrogen in the air inlet pipe of reactor, until burning fire bavin extinguishing near air vent, closes air inlet pipe and air vent；It is sufficiently stirred for reacting 0.5h～3h, reaction terminates rear blowing, described selenite and trace element basic salt is added again in product, or add described selenite, trace element basic salt and the mixture of carrier, now it is optionally added chromium glycine, making homodisperse suspension, in vacuum cooled spray dryer, drying and granulating obtains that Animal nutrition additive trace element is compound is bundled into product the most again.
Preparation method the most according to claim 1, it is characterised in that: described inorganic microelement compound comprises Inorganic Copper, inorganic iron, inorganic zinc and inorganic manganese；Described Inorganic Copper comprises at least one in copper chloride, copper sulfate, copper oxide, Copper hydrate, copper chloride hydroxide, basic copper sulfate, basic copper carbonate；Described inorganic iron comprises at least one in ferrous chloride, ferrous sulfate, ferrous carbonate；Described inorganic zinc comprises at least one in zinc chloride, zinc sulfate, zinc hydroxide, zinc oxide, basic zinc sulfate, basic zinc carbonate, basic zinc chloride；Described inorganic manganese comprises at least one in manganous chloride, manganese sulfate, manganous hydroxide, manganous oxide, alkali formula manganese sulfate.
Preparation method the most according to claim 1 and 2, it is characterised in that: described inorganic microelement compound also comprises at least one in inorganic cobalt, inorganic nickel, inorganic Ge；Described inorganic cobalt comprises at least one in cobalt oxide, cobalt hydroxide, cobaltous chloride, cobaltous sulfate, cobalt carbonate, basic cobaltous carbonate；Described inorganic nickel comprises at least one in nickel oxide, nickel hydroxide, Nickel dichloride., nickel sulfate, nickelous carbonate, basic nickel carbonate；Described inorganic Ge comprises at least one in germanium oxide, germanous chloride, germanic acid calcium, copper germanate, sodium metagermanate, two sodium germanates, four sodium germanates.
4. the Animal nutrition additive trace element that a preparation method as any one of claims 1 to 3 obtains is combined the application wrapping in animal feed additive；
Described animal feed additive comprises fowl animal feed additive, ruminant animal feed additive, aquatic animal animal feed additive, special economic animal animal feed additive or house pet animal feed additive；Described trace element is combined and wraps in as addition during animal feed additive is interpolation 0.5kg～10kg in animal feed per ton.
Application the most according to claim 4, it is characterized in that, described trace element is combined to wrap in and meets in animal feed ration the content of trace element in the range of following as addition during animal feed additive: copper 0.1～200ppm, ferrum 10～1250ppm, zinc 3～250ppm, manganese 2～150ppm, chromium 0～0.2ppm, cobalt 0～2ppm, nickel 0～10ppm, germanium 0～10ppm, selenium 0.01～0.5ppm.
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| CN103005187B (en) * | 2012-12-07 | 2014-03-05 | 浙江群大饲料有限公司 | Composite trace element additive for three-yellow broiler |
| CN104905035A (en) * | 2015-05-25 | 2015-09-16 | 广东温氏食品集团股份有限公司 | A feed for reducing the morbidity of ascites syndromes in broiler chickens |
| CN105236469B (en) * | 2015-09-17 | 2017-05-31 | 长沙兴嘉生物工程股份有限公司 | The preparation method and applications of selenous acid cu zn |
| CN106359899B (en) * | 2016-08-31 | 2019-12-20 | 长沙兴嘉生物工程股份有限公司 | Composite fat powder, preparation method thereof and application thereof in ruminant feeding |
| CA3064854A1 (en) * | 2017-05-26 | 2018-11-29 | Nutreco Ip Assets B.V. | Pet food product |
| CN107751613B (en) * | 2017-11-30 | 2021-06-11 | 福建九为生物技术有限公司 | Glycine type additive premixed feed for lactating sows |
| CN111978189B (en) * | 2020-08-25 | 2023-06-06 | 重庆森乐美生物科技有限公司 | Preparation method and production system of glycine complex manganese salt premix |
| CN112062686A (en) * | 2020-08-26 | 2020-12-11 | 重庆森乐美生物科技有限公司 | Preparation method and production system of glycine complexed ferrous salt premix |
| CN113080319A (en) * | 2021-04-27 | 2021-07-09 | 云南农业大学 | Organic trace element premix feed formula for beef cattle |
| CN114162871A (en) * | 2021-11-23 | 2022-03-11 | 广西锰华新能源科技发展有限公司 | Preparation method of basic manganese sulfate |
| CN114304441A (en) * | 2022-01-10 | 2022-04-12 | 长沙兴嘉生物工程股份有限公司 | Organic trace element compound bag for fish and preparation method and application thereof |
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