CN102533524B - 生物芯片 - Google Patents

生物芯片 Download PDF

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Publication number
CN102533524B
CN102533524B CN201110412960.5A CN201110412960A CN102533524B CN 102533524 B CN102533524 B CN 102533524B CN 201110412960 A CN201110412960 A CN 201110412960A CN 102533524 B CN102533524 B CN 102533524B
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CN
China
Prior art keywords
liquid
biochip
container
reaction
reaction solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201110412960.5A
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English (en)
Chinese (zh)
Other versions
CN102533524A (zh
Inventor
小枝周史
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seiko Epson Corp
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Seiko Epson Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN102533524A publication Critical patent/CN102533524A/zh
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Publication of CN102533524B publication Critical patent/CN102533524B/zh
Expired - Fee Related legal-status Critical Current
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0469—Buoyancy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7069—With lock or seal
    • Y10T137/71—With seal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201110412960.5A 2010-12-14 2011-12-12 生物芯片 Expired - Fee Related CN102533524B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010-277759 2010-12-14
JP2010277759A JP5773119B2 (ja) 2010-12-14 2010-12-14 バイオチップ

Publications (2)

Publication Number Publication Date
CN102533524A CN102533524A (zh) 2012-07-04
CN102533524B true CN102533524B (zh) 2016-03-16

Family

ID=45491244

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201110412960.5A Expired - Fee Related CN102533524B (zh) 2010-12-14 2011-12-12 生物芯片

Country Status (4)

Country Link
US (3) US8679424B2 (enExample)
EP (1) EP2465608A3 (enExample)
JP (1) JP5773119B2 (enExample)
CN (1) CN102533524B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5867668B2 (ja) 2010-12-01 2016-02-24 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル方法
JP5896100B2 (ja) 2011-03-01 2016-03-30 セイコーエプソン株式会社 熱サイクル装置
JP2013208066A (ja) 2012-03-30 2013-10-10 Seiko Epson Corp 熱サイクル装置及び熱サイクル装置の制御方法
JP5971463B2 (ja) * 2012-03-30 2016-08-17 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル装置の制御方法
JP5967361B2 (ja) 2012-06-06 2016-08-10 セイコーエプソン株式会社 熱サイクル装置
JP6298048B2 (ja) 2012-06-28 2018-03-20 フルオレセントリック，インコーポレイテッド 化学的インジケータデバイス
JP2015073513A (ja) * 2013-10-11 2015-04-20 セイコーエプソン株式会社 核酸抽出用デバイス、核酸抽出用キット、及び核酸抽出用装置
JP2015154722A (ja) 2014-02-20 2015-08-27 セイコーエプソン株式会社 核酸増幅反応容器及び核酸増幅反応装置
JP2015159791A (ja) * 2014-02-28 2015-09-07 セイコーエプソン株式会社 核酸増幅方法
JP2015188343A (ja) * 2014-03-27 2015-11-02 セイコーエプソン株式会社 バイオチップ
JP2015188377A (ja) * 2014-03-28 2015-11-02 セイコーエプソン株式会社 核酸増幅反応用カートリッジ及び核酸増幅装置
GB2526520B (en) 2014-04-04 2021-08-18 It Is Int Ltd Biochemical reaction system
JP2015223083A (ja) * 2014-05-26 2015-12-14 セイコーエプソン株式会社 核酸増幅反応装置の制御方法
JP2015223112A (ja) * 2014-05-28 2015-12-14 セイコーエプソン株式会社 核酸増幅反応装置
JP2016096762A (ja) * 2014-11-20 2016-05-30 セイコーエプソン株式会社 核酸増幅反応装置及び核酸増幅方法
EP3752479A1 (en) * 2018-02-15 2020-12-23 Evonik Operations GmbH Extraction of alkanoic acids
CN111909841B (zh) * 2019-05-08 2024-08-27 世纪一束(杭州)医学诊断科技有限公司 一种变温离心装置
CN111879057B (zh) * 2020-07-23 2021-10-22 潍坊医学院 一种基于液氮的转运样本的杯子

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252250A (en) * 1990-02-21 1993-10-12 Bridgestone Corporation Electrorheological fluids comprising dielectric particulates dispersed in a highly electrically insulating oily medium
CN1924576A (zh) * 2005-08-30 2007-03-07 精工爱普生株式会社 生物芯片制造方法以及生物芯片制造装置
JP2009136250A (ja) * 2007-12-10 2009-06-25 Seiko Epson Corp 生体試料反応用チップ、生体試料反応装置、および生体試料反応方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3012699B2 (ja) * 1990-02-21 2000-02-28 株式会社ブリヂストン 電気粘性流体
JP3120453B2 (ja) * 1997-06-19 2000-12-25 トヨタ自動車株式会社 微小液滴の保持方法、反応方法
JP2004033146A (ja) * 2002-07-05 2004-02-05 Terametsukusu Kk 遺伝子増幅反応モニター
JP3699721B1 (ja) * 2004-10-28 2005-09-28 株式会社石川製作所 検体試料の遠心分注方法及び遠心分注装置
JP4792278B2 (ja) * 2005-11-24 2011-10-12 株式会社島津製作所 反応容器及び反応容器処理装置
JP4626891B2 (ja) * 2007-01-29 2011-02-09 ヤマハ株式会社 温度制御装置
JP2009116191A (ja) * 2007-11-08 2009-05-28 Fuji Xerox Co Ltd 表示媒体、及び表示装置
JP5867668B2 (ja) * 2010-12-01 2016-02-24 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252250A (en) * 1990-02-21 1993-10-12 Bridgestone Corporation Electrorheological fluids comprising dielectric particulates dispersed in a highly electrically insulating oily medium
CN1924576A (zh) * 2005-08-30 2007-03-07 精工爱普生株式会社 生物芯片制造方法以及生物芯片制造装置
JP2009136250A (ja) * 2007-12-10 2009-06-25 Seiko Epson Corp 生体試料反応用チップ、生体試料反応装置、および生体試料反応方法

Also Published As

Publication number Publication date
CN102533524A (zh) 2012-07-04
EP2465608A3 (en) 2014-02-26
JP5773119B2 (ja) 2015-09-02
EP2465608A2 (en) 2012-06-20
JP2012125169A (ja) 2012-07-05
US8679424B2 (en) 2014-03-25
US20160089674A1 (en) 2016-03-31
US20140147914A1 (en) 2014-05-29
US20120145260A1 (en) 2012-06-14

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Granted publication date: 20160316

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