CN102526412A - Chinese medicine composition for treating myocardial infarction - Google Patents
Chinese medicine composition for treating myocardial infarction Download PDFInfo
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- CN102526412A CN102526412A CN2010106215070A CN201010621507A CN102526412A CN 102526412 A CN102526412 A CN 102526412A CN 2010106215070 A CN2010106215070 A CN 2010106215070A CN 201010621507 A CN201010621507 A CN 201010621507A CN 102526412 A CN102526412 A CN 102526412A
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Abstract
The invention relates to a Chinese medicine composition for treating myocardial infarction. The Chinese medicine composition is characterized by being prepared from the following traditional Chinese medicine raw medicines in parts by weight: 13-50 parts of gecko, 50-100 parts of medical stone, 30-50 parts of the root of red-rooted salvia, 50-100 parts of Astragalus mongholicus, 15-50 parts of Chinese rhubarb, 15-30 parts of Ligusticum wallichii, 15-30 parts of the bidentate achyranthes root, 15-50 parts of red peony root, 10-30 parts of Chinese angelica, 18-50 parts of rehmannia root, 18-50 parts of notopterygium root, 15-30 parts of divaricate saposhnikovia root, 1-10 parts of musk, 10-30 parts of nutgrass galingale rhizome, 10-30 parts of purple perilla, 10-30 parts of dried tangerine or orange peel, and 10-20 parts of rhizoma corydalis. The Chinese medicine composition is capable of relieving symptoms caused by the myocardial infarction in a short time after patients take the Chinese medicine composition, so that the function of delaying symptom occurrence is achieved; and furthermore, the Chinese medicine composition has an obvious treatment effect after the patients suffering from the myocardial infarction are treated.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly a kind of Chinese medicine composition of treating sequela such as myocardial infarction, angina pectoris, coronary heart disease.
Background technology
Cardiovascular and cerebrovascular disease serious harm human healths such as myocardial infarction, angina pectoris, coronary heart disease are regarded as harm humans healthy " No.1 killer " by World Health Organization (WHO).The whole world has 1,500 ten thousand people to die from cardiovascular and cerebrovascular disease every year approximately, and China has 4,000,000 people to die from this disease every year approximately, accounts for more than 3/5 of death toll.Cardiovascular and cerebrovascular disease high incidence the highest country in the whole world is in China.The treatment cardiovascular and cerebrovascular disease becomes the important public health problem of common concern.Symptoms such as the cerebral palsy that takes place to cause after myocardial infarction, angina pectoris, the coronary heart disease the patient, unconsciousness, hemiplegia; To the patient and at one's side the misery brought of relatives not second to ill itself, and make patient and family members can't bear the heavy load because of the required high cost of the treatment of its sequela.Up to now, people also do not have better medicine to the fatal disease and the sequela thereof of such puzzlement human life safety, though there is the Western medicine pills for curing heart disease class medicine can the respite symptom, its side effect meeting produces certain influence to the patient.And to the ailing patient of having taken place and the sequela that causes still lacks therapy measure and effective medicine at present.Therefore, people expect effective in cure better treatment myocardial infarction, angina pectoris, coronary heart disease and alleviate the medicine of the sequela that causes because of such disease.
Summary of the invention
The objective of the invention is: a kind of Chinese medicine composition of treating myocardial infarction is provided, and it can make in a short time that after patient's medication the symptom that is caused by myocardial infarction is eased, and reaches the effect that symptom takes place that delays; And make that the patient of this disease is evident in efficacy after taking this medicine.
Another object of the present invention has provided the method for preparing of this Chinese medicine composition.
The objective of the invention is to realize that through following proposal a kind of Chinese medicine composition of treating myocardial infarction is characterized in that: this medicine is formulated by the raw material of Chinese medicine medicine of following portions by weight:
Gekko Swinhonis 13-50 part, Maifanitum 50-100 part, Radix Salviae Miltiorrhizae 30-50 part, Radix Astragali 50-100 part, Radix Et Rhizoma Rhei 15-50 part, Rhizoma Chuanxiong 15-30 part, Radix Achyranthis Bidentatae 15-30 part, Radix Paeoniae Rubra 15-50 part, Radix Angelicae Sinensis 10-30 part, Radix Rehmanniae 18-50 part, Rhizoma Et Radix Notopterygii 18-50 part, windproof 15-30 part, Moschus 1-10 part, Rhizoma Cyperi 10-30 part, Folium Perillae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Rhizoma Corydalis 10-20 part.
Described a kind of Chinese medicine composition optimum weight part of treating myocardial infarction is:
30 parts of Gekko Swinhonis, 75 parts of Maifanitums, 38 parts of Radix Salviae Miltiorrhizaes, 75 parts of the Radixs Astragali, 30 parts of Radix Et Rhizoma Rhei, 23 parts of Rhizoma Chuanxiongs, 23 parts of Radix Achyranthis Bidentataes, 32 parts of Radix Paeoniae Rubra, 20 parts of Radix Angelicae Sinensis, 26 parts in the Radix Rehmanniae, 34 parts of Rhizoma Et Radix Notopterygiis, windproof 23 parts, 5 parts in Moschus, 20 parts of Rhizoma Cyperis, 15 parts of Folium Perillaes, 15 parts of Pericarpium Citri Reticulataes, 16 parts of Rhizoma Corydalis.
A kind of method for preparing of treating the Chinese medicine composition of myocardial infarction may further comprise the steps:
1), takes by weighing raw material: Gekko Swinhonis 13-50 part, Maifanitum 50-100 part, Radix Salviae Miltiorrhizae 30-50 part, Radix Astragali 50-100 part, Radix Et Rhizoma Rhei 15-50 part, Rhizoma Chuanxiong 15-30 part, Radix Achyranthis Bidentatae 15-30 part, Radix Paeoniae Rubra 15-50 part, Radix Angelicae Sinensis 10-30 part, Radix Rehmanniae 18-50 part, Rhizoma Et Radix Notopterygii 18-50 part, windproof 15-30 part, Moschus 1-10 part, Rhizoma Cyperi 10-30 part, Folium Perillae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Rhizoma Corydalis 10-20 part according to following portions by weight;
2), get the Maifanitum, Radix Salviae Miltiorrhizae, the Radix Astragali, Radix Et Rhizoma Rhei, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Paeoniae Rubra, Radix Angelicae Sinensis, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii of above-mentioned weight portion, windproof, Moschus, Rhizoma Cyperi, Folium Perillae, Pericarpium Citri Reticulatae, Rhizoma Corydalis; Twice of decocte with water; For the first time add 5 times of amounts of water, 80～95 ℃ of heating-up temperatures decocted 40～60 minutes; For the second time add 3 times of amounts of water, decocted 40～60 minutes, merge decoction liquor twice, filter, be concentrated into 1/3rd of stock solution weight, natural cooling, subsequent use;
3), Gekko Swinhonis 13-50 part in the above-mentioned prescription dried the back pulverize, add step 2) in stir in the concentrated solution after, continue to decoct 30 minutes in 80～95 ℃, filter, it is the thick paste of 1.20-1.25 at 60 ℃, relative density that filtrate decompression is concentrated into temperature;
4) with 3) 75～85 ℃ of dryings of thick paste after, pulverized 120 mesh sieves, fine powder, mixing is processed described Chinese medicine composition.
Described Chinese medicine composition can be processed capsule or granule or tablet or oral liquid.
The instructions of taking of capsule of the present invention: it is 0.2g that capsule (0.2g/ grain) contains active ingredient; Adopt twice each 1-2 grain every day, use warm boiled water, 7 days courses of treatment.
The instructions of taking of granule of the present invention: it is 0.4g that granule (0.4g/ bag) contains active ingredient; Adopt each one bag of twice of every day, use warm boiled water, 7 days courses of treatment.
The instructions of taking of tablet of the present invention: it is 0.2g that tablet (0.2g/ sheet) contains active ingredient; Adopt each two of twice of every day, use warm boiled water, 7 days courses of treatment.
The instructions of taking of oral liquid of the present invention: oral liquid is 7 days courses of treatment, takes twice every day, each 350ml～500ml.
The present invention selects Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii to carry out compatibility, makes to produce synergism behind these drug regimens, the sequela that can more effectively treat myocardial infarction, coronary heart disease and cause because of myocardial infarction, myocardial infarction.Wherein, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong have, promoting blood circulation to restore menstrual flow, blood circulation promoting and blood stasis dispelling, enriching yin and nourishing kidney, liver and kidney tonifying, the promoting blood circulation that relaxes, eliminating stasis to stop pain detumescence life, the effect of functions dispelling wind and clearing away cold, removing dampness.
The present invention selects Radix Angelicae Sinensis, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii to carry out compatibility, such medicine has that granulation promoting is enriched blood, hemopoietic reinforcing the heart, tonifying Qi and lifting yang, consolidate promote the production of body fluid, the effect of powder detoxifcation, yin nourishing removing heat from blood, enhance immunity.
The present invention selects Maifanitum, Radix Et Rhizoma Rhei, the Radix Astragali to carry out compatibility, wherein, adopts the Radix Astragali to carry out compatibility, and this medicine is main with tonify deficiency, be usually used in asthenia with the passing of time, low, the thready pulse without strength person of speech.Radix Astragali tool is mended and oiliness characteristics, with medicine compatibility better effects if such as Radix Et Rhizoma Rhei.Radix Et Rhizoma Rhei has expelling wind and removing dampness, eliminating blood stasis and inducing menstruation, separates muscular spasm, the relieving constipation diuretic, the only effect of numbness of dispeling the wind.Can play with above-mentioned drug matching that granulation promoting is enriched blood, tonifying Qi and lifting yang, consolidate promote the production of body fluid, the effect of powder detoxifcation, enhance immunity.Windproof expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion; The Moschus refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving, Rhizoma Cyperi and the Rhizoma Corydalis resolving depression of regulating the flow of vital energy, pain relieving; Pericarpium Citri Reticulatae, the ability spleen invigorating can be regulated the flow of vital energy again, makes so often be used as the assistant of Qi-tonifying drug, can make tonify without causing stagnation, prevents to stop up to hold back to do to expand to act on.
The present invention selects Gekko Swinhonis to carry out compatibility, and this medicine has tonifying the lung kidney, benefiting essence-blood, relieving cough and relieving asthma, spasmolytic is dispeled the wind and disperse the repercussive effect, and Gekko Swinhonis also has convulsion and haemolysis, is used for paralysis due to windstroke, and the treatment of rheumatic arthritis is particularly effective.
It is a kind of natural medicine Ore that the present invention selects Maifanitum; Contain 18 kinds of trace element such as the necessary potassium of human body, sodium, calcium, magnesium, phosphorus macroelement and zinc, ferrum, selenium, copper, strontium, iodine, fluorine, metasilicic acid; It has YIN and YANG balance regulating, strengthens opposing, improves immunity; Vessel softening, the effect of dredging the meridian.
The present invention is used for myocardial infarction complication patient's the prophylactic treatment and the treatment in morbidity later stage.Patient's concurrent atheromatous plaque on the basis of pathological changes of suffering from long-term coronary atherosclerosis disease breaks, thrombosis in hemorrhage, the lumen of vessels; Endarterium bleed bottom or tremulous pulse fixed spasm; When making the rapid generation of tube chamber inaccessible lastingly and completely; Originally fully do not set up the serious lasting ischemia of the cardiac muscle that can cause this tremulous pulse to be supplied like side Zhi Xunhuan between this tremulous pulse and other coronary artery.The present invention is intended to dredge patient vessel's passage, vessel softening, and reaching brings high blood pressure down prevents thrombotic purpose.
The present invention couple and clinical manifestation are that uncomfortable in chest, nervous, symptoms such as weak breath is unable, numb limbs and tense tendons, hemiplegia, arrhythmia have obvious effect; The present invention has no side effect; And have promoting blood circulation to restore menstrual flow, the liver and the kidney tonifying, pain relieving granulation promoting, analgesic soothing the liver, effect that warming the meridian is dredged sun, clearing heat and moistening dryness; For the patient of myocardial infarction and sequela thereof, after taking the present invention, has the situation of obvious alleviation disease after two to three courses of treatment.
The specific embodiment
Below in conjunction with the specific embodiment the present invention is further specified, need to prove that following embodiment only is used to explain the present invention, is not limited to practical range of the present invention.
Embodiment 1
Get Gekko Swinhonis 30g, Maifanitum 75g, Radix Salviae Miltiorrhizae 38g, Radix Astragali 75g, Radix Et Rhizoma Rhei 30g, Rhizoma Chuanxiong 23g, Radix Achyranthis Bidentatae 23g, Radix Paeoniae Rubra 32g, Radix Angelicae Sinensis 20g, Radix Rehmanniae 26g, Rhizoma Et Radix Notopterygii 34g, windproof 23g, Moschus 5g, Rhizoma Cyperi 20g, Folium Perillae 15g, Pericarpium Citri Reticulatae 15g, Rhizoma Corydalis 16g.
Get the Maifanitum, Radix Salviae Miltiorrhizae, the Radix Astragali, Radix Et Rhizoma Rhei, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Paeoniae Rubra, Radix Angelicae Sinensis, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii of above-mentioned weight portion, windproof, Moschus, Rhizoma Cyperi, Folium Perillae, Pericarpium Citri Reticulatae, Rhizoma Corydalis; Twice of decocte with water; Add for the first time 5 times of amounts of water; 80～95 ℃ of heating-up temperatures (85 ℃ is best) decoct 40～60 minutes (50 minutes is best); For the second time add 3 times of amounts of water, decocted 40～60 minutes, merge decoction liquor twice, filter, be concentrated into 1/3rd of stock solution weight, natural cooling, subsequent use; Gekko Swinhonis 30g in the above-mentioned prescription is dried the back pulverizes, add stir in the above-mentioned subsequent use concentrated solution after, continue to decoct 30 minutes in 80～95 ℃, filter, it is the thick paste of 1.20-1.25 at 60 ℃, relative density that filtrate decompression is concentrated into temperature; After 75～85 ℃ of dryings of thick paste, pulverized 120 mesh sieves, get fine powder, mixing is processed described Chinese medicine composition.Dextrin and magnesium stearate that described Chinese medicine composition adding is an amount of carry out always mixing, total encapsulated capsule that promptly gets in back that mixes.
The instructions of taking of capsule of the present invention: it is 0.2g that capsule (0.2g/ grain) contains active ingredient; Adopt twice each 1-2 grain every day, use warm boiled water, 7 days courses of treatment.
Embodiment 2
Get Gekko Swinhonis 13g, Maifanitum 50g, Radix Salviae Miltiorrhizae 30g, Radix Astragali 50g, Radix Et Rhizoma Rhei 15g, Rhizoma Chuanxiong 15g, Radix Achyranthis Bidentatae 15g, Radix Paeoniae Rubra 15g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 18g, Rhizoma Et Radix Notopterygii 18g, windproof 15g, Moschus 1g, Rhizoma Cyperi 10g, Folium Perillae 10g, Pericarpium Citri Reticulatae 10g, Rhizoma Corydalis 10g.
Method for preparing is with embodiment 1, and difference is: described Chinese medicine composition is added an amount of dextrin carry out always mixing with magnesium stearate, always mix the back tabletting, wrap film-coat and promptly get tablet.
The instructions of taking of tablet of the present invention: it is 0.2g that tablet (0.2g/ sheet) contains active ingredient; Adopt each two of twice of every day, use warm boiled water, 7 days courses of treatment.
Embodiment 3
Get Gekko Swinhonis 50g, Maifanitum 100g, Radix Salviae Miltiorrhizae 50g, Radix Astragali 100g, Radix Et Rhizoma Rhei 50g, Rhizoma Chuanxiong 30g, Radix Achyranthis Bidentatae 30g, Radix Paeoniae Rubra 50g, Radix Angelicae Sinensis 30g, Radix Rehmanniae 50g, Rhizoma Et Radix Notopterygii 50g, windproof 30g, Moschus 10g, Rhizoma Cyperi 30g, Folium Perillae 30g, Pericarpium Citri Reticulatae 30g, Rhizoma Corydalis 20g.
Method for preparing is with embodiment 1, and difference is: dextrin and magnesium stearate that described Chinese medicine composition adding is an amount of carry out always mixing, and total back adding correctives that mixes is processed oral liquid.
The instructions of taking of oral liquid of the present invention: oral liquid is 7 days courses of treatment, takes twice every day, each 350ml～500ml.
Embodiment 4
Gekko Swinhonis 25g, Maifanitum 75g, Radix Salviae Miltiorrhizae 35g, Radix Astragali 65g, Radix Et Rhizoma Rhei 30g, Rhizoma Chuanxiong 25g, Radix Achyranthis Bidentatae 25g, Radix Paeoniae Rubra 40g, Radix Angelicae Sinensis 20g, Radix Rehmanniae 38g, Rhizoma Et Radix Notopterygii 38g, windproof 20g, Moschus 5g, Rhizoma Cyperi 20g, Folium Perillae 20g, Pericarpium Citri Reticulatae 20g, Rhizoma Corydalis 15g.
Method for preparing is with embodiment 1, and difference is: dextrin and magnesium stearate that described Chinese medicine composition adding is an amount of carry out always mixing, and process granule after total the mixing.
The instructions of taking of granule of the present invention: it is 0.4g that granule (0.4g/ bag) contains active ingredient; Adopt each one bag of twice of every day, use warm boiled water, 7 days courses of treatment.
Said ratio is not limited only to prepare said dosage form, can also take a kind of other dosage form of proportioning preparation, is not limited only to prepare capsule like embodiment 1 said proportioning, can also prepare granule, tablet, oral liquid etc.
In order to show the therapeutic effect of medicine of the present invention, the present invention has carried out the clinical observation test.The treatment group is taken the capsule that the embodiment of the invention 1 makes in the test on the basis of western medicine, and specification is every and contains active ingredient 0.2g.The matched group list is used western medicine.
Two groups of patients are the inpatient, all are cardinal symptom with the chest pain, totally 66 examples.Be divided into two groups at random.36 examples are organized in treatment, male 26 examples, women 10 examples, age 50-76 year, 63 years old mean age.Blocking part: antetheca 14 examples, lower wall 10 examples, preceding partition 4 examples, high sidewall 1 example, positive rear wall 1 example, above 6 examples in 2 places.Complication: arrhythmia 10 examples, heart failure 4 examples, cardiogenic shock 2 examples.Matched group 30 examples, male 22 examples, women 8 examples, 49 years old～75 years old age, 62 years old mean age, blocking part: antetheca 12 examples, lower wall 8 examples, preceding partition 2 examples, positive rear wall 1 example, 2 places above infraction 7 examples.Complication: arrhythmia 8 examples, heart failure 4 examples, cardiogenic shock 3 examples.At two groups of ages, state of an illness there was no significant difference has comparability.
Acute myocardial infarction diagnosis: 1) clinical symptoms typical case; 2) electrocardiogram have abnormal Q involve/ST-T has the differentiation that meets myocardial infarction; 3) sero-enzyme increases, and meets the process person of myocardial infarction.
Therapeutic Method: two groups of patients all according to the AMI conventional therapy as lying up, oxygen uptake, morphine 3mg～5mg or pethidine 25mg～50mg intravenous injection is selected in pain relieving for use, duplicate injection after 15～30 minutes in case of necessity, but the time spent need monitor the variation of blood pressure and breathing; Quiet nitroglycerin begins from 50ug/min, increases dosage 5ug/min in per 5～10 minutes, removes or systolic pressure reduces and changes oral nitrate esters medicine into after being no more than 10%, 3～5 days until pain; Meeting thrombolytic standard (with reference to ACC and heart disease association 1991 annual reports) gives urokinase 1503 and is dissolved in the 100ml normal saline 30～60 minutes quiet.As merge arrhythmia or heart failure and shock person, rescue conventional treatment by doctor trained in Western medicine.
The matched group list is used western medicine, the treatment group on the basis of western medicine, oral capsule of the present invention, instructions of taking: it is 0.2g that capsule (0.2g/ grain) contains active ingredient; Every day, twice each 1-2 grain used warm boiled water, 7 days courses of treatment, observed 2～4 courses of treatment altogether.Observe every day and transference cure or improvement time such as record patient chest pain, all go Electrocardioscopy before the treatment, after this check electrocardiogram weekly 3～4 times.
Efficacy determination: produce effects: transference cure, electrocardiogram obviously improves;
Effectively: sx, electrocardiogram still have ischemia to change;
Invalid: cardinal symptom and electrocardiogram do not have change or sb.'s illness took a turn for the worse.
Therapeutic outcome: treatment group produce effects 20 examples (56%), effective 12 examples (33%), total effective rate 89%; Matched group produce effects 11 examples (37%), effective 13 examples (43%), total effective rate 80%.Treatment group total effective rate is superior to matched group; Though the two there was no significant difference (P＞0.05); But treatment group obvious effective rate (56%) and doing well,improving time (4-7 days) and matched group obvious effective rate (37%) and doing well,improving time (6-9 days) contrast, the two has significant difference (P＜0.05), sees attached list.
Table 1 medicine of the present invention and matched group Comparison of therapeutic:
In a word, effect of the present invention is remarkable, cost, and curative effect is short, instant effect, is a kind of highly effective medicine of treatment myocardial infarction.
Claims (4)
1. Chinese medicine composition of treating myocardial infarction, it is characterized in that: this medicine is formulated by the raw material of Chinese medicine medicine of following portions by weight:
Gekko Swinhonis 13-50 part, Maifanitum 50-100 part, Radix Salviae Miltiorrhizae 30-50 part, Radix Astragali 50-100 part, Radix Et Rhizoma Rhei 15-50 part, Rhizoma Chuanxiong 15-30 part, Radix Achyranthis Bidentatae 15-30 part, Radix Paeoniae Rubra 15-50 part, Radix Angelicae Sinensis 10-30 part, Radix Rehmanniae 18-50 part, Rhizoma Et Radix Notopterygii 18-50 part, windproof 15-30 part, Moschus 1-10 part, Rhizoma Cyperi 10-30 part, Folium Perillae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Rhizoma Corydalis 10-20 part.
2. according to the described a kind of Chinese medicine composition of treating myocardial infarction of claim 1, it is characterized in that: it is formulated by the raw material of Chinese medicine medicine of following portions by weight:
30 parts of Gekko Swinhonis, 75 parts of Maifanitums, 38 parts of Radix Salviae Miltiorrhizaes, 75 parts of the Radixs Astragali, 30 parts of Radix Et Rhizoma Rhei, 23 parts of Rhizoma Chuanxiongs, 23 parts of Radix Achyranthis Bidentataes, 32 parts of Radix Paeoniae Rubra, 20 parts of Radix Angelicae Sinensis, 26 parts in the Radix Rehmanniae, 34 parts of Rhizoma Et Radix Notopterygiis, windproof 23 parts, 5 parts in Moschus, 20 parts of Rhizoma Cyperis, 15 parts of Folium Perillaes, 15 parts of Pericarpium Citri Reticulataes, 16 parts of Rhizoma Corydalis.
3. method for preparing of treating the Chinese medicine composition of myocardial infarction may further comprise the steps:
1), takes by weighing raw material: Gekko Swinhonis 13-50 part, Maifanitum 50-100 part, Radix Salviae Miltiorrhizae 30-50 part, Radix Astragali 50-100 part, Radix Et Rhizoma Rhei 15-50 part, Rhizoma Chuanxiong 15-30 part, Radix Achyranthis Bidentatae 15-30 part, Radix Paeoniae Rubra 15-50 part, Radix Angelicae Sinensis 10-30 part, Radix Rehmanniae 18-50 part, Rhizoma Et Radix Notopterygii 18-50 part, windproof 15-30 part, Moschus 1-10 part, Rhizoma Cyperi 10-30 part, Folium Perillae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Rhizoma Corydalis 10-20 part according to following portions by weight;
2), get the Maifanitum, Radix Salviae Miltiorrhizae, the Radix Astragali, Radix Et Rhizoma Rhei, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Paeoniae Rubra, Radix Angelicae Sinensis, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii of above-mentioned weight portion, windproof, Moschus, Rhizoma Cyperi, Folium Perillae, Pericarpium Citri Reticulatae, Rhizoma Corydalis; Twice of decocte with water; For the first time add 5 times of amounts of water, 80～95 ℃ of heating-up temperatures decocted 40～60 minutes; For the second time add 3 times of amounts of water, decocted 40～60 minutes, merge decoction liquor twice, filter, be concentrated into 1/3rd of stock solution weight, natural cooling, subsequent use;
3), Gekko Swinhonis 13-50 part in the above-mentioned prescription dried the back pulverize, add step 2) in stir in the concentrated solution after, continue to decoct 30 minutes in 80～95 ℃, filter, it is the thick paste of 1.20-1.25 at 60 ℃, relative density that filtrate decompression is concentrated into temperature;
4) with 3) 75～85 ℃ of dryings of thick paste after, pulverized 120 mesh sieves, fine powder, mixing is processed described Chinese medicine composition.
4. according to the described a kind of Chinese medicine composition of treating myocardial infarction of claim 1, it is characterized in that: described Chinese medicine composition can be processed capsule or granule or tablet or oral liquid.
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| CN2010106215070A CN102526412A (en) | 2010-12-20 | 2010-12-20 | Chinese medicine composition for treating myocardial infarction |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272175A (en) * | 2013-05-28 | 2013-09-04 | 高志芳 | Traditional Chinese medicine for treating myocardial infarction and preparation method thereof |
| CN104306639A (en) * | 2014-11-07 | 2015-01-28 | 李艳琴 | Traditional Chinese medicine preparation for treating myocardial infarction and preparation method thereof |
-
2010
- 2010-12-20 CN CN2010106215070A patent/CN102526412A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272175A (en) * | 2013-05-28 | 2013-09-04 | 高志芳 | Traditional Chinese medicine for treating myocardial infarction and preparation method thereof |
| CN104306639A (en) * | 2014-11-07 | 2015-01-28 | 李艳琴 | Traditional Chinese medicine preparation for treating myocardial infarction and preparation method thereof |
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Application publication date: 20120704 |