CN102524872A - Ginseng peptide amino acid drink - Google Patents
Ginseng peptide amino acid drink Download PDFInfo
- Publication number
- CN102524872A CN102524872A CN2012100245832A CN201210024583A CN102524872A CN 102524872 A CN102524872 A CN 102524872A CN 2012100245832 A CN2012100245832 A CN 2012100245832A CN 201210024583 A CN201210024583 A CN 201210024583A CN 102524872 A CN102524872 A CN 102524872A
- Authority
- CN
- China
- Prior art keywords
- percent
- water
- essence
- ginseng
- ginseng peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Non-Alcoholic Beverages (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a ginseng peptide amino acid drink, which is prepared from the following raw materials in percentage by weight: 0.1 to 0.5 percent of total ginsenoside extract, 0.1 to 0.5 percent of corn oligopeptides, 0.1 to 0.2 percent of inositol, 0.15 to 0.2 percent of lysine, 0.15 to 0.2 percent of arginine, 0.15 to 0.2 percent of glycine, 0.05 to 0.15 percent of taurine, 8 to 12 percent of white granulated sugar, 10 to 20 percent of concentrated fruit juice, 0.015 to 0.02 percent of sodium carboxymethylcellulose, 0.15 to 0.3 percent of citric acid, 0.1 to 0.2 percent of sodium citrate, 0.07 to 0.1 percent of beta-cyclodextrine, 0.1 to 0.2 percent of essence and the balance of pure water. The extraction method of the total ginsenoside extract comprises: grinding ginseng into fine powder, soaking the fine ginseng powder in water, stirring the mixture intermittently, filtering the mixture, loading the filtrate onto a macroporous absorption resin column, washing the macroporous absorption resin column with water after absorption till the effluent is clear, washing the macroporous absorption resin column with water containing alkaline inorganic detergent till the effluent is clear, washing the macroporous absorption resin column with water till the pH value is 5 to 7, eluting by using ethanol, collecting eluent, concentrating the eluent and drying.
Description
Technical field
The present invention relates to a seed ginseng peptide ammino acid beverage.
Background technology
Along with the quickening of modern life rhythm, the aggravation of social competition, survival pressure strengthens, and fatigue becomes the health problem of puzzlement much human.Health food with alleviating fatigue effect arises at the historic moment.Fatigue is a kind of physiological phenomenon, is a kind of mechanism of protectiveness to the people.This is that health sends the signal that have a rest to us.If a kind of beverage of alleviating fatigue can be arranged, must receive people's welcome.
Summary of the invention
Task of the present invention is to provide a seed ginseng peptide ammino acid beverage exactly, and the present invention implements through following technical scheme:
Ginseng peptide ammino acid beverage of the present invention presses that column weight amount percentage range proportion raw material processes: TSPG extract 0.1～0.5%, corn oligopeptide 0.1～0.5%, inositol 0.1～0.2%; Lysine 0.15～0.2%, arginine 0.15～0.2%, glycine 0.15～0.2%; Taurine 0.05～0.15%, white granulated sugar 8～12%, inspissated juice 2～10%; Sodium carboxymethylcellulose 0.015～0.02%, citric acid 0.15～0.3%, natrium citricum 0.1～0.2%; Cycloheptaamylose 0.07～0.1%, flavoring essence 0.1～0.15%, all the other are pure water.
The method for distilling of above-mentioned TSPG extract is such: get the ginseng pulverate and be broken into fine powder, be soaked in water, stir frequently, filter; Filtrating is through the macroporous absorbent resin post, and absorption finishes, and is washed with water to flow out the liquid clarification, washs with the water that contains alkaline inorganic washing agent again; To the eluate clarification, be washed with water to the pH value again for 5-7, use ethanol elution instead, collect eluent; Concentrate, drying promptly gets above-mentioned TSPG extract.
Ginseng peptide ammino acid method for preparing beverage of the present invention is: with sterilized water white granulated sugar is dissolved, heats; And under 90-95 ℃, be incubated 10-15 minute; Guarantee that syrup is aseptic, squeeze into blend tank then, sodium carboxymethylcellulose is squeezed into blend tank after milling treatment of colloid; Squeezing into blend tank after TSPG extract and above-mentioned other raw material dissolvings stirs; Through getting into the superhigh temperature flash pasteurizer after the assay was approved, sterilization between 125～130 ℃ after 10 seconds at 88～90 ℃ of following cans, cooling packings then.
With prior art relatively, TSPG method for distilling of the present invention is a kind of method of innovation, it has produced very good effect: energy savings greatly makes that total saponin content improves greatly in the extract; The present invention simultaneously chooses multiple materials such as corn oligopeptide powder, inositol, lysine, arginine, taurine; The composition of Chinese and western drugs is effectively combined, and the beverage of making has alleviating physical fatigue and function of health care, and because the present invention has added the fruit juice of various tastes; Make this beverage can satisfy the consumption demand of different crowd; Taste is sweet and tasty, and is changeable, can satisfy different consumers' selection needs; Make this product have vast market prospect.
The specific embodiment
Below further specify the present invention for example, and come further summary beneficial effect of the present invention through Test Example.
Ginseng peptide ammino acid beverage of the present invention is pressed column weight amount percentage range proportion raw material and is processed: TSPG extract 0.1～0.5%, corn oligopeptide 0.1～0.5%, inositol 0.1～0.2%; Lysine 0.15～0.2%, arginine 0.15～0.2%, glycine 0.15～0.2%; Taurine 0.05～0.15%, white granulated sugar 8～12%, inspissated juice 2～10%; Sodium carboxymethylcellulose 0.015～0.02%, citric acid 0.15～0.3%, natrium citricum 0.1～0.2%; Cycloheptaamylose 0.07～0.1%, essence 0.1～0.15%.All the other are pure water.
The method for distilling of above-mentioned TSPG extract is: get the ginseng pulverate and be broken into fine powder, be soaked in water, stir frequently, filter; Filtrating is through the macroporous absorbent resin post, and absorption finishes, and is washed with water to flow out the liquid clarification, washs with the water that contains alkaline inorganic washing agent again; To the eluate clarification, be washed with water to the pH value again for 5-7, use ethanol elution instead, collect eluent; Concentrate, drying promptly gets the TSPG extract.
Ginseng peptide ammino acid method for preparing beverage of the present invention is: with sterilized water white granulated sugar is dissolved, heats; And under 90-95 ℃, be incubated 10-15 minute; Guarantee that syrup is aseptic, squeeze into blend tank then, sodium carboxymethylcellulose is squeezed into blend tank after milling treatment of colloid; Squeezing into blend tank after TSPG extract and above-mentioned other raw material dissolvings stirs; Through getting into the superhigh temperature flash pasteurizer after the assay was approved, sterilization between 125～130 ℃ after 10 seconds at 88～90 ℃ of following cans, cooling packings then.
Above-mentioned inspissated juice can be any one or a few in cider or guava juice or peach juice or mango juice or the passion fruit juice.
Above-mentioned essence is the essence corresponding with said fruit juice.
Embodiment 1
Ginseng peptide ammino acid beverage of the present invention presses that column weight amount percentage range proportion raw material processes: TSPG extract 0.15%, corn oligopeptide 0.1%, inositol 0.1%, lysine 0.2%; Arginine 0.1%, glycine 0.2%, taurine 0.1%, white granulated sugar 8%; Apple inspissated juice 20%, sodium carboxymethylcellulose 0.02%, citric acid 0.28%; Natrium citricum 0.15%, cycloheptaamylose 0.07%, flavoring apple essence 0.1%.All the other are pure water.
The method for distilling of above-mentioned TSPG extract is: get the ginseng pulverate and be broken into fine powder, be soaked in water, stir frequently, filter; Filtrating is through the macroporous absorbent resin post, and absorption finishes, and is washed with water to flow out the liquid clarification, washs with the water that contains alkaline inorganic washing agent again; To the eluate clarification, be washed with water to the pH value again for 5-7, use ethanol elution instead, collect eluent; Concentrate, drying promptly gets the TSPG extract.
Said essence is apple flavor essence.
Described ginseng peptide ammino acid method for preparing beverage is: with sterilized water white granulated sugar is dissolved, heats, and be incubated 10-15 minute down at 90-95 ℃, guarantee that syrup is aseptic; Squeeze into blend tank then; Sodium carboxymethylcellulose is squeezed into blend tank after milling treatment of colloid, squeeze into blend tank after TSPG extract and above-mentioned other raw material dissolvings and stir, and gets into the superhigh temperature flash pasteurizer through after the assay was approved; Sterilization between 125～130 ℃ after 10 seconds at 88～90 ℃ of following cans, cooling packings then.
Embodiment 2
Ginseng peptide ammino acid beverage of the present invention is pressed column weight amount percentage range proportion raw material and is processed;
TSPG extract 0.2%, corn oligopeptide 0.2%, inositol 0.2%, lysine 0.2%; Arginine 0.1%, glycine 0.2%, taurine 0.15%, white granulated sugar 10%; Honey peach fruit juice 20%, sodium carboxymethylcellulose 0.02%, citric acid 0.3%; Natrium citricum 0.2%, cycloheptaamylose 0.1%, honey peach essence 0.15%.All the other are pure water.
The method for distilling of described TSPG extract is with embodiment 1.Said essence is honey peach flavor essence.
Described ginseng peptide ammino acid method for preparing beverage is with embodiment 1.
The above is merely embodiments of the invention, and all equivalent variations and modifications of doing according to claim of the present invention all should belong to protection covering scope of the present invention.
Technical scheme of the present invention is based on motherland's medical science, with reference to modern pharmacological research, from the Chinese medicine treasure-house, filters out natural edible-plant, and by the screening that theory of traditional Chinese medical science is filled a prescription, the concrete effect brief introduction of each raw material that the present invention selected for use is following:
1. ginseng extract is the material that contains functional components such as saponin(e that from panax ginseng plant, extracts.It has following effect:
1) strengthen central nervous system function: the saponin in the genseng can effectively strengthen nervous centralis, reach with all worries set aside with fixed attention, eliminate effects such as fatigue, enhance memory power, applicable to insomnia, agitation, be losing one's memory and symptom such as senile dementia.
2) protection cardiovascular system: the informal dress genseng can anti-arrhythmia, resisting myocardial ischemia, anti-myocardium oxidation, strengthen cardiac contractility ability, and the patients with coronary heart disease symptom shows as deficiency of both qi and yin, nervously breathes hard and can take American Ginseng for a long time, and is evident in efficacy.Efficacy of American ginseng also is to regulate blood pressure, can effectively reduce temporary and the persistence blood pressure, helps the recovery of diseases such as hypertension, arrhythmia cordis, coronary heart disease, acute myocardial infarction, cerebral thrombus.
3) improve immunity; Genseng is as the first-selected medicinal material of qi-tonifying health-care, can promote that haemocyanin is synthetic, bone marrow protein is synthetic, organ albumen is synthetic etc., improves immunity of organisms, suppresses growth of cancer cells, the opposing cancer.
4) promote the blood vigor: long clothes genseng can reduce blood clotting property, suppresses platelet aggregation, antiatherosclerosis and promote the red blood cell growth, increases hemochrome.
5) can reduce blood sugar, adjusting insulin secretion, promotion glycometabolism and fat metabolism, the treatment diabetes are had certain booster action.
2. corn peptide is a wholefood, is the protein that from corn, extracts, the micromolecule polypeptide material that the process pacemaker enzyme is cut and specific little peptide isolation technics obtains again.It has following effect:
1) protection liver: during the amino acid of corn peptide is formed; Branched-chain amino acid (leucine, isoleucine, valine) content is very high, and report is arranged, and the branched-amino acid content descends in hepatic coma, the hepatic encephalopathy patient's blood; Input high-load branched-chain amino acid can make the state of an illness be eased; High branched-chain amino acid abundant in the corn peptide has liver protection effect, and to the liver damage that alcohol causes, fatty liver etc. can play prevention effect.Experiment proof corn peptide all has the significant protection effect to the hepatic injury that number of chemical materials such as carbon tetrachloride, thioacetamide, alcohol cause.In addition, show that corn peptide more can obviously alleviate the sex change of liver cell fat, obviously improve the liver tissue injury degree, so corn peptide has important protective effect to liver according to pathological examination.
2) the unique amino acid of corn peptide constitutes, and helps promoting alcohol metabolism: take in the interior alcohol of body after stomach absorbs, mainly metabolism in liver.Alanine, leucine are the key amino acids relevant with alcohol metabolism.Alanine can promote the decomposition of alcohol in the blood, strengthens the effect of liver function, liver protecting.Leucine can alleviate the symptom that causes anthropochemistry reaction imbalance because of alcohol, and helps to control alcoholism.Take in the generation that alcohol can suppress glutamic acid.And glutamic acid can be participated in the albumen and the glycometabolism of brain, and accelerating oxidation improves the nervous centralis activity, keeping is arranged and promote the effect of function of brain cell.
Corn peptide has sobering-up functions, because wherein contain a high proportion of alanine and leucine.Take in after the corn peptide; Through improving alanine and leucic concentration in the blood; Can produce the codehydrogenase of stable decomposition ethanol, strengthen the activity of L-AD and acetaldehyde dehydrogenase, promote the decomposition and the metabolism of ethanol in the body; Thereby reduce the concentration of ethanol in blood, reach and reduce drunk degree and the effect of sobering up.
Simultaneously, contain abundant glutamic acid in the corn peptide, take in corn peptide, can supplemental blood in because of receiving alcohol to suppress the amino acid that reduces, thereby keep the energy supply and the nervous activity of brain cell, the neurological symptom that minimizing alcohol causes.
3) anti-oxidant: corn peptide has the antioxidation of similar SOD (superoxide dismutase), and ultra-oxygen anion free radical and hydroxyl radical free radical are had strong scavenging action.Therefore corn peptide not only has protective effect to liver, can also improve the oxidation resistance of health, helps human body to delay the aging of health from inside to outside.
4) hypotensive: corn peptide can suppress the activity of Angiotensin-Converting, and the competitive inhibitor as a kind of angiotensins alleviates vascular tone, produces hypotensive effect, and normotensive people is not had effect.
5) enhance immunity and enhancement movement: glutamine content is very high in the amino acid whose composition of corn peptide; Glutamine and tissue growth, repair closely related; Improving immunity of organisms, keeping intestinal mucosa normal configuration and function, the ability that improves the extraneous destructive stimulus of organism adaptation all has important value.In addition owing to contain abundant leucine in the corn peptide, and absorb and to be exceedingly fast, therefore can be rapidly for the muscle of human body kinematic system and organ provide energy, so have the function of the locomitivity of enhances human body.
6) be prone to absorb: be superior to the absorption of amino acid or protein.
7) dissolubility: water-soluble fully under PH on a large scale, no turbid phenomenon and sediment produce.
8) stability: to thermally-stabilised, component does not change, and function is not lost.
9) security wholefood albumen is safe and reliable, has no side effect.
3 inositols are a kind of " bioses "; Participate in the metabolic activity in the body, have multiple effects such as some disease of immunity, prevention and treatment, inositol still is the growth factor of certain micro-organisms in the intestines; When other hypovitaminosis, it can stimulate the microorganism synthetic vitamin that is deficient in vitamin.
4 lysines: lysine is alkaline essential amino acid; In recent years, scientist finds that L-lysine is that the important substance of control people bulk-growth presses down long plain (Somatotation; Ss) most important in also is the most essential composition, and people's nervous centralis and peripheral nervous system all played an important role.Human body can not self synthesize L-lysine, must from food, draw.Lysine is the key substance that helps other nutriment fully to be absorbed and utilize by human body, and human body has only and replenished absorption and the utilization that enough L-lysine could improve food protein, reaches balanced nutritious, promotes to grow.Its effect has:
1) raising intelligence, promotion are grown, are built up health.
2) improve a poor appetite, improve malnutritive situation.
3) improve insomnia, improve memory.
4) help to produce antibody, hormone and enzyme, improve immunity, increase hemochrome.
5) absorption of help calcium, treatment prevents osteoporosis
6) level of triglycerides in the reduction blood, the generation of prevention cardiovascular and cerebrovascular disease.
5. arginine is a constituent in the ornithine circulation, has extremely important physiological function.
1) increases the activity of arginase in the liver: help the ammonia in the blood is changed into urea and excretes out.So arginine quite produces effect to diseases such as hyperammonemia, liver dysfunctions.
2) arginine is a kind of double-basis amino acid, though concerning the adult, be nonessential amino acid, in some situation such as body development is immature or under serious stressed condition, if lack arginine, just body can not be kept positive nitrogen equilibrium and normal physiological function.
3) arginic important metabolic function is the healing effect that promotes wound, and it can promote the synthetic of collagen tissue, so can repair wound.In the wound juice, can be observed the active rising of arginase, this shows that also near the arginine requirement the wound heightens.Arginine can promote the microcirculation of wound circumference and impel wound to fully recover early.
4) arginic immunoloregulation function can prevent the degeneration (degeneration after especially injured) of thymus gland, and additional arginine can increase the weight of thymus gland, promotes the growth of thymus gland medium size lymphocyte.
5) replenish the volume that arginine can also reduce tumor-bearing animal, reduce the rate of transform of tumour, improve Survival Time and the survival rate of animal.In immune system, except that lymphocyte, cytophagous vigor is also relevant with arginine.After adding arginine, but its enzyme system of activation, and making it more can the kill tumor cell or target cell such as bacterium.
6. glycine is that organism constitutes one of amino acid in required 20, and getting side-chain radical is hydrogen, does not have optically active, is the simplest amino acid of structure in 20 seed amino acids, contains a large amount of glycine in the collagen.
1) glycine has unique sweet taste, can relax acid, alkali flavor, covers and adds the bitter taste of asccharin in the food and strengthen sweet taste.Human body is too much if take in the amount of glycine, and the utilization that not only can not be absorbed by the body, and can break human body amino acid whose absorption equilibrium is influenced other amino acid whose absorption causes nutrient imbalance and unhealthful.With the glycine is the milk-contained drink of main material production, teenager and children's normal growth is grown be easy to deleterious impact.
6. taurine
1) promote infant brain tissue and intelligence development: the content of taurine in brain is abundant, distribution is extensive, can obviously promote neural growing and cell proliferation, differentiation, and be dose dependent, in the cranial nerve cell growth course, plays an important role.
2) improve nerve conduction and visual function.
3) prevent cardiovascular disease: taurine can suppress platelet aggregation in the circulatory system, reduces blood fat, keeps the human body normal arterial pressure and prevents artery sclerosis; The cardiac muscle cell there is protective effect, but anti-arrhythmia; Cholesterol level has special efficacy in the blood to reducing, and can treat heart failure.
4) effect of taurine is to combine with bile acid to form cholyltaurine in the liver, and taurocholate is essential to the absorption of lipid in the alimentary canal.Taurocholate can increase the dissolubility of lipid and cholesterol, removes cholestasia, reduces the cytotoxicity of some free bile acid, suppresses the formation of cholesterol stone, increases bile flow etc.
5) improve endocrinosity, enhances human body immunity: taurine can promote the pituitrin secretion, the activation pancreas function, thereby improve the state of organism endocrine system, to organism metabolism with useful adjusting; And have the enhancing that promotes organism immunity and an effect of antifatigue.
6) taurine can combine with insulin receptor, promotes cellular uptake and utilizes glucose, quickens glycolysis, reduces blood sugar concentration.Research shows that taurine has certain hypoglycemic activity, and does not rely on the release that increases insulin.The glycometabolic regulating action of taurine pair cell possibly realize that it mainly relies on the interaction with insulin receptor protein through mechanism behind the acceptor, rather than direct and pancreas islet receptors bind.
7) suppress cataractous incidence and development: taurine has regulates crystal osmotic pressure and important function such as anti-oxidant; In cataract incidence and development process, sorbic acid content increases in the crystalline lens, and crystal osmotic pressure increases; Then obviously reduce as the important substance taurine concentration of regulating osmotic pressure; Antioxidation weakens, the protein generation over oxidation in the crystal, thus cause or increase the weight of cataractous generation.Supplementation of taurine can suppress cataractous incidence and development.
8) improve the function of remembering: find that in the animal experiment study of taurine and brain growth relation taurine can promote the learning and Memory ability of big white mouse.Replenish an amount of taurine and not only can improve learning and memory speed, but also can improve the accuracy of learning and memory, and to neural anti-ageing certain effect that also has.
9) keep normal reproductive function: normal reproductive function need be kept with taurine.
10) other functions: taurine is prevented and treated hypoferric anemia has positive effect, and it not only can promote the absorption of enteron aisle to iron, also can increase the stability of erythrocyte membrane; Taurine still is the short living factor of bifid bacterium in the human body intestinal canal, optimizes bacterial flora structure in the enteron aisle; Also has anti-oxidant, delaying senility function; Can promote oxyhepatitis to recover normal; Carbon tetrachloride poisoning there is protective effect, and can suppresses the rising of the caused thus serum paddy third special ammonia enzyme.Renal toxicity is had protective effect, and taurine changes the renal cells of former generation of the rabbit due to the cis-platinum has protective effect; Other has report, and taurine can be calm, analgesia and anti-inflammatory, and frostbite, KCN are poisoned and migraines also has preventive and therapeutic effect.
Below be some relevant experimental results that we carry out ginseng peptide ammino acid beverage of the present invention:
Test Example 1: animal function assessment testing data:
Test material: ginseng peptide ammino acid beverage of the present invention.
Test method:
1. adopt the method for antifatigue experiment regulation in " the health food function assessment assessment process and the method for inspection ", the effect of antifatigue under the checking 50ml/60Kg people .d dosage.
2. animal used as test: purchase a cleaning level kunming mice (male), 120, body weight 18-22g, sense environmental conditions, temperature range 20-25 ℃, relative humidity 40-70% from Central China University of Science and Technology's Experimental Animal Center.
3. experiment is divided into groups and the dosage selection
Animal adaptability was fed 3 days, weigh after 12 hours on an empty stomach, divide into groups immediately with reference to body weight.Experiment is divided into 4 groups, 10 times of groups of ginseng peptide ammino acid health beverages, and 20 times of groups are organized and control group for 30 times.To join the 10 times groups of peptide ammino acid health beverages by adult's RD (50ml/60Kg people * d), 20 times of groups, 30 times of concentrated wiring solution-formings are irritated stomach by the mouse body weight.Control group gives the equal long-pending distilled water that dissolves.Experiment was carried out 30 days altogether.
4. test test item and method
5% swimming test bears a heavy burden: get 40 of male mices, divide 4 groups at random, 10 every group; Sample 30d is given in design according to dosage continuously; 30min after last is irritated stomach binds the sheet lead that is equivalent to body weight 5% at the mouse tail root, puts into 25 ℃ ± 0.5 ℃ water; Force its swimming with a load attached to the body in the constant temperature water tank of depth of water 30cm, write down its swimming time from swimming beginning to death.
Blood lactic acid content: get 40 of male mices; Divide 4 groups at random, 10 every group, sample 30d is given in design according to dosage continuously; 30min after last is irritated stomach; Let it carry out the swimming exercise (water temperature is 25 ℃ ± 0.5 ℃) of 10min, adopt its tail blood and the centrifugal serum that gets behind the quiet 30min, survey its blood lactic acid content with the parazon method.
Hepatic glycogen content: get 40 of male mices, divide 4 groups at random, 10 every group, sample 30d is given continuously in design according to dosage, and 30min after last is irritated stomach kills it and gets its liver at once, freezing after 0.85% physiological saline processing.Detect its hepatic glycogen content with anthrone method.
Experimental result
5% antifatigue swimming test bears a heavy burden
The experimental data statistics is seen shown in the table 1.
Table 1 ginseng peptide ammino acid health beverages is to the antifatigue effect of 5% mouse swimming test that bears a heavy burden (X ± s)
| Control group | 10 times of groups of ginseng peptide | 20 times of groups of ginseng peptide | 30 times of groups of ginseng peptide | |
| Number of animals (only) | 10 | 10 | 10 | 10 |
| Swimming time (min) | 9.38±5.45 | 16.67±13.24 | 16.07±6.89 | 25.64±14.31 |
| The P value | 0.12 | 0.024* | 0.0035** |
Annotating * representes to compare with control group and has significant difference.* representes to compare with control group and has significant differences
The mouse 5% antifatigue swimming test statistical analysis of bearing a heavy burden shows; Irritate stomach 30d through giving mouse ginseng peptide ammino acid health beverages; Irritate stomach group 5% swimming time that bears a heavy burden and obviously all be longer than control group; And 20 times of groups of ginseng peptide and 30 times of groups of ginseng peptide significant difference have statistical significance, explain that tentatively this product has remarkable result to prolonging the mouse swimming time.
The blood lactic acid content
The experimental data statistics is seen shown in the table 2.
Table 2 ginseng peptide ammino acid health beverages is to the influence of mouse blood lactic acid content (X ± s)
Annotating: * representes to compare with control group and has significant difference.* representes to compare with control group and has significant differences
The statistical analysis as a result of ginseng peptide antifatigue mouse blood lactic acid content shows: the blood lactic acid content of three dose groups of high activity ginseng peptide all significantly is lower than control group; And check through t; All have statistical significance, explain that high activity ginseng peptide has remarkable result to the anti-fatigue ability that strengthens mouse.
Hepatic glycogen content
Table 3 ginseng peptide ammino acid health beverages is to the influence of Mouse Liver glycogen content (ml/100g mouse liver, X ± s)
| Control group | 10 times of groups of ginseng peptide | 20 times of groups of ginseng peptide | 30 times of groups of ginseng peptide | |
| Number of animals (only) | 10 | 10 | 10 | 10 |
| Hepatic glycogen content | 678.2±376.2 | 1036.3±205.2 | 1135.8±292.7 | 1255.4±553.4 |
| The P value | 0.0068* | 00045** | 0.012* |
Annotating: * representes to compare with control group and has significant difference.* representes to compare with control group and has the statistical analysis as a result of significant differences ginseng peptide ammino acid health beverages antifatigue Mouse Liver glycogen content and show: the hepatic glycogen content of three dose groups of ginseng peptide ammino acid beverage of the present invention all is significantly higher than control group; And check through t; All have statistical significance, explain that ginseng peptide ammino acid health beverages has remarkable result to the tolerance fatigue capability that strengthens mouse.
4. estimate:
Fatigue is the biochemical change procedure of body complex physical, is that the organism physiology process can not continue its function can not keep its predetermined exercise intensity at a specified level or organ.Owing to motion causes that the organism physiology biochemical change causes the temporarily-depressed phenomenon of body movement ability, be called sports type fatigue, antagonism muscle power (motion) fatigue comprises and delays physical fatigue generation and promote physical fatigue to eliminate two broad aspect.
The swimming time prolongation shows that exercise tolerance improves, and it is to delay physical fatigue to produce the most directly performance.What of the blood lactic acid content that the energetic supersession of motion back produces can react the organism fatigue degree to a certain extent: the blood lactic acid of generation is few more, and it is just strong more that the promotion muscle power fatigue of prompting animal is eliminated ability.Hepatic glycogen is an energy source main in the energetic supersession, and how much can reacting of animal self hepatic glycogen delays the ability that physical fatigue produces, and hepatic glycogen is many more, and the ability of animal tolerance fatigue is just strong more.
Through the statistical analysis to the data of the 5% antifatigue zoopery of bearing a heavy burden, blood lactic acid content, these three indexs of hepatic glycogen content, 20 times of groups of high activity ginseng peptide, 30 times are organized the experiment mice swimming with a load attached to the body time apparently higher than control group: hepatic glycogen content is apparently higher than control group; The blood lactic acid content is starkly lower than control group, and has statistical significance through the t check.
Therefore can conclusion according to antifatigue experimental result decision rule in " the health food function assessment assessment process and the method for inspection ": ginseng peptide ammino acid beverage of the present invention promotes the elimination of physical fatigue when having the generation that improves mouse anti-reflecting fatigue.
Test Example 2: animal toxicology testing data:
Test material: ginseng peptide ammino acid beverage of the present invention.
Ginseng peptide ammino acid beverage The acute toxicity tests of the present invention is MTD＞20.0g/kgbw (is equivalent to people's order recommended amounts 600 times), and according to the acute toxicity classification, these article belong to nontoxic level.
Mouse marrow cell micro nuclear test, mouse sperm distortion test, Salmonella reversion test result are all negative.Through 30 days feeding trials: fed 30 days to rat to be equivalent to 25,50,100 times of human body RD, duration of test, each treated animal vegetative activity is normal.When experiment finished, each dose groups the weight of animals of sample, weight gain, food-intake, food utilization, dirty body were than comparing the difference not statistically significant with control group.Sample part dose groups blood is biochemical, routine blood test index and control group comparison, and difference has statistical significance, but all in normal range (NR), the abiology meaning.Other each dose groups animal routine blood test, blood biochemistry index and control group compare, the difference not statistically significant.Made histopathological examination to examining internal organs, do not see specific lesions.
Show that through test it is safe taking ginseng peptide ammino acid beverage of the present invention.
Claims (3)
1. a seed ginseng peptide ammino acid beverage, it is characterized in that: described ginseng peptide ammino acid beverage is pressed column weight amount percentage range proportion raw material and is processed: TSPG extract 0.1～0.5%, corn oligopeptide 0.1～0.5%; Inositol 0.1～0.2%, lysine 0.15～0.2%, arginine 0.15～0.2%; Glycine 0.15～0.2%, taurine 0.05～0.15%, white granulated sugar 8～12%; Inspissated juice 2～10%, sodium carboxymethylcellulose 0.015～0.02%, citric acid 0.15～0.3%; Natrium citricum 0.1～0.2%, cycloheptaamylose 0.07～0.1%, flavoring essence 0.1～0.15%; All the other are pure water;
The method for distilling of above-mentioned TSPG extract is: get the ginseng pulverate and be broken into fine powder, be soaked in water, stir frequently, filter; Filtrating is through the macroporous absorbent resin post, and absorption finishes, and is washed with water to flow out the liquid clarification, washs with the water that contains alkaline inorganic washing agent again; To the eluate clarification, be washed with water to p H value again for 5-7, use ethanol elution instead, collect eluent; Concentrate, drying promptly gets the TSPG extract;
Above-mentioned ginseng peptide ammino acid method for preparing beverage is: with sterilized water white granulated sugar is dissolved, heats, and be incubated 10-15 minute down at 90-95 ℃, guarantee that syrup is aseptic; Squeeze into blend tank then; Sodium carboxymethylcellulose is squeezed into blend tank after milling treatment of colloid, squeeze into blend tank after TSPG extract and above-mentioned other raw material dissolvings and stir, and gets into the superhigh temperature flash pasteurizer through after the assay was approved; Sterilization between 125～130 ℃ after 10 seconds at 88～90 ℃ of following cans, cooling packings then;
Above-mentioned inspissated juice is any one or a few in cider or guava juice or peach juice or mango juice or the passion fruit juice; Above-mentioned essence is the essence corresponding with said fruit juice.
2. ginseng peptide ammino acid beverage according to claim 1 is characterized in that: described ginseng peptide ammino acid beverage is pressed column weight amount percentage range proportion raw material and is processed: TSPG extract 0.15%, corn oligopeptide 0.1%; Inositol 0.1%, lysine 0.2%, arginine 0.1%; Glycine 0.2%, taurine 0.1%, white granulated sugar 8%; Apple inspissated juice 20%, sodium carboxymethylcellulose 0.02%, citric acid 0.28%; Natrium citricum 0.15%, cycloheptaamylose 0.07%, flavoring apple essence 0.1%.All the other are pure water; Said essence is water apple flavor essence.
3. ginseng peptide ammino acid beverage according to claim 1 is characterized in that: described ginseng peptide ammino acid beverage presses that column weight amount percentage range proportion raw material processes: TSPG extract 0.2%, corn oligopeptide 0.2%; Inositol 0.2%, lysine 0.2%, arginine 0.1%; Glycine 0.2%, taurine 0.15%, white granulated sugar 10%; Honey peach fruit juice 20%, sodium carboxymethylcellulose 0.02%, citric acid 0.3%; Natrium citricum 0.2%, cycloheptaamylose 0.1%, honey peach essence 0.15%.All the other are pure water; Said essence is honey peach flavor essence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210024583 CN102524872B (en) | 2012-02-02 | 2012-02-02 | Ginseng peptide amino acid drink |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210024583 CN102524872B (en) | 2012-02-02 | 2012-02-02 | Ginseng peptide amino acid drink |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102524872A true CN102524872A (en) | 2012-07-04 |
| CN102524872B CN102524872B (en) | 2013-03-13 |
Family
ID=46333914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210024583 Active CN102524872B (en) | 2012-02-02 | 2012-02-02 | Ginseng peptide amino acid drink |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102524872B (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894444A (en) * | 2012-10-15 | 2013-01-30 | 康美药业股份有限公司 | Ginseng functional drink, preparation method of ginseng functional drink and application of ginseng functional drink |
| CN103230074A (en) * | 2013-05-09 | 2013-08-07 | 南京兴东峰生物科技有限公司 | Beverage taking rapeseed peptide as functional factors and preparation method thereof |
| CN103535801A (en) * | 2012-07-09 | 2014-01-29 | 钟虹光 | Health-care drink with physical fatigue relieving and anoxia endurance improving functions |
| CN104839820A (en) * | 2015-04-22 | 2015-08-19 | 钟兴欢 | Guava energy beverage |
| CN105105125A (en) * | 2015-09-09 | 2015-12-02 | 陈俊豪 | Pearl oyster amino acid liquid and pearl oyster and ginseng amino acid liquid production method |
| CN105146612A (en) * | 2015-07-28 | 2015-12-16 | 合肥维巧食品科技有限公司 | Functional beverage |
| CN105168257A (en) * | 2015-09-09 | 2015-12-23 | 陈贵卿 | Processing method of pearl liquid, pearl ginseng liquid and pearl powder easily absorbed by human body |
| CN106962704A (en) * | 2017-03-24 | 2017-07-21 | 张家富 | Amino acid beverage composition |
| CN107156819A (en) * | 2017-06-02 | 2017-09-15 | 宁夏全通枸杞供应链管理股份有限公司 | A kind of preparation and preparation method thereof of sobering up with anti-alcoholic liver injury effect |
| CN108094777A (en) * | 2018-01-10 | 2018-06-01 | 佛山推启农业研究院（普通合伙） | A kind of teenager's Chinese medicine composite beverage and preparation method thereof |
| CN118147260A (en) * | 2024-05-09 | 2024-06-07 | 上海惠盾因泰生物科技有限公司 | Co-extraction method of ginseng oligopeptide and rare saponin and application of extracted product |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101238886A (en) * | 2008-01-31 | 2008-08-13 | 王科大 | Salidroside fatigue-resistance beverage |
| CN102100805A (en) * | 2011-01-31 | 2011-06-22 | 上海东锦食品集团有限公司 | Composition for relieving physical fatigue and enhancing immunologic function, preparation method thereof and application thereof |
| CN102318866A (en) * | 2011-08-08 | 2012-01-18 | 桂林莱茵生物科技股份有限公司 | Beverage with effect of alleviating physical fatigue |
-
2012
- 2012-02-02 CN CN 201210024583 patent/CN102524872B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101238886A (en) * | 2008-01-31 | 2008-08-13 | 王科大 | Salidroside fatigue-resistance beverage |
| CN102100805A (en) * | 2011-01-31 | 2011-06-22 | 上海东锦食品集团有限公司 | Composition for relieving physical fatigue and enhancing immunologic function, preparation method thereof and application thereof |
| CN102318866A (en) * | 2011-08-08 | 2012-01-18 | 桂林莱茵生物科技股份有限公司 | Beverage with effect of alleviating physical fatigue |
Non-Patent Citations (1)
| Title |
|---|
| 李洪刚等: "树脂联用纯化人参总皂苷", 《中医药学刊》, vol. 23, no. 4, 30 April 2005 (2005-04-30) * |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103535801A (en) * | 2012-07-09 | 2014-01-29 | 钟虹光 | Health-care drink with physical fatigue relieving and anoxia endurance improving functions |
| CN103535801B (en) * | 2012-07-09 | 2016-04-20 | 钟虹光 | A kind of health drink that there is alleviating physical fatigue and improve anoxia endurance |
| CN102894444A (en) * | 2012-10-15 | 2013-01-30 | 康美药业股份有限公司 | Ginseng functional drink, preparation method of ginseng functional drink and application of ginseng functional drink |
| CN103230074A (en) * | 2013-05-09 | 2013-08-07 | 南京兴东峰生物科技有限公司 | Beverage taking rapeseed peptide as functional factors and preparation method thereof |
| CN104839820A (en) * | 2015-04-22 | 2015-08-19 | 钟兴欢 | Guava energy beverage |
| CN105146612A (en) * | 2015-07-28 | 2015-12-16 | 合肥维巧食品科技有限公司 | Functional beverage |
| CN105168257A (en) * | 2015-09-09 | 2015-12-23 | 陈贵卿 | Processing method of pearl liquid, pearl ginseng liquid and pearl powder easily absorbed by human body |
| CN105105125A (en) * | 2015-09-09 | 2015-12-02 | 陈俊豪 | Pearl oyster amino acid liquid and pearl oyster and ginseng amino acid liquid production method |
| CN106962704A (en) * | 2017-03-24 | 2017-07-21 | 张家富 | Amino acid beverage composition |
| CN107156819A (en) * | 2017-06-02 | 2017-09-15 | 宁夏全通枸杞供应链管理股份有限公司 | A kind of preparation and preparation method thereof of sobering up with anti-alcoholic liver injury effect |
| CN108094777A (en) * | 2018-01-10 | 2018-06-01 | 佛山推启农业研究院（普通合伙） | A kind of teenager's Chinese medicine composite beverage and preparation method thereof |
| CN118147260A (en) * | 2024-05-09 | 2024-06-07 | 上海惠盾因泰生物科技有限公司 | Co-extraction method of ginseng oligopeptide and rare saponin and application of extracted product |
| CN118147260B (en) * | 2024-05-09 | 2024-07-16 | 上海惠盾因泰生物科技有限公司 | Co-extraction method of ginseng oligopeptide and rare saponin and application of extracted product |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102524872B (en) | 2013-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102524872B (en) | Ginseng peptide amino acid drink | |
| CN102429235A (en) | Health care food with functions of relieving physical fatigue and enhancing immunity | |
| CN102526698A (en) | Cordyceps polypeptide amino acid nutrient solution | |
| CN107455625A (en) | A kind of nutrient for plants beverage and its preparation technology with antifatigue weight losing function | |
| CN101366521B (en) | Natural functional foods | |
| CN102630940B (en) | Cereal fiber paste powder used as nutritional breakfast | |
| CN1237910C (en) | Whole nutrient powder and its production method | |
| CN105661554A (en) | Silkworm chrysalis small molecule peptide chelate for improving immunity and preparation method thereof | |
| CN111374312A (en) | Health food for supplementing comprehensive nutrition and easy absorption | |
| CN105541967A (en) | Leech small peptide chelate with coagulation preventing and blood activating effect and preparation method thereof | |
| CN106418067B (en) | health beverage for supplementing physical strength and relieving fatigue | |
| CN102090637A (en) | Collagen-containing compound nutritious powder | |
| CN111467468A (en) | Concentrated nutrient solution containing ginseng, cordyceps militaris, ginger and wolfberry fruit and preparation method thereof | |
| CN107439866A (en) | Matrimony vine chickpea plant nutrients beverage and its preparation technology | |
| CN115590069A (en) | Composition containing pea peptide and preparation method and application thereof | |
| CN109998004A (en) | A kind of formula and preparation method thereof of birch young pilose antler small-molecular peptides solid beverage | |
| CN113229431A (en) | White-meat lucid ganoderma sports beverage and preparation method thereof | |
| CN102948733B (en) | Production method and formula of special-eating life nutrition liquid | |
| CN102511882A (en) | Red jujube thick syrup beneficial for improving growth and development | |
| CN105831735A (en) | Quinoa infant super nutrient powder | |
| CN106309551A (en) | Perilla seed compound preparation and preparation method thereof | |
| CN110522028A (en) | A kind of composition that protect liver is antifatigue and its application | |
| CN108652010B (en) | Omega 3 quick solvent and preparation method thereof | |
| CN106070794A (en) | One purifies the blood health protection tea and preparation method thereof | |
| CN106063503A (en) | Metallothionein rich selenium germanium yoghurt product technique |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Ginseng peptide amino acid drink Effective date of registration: 20150423 Granted publication date: 20130313 Pledgee: Bank of Quanzhou, Limited by Share Ltd, Zhangzhou, Longwen branch Pledgor: Fujian Kangzhiwei Food Industry Co., Ltd. Registration number: 2015350000025 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20180907 Granted publication date: 20130313 Pledgee: Bank of Quanzhou, Limited by Share Ltd, Zhangzhou, Longwen branch Pledgor: Fujian Kangzhiwei Food Industry Co., Ltd. Registration number: 2015350000025 |