CN102512649A - Composition of Chinese medicinal herbs for treating postpartum blood stasis and preparation method thereof - Google Patents

Composition of Chinese medicinal herbs for treating postpartum blood stasis and preparation method thereof Download PDF

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CN102512649A
CN102512649A CN2011104483549A CN201110448354A CN102512649A CN 102512649 A CN102512649 A CN 102512649A CN 2011104483549 A CN2011104483549 A CN 2011104483549A CN 201110448354 A CN201110448354 A CN 201110448354A CN 102512649 A CN102512649 A CN 102512649A
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石圣洪
赵良彬
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Abstract

The invention relates to the field of Chinese medicinal herbs and particularly relates to a composition of Chinese medicinal herbs for treating a postpartum blood stasis, and a preparation method thereof. The composition of the Chinese medicinal herbs for treating the postpartum blood stasis is prepared from the following raw materials in parts by weight: 850-900 parts of angelica sinensis, 250-350 parts of ligusticum wallichii, 80-100 parts of peach kernel, 40-60 parts of radix glycyrrhizae preparate, 55-75 parts of ginger carbo, 1100-1200 parts of leonurus and 40-60 parts of safflower. The composition of the Chinese medicinal herbs disclosed by the invention has the functions of activating blood, dissolving stasis, dredging collaterals and relieving pain, can be prepared to be a sucrose-free preparation with a dosage of 7 g per time, and can be used for obviously improving the symptoms of postpartum blood stasis and lochiorrhea. The composition of the Chinese medicinal herbs is conveniently used for treating the postpartum blood stasis, has obvious curative effects, no toxicity and side effects and good taking compliance of a patient due to not containing matters difficult to dissolve, such as brown sugar and the like. The composition of the Chinese medicinal herbs is suitable for the diabetic patients and the patients who not are fond of eating sugar, can be widely applied to clinical treatment of the postpartum blood stasis, and has a wide market prospect.

Description

A kind of Chinese medicine composition of treating postnatal blood stasis and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, relate to a kind of Chinese medicine composition of treating postnatal blood stasis and preparation method thereof specifically.
Background technology
Postnatal blood stasis is meant disease such as vaginal hemorrhage behind metrorrhagia in puerperal, uterus meromorphosis, prolonged lochia, the artificial abortion, and sickness rate is very high.The traditional Chinese medical science thinks that postnatal blood stasis one disease is many by the vessels of the whole body being deficient in puerperal, and daily life makes the cold-evil take advantage of the empty uterus vessels of the uterus of invading accidentally, and blood is cold coagulation, blood-stasis internal-depression; Or feelings will is unsuccessful, and the liver catharsis of wetting is strongly fragrant and do not reach qi depression to blood stasis; Or afterbirth is residual, fill the post of not smooth, blood-stasis internal-depression, escape of blood from meridian forms.
The treatment postnatal blood stasis adopts tcm therapy more at present, contains brown sugar in the prescriptions of Chinese medicine more.Brown sugar is warm in nature, sweet in the mouth, go into spleen, have QI replenishing and blood tonifying, spleen invigorating warming the stomach, slow in the effect of pain relieving, activating blood circulation to dissipate blood stasis.The traditional Chinese medical science thinks that women's health in puerperal becomes silted up more, and eight arteries and veins are hollow, whenever cause stomachache.Food brown sugar can lead to silt, row's lochia, thereby reaches aim of alleviating pain.Yet brown sugar belongs to raw sugar, and more impurity is contained in the inside, is difficult to when taking after mixing it with water melt, and it is relatively poor to cause the patient to take compliance.And the raw material of brown sugar is a Caulis Sacchari sinensis, contains the sucrose about 95%, the diabetics inedibility.
Summary of the invention
In view of this, the object of the invention provides a kind of Chinese medicine composition of treatment postnatal blood stasis evident in efficacy, that do not contain brown sugar.
For realizing the object of the invention, the present invention adopts following technical scheme:
A kind of Chinese medicine composition of treating postnatal blood stasis, process by following weight portion raw material:
80~100 parts in 250~350 parts of Semen Persicaes of 850~900 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1100~1200 parts of 55~75 parts of Herba Leonuris of 40~60 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
40~60 parts on Flos Carthami.
Chinese medicine composition according to the invention is selected seven flavor Chinese crude drugs such as Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Persicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens charcoal, Herba Leonuri and Flos Carthami for use.
Wherein, Radix Angelicae Sinensis, latin name Angelica sinensis has another name called Radix Angelicae Sinensis, cloud is returned, and is the dry root of umbelliferae angelica.The Radix Angelicae Sinensis root is slightly cylindrical, and " returning head " claimed in the root upper end, and main root is claimed " returning body " or " very little body ".Supporting root is claimed " Radix Angelicae Sinensis " or " returning lower limb ", all claim " QUANGUI ".Radix Angelicae Sinensis is enriched blood and is invigorated blood circulation, and the Radix Angelicae Sinensis body is enriched blood, and Radix Angelicae Sinensis is invigorated blood circulation.Radix Angelicae Sinensis is warm in nature; Sweet in the mouth, suffering; Having enriches blood invigorates blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation, is mainly used in diseases such as treatment blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Rhizoma Chuanxiong, latin name Rhizoma Chuanxiong, the another name Rhizoma Chuanxiong is samphire Rhizoma Chuanxiong rhizome.The Rhizoma Chuanxiong acrid in the mouth, warm in nature, have blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; The effect of wind-expelling pain-stopping is used for pain in chest and hypochondrium, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, fall and pounce on the pain of injury, menoxenia, the amenorrhea dysmenorrhea, puerperal disease such as stasis of blood pain.
(semenpersicae, peachseed), another name Radix Fici Hirtae core, almond core, big Semen Persicae are the seed of Folium rosae multiflorae plant peach (prunuspersicabatsch) to Semen Persicae.Sweet flat, the bitter in the mouth of Semen Persicae property has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, diseases such as dryness of the intestine constipation.
Radix Glycyrrhizae; Another name Herba Hedyotis cantonensis root, Radix Glycyrrhizae, Radix Glycyrrhizae are dicotyledon pulse family Radix Glycyrrhizae (Glycyrrhiza uralensis Fisch.); The root and rhizome of Glycyrrhiza inflata Bat. (G.inflata Bat.) or Glycyrrhiza glabra L. (G.glabra L.); Be a kind of tonification Chinese herbal medicine, detoxifcation is arranged, eliminate the phlegm, pain relieving, spasmolytic be so that pharmacological action such as anticancer.On the traditional Chinese medical science, the Radix Glycyrrhizae invigorating the spleen and replenishing QI is grown and to be coughed lung moistening, and the emergency detoxifcation is in harmonious proportion hundred medicines.The clinical practice branch " is given birth to and uses " with " processed with honey " not." give birth to " Radix Glycyrrhizae has another name called Radix Glycyrrhizae, SHENGCAO, and Radix Glycyrrhizae is for crude drug is removed impurity, cleaned, runs through the section life with being used as medicine; " processed with honey " has another name called Radix Glycyrrhizae Preparata, Radix Glycyrrhizae Preparata, Radix Glycyrrhizae, Radix Glycyrrhizae (processed with honey), and the Radix Glycyrrhizae tabellae of making a living is mixed thoroughly with Mel, fries to tack-free taking-up airing again, is used as medicine then.Radix Glycyrrhizae Preparata according to the invention is " processed with honey " Radix Glycyrrhizae, and promptly the honey of Radix Glycyrrhizae is smoked processed goods, and property is flat, and sweet in the mouth has the effect of spleen reinforcing stomach function regulating, Yiqi and vein recovery, is used for weakness of the spleen and stomach, fatigue and weakness, severe palpitation, diseases such as irregularly intermittent and regularly intermittent pulse.
Rhizoma Zingiberis Recens carbon is the big gun article that the dry rhizome of zingiber (Zingiber offcinale Rose.) forms through parch to black, and is warm in nature, and bitter in the mouth, suffering, puckery have warming the meridian for stopping bleeding, warming spleen and stopping diarrha effect, diseases such as curing mainly the haematemesis of deficiency and coldness property, have blood in stool, metrorrhagia, yang deficiency are had loose bowels.
Herba Leonuri is the young stem and leaf of labiate Herba Leonuri (Leonurus heterophyllus Sweet.).The Herba Leonuri young stem and leaf contains multiple nutritional components such as protein, carbohydrate.Herba Leonuri is cool in nature, acrid in the mouth is bitter; Have invigorate blood circulation, the effect of blood stasis dispelling, regulating menstruation, the water that disappears, cure mainly water, hematuria under menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, carbuncle skin infection, the edema, rush down blood, dysentery, haemorrhoids.
Flos Carthami is claimed Flos Carthami again, is the tubular corolla of feverfew Flos Carthami (Carthamus tinctorius L.); The special fragrance of tool; Warm in nature, acrid in the mouth has the effect of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; It is not all right to cure mainly stagnate stomachache, lochia of dysmenorrhea, amenorrhea, puerperal blood faints, the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, macular eruption being dark-purple.
As preferred said Chinese medicine composition, process by following weight portion raw material:
90 parts in 300 parts of Semen Persicaes of 890 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1150 parts of 60 parts of Herba Leonuris of 50 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
55 parts on Flos Carthami.
The present invention also provides the clinical preparation of said Chinese medicine composition.It is required various pharmaceutically conventional adjuvants that those skilled in the art can add the preparation different dosage form with Chinese medicine composition according to the invention according to requirement of different patients; Like disintegrating agent, lubricant, emulsifying agent, binding agent etc.; With conventional method of Chinese medicinal, process gynecological's common dosage forms such as tablet, capsule, oral liquid, pill, granule, powder, drop pill, spray etc. through the direct or indirect adding acceptable auxiliary pharmaceutically of conventional processing.
Preferably, the clinical preparation of Chinese medicine composition according to the invention is granule, tablet and pill, is prone to take, and curative effect is obvious.
Preferably, each preparation unit of clinical preparation of Chinese medicine composition according to the invention is 5~8g, more preferably 7g.
The present invention also provides the method for preparing of said Chinese medicine composition.
A kind of method for preparing of treating the Chinese medicine composition of postnatal blood stasis comprises:
Step 1: get 850~900 weight portion Radix Angelicae Sinensis, 250~350 weight portion Rhizoma Chuanxiongs, 80~100 weight portion Semen Persicaes, 40~60 weight portion Radix Glycyrrhizae Preparatas, 55~75 weight portion Rhizoma Zingiberis Recens charcoals, 1100~1200 weight portion Herba Leonuris and 40~60 weight portion Flos Carthamis; Be ground into coarse powder extracting in water volatile oil, collect volatile oil and distillation obtained aqueous solution respectively;
Step 2: with the decocte with water of gained medicinal residues, filter, filtrating merges with step 1 obtained aqueous solution, is condensed into relative density 1.05~1.10 extractum, and drying sprays into step 1 gained volatile oil, promptly gets.
As preferably, method for preparing according to the invention, the said extracting in water volatile oil of step 1 is for adding 10 times of weight water distillation and extraction 4 hours.
Preferably, the decocte with water of the said gained medicinal residues of step 2 is the decocte with water secondary, adds the water of 12 times of weight for the first time, decocts 2 hours, adds the water of 10 times of weight for the second time, decocts collecting decoction 1.5 hours.
The present invention also provides the Chinese medicine composition of above-mentioned method for preparing preparation.
The invention provides a kind of granule of treating postnatal blood stasis for after being concentrated into relative density at above-mentioned said Chinese medicine composition and being 1.05~1.10 extract dries; Add 600~700 weight portion dextrin and 5~15 weight portion steviosin mixings; Process granule with ethanol; Drying sprays into volatile oil again, promptly gets.
The present invention in 120 routine postnatal blood stasis patients, after 15 days, cures 116 examples with traditional Chinese medicine composition for treating according to the invention through clinical observation on the therapeutic effect; Cure rate accounts for 96.7%, 3 examples that take a turn for the better, and obvious effective rate accounts for 2.5%; Total effective rate is 99.2%, invalid 1 example, and inefficiency accounts for 0.8%.Compare raising evident in efficacy with contrast.
The invention provides a kind of Chinese medicine composition of treatment postnatal blood stasis of determined curative effect, modern pharmacology research and clinical trial show that Chinese medicine composition according to the invention has the effect of blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain; Can obviously improve the symptom of postnatal blood stasis, lochiorrhea, the treatment postnatal blood stasis is easy to use, evident in efficacy; Have no side effect, comfortable safety does not contain simultaneously brown sugar etc. and is difficult to melt thing; It is good that the patient takes compliance, is fit to diabetics and do not like the sugar edible for patients, is prevention and the good medicine of treating postnatal blood stasis; Can be widely used in the clinical treatment of postnatal blood stasis, have vast market prospect.
The specific embodiment
The embodiment of the invention discloses a kind of Chinese medicine composition of treating postnatal blood stasis and preparation method thereof.Those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are regarded as and are included in the present invention.Product of the present invention and method are described through preferred embodiment; The related personnel obviously can be in not breaking away from content of the present invention, spirit and scope to product as herein described with method is changed or suitably change and combination, realize and use technology of the present invention.
In order further to understand the present invention, the present invention is elaborated below in conjunction with embodiment.
Embodiment 1: the Chinese medicine composition of treatment postnatal blood stasis according to the invention
Said Chinese medicine composition is to be processed by following bulk drugs:
80 parts in 350 parts of Semen Persicaes of 850 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1200 parts of 55 parts of Herba Leonuris of 60 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
40 parts on Flos Carthami.
Method for preparing is to get the Radix Angelicae Sinensis of said weight, Rhizoma Chuanxiong, Semen Persicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens charcoal, Herba Leonuri and Flos Carthami to be ground into the water extraction volatile oil 4 hours that coarse powder adds 10 times of weight, collects volatile oil and distillation obtained aqueous solution respectively; With gained medicinal residues decocte with water secondary, add the water of 12 times of weight for the first time, decocted 2 hours, add the water of 10 times of weight of water for the second time; Decocted 1.5 hours, collecting decoction filters, and filtrating merges with obtained aqueous solution; Be condensed into relative density 1.05~1.10 extractum, drying sprays into gained volatile oil, promptly gets.
Embodiment 2: the Chinese medicine composition of treatment postnatal blood stasis according to the invention
Said Chinese medicine composition is to be processed by following bulk drugs:
100 parts in 250 parts of Semen Persicaes of 900 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1100 parts of 75 parts of Herba Leonuris of 40 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
60 parts on Flos Carthami.
Method for preparing is to get the Radix Angelicae Sinensis of said weight, Rhizoma Chuanxiong, Semen Persicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens charcoal, Herba Leonuri and Flos Carthami to be ground into the water extraction volatile oil 4 hours that coarse powder adds 10 times of weight, collects volatile oil and distillation obtained aqueous solution respectively; With the decocte with water of gained medicinal residues, filter, filtrating merges with obtained aqueous solution, is condensed into relative density 1.05~1.10 extractum, and drying sprays into gained volatile oil, promptly gets.
Embodiment 3: the Chinese medicine composition of treatment postnatal blood stasis according to the invention
Said Chinese medicine composition is to be processed by following bulk drugs:
90 parts in 300 parts of Semen Persicaes of 890 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1150 parts of 60 parts of Herba Leonuris of 50 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
55 parts on Flos Carthami.
Method for preparing is to get the Radix Angelicae Sinensis of said weight, Rhizoma Chuanxiong, Semen Persicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens charcoal, Herba Leonuri and Flos Carthami to be ground into the water extraction volatile oil 4 hours that coarse powder adds 10 times of weight, collects volatile oil and distillation obtained aqueous solution respectively; With gained medicinal residues decocte with water secondary, add the water of 12 times of weight for the first time, decocted 2 hours, add the water of 10 times of weight of water for the second time; Decocted 1.5 hours, collecting decoction filters, and filtrating merges with obtained aqueous solution; Be condensed into relative density 1.05~1.10 extractum, drying sprays into gained volatile oil, promptly gets.
Embodiment 4: the observation of curative effect of Chinese medicine composition according to the invention
Observe the curative effect of using traditional Chinese medicine composition for treating postnatal blood stasis according to the invention.
240 routine postnatal blood stasis patients are divided into experimental group and matched group at random; Experimental group 120 examples, matched group 120 examples are taken the Chinese medicine composition of embodiment 3 preparations and traditional decoction SHENGHUATANG respectively and are treated; One day twice; Took continuously 15 days, and observed clinical efficacy, stop other western medicines in treatment during the treatment.
Observation of curative effect: the present invention has obtained curative effect preferably clinically, in 120 routine postnatal blood stasis patients, with traditional Chinese medicine composition for treating according to the invention after 15 days; Cure 116 examples, cure rate accounts for 96.7%, and 3 examples take a turn for the better; Obvious effective rate accounts for 2.5%; Total effective rate is 99.2%, invalid 1 example, and inefficiency accounts for 0.8%.The Chinese medicine composition group of embodiment 1 and embodiment 2 preparations is similar with the Chinese medicine composition group clinical efficacy of embodiment 3 preparations, no difference of science of statistics.The matched group cure rate is that 74.3%, two group of cure rate relatively has significant difference (P<0.05).
Embodiment 5: the granule of treatment postnatal blood stasis according to the invention
Prescription is formed (by 1000 bags of calculating)
Figure BDA0000126167170000061
Method for preparing is to get the Radix Angelicae Sinensis of said weight, Rhizoma Chuanxiong, Semen Persicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens charcoal, Herba Leonuri and Flos Carthami to be ground into the water extraction volatile oil 4 hours that coarse powder adds 10 times of weight, collects volatile oil and distillation obtained aqueous solution respectively; With gained medicinal residues decocte with water secondary, add the water of 12 times of weight for the first time, decocted 2 hours, add the water of 10 times of weight of water for the second time; Decocted 1.5 hours, collecting decoction filters; Filtrating merges with obtained aqueous solution, is condensed into relative density 1.05~1.10 extractum, gets extractum 345g.Add 645g dextrin and 10g steviosin mixing, 85% ethanol soaks into, and adds then in the efficient wet granulator, and stirring, high-speed cutting 2min process granule rapidly.50 ± 5 ℃ of drying 15~20min of EAT spray into gained volatile oil, sieve granulate with 1.5mm, promptly get.Each preparation unit is that every bag of specification is 7g.
Embodiment 6: embodiment 5: the granule of treatment postnatal blood stasis according to the invention
Prescription is formed (by 1000 bags of calculating)
Figure BDA0000126167170000071
Method for preparing is to get the Radix Angelicae Sinensis of said weight, Rhizoma Chuanxiong, Semen Persicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens charcoal, Herba Leonuri and Flos Carthami to be ground into the water extraction volatile oil 4 hours that coarse powder adds 10 times of weight, collects volatile oil and distillation obtained aqueous solution respectively; With gained medicinal residues decocte with water secondary, add the water of 12 times of weight for the first time, decocted 2 hours, add the water of 10 times of weight of water for the second time; Decocted 1.5 hours, collecting decoction filters; Filtrating merges with obtained aqueous solution, is condensed into relative density 1.05~1.10 extractum, gets extractum 315g.Add 680g dextrin and 5g steviosin mixing, 85% ethanol soaks into, and adds then in the efficient wet granulator, and 6 speed stir, high-speed cutting 2min, process granule.50 ± 5 ℃ of drying 15~20min of EAT spray into gained volatile oil, sieve granulate with 1.5mm, promptly get.Each preparation unit is that every bag of specification is 7g.
Further provide two examples more detailed concrete case below:
Case 1, woman, 30 years old, puerperal lower abdomen pain, colporrhagia is not to the utmost dripping, continues 2 months.
Take the Chinese medicine composition of the embodiment of the invention 3 preparations, serve on 7 days, the lower abdomen pain weakens.Continue to take 7 days, abdominal pain disappears, and ill symptoms disappears.
Case 2, woman, 25 years old, the frequent pain of lower abdomen in puerperal, when serious pain unbearably, menstruation is undesired all the time, vagina is regular hemorrhage, and with bad smell, continues 3 months, takes multiple medicine and does not all take effect.
Take the granule 15 days of the treatment postnatal blood stasis of the embodiment of the invention 5 preparation, above-mentioned symptom disappears.
The explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof.Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of claim of the present invention.

Claims (10)

1. Chinese medicine composition of treating postnatal blood stasis, process by following weight portion raw material:
80~100 parts in 250~350 parts of Semen Persicaes of 850~900 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1100~1200 parts of 55~75 parts of Herba Leonuris of 40~60 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
40~60 parts on Flos Carthami.
2. Chinese medicine composition according to claim 1 is characterized in that, is processed by following weight portion raw material:
90 parts in 300 parts of Semen Persicaes of 890 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1150 parts of 60 parts of Herba Leonuris of 50 portions of Rhizoma Zingiberis Recens of Radix Glycyrrhizae Preparata charcoal
55 parts on Flos Carthami.
3. comprise the clinical preparation of claim 1 or 2 described Chinese medicine compositions, it is characterized in that, process by the Chinese medicine composition of said treatment diabetes and pharmaceutically conventional adjuvant combination.
4. according to the said clinical preparation of claim 3, it is characterized in that it is oral liquid, granule, tablet, pill, powder or capsule.
5. according to the said clinical preparation of claim 3, it is characterized in that each preparation unit is 5~8g.
6. the method for preparing of the Chinese medicine composition of a treatment postnatal blood stasis is characterized in that, comprising:
Step 1: get 850~900 weight portion Radix Angelicae Sinensis, 250~350 weight portion Rhizoma Chuanxiongs, 80~100 weight portion Semen Persicaes, 40~60 weight portion Radix Glycyrrhizae Preparatas, 55~75 weight portion Rhizoma Zingiberis Recens charcoals, 1100~1200 weight portion Herba Leonuris and 40~60 weight portion Flos Carthamis; Be ground into coarse powder extracting in water volatile oil, collect volatile oil and distillation obtained aqueous solution respectively;
Step 2: with the decocte with water of gained medicinal residues, filter, filtrating merges with step 1 obtained aqueous solution, is condensed into relative density 1.05~1.10 extractum, and drying sprays into step 1 gained volatile oil, promptly gets.
7. according to the said method for preparing of claim 6, it is characterized in that the said extracting in water volatile oil of step 1 is for adding 10 times of weight water distillation and extraction 4 hours.
8. according to the said method for preparing of claim 6, it is characterized in that the decocte with water of the said gained medicinal residues of step 2 is the decocte with water secondary, add the water of 12 times of weight for the first time, decocted 2 hours, add the water of 10 times of weight of water for the second time, decocted collecting decoction 1.5 hours.
9. the Chinese medicine composition of the said method for preparing of claim 6~8 preparation.
One kind the treatment postnatal blood stasis granule; It is characterized in that, after the said Chinese medicine composition of claim 9 is concentrated into relative density and is 1.05~1.10 extract dries, add 600~700 weight portion dextrin and 5~15 weight portion steviosin mixings; Process granule with ethanol; Drying sprays into volatile oil again, promptly gets.
CN2011104483549A 2011-12-28 2011-12-28 Composition of Chinese medicinal herbs for treating postpartum blood stasis and preparation method thereof Pending CN102512649A (en)

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汪国华等: "生化颗粒剂提取工艺的优化", 《中药材》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109550036A (en) * 2019-01-15 2019-04-02 遵义医学院附属医院 For puerperal clot-dispersing pain-relieving medicinal composition
CN112316092A (en) * 2020-10-26 2021-02-05 酒钢医院 Medicine for treating postpartum blood deficiency and congealing cold and blood stasis obstruction and preparation thereof
CN116920067A (en) * 2022-03-30 2023-10-24 湖南安邦制药股份有限公司 Preparation method of new biochemical particles
CN115006501A (en) * 2022-07-14 2022-09-06 海南医学院 Composition for post-drug-induced abortion conditioning and application thereof

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Application publication date: 20120627