CN102512591B - Composition with functions of losing weight and reducing blood glucose and lipid - Google Patents
Composition with functions of losing weight and reducing blood glucose and lipid Download PDFInfo
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- CN102512591B CN102512591B CN201110421555.XA CN201110421555A CN102512591B CN 102512591 B CN102512591 B CN 102512591B CN 201110421555 A CN201110421555 A CN 201110421555A CN 102512591 B CN102512591 B CN 102512591B
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Abstract
The invention relates to the field of Chinese medicinal health-care product compositions, in particular to a composition with the functions of losing weight, reducing blood glucose and lipid, which is used for overcoming defects existing in the conventional product with the functions of losing weight and reducing blood glucose and lipid. The composition is prepared from the following raw materials in parts by weight: 1-10 parts of boneset leaf and flower in any ratio, 1-10 parts of polygonatum, 1-10 parts of Chinese yam, 1-10 parts of grifola, 1-10 parts of folium mori and 1-10 parts of radices trichosanthis. The invention provides the composition with the functions of losing weight and reducing blood glucose and lipid specific to the defects existing in the conventional product with the functions of losing weight and reducing blood glucose and lipid. The composition is selected from natural plants, has low cost, a remarkable curative effect, and the characteristics of stability and capability of long-term taking, does not influence normal food intake of a human body, and is particularly suitable for people suffering from deficiency of both qi and yin as well as qi stagnation and blood stasis; and the defects of poor curative effect, strong toxic and side effects and easiness in reoccurring after medicament quitting existing in the conventional product with the functions of losing weight and reducing blood glucose and lipid are overcome.
Description
Technical field
The present invention relates to the Chinese medicine health care product compositions field, specifically a kind of compositions with effects of losing weight and lowering blood sugar and blood lipid.
Background technology
Obesity, hyperlipidemia, diabetes have become the most serious public health problem of developed country and developing country's facing at present, mid-aged population embody especially obvious.
At present, the treatment for obesity adopt dietetic treatment more, exercise therapy, pharmacotherapy.Dietetic therapy is a kind ofly to carry out the method for body weight control by the total intake that suppresses energy, even successfully fat-reducing also can bring the body constitution problems such as malnutrition, hunger sensation take place frequently to the patient, is a kind of method that can not life-time service.When adopting exercise therapy, need to continue violent oxygen consumption motion, adhere to relatively difficulty.Pharmacotherapy, most slimming medicine can to health generation toxic and side effects in various degree, be not suitable for long-term taking after taking.
Treatment for hyperlipidemia, diabetes, because the employing chemicals can produce toxic and side effects in various degree, easily recurrence after the drug withdrawal, therefore, do not re-used the method for simple chemicals for the treatment conditioning of hyperlipidemia, diabetes, a large amount of health product that play a role by natural plants are developed out, but these health product are only paid attention to certain single class patient mostly, and in fact the infirmities of age such as diabetes, hyperlipidemia all can occur with it a patient usually.
Summary of the invention
The present invention is directed to the defective that existing product with fat-reducing, blood sugar lowering, effect for reducing blood fat exists, a kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is provided.
The present invention is achieved by the following technical solutions: a kind of compositions with effects of losing weight and lowering blood sugar and blood lipid, made by the raw material of following parts by weight, with Herba Chlorophyti leaf and flower 1-10 part of any proportioning, Rhizoma Polygonati Odorati 1-10 part, Rhizoma Dioscoreae 1-10 part, Polyporus 1-10 part, Folium Mori 1-10 part, Radix Trichosanthis 1-10 part.
Further, 10 parts of described Rhizoma Polygonati Odorati, 10 parts of Rhizoma Dioscoreaes, 10 parts of Polyporus, 10 parts on Folium Mori, 10 parts of Radix Trichosanthis.
Compositions with effects of losing weight and lowering blood sugar and blood lipid of the present invention, according to the health product processing criterion, it is for oral administration to make various dosage forms, and described compositions is tablet, colloid, oral agents, drink agent.
The present invention is based on traditional medical theory, protect the natural plants that filters out the storehouse from motherland's medical science, medicine, make by the theory of Chinese medical science prescription, effect of the present invention and indication: have clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, replenishing QI to invigorate the spleen, the effect of dampness removing toxin expelling, especially take Herba Chlorophyti as monarch drug, " five tastes entrance is hidden in stomach; spleen is the trip vital essence; body fluid is at spleen, so make us sweet taste in the mouth also, this fertile sending out also; this person must count the sweet and refreshing and many fertilizer of food also; overeating greasy food bringing about internal heat, over-eating the food with sweet flavor bringing about abdominal distension, its gas overflow; transfer to and quenching one's thirst according to " interior through Plain Questions " record, treating with Herba EuPatorii, removing the accumulation of stale pathogen are also ".
Herba Chlorophyti: the traditional Chinese medical science is discussed, and by " Plain Questions " cloud, five tastes entrance is hidden in taste; With its vital essence of row, body fluid makes us sweet taste in the mouth at spleen, this fertile sending out also, and its gas overflow transfers to and quenching one's thirst, and treating with Herba EuPatorii, removing the accumulation of stale pathogen are also.Wang Bing annotates cloud, so suffering can be dispersed also, Li Dongyuan controls that quenching one's thirst promotes the production of body fluid and drink Lan Ye, lid this in this.Herba Chlorophyti, Herba Lycopi, the fragrant and temperature of gas, acrid in the mouth and fall apart, the yang aspect of yin, lunar, JUE YIN meridian medicine is also enough.Spleen happiness fragrance, liver should be hot loose, temper is relaxed, then three warmers tonneau and healthy energy and; Stagnation of liver-QI is loose, and then battalion defends popular and the pathogenic factor solution.Herba Chlorophyti walks air flue, so the energy dredging water passages, except accumulation of phlegm in the hypochondrium, legendary venomous insect is warded off evil extremely, and for quenching one's thirst good medicine; Modern medicine study, Herba Chlorophyti contain Fatty acid component 14-methyl pentadecanoic acid, linoleic acid plus linolenic acid, is the nutritional labeling of human body necessity, and linoleic acid can promote the discharge of cholesterol and bile, reduces blood middle cholesterol content; Linoleic acid has important function in the information transmission of brain, it can make the brain cell activation, stops cerebral thrombosis, and human body blood lipid metabolism is also had important function, therefore can play the diseases such as prevention cerebral thrombosis and cerebral hemorrhage.Linolenic acid is to keep the life core substance that human brain is evolved.Have treatment cardiovascular system diseases, blood fat reducing, hypotensive action and antiplatelet aggregation inhibitory action, suppress thromboxane A
2Anabolic effect.Modern medicine study shows that Herba Chlorophyti has blood fat reducing, blood sugar lowering, effect of weight reducing.
Rhizoma Polygonati Odorati: the traditional Chinese medical science thinks that Rhizoma Polygonati Odorati has that dry throat and mouth, the interior-heat of the cloudy liquid consumption of nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, cough caused by dryness, chronic cough, calentura wounds are quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, giddy are dizzy, the effect of muscle arteries and veins spasm and pain.Modern medicine study: polygonati rhizoma contains convallamarin, convallarin, nimbecetin glycoside, d-quercitol glycoside, Saponin, 4-oxo-1,4-pyran-2,6-dicarboxylic acid, lymphatic temperament, asparagine, glucose, arabinose and mannitol, and still starch-containing 25.6%～30.6% and vitamin A, vitamin C.Contain Rhizoma Polygonati Odorati glycoside, carotene, vitamin C in the leaf and contain C
25-C
32Aldehyde material.Experimental study shows: Rhizoma Polygonati Odorati has blood pressure lowering, blood sugar lowering, blood fat reducing, and myocardial ischemia is had certain protective effect.
Rhizoma Dioscoreae: Rhizoma Dioscoreae sweet in the mouth, property are flat, enter lung, spleen, kidney channel, and be not dry oiliness, has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, helps the five internal organs, bone and muscle strengthening, grows that will is calmed the nerves, the effect of life lengthening.Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity are weak, the red disease such as swollen, fat of the frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.Modern medicine proves that Rhizoma Dioscoreae contains a large amount of mucus albumen, electrolytes and minerals, can effectively stop blood fat in the precipitation of blood vessel wall, and prevention painstaking effort disease obtains the mind calming and mentality promoting, blood sugar lowering, the effect of life lengthening.
Polyporus: Polyporus sweet in the mouth, light, flat, return kidney, urinary bladder channel, promoting diuresis to eliminate damp pathogen is controlled dysuria, edema, is had loose bowels, stranguria with turbid discharge, leukorrhagia.Shennong's Herbal record: Polyporus " clothes are made light of one's life by commiting suicide anti-old for a long time "." so blood is prosperous anti-old for Polyporus sweet in the mouth strengthening the spleen, the spleen governs the blood in the Ye Tianshi great master of Qing Dynasty discussion.Hot sweet lung benefiting, lung governing qi, gas and event body are gently also ".Modern medicine study shows, Polyporus contains crude protein 7.89%, ether-soluble extractives 0.24%, crude fibre 46.06%, soluble sugar and grades; Also containing free and conjunction type biotin, 2-hydroxyl-lignoceric acid, ergosterol, the effect that have diuretic antihypertensive, antitumor, adjusting immunologic function, protects the liver.
Folium Mori: the traditional Chinese medical science is thought, the Folium Mori sweet in the mouth, and hardship, cold in nature, return lung, Liver Channel.Effect: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving, cooling blood for hemostasis.It is dry to be used for dizziness, blurring of vision, lung-heat type cough, sweet cold tonifying YIN, cool lung moistening that anemopyretic cold and conjunctival congestion and swelling pain, wind-fire order disease (such as acute conjunctivitis), deficiecny of liver-YIN, excessive rising of liver-YANG cause, so can be used for dryness-heat impairing the lung, the few expectorant of dry cough.Compendium of Material Medica record, Folium Mori are hands, the bright medicine of foot sun, control the consumptive fever cough, and the long hair that makes eye bright is only quenched one's thirst.Modern medicine study: Folium Mori contain the compositions such as inokosterone, ecdysterone, β-Bao sterol, globulariacitrin, Mulberry glycoside, scopolin, choline, adenine, aminoacid, Fumaric acid, folic acid and vitamin C, carotene, meso inositol, polyisoprene alcohols material, have the effects such as blood sugar lowering, antihypertensive diuretic, spasmolytic, antiinflammatory.
Radix Trichosanthis: the traditional Chinese medical science thinks, sweet, the little hardship of Radix Trichosanthis nature and flavor, is slightly cold, and attaches to the lung and stomach meridians.Effect: clearing away heat and promoting production of body fluid, detumescence and apocenosis.Cure mainly: be used for the calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.Modern medicine study, Radix Trichosanthis contains protein alpha-Momorcharin and β-Momorcharin has induced labor, immunosuppressant and antitumor action, still isolates protein alpha-Trichosanthin, the cytotoxic protein Trichosanthin-ZG that is comprised of 289 aminoacid and the polypeptide with trypsin inhibition activity etc.Containing saccharide compound in the radices trichosanthis is THFPS, and obvious immunoregulation effect is arranged, and can strengthen immunocompetence, has significant antitumor and cytotoxic activity.Polysaccharide mainly is comprised of glucose, galactose, fructose, mannose, xylose and a small amount of protein. from the radices trichosanthis water extract, isolate 5 radices trichosanthis polysaccharide (Trichosan) A, B, C, D, E with hypoglycemic activity.Contain in addition several amino acids, have the effects such as blood sugar lowering, antitumor, adjusting immunologic function.
Compositions with effects of losing weight and lowering blood sugar and blood lipid of the present invention, be selected from natural plants, cost is lower, overcome that the product curative effect that has at present fat-reducing, blood sugar lowering, effect for reducing blood fat is bad, toxic and side effects is large, withdraw the defective of rear easy recurrence, but have the stably characteristics of long-term taking, and do not affect the food intake of human normal, be particularly useful for type of deficiency of both QI and YIN, qi stagnation and blood stasis type crowd, effect is remarkable.
Representative instance:
1. go into business certain, man, 53 years old, retired worker.Suffered from diabetes 3 years, chemical examination: glucose in urine (++ ++), blood glucose 9.0mmol/L, myasthenia of limbs, difficulty in walking, xerostomia, polydipsia, polyuria, tentative diagnosis is type Ⅱdiabetes mellitus, and metformin is taken in treatment through many places, and therapeutic effect is not good.In the constant situation of former therapeutic scheme, give compositions auxiliary treatment of the present invention, drink March, the check above-mentioned symptom alleviates to some extent, continues to take compositions of the present invention after February, and the check symptom is clearly better, and can walk voluntarily 300 meters.Continuous take compositions of the present invention after 70 days, xerostomia, polydipsia, polyuria symptom are clearly better, chemical examination: glucose in urine (-) fasting glucose 5.9mmol/L, the 5000m of can walking voluntarily.
2. Lee, man, 52 years old, cadre.Suffered from diabetes 5 years, once medical in People's Hospital of Shanxi Prov., be diagnosed as type Ⅱdiabetes mellitus, hypertension, main stating: headache, dizziness, repeatedly outbreak, polydipsia, polyuria, polyphagia, blood pressure 160/100mmHg, the chemical examination glucose in urine (+++), blood glucose 8.0mmol/L; Take the acarbose blood sugar lowering, the Hypotensor No 0 (Triamterene+Reserpine+Hydrochlorothiazide+Dihydralazine+Chlordiazepoxide) blood pressure lowering, the state of an illness has no and is clearly better.Then add compositions of the present invention, after January, subjective symptoms is alleviated, take March after, the check result of laboratory test, glucose in urine (-), blood glucose 6.0mmol/L, blood pressure 130/90mmHg can work.
3. Zhang, man, 60 years old, cadre, suffer from hypertension, cerebral thrombosis March, the readme dizziness shows effect repeatedly, right side limb adynamia, numbness were once gone to a doctor in 517 Army Hospitals, proved conclusively to be hypertension, coronary atherosclerotic heart disease, high fat of blood, cerebral thrombosis.The chemical examination blood fat: LDL-C 3.5mmol/L, HDL-C 0.9mmol/L, TG2.0mmol/L takes the Drug therapys such as clofibrate, FUFANG JIANGYA PIAN, and the state of an illness has no and is clearly better.Then sb.'s illness took a favorable turn after giving that compositions of the present invention is auxiliary and taking January, and after February, subjective symptoms disappears, the right side limb activity freely, muscular strength is normal, chemical examination blood fat LDL-C 3.0mmol/L, HDL-C 1.2mmol/L, TG1.5mmol/L.
4. Jin, woman, 59 years old.Dizzy over 6 years, cardiopalmus, insomnia, obesity, once in First People's Hospital, Wuzhai County, People's Hospital of Shanxi Prov. is medical, be diagnosed as hyperlipidemia, obesity, hypertension, have a medical check-up: blood pressure 170/90mmHg, chemical examination: blood fat LDL-C 3.6mmol/L took the Drug therapys such as FUFANG LUOBUMA PIAN, simvastatin 3 years, Relapse rate, curative effect are not remarkable, after giving that compositions of the present invention is auxiliary and taking 3 months, above-mentioned symptom alleviates, body weight is fallen 6 kilograms, chemical examination: blood fat LDL-C 2.9mmol/L, blood pressure 130/80 mmHg.The patient is still taking compositions of the present invention at present, and it is normal repeatedly to check blood fat, and controlling of blood pressure is good.
5. Zhang, woman, 60 years old.The right side numb limbs and tense tendons February appears in dizzy, headache, fat 13 years, and is unable.Be diagnosed as on inspection simple obesity, hyperlipidemia, arteriosclerosis, chemical examination: LDL-C 7.0mmol/L, HDL-C 0.7mmol/L, TG 2.1mmol/L, CHO 0.72mmol/L takes Radix Polygoni Multiflori tablet, Xuezhikang, and therapeutic effect is not obvious, after giving that medicine of the present invention is auxiliary and taking June, above-mentioned symptom disappears, chemical examination: LDL-C 3.6mmol/L, HDL-C 1.0mmol/L, TG 1.6mmol/L, CHO 4.5mmol/L.Adhere to using former medicine to cooperate and take compositions of the present invention, follow up a case by regular visits to February, dizzy, not outbreak of headache, blood fat control is good.
6. journey, man 54 years old, main cause is dizzy, fat 3 years, and is once medical in Beijing 301 Hospital in May, 2008, the obesity of having a medical check-up, 86 kilograms of body weight, chemical examination blood fat LDL-C 6.5mmol/L, HDL-C 0.8mmol/L, TG 2.0mmol/L, be diagnosed as hyperlipidemia, simple obesity is taken the fenofibrate state of an illness without being clearly better.Add compositions of the present invention and check after February on the former constant basis of Western medicine that takes, the dizzy disappearance, have a medical check-up: 72 kilograms of body weight, chemical examination blood fat: HDL0.98mmol/L, all the other are every normal.
7. Zheng, woman, 58 years old, main cause is dizzy, fat 3 years, once in First People's Hospital, Wuzhai County, Shanxi Province, People's Hospital of Shanxi Prov. is medical, be diagnosed as Simple Obesity, hyperlipidemia is had a medical check-up 86 kilograms, blood fat: CHO 7.0mmol/L, LDL-C 4.2mmol/L, HDL-C 0.92mmol/L, TG 1.76mmol/L, once took alginate diester and the medicine such as receive, curative effect is not obvious.Then, advise its long-term taking compositions of the present invention taking former medicine basis, dizziness does not show effect in half a year, and further consultation is had a medical check-up: 70 kilograms of body weight, and the chemical examination blood fat is normal, advises it to continue to take, and periodic review is every normal.
8. Liu, woman, 57 years old, main cause is dizzy, fat, easily tired, and once medical in the People's Hospital, Wuzhai County, private prosecution is dizzy, fat, weak, have a medical check-up: 80 kilograms of body weight, chemical examination blood fat LDL-C 3.9mmol/L, TG 2.0mmol/L, tentative diagnosis simple obesity, hyperlipidemia are taken Xuezhikang, have no to be clearly better, doctor's advice is long-term taking compositions of the present invention on the basis of former therapeutic scheme, checks 69 kilograms of body weight after half a year, dizzy, weak disappearance, blood fat is normal.
The specific embodiment
Embodiment 1: every part is 1 gram.
A kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is made by the raw material of following parts by weight, Herba Chlorophyti leaf 1 gram, Herba Chlorophyti 2 grams, Rhizoma Polygonati Odorati 5 grams, Rhizoma Dioscoreae 7 grams, Polyporus 10 grams, Folium Mori 7 grams, Radix Trichosanthis 5 grams.According to the health product processing criterion, it is for oral administration to make various dosage forms, such as tablet with above-mentioned all medicines.
Embodiment 2: every part is 1 jin.
A kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is made by the raw material of following parts by weight, 3 jin on Herba Chlorophyti leaf, 2 jin in Herba Chlorophyti, 7 jin of Rhizoma Polygonati Odorati, 10 jin of Rhizoma Dioscoreaes, 7 jin of Polyporus, 5 jin on Folium Mori, 3 jin of Radix Trichosanthis.According to the health product processing criterion, it is for oral administration to make various dosage forms, such as colloid with above-mentioned all medicines.
Embodiment 3: every part is 1 kilogram.
A kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is made by the raw material of following parts by weight, 1 kilogram on Herba Chlorophyti leaf, 6 kilograms in Herba Chlorophyti, 10 kilograms of Rhizoma Polygonati Odorati, 1 kilogram of Rhizoma Dioscoreae, 3 kilograms of Polyporus, 10 kilograms on Folium Mori, 7 kilograms of Radix Trichosanthis.According to the health product processing criterion, it is for oral administration to make various dosage forms, such as oral agents with above-mentioned all medicines.
Embodiment 4: every part is 1 gram.
A kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is made by the raw material of following parts by weight, Herba Chlorophyti leaf 0.5 gram, Herba Chlorophyti 0.5 gram, Rhizoma Polygonati Odorati 3 grams, Rhizoma Dioscoreae 5 grams, Polyporus 1 gram, Folium Mori 3 grams, Radix Trichosanthis 10 grams.According to the health product processing criterion, it is for oral administration to make various dosage forms, such as drink agent with above-mentioned all medicines.
Embodiment 5: every part is 1 jin.
A kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is made by the raw material of following parts by weight, 9 jin on Herba Chlorophyti leaf, 1 jin in Herba Chlorophyti, 1 jin of Rhizoma Polygonati Odorati, 3 jin of Rhizoma Dioscoreaes, 5 jin of Polyporus, 1 jin on Folium Mori, 1 jin of Radix Trichosanthis.According to the health product processing criterion, it is for oral administration to make various dosage forms, such as tablet with above-mentioned all medicines.
Embodiment 6: every part is 1 kilogram.
A kind of compositions with effects of losing weight and lowering blood sugar and blood lipid is made by the raw material of following parts by weight, 5 kilograms on Herba Chlorophyti leaf, 4 kilograms in Herba Chlorophyti, 10 kilograms of Rhizoma Polygonati Odorati, 10 kilograms of Rhizoma Dioscoreaes, 10 kilograms of Polyporus, 10 kilograms on Folium Mori, 10 kilograms of Radix Trichosanthis.According to the health product processing criterion, it is for oral administration to make various dosage forms, such as oral agents with above-mentioned all medicines.
Claims (2)
1. the compositions with effects of losing weight and lowering blood sugar and blood lipid is characterized in that, is made by the raw material of following parts by weight, with Herba Chlorophyti leaf and flower 1-10 part of any proportioning, Rhizoma Polygonati Odorati 1-10 part, Rhizoma Dioscoreae 1-10 part, Polyporus 1-10 part, Folium Mori 1-10 part, Radix Trichosanthis 1-10 part.
2. a kind of compositions with effects of losing weight and lowering blood sugar and blood lipid according to claim 1 is characterized in that, described compositions is tablet, drink agent.
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| CN103719497B (en) * | 2013-12-31 | 2015-08-12 | 青岛恒波仪器有限公司 | A kind of gynostemma pentaphylla lowering blood-fat and reducing weight health protection tea and preparation method thereof |
| CN104906192A (en) * | 2015-06-05 | 2015-09-16 | 王丹 | Glucose decreasing and thirsty quenching plaster and preparation method thereof |
| CN107456532A (en) * | 2017-03-07 | 2017-12-12 | 许载友 | Fragrant thoroughwort hypoglycemic is clear |
| CN111298018A (en) * | 2020-02-29 | 2020-06-19 | 罗绪洲 | Formula for treating diabetes and preparation method thereof |
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| CN101480473A (en) * | 2008-01-07 | 2009-07-15 | 南京万舜源生物科技有限公司 | Compound recipe for reducing blood sugar as well as preparation method and application |
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| CN101480473A (en) * | 2008-01-07 | 2009-07-15 | 南京万舜源生物科技有限公司 | Compound recipe for reducing blood sugar as well as preparation method and application |
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