CN102492551A - Preparation method for novel long-acting solid aromatic agent - Google Patents
Preparation method for novel long-acting solid aromatic agent Download PDFInfo
- Publication number
- CN102492551A CN102492551A CN2011104325530A CN201110432553A CN102492551A CN 102492551 A CN102492551 A CN 102492551A CN 2011104325530 A CN2011104325530 A CN 2011104325530A CN 201110432553 A CN201110432553 A CN 201110432553A CN 102492551 A CN102492551 A CN 102492551A
- Authority
- CN
- China
- Prior art keywords
- essential oil
- solid aromatic
- new
- making method
- acting solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Fats And Perfumes (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a preparation method for a novel long-acting solid aromatic agent. The method comprises the following steps of: performing inclusion with a microcapsule embedding agent at 30-80 DEG C by taking essential oil as a raw material by using a direct tablet compression technology of micro-encapsulation; uniformly mixing microcapsule essential oil which is obtained by vacuum drying with various tablet auxiliary materials in proportion of 2:3-3:1; and then performing direct tablet compression to obtain solid aromatic agent of which fragrance retaining time is 3-4 hours. Since a fragrance fixative is not used, the method is safe and harmless, meanwhile, liquid-state essential oil solidification is realized, and aromatherapy use of a user is facilitated. The method has the advantages of simple and reliable process flow, short process flow, convenience in operation and no pollution.
Description
Technical field
The invention relates to a kind of making method of aromatic props, be meant a kind of making method of New-type long-acting solid aromatic body especially.
Background technology
Aromatotherapy is to utilize the aromatic odour of natural plant essential oils and other compositions, and through olfactory organ and skin absorption, the system that affects the nerves and blood circulation are to realize the adjusting to human body mood and physiological conditions.In the conventional fragrant therapy, often use liquid essential oil to make essential oil be diffused into air, and then reach the purpose that makes the human body detected by scent through special-purpose perfume fumigator heating.Owing to use liquid essential oil, make that to there is the essential oil allotment loaded down with trivial details, carry inconvenience, the fragrance time is short, be difficult to shortcoming such as cleaning, can't satisfy to be in height stress modern, especially working clan down, and relief pressure is at any time enjoyed the demand of fragrant treatment enjoyment.
And way commonly used at present is essential oil to be added drop-wise to carriers such as the scraps of paper, cotton paper, adds fragrance fixating agent simultaneously to reach the purpose that prolongs fragrance remaining time.But because this type carrier absorption essential oil amount is limited, and fragrance fixating agent is harmful to HUMAN HEALTH.Like fragrance fixating agent---diethyl phthalate commonly used, be a kind of fluidizer, after taking in, human body can endanger male reproductive function, impel women's sexual prematurity, long-term huge uptake may cause liver cancer.In view of this, this case just produces thus.
Summary of the invention
The object of the present invention is to provide and a kind ofly can realize that liquid essential oil solidifies down, the essential oil embedding is stable, embedding efficiency is high, the making method of the New-type long-acting solid aromatic body of had good sustained release effect, the simple and suitable large-scale production of technology.
For realizing above-mentioned purpose, solution of the present invention is:
A kind of making method of New-type long-acting solid aromatic body, concrete steps are:
The pre-treatment of step 1, essential oil: directly be dissolved in essential oil in the solvent by 1:10 ~ 1:30;
Step 2, with microcapsule embedded dose saturated in warm water, the essential oil of anticipating is slowly joined in the microcapsule embedded agent solution, and is positioned under 30～80 ℃ of constant temperature and stirs inclusion; Be positioned over cooling under the normal temperature after the inclusion, move into 0～4 ℃ of refrigeration 12～24h down; Take out afterwards with B device vacuum filtration, do not have moisture, filter cake is taken out move into vacuum drying oven until surface drying, dry at normal temperatures; The tiling of microencapsulated essential oils porphyrize after the vacuum-drying is placed the dry 24h of moisture eliminator, obtain microencapsulated essential oils;
Step 3, with microencapsulated essential oils and multiple auxiliary material in the ratio mixing of 2:3 ~ 3:1, sieve, compressing tablet promptly gets long-acting solid fragrance body.
The time of stirring inclusion in the said step 2 is 0.5 ~ 3h.
In the said step 2 under the normal temperature exsiccant time be 1.5 ~ 2.5h.
The essential oil of said step 1 is natural perfume such as lemon quintessence oil, Herba Lysimachiae foenumgraeci quintessence oil, rhodamine b extra 500 wet goods; Or the essence and flavoring agent of synthetic.
The solvent of said step 1 is to have the solvent that the essential oil dissolving is easy to realize embedding, like absolute ethyl alcohol, 95% ethanol or methyl alcohol.
Microcapsule embedded dose of said step 2 is starch, modified starch, starch-based composition, vegetable jelly, cellulose acetate, Vltra tears, whey-protein etc.
The auxiliary material of said step 3 is Microcrystalline Cellulose, starch, Magnesium Stearate, pregelatinized Starch, secondary calcium phosphate, calcium sulfate, lactose, micropowder silica gel, Povidone, USP/EP, gelatin, sucrose etc.
Said step 3 is that the Microcrystalline Cellulose of 50% ~ 70% micro encapsulation citrus or fragrance of a flower class or vanilla class essential oil and 20% ~ 30%, 5 ~ 15% pregelatinized Starch, 0.5 ~ 1% Magnesium Stearate are crossed 80 mesh sieves respectively; Add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.
Said step 3 is that 45 ~ 52% micro encapsulation camphor class or hot fragrant type essential oil, 30 ~ 40% calcium sulfate, 7 ~ 24% Microcrystalline Cellulose, 0.5 ~ 1% Magnesium Stearate are crossed 80 mesh sieves respectively; Add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.
Said step 3 is that 60 ~ 70% micro encapsulation resene or wooden type or soil property class essential oil, 18 ~ 24% secondary calcium phosphate, 7 ~ 15% lactose, 0.5 ~ 1% Magnesium Stearate are crossed 80 mesh sieves respectively; Add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.
After adopting such scheme, the New-type long-acting solid essential oil of this patent fragrance body, essential oil is realized the purpose of solid, safety (not adding any fragrance fixating agent), slowly-releasing after embedding, to substitute liquid essential oil; Fragrant body of the present invention not only can apply to traditional perfume fumigator (remove from add water trouble), also can apply to variously have novel electrically heated perfume fumigator, as long as there is thermal source just can carry out champignon, uses unrestricted; Allotment is easy between multiple essential oil simultaneously, and only need different sorts essential oil fragrance body be put together gets final product, and brings the human consumer more enjoyment of allocating personally.And this solid essential oil product fragrance RT on fumigator reaches 3 ~ 4 hours; It can be sheet, particulate state or other solid shape.
Advantage of the present invention: technical process is simple, reliable; Easy to carry, fragrance remaining time is long; Do not contain fragrance fixating agent, safe in utilization; The essential oil allotment of different aromas and effect has the enjoyment of allotment personally easily.
Embodiment
Below in conjunction with specific examples the present invention is described in detail.
Essential oil can roughly be divided into following several types according to smell:
Citrus: essential oils such as Fructus Citri Sarcodactylis, natsudaidai, lemon, lime, tangerine, sweet orange, bigarabe, shaddock, flores aurantii, orange leaf;
Fragrance of a flower class: essential oils such as Flos Pelargonii, Flos Matricariae chamomillae, rose, lavandula angustifolia, Yilan, Yilan;
Vanilla class: peppermint, Rosmarinus officinalis, marjoram, come essential oils such as Salvia japonica Thunb. soon;
Camphor class: essential oils such as eucalyptus globolus, Punetree, tea tree;
Hot fragrant type: essential oils such as coriander, piper nigrum, ginger, Semen Myristicae;
Resene: essential oils such as frankincense, elemi, myrrh, galbanum;
Wooden type: essential oils such as cdear, sandalwood, pine, juniper berry, cypress;
Soil property class: essential oils such as Wrinkled Gianthyssop Herb, Vetiveria zizanoides;
Certainly, a kind of classification more than the essential oil smell that has can surpass.
Instance 1
1, the pre-treatment of lemon quintessence oil:
Take by weighing the 20g lemon quintessence oil, lemon quintessence oil is dissolved in the absolute ethyl alcohol in the ratio of 1:20.
2, the preparation of solid essential oil powder:
Accurately measure 1000mL zero(ppm) water and be heated to 50 ℃ of constant temperature preservations; Taking by weighing the 56g cycloheptaamylose then pours in the water; After constantly stirring is treated to dissolve fully, the lemon quintessence oil of anticipating is slowly joined in the cycloheptaamylose solution, and be positioned over stirring inclusion 2h under 50 ℃ of constant temperature.Be positioned over cooling under the normal temperature after the inclusion, move into 0～4 ℃ of refrigeration 12h down.Take out afterwards with B device vacuum filtration, do not have moisture, filter cake is taken out move into vacuum drying oven, dry at normal temperatures 2h until surface drying.The tiling of microencapsulated essential oils porphyrize after the vacuum-drying is placed the dry 24h of moisture eliminator, obtain microencapsulated essential oils.
3, the compacting of solid essential oil sheet:
Micro encapsulation lemon quintessence oil with 60% and 30% Microcrystalline Cellulose, 9% pregelatinized Starch, 1% Magnesium Stearate are crossed 80 mesh sieves respectively, add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.The solid essential oil sheet of above-mentioned gained has obvious citris aromas, and on fumigator, the time length of fragrance can continue 3 ~ 4h.
Instance 2
1, the pre-treatment of tea tree ethereal oil:
Take by weighing the 30g tea tree ethereal oil, tea tree ethereal oil is dissolved in the absolute ethyl alcohol in the ratio of 1:30.
2, the preparation of solid essential oil powder:
Accurately measure 1000mL zero(ppm) water and be heated to 50 ℃ of constant temperature preservations; Taking by weighing the 56g cycloheptaamylose then pours in the water; After constantly stirring is treated to dissolve fully, the Flos Pelargonii essential oil of anticipating is slowly joined in the cycloheptaamylose solution, and be positioned over stirring inclusion 2h under 45 ℃ of constant temperature.Be positioned over cooling under the normal temperature after the inclusion, move into 0～4 ℃ of refrigeration 12h down.Take out afterwards with B device vacuum filtration, do not have moisture, filter cake is taken out move into vacuum drying oven, dry at normal temperatures 2h until surface drying.The tiling of microencapsulated essential oils porphyrize after the vacuum-drying is placed the dry 24h of moisture eliminator, obtain microencapsulated essential oils.
3, the compacting of solid essential oil sheet:
Micro encapsulation tea tree ethereal oil with 50%, 30% calcium sulfate, 10% Microcrystalline Cellulose, 9% pregelatinized Starch, 1% Magnesium Stearate are crossed 80 mesh sieves respectively, add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.The solid essential oil sheet of above-mentioned gained has strong tea tree fragrance, and on fumigator, the time length of fragrance can continue 3 ~ 4h.
Instance 3
1, the pre-treatment of cdear essential oil:
Take by weighing 20g cdear essential oil, Herba Lysimachiae foenumgraeci quintessence oil is dissolved in the absolute ethyl alcohol in the ratio of 1:10.
2, the preparation of solid essential oil powder:
Take by weighing the 50g modified starch with the dissolving of 40 ℃ warm water, the cdear essential oil of anticipating is slowly joined in the modified starch solution, and be positioned over stirring inclusion 2h 45 ℃ of constant temperature under.Be positioned over cooling under the normal temperature after the inclusion, move into 0～4 ℃ of refrigeration 12h down.Take out afterwards with B device vacuum filtration, do not have moisture, filter cake is taken out move into vacuum drying oven, dry at normal temperatures 2h until surface drying.The tiling of microencapsulated essential oils porphyrize after the vacuum-drying is placed the dry 24h of moisture eliminator, obtain microencapsulated essential oils.
3, the compacting of solid essential oil sheet:
Micro encapsulation cdear essential oil with 65%, 24% secondary calcium phosphate, 10% lactose, 1% Magnesium Stearate are crossed 80 mesh sieves respectively, add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.The solid essential oil sheet of above-mentioned gained has strong cdear fragrance, and on fumigator, the time length of fragrance can continue 3 ~ 4h.
Claims (10)
1. the making method of a New-type long-acting solid aromatic body, concrete steps are:
The pre-treatment of step 1, essential oil: directly be dissolved in essential oil in the solvent by 1:10 ~ 1:30;
Step 2, with microcapsule embedded dose saturated in warm water, the essential oil of anticipating is slowly joined in the microcapsule embedded agent solution, and is positioned under 30～80 ℃ of constant temperature and stirs inclusion; Be positioned over cooling under the normal temperature after the inclusion, move into 0～4 ℃ of refrigeration 12～24h down; Take out afterwards with B device vacuum filtration, do not have moisture, filter cake is taken out move into vacuum drying oven until surface drying, dry at normal temperatures; The tiling of microencapsulated essential oils porphyrize after the vacuum-drying is placed the dry 24h of moisture eliminator, obtain microencapsulated essential oils;
Step 3, with microencapsulated essential oils and multiple auxiliary material in the ratio mixing of 2:3 ~ 3:1, sieve, compressing tablet promptly gets long-acting solid fragrance body.
2. the making method of a kind of New-type long-acting solid aromatic body according to claim 1 is characterized in that: the time of stirring inclusion in the said step 2 is 0.5 ~ 3h.
3. the making method of a kind of New-type long-acting solid aromatic body according to claim 1 is characterized in that: in the said step 2 under the normal temperature exsiccant time be 1.5 ~ 2.5h.
4. the making method of a kind of New-type long-acting solid aromatic body according to claim 1 is characterized in that: the essential oil of said step 1 is the essence and flavoring agent of natural perfume or synthetic.
5. the making method of a kind of New-type long-acting solid aromatic body according to claim 1 is characterized in that: the solvent of said step 1 is absolute ethyl alcohol, 95% ethanol or methyl alcohol.
6. the making method of a kind of New-type long-acting solid aromatic body according to claim 1 is characterized in that: microcapsule embedded dose of said step 2 is starch, modified starch, starch-based composition, vegetable jelly, cellulose acetate, Vltra tears or whey-protein.
7. the making method of a kind of New-type long-acting solid aromatic body according to claim 1 is characterized in that: the auxiliary material of said step 3 is Microcrystalline Cellulose, starch, Magnesium Stearate, pregelatinized Starch, secondary calcium phosphate, calcium sulfate, lactose, micropowder silica gel, Povidone, USP/EP, gelatin or sucrose.
8. the making method of a kind of New-type long-acting solid aromatic body according to claim 1; It is characterized in that: said step 3 is that the Microcrystalline Cellulose of 50% ~ 70% micro encapsulation citrus or fragrance of a flower class or vanilla class essential oil and 20% ~ 30%, 5 ~ 15% pregelatinized Starch, 0.5 ~ 1% Magnesium Stearate are crossed 80 mesh sieves respectively; Add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.
9. the making method of a kind of New-type long-acting solid aromatic body according to claim 1; It is characterized in that: said step 3 is that 45 ~ 52% micro encapsulation camphor class or hot fragrant type essential oil, 30 ~ 40% calcium sulfate, 7 ~ 24% Microcrystalline Cellulose, 0.5 ~ 1% Magnesium Stearate are crossed 80 mesh sieves respectively; Add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.
10. the making method of a kind of New-type long-acting solid aromatic body according to claim 1; It is characterized in that: said step 3 is that 60 ~ 70% micro encapsulation resene or wooden type or soil property class essential oil, 18 ~ 24% secondary calcium phosphate, 7 ~ 15% lactose, 0.5 ~ 1% Magnesium Stearate are crossed 80 mesh sieves respectively; Add small-sized mixer thorough mixing, use Singlepunchtabletpress to carry out compressing tablet then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104325530A CN102492551A (en) | 2011-12-21 | 2011-12-21 | Preparation method for novel long-acting solid aromatic agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104325530A CN102492551A (en) | 2011-12-21 | 2011-12-21 | Preparation method for novel long-acting solid aromatic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102492551A true CN102492551A (en) | 2012-06-13 |
Family
ID=46184415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011104325530A Pending CN102492551A (en) | 2011-12-21 | 2011-12-21 | Preparation method for novel long-acting solid aromatic agent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102492551A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877601A (en) * | 2014-03-25 | 2014-06-25 | 湖北科田植萃精华有限公司 | Extracted plant essence ventilation tablet and preparation method thereof |
| CN104962391A (en) * | 2015-06-05 | 2015-10-07 | 云南瑞升烟草技术（集团）有限公司 | Tobacco solid flavor prepared by using combined microwave technology and application thereof |
| CN113274533A (en) * | 2021-04-20 | 2021-08-20 | 淮阴工学院 | Method for preparing green long-acting portable solid fragrance agent |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1679719A (en) * | 2005-02-03 | 2005-10-12 | 张红军 | Compound zedoary oil oral preparation and production thereof |
| CN1907150A (en) * | 2006-08-11 | 2007-02-07 | 云南瑞升烟草技术（集团）有限公司 | Solidified essence and flavoring agent for cigarette and its preparing process |
| CN101946811A (en) * | 2010-08-26 | 2011-01-19 | 天津绿新低温科技有限公司 | Microencapsulated botanical insect-resist agent |
| CN101965863A (en) * | 2010-08-26 | 2011-02-09 | 天津绿新低温科技有限公司 | Fruit and vegetable micro encapsulated fresh-keeping agent and preparation method thereof |
-
2011
- 2011-12-21 CN CN2011104325530A patent/CN102492551A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1679719A (en) * | 2005-02-03 | 2005-10-12 | 张红军 | Compound zedoary oil oral preparation and production thereof |
| CN1907150A (en) * | 2006-08-11 | 2007-02-07 | 云南瑞升烟草技术（集团）有限公司 | Solidified essence and flavoring agent for cigarette and its preparing process |
| CN101946811A (en) * | 2010-08-26 | 2011-01-19 | 天津绿新低温科技有限公司 | Microencapsulated botanical insect-resist agent |
| CN101965863A (en) * | 2010-08-26 | 2011-02-09 | 天津绿新低温科技有限公司 | Fruit and vegetable micro encapsulated fresh-keeping agent and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 《海南师范学院学报(自然科学版)》 20040930 刘红等,1 香茅油beta-环糊精包合工艺条件的探讨 第254-257页 1-10 第17卷, 第03期 * |
| 刘红等,1: "香茅油β-环糊精包合工艺条件的探讨", 《海南师范学院学报(自然科学版)》, vol. 17, no. 03, 30 September 2004 (2004-09-30), pages 254 - 257 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877601A (en) * | 2014-03-25 | 2014-06-25 | 湖北科田植萃精华有限公司 | Extracted plant essence ventilation tablet and preparation method thereof |
| CN104962391A (en) * | 2015-06-05 | 2015-10-07 | 云南瑞升烟草技术（集团）有限公司 | Tobacco solid flavor prepared by using combined microwave technology and application thereof |
| CN113274533A (en) * | 2021-04-20 | 2021-08-20 | 淮阴工学院 | Method for preparing green long-acting portable solid fragrance agent |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102488585B (en) | Heating patch | |
| CN103316078B (en) | Sleep aiding and cooling patch and preparation method thereof | |
| CN104174056B (en) | Formaldehyde-removal traditional Chinese medicine solid air refresher | |
| CN102492551A (en) | Preparation method for novel long-acting solid aromatic agent | |
| CN108815028A (en) | A kind of skin plant extraction liquid and preparation method thereof | |
| CN106466331A (en) | Comprise the compositionss of yellow paint wood extract | |
| CN108524336A (en) | A kind of Fatsia japonica natural activity face cream and preparation method thereof | |
| CN106580775A (en) | Preparation method of long-lasting refreshing consciousness-restoring balsam | |
| CN102905686B (en) | Skin temperature elevating agents and the cosmetics containing this skin temperature elevating agents, food and groceries | |
| CN105342926A (en) | Herbal floral water | |
| CN104383551A (en) | Traditional Chinese medicine soft capsule auxiliary material with universality and method for preparing traditional Chinese medicine soft capsules | |
| CN108714117B (en) | Long-acting perfume and preparation method thereof | |
| CN103436373A (en) | Mosquito repelling health-care candle | |
| CN101088567A (en) | Moisture-proof deodorant and its prepn process | |
| CN105055235A (en) | Scar removing emulsion | |
| CN105381487A (en) | Incense capable of expelling wind and removing cold and preparation method thereof | |
| CN102133418A (en) | Effective aromatherapy piece made from flos chrysanthemi indici bud and preparation method thereof | |
| CN105434264A (en) | Motherwort-herb toothpaste | |
| CN106234471A (en) | A kind of Folium Artemisiae Argyi anophelifuge pastil and preparation method thereof | |
| CN105687568A (en) | Sleeping-aid incense | |
| CN105769704A (en) | Skincare mask based on active ingredients of staminate flowers of eucommia ulmoides and preparation method of skincare mask | |
| CN104739952A (en) | Compound tea tree essential oil with effect of promoting wound healing | |
| CN1153055A (en) | Chinese medicinal herb coat aerosol for treatment of mild burn scald, soft tissue damage and frostbite | |
| CN103356448A (en) | Five-color flower facial mask | |
| CN101467952A (en) | Novel health massage skin-protection essential oil and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120613 |