CN102458531B - 两种或更多种药物通过单一剂量选择和配给接口的递送 - Google Patents

两种或更多种药物通过单一剂量选择和配给接口的递送 Download PDF

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Publication number
CN102458531B
CN102458531B CN201080033637.0A CN201080033637A CN102458531B CN 102458531 B CN102458531 B CN 102458531B CN 201080033637 A CN201080033637 A CN 201080033637A CN 102458531 B CN102458531 B CN 102458531B
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CN
China
Prior art keywords
drug
medicament
dose
reservoir
user
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080033637.0A
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English (en)
Chinese (zh)
Other versions
CN102458531A (zh
Inventor
D.T.德索斯马雷兹林特尔
M.S.博伊德
D.M.利克
C.P.基廷
D.桑德斯
E.A.马沙尔
G.杰伊
R.D.L.麦克阿瑟
M.J.D.希尔德
C.J.史密斯
E.L.奥蒂兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CN102458531A publication Critical patent/CN102458531A/zh
Application granted granted Critical
Publication of CN102458531B publication Critical patent/CN102458531B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3142—Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN201080033637.0A 2009-06-02 2010-06-01 两种或更多种药物通过单一剂量选择和配给接口的递送 Expired - Fee Related CN102458531B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18345209P 2009-06-02 2009-06-02
US61/183,452 2009-06-02
EP09009657 2009-07-25
EP09009657.9 2009-07-25
PCT/EP2010/057571 WO2010139666A1 (en) 2009-06-02 2010-06-01 Delivery of two or more medicaments through a single dose selection and dispense interface

Publications (2)

Publication Number Publication Date
CN102458531A CN102458531A (zh) 2012-05-16
CN102458531B true CN102458531B (zh) 2014-08-20

Family

ID=41256091

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080033637.0A Expired - Fee Related CN102458531B (zh) 2009-06-02 2010-06-01 两种或更多种药物通过单一剂量选择和配给接口的递送

Country Status (12)

Country Link
US (1) US9592342B2 (https=)
EP (1) EP2437818B1 (https=)
JP (1) JP5823955B2 (https=)
CN (1) CN102458531B (https=)
AR (1) AR076623A1 (https=)
AU (1) AU2010255841B2 (https=)
BR (1) BRPI1012573A2 (https=)
CA (1) CA2763613A1 (https=)
IL (1) IL216569A (https=)
IN (1) IN2011CN08926A (https=)
TW (1) TW201109060A (https=)
WO (1) WO2010139666A1 (https=)

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JP3993169B2 (ja) 2002-02-11 2007-10-17 アンタレス・ファーマ・インコーポレーテッド 皮内注射器
JP5216328B2 (ja) 2005-01-24 2013-06-19 アンタレス ファーマ インコーポレイテッド あらかじめ充填された針補助シリンジジェット式注射器
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
EP2268342B1 (en) 2008-03-10 2015-09-16 Antares Pharma, Inc. Injector safety device
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
SG181420A1 (en) * 2009-10-30 2012-07-30 Revance Therapeutics Inc Device and method for topical application of therapeutics or cosmetic compositions
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
EP2750741A1 (en) 2011-08-30 2014-07-09 Novo Nordisk A/S Arrangement for sequential delivery of fluid volumes
EP2785400A2 (en) 2011-12-01 2014-10-08 Novo Nordisk A/S Drug filled delivery assembly
WO2013134244A2 (en) 2012-03-06 2013-09-12 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
EP4501376A3 (en) * 2012-08-08 2025-04-16 Sanofi-Aventis Deutschland GmbH Drug delivery device with tamper-evident closure
ES2969984T3 (es) 2013-02-11 2024-05-23 Antares Pharma Inc Dispositivo de inyección por chorro asistido por aguja que tiene fuerza de disparo reducida
JP6030803B2 (ja) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド ピニオンシステムを有する用量注射器
JP6810031B2 (ja) 2014-10-29 2021-01-06 ウォックハート リミテッドＷｏｃｋｈａｒｄｔ Ｌｉｍｉｔｅｄ ユーザ操作可能な可変用量ロッキング機構を有する独立してユーザ選択可能な２つ以上の複数用量の薬剤を送達するための薬品送達装置
EP3106200A1 (en) 2015-06-19 2016-12-21 MedTrace A/S A system for safe radioisotope preparation and injection
WO2017191305A1 (en) * 2016-05-06 2017-11-09 Sanofi-Aventis Deutschland Gmbh Injector assembly
CN112437678A (zh) * 2018-05-04 2021-03-02 先进医疗解决方案以色列(西兰迪斯)公司 重构和混合系统

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Publication number Priority date Publication date Assignee Title
US3563240A (en) * 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
US5281198A (en) * 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
CN1507360A (zh) * 2000-05-22 2004-06-23 �ź㴫 医用装置
US20040133163A1 (en) * 2001-06-20 2004-07-08 Frank Schiffmann Device for administering an injectable product in doses

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US3911916A (en) * 1971-10-29 1975-10-14 Peter A Stevens Sequential injection syringe
AT341649B (de) * 1975-08-07 1978-02-27 Immuno Ag Injektionsspritze
US4055177A (en) * 1976-05-28 1977-10-25 Cohen Milton J Hypodermic syringe
JPS5898932U (ja) * 1981-12-28 1983-07-05 市川　今朝登 注射筒
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
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CZ282096B6 (cs) 1992-12-01 1997-05-14 Tetsuro Higashikawa Injekční stříkačka
US5584815A (en) * 1993-04-02 1996-12-17 Eli Lilly And Company Multi-cartridge medication injection device
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ATE339980T1 (de) * 2000-06-08 2006-10-15 Meridian Medical Technologies Automatische injektionsvorrichtung mit trockner und flüssiger komponente
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EP2134388B1 (en) 2007-03-07 2012-12-19 Novo Nordisk A/S A medication delivery device comprising a plurality of reservoirs
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Publication number Priority date Publication date Assignee Title
US3563240A (en) * 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
US5281198A (en) * 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
CN1507360A (zh) * 2000-05-22 2004-06-23 �ź㴫 医用装置
US20040133163A1 (en) * 2001-06-20 2004-07-08 Frank Schiffmann Device for administering an injectable product in doses

Also Published As

Publication number Publication date
IL216569A0 (en) 2012-03-01
AU2010255841B2 (en) 2015-05-28
CA2763613A1 (en) 2010-12-09
IN2011CN08926A (https=) 2015-08-21
JP2012528634A (ja) 2012-11-15
US9592342B2 (en) 2017-03-14
TW201109060A (en) 2011-03-16
BRPI1012573A2 (pt) 2016-03-29
EP2437818A1 (en) 2012-04-11
WO2010139666A1 (en) 2010-12-09
AR076623A1 (es) 2011-06-22
AU2010255841A1 (en) 2011-12-22
IL216569A (en) 2015-07-30
US20120136334A1 (en) 2012-05-31
JP5823955B2 (ja) 2015-11-25
EP2437818B1 (en) 2019-12-11
CN102458531A (zh) 2012-05-16

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Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140820

Termination date: 20200601