CN102458531B - 两种或更多种药物通过单一剂量选择和配给接口的递送 - Google Patents

两种或更多种药物通过单一剂量选择和配给接口的递送 Download PDF

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Publication number
CN102458531B
CN102458531B CN201080033637.0A CN201080033637A CN102458531B CN 102458531 B CN102458531 B CN 102458531B CN 201080033637 A CN201080033637 A CN 201080033637A CN 102458531 B CN102458531 B CN 102458531B
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CN
China
Prior art keywords
medicine
dose
memory
main memory
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080033637.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN102458531A (zh
Inventor
D.T.德索斯马雷兹林特尔
M.S.博伊德
D.M.利克
C.P.基廷
D.桑德斯
E.A.马沙尔
G.杰伊
R.D.L.麦克阿瑟
M.J.D.希尔德
C.J.史密斯
E.L.奥蒂兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CN102458531A publication Critical patent/CN102458531A/zh
Application granted granted Critical
Publication of CN102458531B publication Critical patent/CN102458531B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3142—Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN201080033637.0A 2009-06-02 2010-06-01 两种或更多种药物通过单一剂量选择和配给接口的递送 Expired - Fee Related CN102458531B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18345209P 2009-06-02 2009-06-02
US61/183,452 2009-06-02
EP09009657 2009-07-25
EP09009657.9 2009-07-25
PCT/EP2010/057571 WO2010139666A1 (en) 2009-06-02 2010-06-01 Delivery of two or more medicaments through a single dose selection and dispense interface

Publications (2)

Publication Number Publication Date
CN102458531A CN102458531A (zh) 2012-05-16
CN102458531B true CN102458531B (zh) 2014-08-20

Family

ID=41256091

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080033637.0A Expired - Fee Related CN102458531B (zh) 2009-06-02 2010-06-01 两种或更多种药物通过单一剂量选择和配给接口的递送

Country Status (12)

Country Link
US (1) US9592342B2 (enExample)
EP (1) EP2437818B1 (enExample)
JP (1) JP5823955B2 (enExample)
CN (1) CN102458531B (enExample)
AR (1) AR076623A1 (enExample)
AU (1) AU2010255841B2 (enExample)
BR (1) BRPI1012573A2 (enExample)
CA (1) CA2763613A1 (enExample)
IL (1) IL216569A (enExample)
IN (1) IN2011CN08926A (enExample)
TW (1) TW201109060A (enExample)
WO (1) WO2010139666A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003209095A1 (en) 2002-02-11 2003-09-04 Antares Pharma, Inc. Intradermal injector
DK1850892T4 (da) 2005-01-24 2023-06-06 Antares Pharma Inc Forfyldt nål-assisteret sprøjtejetinjektor
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
US8814834B2 (en) 2008-03-10 2014-08-26 Antares Pharma, Inc. Injector safety device
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
MX2012005115A (es) * 2009-10-30 2012-06-19 Revance Therapeutics Inc Dispositivo y metodo para la aplicacion topica de composiciones terapeuticas o cosmeticas.
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
EP2750741A1 (en) 2011-08-30 2014-07-09 Novo Nordisk A/S Arrangement for sequential delivery of fluid volumes
US9889258B2 (en) 2011-12-01 2018-02-13 Novo Nordisk A/S Drug filled delivery assembly
KR20150003179A (ko) 2012-03-06 2015-01-08 안타레스 팔마, 인코퍼레이티드 분리력 특징을 가진 사전충전형 주사기
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
WO2013169804A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
EP4501376A3 (en) * 2012-08-08 2025-04-16 Sanofi-Aventis Deutschland GmbH Drug delivery device with tamper-evident closure
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
EP3572108A1 (en) 2013-03-11 2019-11-27 Antares Pharma, Inc. Dosage injector with pinion system
WO2016067179A1 (en) 2014-10-29 2016-05-06 Wockhardt Limited A drug delivery device for delivery of two or more independently user selectable multiple doses of medicaments with user operable variable dose locking mechanisms
EP3106200A1 (en) 2015-06-19 2016-12-21 MedTrace A/S A system for safe radioisotope preparation and injection
US11103648B2 (en) 2016-05-06 2021-08-31 Sanofi-Aventis Deutschland Gmbh Injector assembly
CN112437678A (zh) * 2018-05-04 2021-03-02 先进医疗解决方案以色列(西兰迪斯)公司 重构和混合系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3563240A (en) * 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
US5281198A (en) * 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
CN1507360A (zh) * 2000-05-22 2004-06-23 �ź㴫 医用装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3911916A (en) * 1971-10-29 1975-10-14 Peter A Stevens Sequential injection syringe
AT341649B (de) * 1975-08-07 1978-02-27 Immuno Ag Injektionsspritze
US4055177A (en) * 1976-05-28 1977-10-25 Cohen Milton J Hypodermic syringe
JPS5898932U (ja) * 1981-12-28 1983-07-05 市川　今朝登 注射筒
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4857056A (en) * 1988-07-06 1989-08-15 Sherwood Medical Company Auto-flush syringe pump
US5114411A (en) * 1990-11-19 1992-05-19 Habley Medical Technology Corporation Multi-chamber vial
US5147323A (en) * 1991-03-08 1992-09-15 Habley Medical Technology Corporation Multiple cartridge syringe
US5423752A (en) * 1992-07-31 1995-06-13 Habley Medical Technology Corporation Variable proportion dispenser with cartridge replacement assembly
SK279863B6 (sk) 1992-12-01 1999-04-13 Tetsuro Higashikawa Injekčná striekačka
US5584815A (en) * 1993-04-02 1996-12-17 Eli Lilly And Company Multi-cartridge medication injection device
US5681279A (en) * 1996-11-04 1997-10-28 Roper; David H. Pill dispensing syringe
CA2362260C (en) * 1999-02-16 2009-05-12 Michael A. Taylor Single dose delivery device
US6527738B1 (en) * 1999-04-30 2003-03-04 Prismedical Corporation Drug delivery pack
US6689101B2 (en) * 2000-05-22 2004-02-10 Pharmacia Ab Medical arrangement
CA2412420C (en) * 2000-06-08 2008-12-02 Meridian Medical Technologies, Inc. Wet/dry automatic injector assembly
DE10129585A1 (de) 2001-06-20 2003-01-09 Disetronic Licensing Ag Vorrichtung für eine dosierte Verabreichung eines injizierbaren Produkts
US20070100288A1 (en) 2003-06-05 2007-05-03 University Of Florida Research Foundation, Inc. Auto-injection devices and methods for intramuscular administration of medications
US7645264B2 (en) * 2005-04-11 2010-01-12 Becton, Dickinson And Company Injection device with secondary reservoir
ITPD20060419A1 (it) * 2006-11-13 2008-05-14 Federico Nalesso Dispositivo per il trattamento manutentivo di cateteri venosi centrali
JP2010519993A (ja) 2007-03-07 2010-06-10 ノボ・ノルデイスク・エー／エス 複数のリザーバを備える薬剤送達デバイス
US20080306439A1 (en) 2007-06-08 2008-12-11 Nelson M Bud Devices for mixing and applying a fluid composition
JP5898932B2 (ja) 2011-11-29 2016-04-06 株式会社イトーキ 二重床パネル構造

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3563240A (en) * 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
US5281198A (en) * 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
CN1507360A (zh) * 2000-05-22 2004-06-23 �ź㴫 医用装置

Also Published As

Publication number Publication date
TW201109060A (en) 2011-03-16
CA2763613A1 (en) 2010-12-09
IN2011CN08926A (enExample) 2015-08-21
AR076623A1 (es) 2011-06-22
CN102458531A (zh) 2012-05-16
BRPI1012573A2 (pt) 2016-03-29
US9592342B2 (en) 2017-03-14
JP2012528634A (ja) 2012-11-15
WO2010139666A1 (en) 2010-12-09
EP2437818A1 (en) 2012-04-11
AU2010255841A1 (en) 2011-12-22
EP2437818B1 (en) 2019-12-11
US20120136334A1 (en) 2012-05-31
JP5823955B2 (ja) 2015-11-25
AU2010255841B2 (en) 2015-05-28
IL216569A (en) 2015-07-30
IL216569A0 (en) 2012-03-01

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140820

Termination date: 20200601

CF01 Termination of patent right due to non-payment of annual fee