CN102439441B - 用于肾损伤和肾衰竭的诊断及预后方法和组合物 - Google Patents

用于肾损伤和肾衰竭的诊断及预后方法和组合物 Download PDF

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Publication number
CN102439441B
CN102439441B CN201080014932.1A CN201080014932A CN102439441B CN 102439441 B CN102439441 B CN 102439441B CN 201080014932 A CN201080014932 A CN 201080014932A CN 102439441 B CN102439441 B CN 102439441B
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renal
threshold
concentration
likelihood
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Chinese (zh)
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CN102439441A (zh
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J·安德贝里
J·格雷
P·麦克弗森
K·中村
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Astute Medical Inc
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Astute Medical Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201080014932.1A 2009-02-06 2010-02-05 用于肾损伤和肾衰竭的诊断及预后方法和组合物 Expired - Fee Related CN102439441B (zh)

Applications Claiming Priority (3)

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US15039509P 2009-02-06 2009-02-06
US16241509P 2009-03-23 2009-03-23
PCT/US2010/023297 WO2010091236A1 (en) 2009-02-06 2010-02-05 Methods and compositions for diagnosis and prognosis of renal injury and failure

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CN102439441A CN102439441A (zh) 2012-05-02
CN102439441B true CN102439441B (zh) 2016-03-09

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Country Link
US (1) US20120053072A1 (https=)
EP (1) EP2394166B1 (https=)
JP (1) JP2012517594A (https=)
CN (1) CN102439441B (https=)
AU (1) AU2010210540B2 (https=)
CA (1) CA2751435A1 (https=)
NZ (2) NZ601575A (https=)
WO (1) WO2010091236A1 (https=)

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EP2324354B1 (en) 2008-08-29 2014-07-16 Astute Medical, Inc. Methods for prognosis of acute renal failure
ES2836218T3 (es) 2008-10-21 2021-06-24 Astute Medical Inc Procedimientos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
EP2913676A1 (en) 2008-11-10 2015-09-02 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AU2010279249B2 (en) 2009-02-06 2015-08-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AU2010315008B2 (en) 2009-11-07 2015-12-03 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2011075744A1 (en) 2009-12-20 2011-06-23 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AU2011213684B2 (en) 2010-02-05 2014-11-20 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ701807A (en) 2010-02-26 2015-05-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
IN2012MN02812A (https=) 2010-06-23 2015-05-22 Astute Medical Inc
NZ605698A (en) 2010-06-23 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US20130316370A1 (en) * 2010-10-07 2013-11-28 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2012094658A2 (en) * 2011-01-08 2012-07-12 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2012103450A2 (en) 2011-01-29 2012-08-02 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
TW201250248A (en) * 2011-04-25 2012-12-16 Kyowa Medex Co Ltd Prognostication method of renal failure
US10935548B2 (en) 2011-12-08 2021-03-02 Astute Medical, Inc. Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2
WO2013130591A1 (en) * 2012-02-27 2013-09-06 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3361255B1 (en) 2013-01-17 2020-03-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP2018518676A (ja) * 2015-06-11 2018-07-12 アスチュート メディカル,インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
CN109073620A (zh) * 2016-02-22 2018-12-21 健康跨度Dx公司 用于预防或降低急性肾损伤的方法
EP3465201A4 (en) 2016-06-06 2020-08-26 Astute Medical, Inc. MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR
US10592554B1 (en) * 2017-04-03 2020-03-17 Massachusetts Mutual Life Insurance Company Systems, devices, and methods for parallelized data structure processing

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Publication number Publication date
EP2394166A1 (en) 2011-12-14
EP2394166B1 (en) 2016-07-13
CA2751435A1 (en) 2010-08-12
HK1167455A1 (zh) 2012-11-30
JP2012517594A (ja) 2012-08-02
CN102439441A (zh) 2012-05-02
EP2394166A4 (en) 2012-09-26
AU2010210540A1 (en) 2011-09-15
WO2010091236A1 (en) 2010-08-12
AU2010210540B2 (en) 2015-06-18
US20120053072A1 (en) 2012-03-01
NZ594771A (en) 2013-06-28
NZ601575A (en) 2014-08-29
WO2010091236A9 (en) 2010-11-18

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