CN102423545A - Ultrasonic crystallizing equipment used in natural product or chemical agent crystallization and purification - Google Patents
Ultrasonic crystallizing equipment used in natural product or chemical agent crystallization and purification Download PDFInfo
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- CN102423545A CN102423545A CN2011103210455A CN201110321045A CN102423545A CN 102423545 A CN102423545 A CN 102423545A CN 2011103210455 A CN2011103210455 A CN 2011103210455A CN 201110321045 A CN201110321045 A CN 201110321045A CN 102423545 A CN102423545 A CN 102423545A
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Abstract
The invention discloses ultrasonic crystallizing equipment used in natural product or chemical agent crystallization and purification. The equipment comprises a crystallization chamber, an ultrasonic transducer, a temperature probe, a turbidity probe, a stirring device and a master controlling system. The crystallization chamber has a sandwich structure. An inlet is arranged on the upper part of the crystallization chamber, and an outlet is arranged on the lower end of the crystallization chamber. The ultrasonic transducer is arranged on the outer wall of a circulation pipeline. The temperature probe and the turbidity probe are arranged in the crystallization chamber, and are used for transmitting electrical signals to the master controlling system. With ultrasound, nucleation is reinforced and excited, and crystal growth speed is improved, such that crystallization period is shortened, and production efficiency is improved. The particle sizes of the crystals are uniformly distributed, such that the product quality is improved. The equipment is time-saving, and is advantaged in high efficiency and high product quality. The entire production process is controllable, and the equipment can be used in industrialized productions.
Description
Technical field
The present invention relates to a kind of equipment that is used for natural products or chemicals crystallization purifying, relate in particular to a kind of ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying.
Background technology
Ultrasonic wave is meant the sound wave of frequency more than 20KHz, and it can not cause people's the sense of hearing, is the communication processes of a kind of mechanical oscillation in medium, has characteristics such as pack, orientation, reflection, transmission.As a kind of physical energy form, ultrasonic wave has been widely used in aspects such as natural product extraction, chemistry and chemical industry, environmental protection, food industry, bioengineering.
The solution crystallization process is that material is the process of crystalline state from liquid transformation, experience two steps: crystallization nucleation and crystal growth.Crystallization nucleation is the nucleus that in supersaturated solution, generates some; And on the basis of nucleus, grow into crystal, then be crystal growth.
Method for crystallising of the prior art mainly improves the production capacity of equipment through introducing crystal seed and raising solution concentration, but the products obtained therefrom particle diameter differs, inferior quality.
Summary of the invention
The purpose of this invention is to provide the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying that a kind of crystallizing cycle is short, crystal particle diameter is evenly distributed, product quality is high.
The objective of the invention is to realize through following technical scheme:
The present invention is used for the ultrasonic crystallizer of natural products or chemicals crystallization purifying, comprises crystallisation chamber, and the top of said crystallisation chamber is provided with import, and outlet is arranged at the bottom, and import links to each other through the circulation line that is provided with circulating pump with outlet;
The outer wall of said circulation line is provided with ultrasonic transducer, is connected with solution inlet port and taphole on the said circulation line, and said solution inlet port is provided with liquid feeding pump;
Said crystallization chamber is provided with temp probe, turbidity probe tip, agitating device;
The wall of said crystallisation chamber is a sandwich, and interlayer is provided with circulating water intake and circulating water outlet.
Technical scheme by the invention described above provides can be found out, the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying provided by the invention is because the import of crystallisation chamber links to each other through the circulation line that is provided with circulating pump with outlet; The outer wall of circulation line is provided with ultrasonic transducer, is connected with solution inlet port and taphole on the circulation line, and solution inlet port is provided with liquid feeding pump; Crystallization chamber is provided with temp probe, turbidity probe tip, mixer; The wall of crystallisation chamber is a sandwich; Interlayer is provided with circulating water intake and circulating water outlet; Utilize ultrasound-enhanced stimulation crystallization nucleation, improve crystalline growth speed, have that crystallizing cycle is short, crystal particle diameter is evenly distributed, but characteristics such as product quality is high, the controlled suitability for industrialized production of whole process.
Description of drawings
The structural representation of the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying that Fig. 1 provides for the embodiment of the invention.
The specific embodiment
To combine accompanying drawing that the embodiment of the invention is done to describe in detail further below.
The ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying of the present invention, its preferable specific embodiment is:
Comprise crystallisation chamber, the top of said crystallisation chamber is provided with import, and outlet is arranged at the bottom, and import links to each other through the circulation line that is provided with circulating pump with outlet;
The outer wall of said circulation line is provided with ultrasonic transducer, is connected with solution inlet port and taphole on the said circulation line, and said solution inlet port is provided with liquid feeding pump;
Said crystallization chamber is provided with temp probe, turbidity probe tip, agitating device;
The wall of said crystallisation chamber is a sandwich, and interlayer is provided with circulating water intake and circulating water outlet;
Said recirculated water is used for the crystallization chamber temperature controlling.
Said agitating device comprises motor, puddler and flabellum.
Also comprise turn-key system, said turn-key system comprises ultrasound control unit, temperature control unit, stirring control module, turbidity display unit, power supply indicating member.
Said ultrasonic transducer is the divergence expression ultrasonic transducer.
The ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying of the present invention utilizes ultrasound-enhanced stimulation crystallization nucleation, improves crystalline growth speed.Have that crystallizing cycle is short, crystal particle diameter is evenly distributed, but characteristics such as product quality is high, the controlled suitability for industrialized production of whole process.
The purpose of this invention is to provide a kind of ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying, it is realized through following technical scheme:
Among the present invention, ultrasonic transducer is positioned on the outer wall of circulation line, and parameters such as its frequency, power are controlled by turn-key system; Temperature and turbidity probe tip are positioned at crystallizing tank, and its signal of telecommunication is passed to turn-key system; Turn-key system is located in the control rack, comprises unit such as ultrasonic control, temperature control, stirring control and turbidity demonstration, power supply indication; The circulating water intake of crystallisation chamber interlayer can freeze to crystal solution or heats with outlet through recirculated water.
Specific embodiment:
As shown in Figure 1, the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying in the present embodiment comprises: crystallisation chamber 1, ultrasonic transducer 2, temp probe 3, turbidity probe tip 4, mixer 5 and control rack 6 are formed.Crystallisation chamber 1 is a sandwich, and import 7 is arranged at top, and there is outlet 8 lower end, and import links to each other through circulating pump 9, loop 10 with outlet; Solution inlet port 11, crystal solution outlet 12 links to each other with the loop through triple valve 13,14 respectively; Also have liquid feeding pump 15 and filter screen 16 between solution inlet port 11 and the triple valve 13.Also be provided with circulating water intake 17 and circulating water outlet 18 on the crystallisation chamber interlayer.
The above; Be merely the preferable specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, any technical staff who is familiar with the present technique field is in the technical scope that the present invention discloses; The variation that can expect easily or replacement all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of claims.
Claims (4)
1. a ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying is characterized in that, comprise crystallisation chamber, the top of said crystallisation chamber is provided with import, and outlet is arranged at the bottom, and import links to each other through the circulation line that is provided with circulating pump with outlet;
The outer wall of said circulation line is provided with ultrasonic transducer, is connected with solution inlet port and taphole on the said circulation line, and said solution inlet port is provided with liquid feeding pump;
Said crystallization chamber is provided with temp probe, turbidity probe tip, agitating device;
The wall of said crystallisation chamber is a sandwich, and interlayer is provided with circulating water intake and circulating water outlet.
2. the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying according to claim 1 is characterized in that said agitating device comprises motor, puddler and flabellum.
3. the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying according to claim 1 and 2; It is characterized in that; Also comprise turn-key system, said turn-key system comprises ultrasound control unit, temperature control unit, stirring control module, turbidity display unit, power supply indicating member.
4. the ultrasonic crystallizer that is used for natural products or chemicals crystallization purifying according to claim 1 and 2 is characterized in that said ultrasonic transducer is the divergence expression ultrasonic transducer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103210455A CN102423545A (en) | 2011-10-21 | 2011-10-21 | Ultrasonic crystallizing equipment used in natural product or chemical agent crystallization and purification |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103210455A CN102423545A (en) | 2011-10-21 | 2011-10-21 | Ultrasonic crystallizing equipment used in natural product or chemical agent crystallization and purification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102423545A true CN102423545A (en) | 2012-04-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103210455A Pending CN102423545A (en) | 2011-10-21 | 2011-10-21 | Ultrasonic crystallizing equipment used in natural product or chemical agent crystallization and purification |
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| CN (1) | CN102423545A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102872612A (en) * | 2012-10-15 | 2013-01-16 | 中国工程物理研究院化工材料研究所 | Ultrasonic crystallizer |
| CN107008028A (en) * | 2017-05-22 | 2017-08-04 | 天津晶润锐拓科技发展有限公司 | A kind of crystallizer by ultrasonic wave control crystallization nucleation process |
| CN110639415A (en) * | 2019-09-30 | 2020-01-03 | 苏州天际创新纳米技术有限公司 | Continuous dispersion system, catalyst batch synthesis device and method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011124515A1 (en) * | 2010-04-08 | 2011-10-13 | Jesalis Pharma Gmbh | Method for producing crystalline active ingredient particles |
| CN202237361U (en) * | 2011-10-21 | 2012-05-30 | 北京弘祥隆生物技术股份有限公司 | Ultrasonic crystallization device used for crystallizing and purifying natural products or chemical drugs |
-
2011
- 2011-10-21 CN CN2011103210455A patent/CN102423545A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011124515A1 (en) * | 2010-04-08 | 2011-10-13 | Jesalis Pharma Gmbh | Method for producing crystalline active ingredient particles |
| CN202237361U (en) * | 2011-10-21 | 2012-05-30 | 北京弘祥隆生物技术股份有限公司 | Ultrasonic crystallization device used for crystallizing and purifying natural products or chemical drugs |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102872612A (en) * | 2012-10-15 | 2013-01-16 | 中国工程物理研究院化工材料研究所 | Ultrasonic crystallizer |
| CN102872612B (en) * | 2012-10-15 | 2013-11-27 | 中国工程物理研究院化工材料研究所 | Ultrasonic crystallizer |
| CN107008028A (en) * | 2017-05-22 | 2017-08-04 | 天津晶润锐拓科技发展有限公司 | A kind of crystallizer by ultrasonic wave control crystallization nucleation process |
| CN107008028B (en) * | 2017-05-22 | 2023-09-08 | 天津晶润锐拓科技发展有限公司 | Crystallizer for controlling crystallization and nucleation process through ultrasonic waves |
| CN110639415A (en) * | 2019-09-30 | 2020-01-03 | 苏州天际创新纳米技术有限公司 | Continuous dispersion system, catalyst batch synthesis device and method |
| WO2021062940A1 (en) * | 2019-09-30 | 2021-04-08 | 青岛创启新能催化科技有限公司 | Continuous dispersion system, catalyst batch synthesis apparatus and method |
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Application publication date: 20120425 |