CN102423388A - Traditional Chinese medicine composition for oral ulcer - Google Patents

Traditional Chinese medicine composition for oral ulcer Download PDF

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Publication number
CN102423388A
CN102423388A CN201110350651XA CN201110350651A CN102423388A CN 102423388 A CN102423388 A CN 102423388A CN 201110350651X A CN201110350651X A CN 201110350651XA CN 201110350651 A CN201110350651 A CN 201110350651A CN 102423388 A CN102423388 A CN 102423388A
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weight portion
parts
weight
chinese medicine
ulcer
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CN201110350651XA
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CN102423388B (en
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顾兰荪
顾振达
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Gu Guiming
Shanghai Pudong New District Beicai Community Health Service Center
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SHANGHAI PUDONG NEW DISTRICT BEICAI COMMUNITY HEALTH SERVICE CENTER
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Abstract

The invention provides a traditional Chinese medicine composition and its purpose. The traditional Chinese medicine composition comprises the following raw materials: 0.5-1.5 parts of baikal skullcap root, preferably 1-1.5 parts of baikal skullcap root; 0.5-1.5 parts of phellodendron bark, preferably 1-1.5 parts of phellodendron bark, 0.6-1.5 parts of hay, preferably 0.6-1 part of hay; 1-7 parts of watermelon frost, preferably 1-1.5 parts of watermelon frost; 0.6-1.5 parts of chalcanthite, preferably 0.6-1 part of chalcanthite; 3-15 parts of borax, preferably 5-15 parts of borax; and 5-10 parts of deer bone cream, preferably 6-7.5 parts of deer bone cream. The traditional Chinese medicine composition has the efficiency of clearing heat, detoxication, removing blood stasis, promoting blood circulation and relieving pain, and is used for treating laryngopathy and oral ulcer.

Description

The Chinese medicine composition of treatment oral ulcer
Technical field
The present invention relates to the field of Chinese medicines.More specifically, the present invention relates to treat laryngopathy and oral ulcer, especially the Chinese medicine composition of recurrent oral ulceration.
Background technology
Recurrent oral ulceration is claimed recurrent aphtha, its stomatitis of Ah not again, is a kind of chronic inflammatory disease of stubbornness, is that oral mucosa takes place little and the ulcer of pain has recurrent.The oral ulcer majority is that being dispersed in property is distributed in easy active mucosa zone, and usually pain makes the difficult peace of patient's sleeping and eating unbearably.Epidemiological study shows that per 5 philtrums promptly have 1 people that ulcer took place 1 time at least, no matter and men and women, age, ethnic group all can take place.Modern medicine thinks that oral ulcer can recovery from illness voluntarily in 7~10 days.Problem is that many patients' the state of an illness tends to repeatedly, and is bad during fashion, thereby influences diet and daily life, makes very much the patient perplex, even sways the emotion.The cause of disease of recurrent oral ulceration and mechanism of causing a disease are still indeterminate.Its inducement possibly be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism possibly play an important role in the generation of recurrent oral ulceration, development.Because etiology unknown, the diagnosis of recurrent oral ulceration is based on medical history and clinical manifestation fully, lacks to can be used as the lab index of making a definite diagnosis foundation.Recurrent oral ulceration is indicating that body has potential systemic disease, and like the disease of gastrointestinal, blood and hormonal system, but most of clinically patient body is healthy, the unsystematic disease.The traditional Chinese medical science is thought the generation of primary disease, and exopathogenic factor is main with pyretic toxicity; Mostly endogenous cause of ill is feelings will internal injury, due to the eating and drinking without temperance, chamber overstrain.In a word, cause that the cause of disease of oral ulcer and pathogenesis are very complicated, thereby can only be based upon on the symptomatology basis the also diagnostic criteria of lack of uniform its diagnosis.Though the modern medicine Drug therapy has certain curative effect, but still exist side effect big, problem such as the scope of application is narrow.Therefore, Chinese and western medicine is still evident in efficacy in continuous trial research and development at present, the scope of application is wider and the less new Aphthasol thing of side effect.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition that can effectively treat laryngopathy and oral ulcer, especially recurrent oral ulceration.This Chinese medicine composition has the effect of heat-clearing and toxic substances removing and detumescence promoting blood circulation and stopping pain.
In first aspect of the present invention, a kind of Chinese medicine composition is provided, said composition comprises following raw material:
Radix Scutellariae 0.5-1.5 weight portion, preferably, the 1-1.5 weight portion;
Cortex Phellodendri 0.5-1.5 weight portion, preferably, the 1-1.5 weight portion;
Radix Glycyrrhizae 0.6-1.5 weight portion, preferably, the 0.6-1 weight portion;
Watermelon crystal 1-7 weight portion, preferably, the 1-1.5 weight portion;
Chalcanthitum 0.6-1.5 weight portion, preferably, the 0.6-1 weight portion;
Borax 3-15 weight portion, preferably, the 5-15 weight portion;
Os Cervi frost 5-10 weight portion, preferably, the 6-7.5 weight portion;
Water chestnut starch 3-15 weight portion, preferably, the 3-5 weight portion;
Du's word Moschus 0.2-0.5 weight portion; With
Hundred longevity Borneolum Syntheticum 1-3 weight portions.
In another aspect of this invention, a kind of Chinese medicine composition of treating oral ulcer is provided, said composition preferably includes following raw material:
Radix Scutellariae 1.2 weight portions;
Cortex Phellodendri 1.2 weight portions;
Radix Glycyrrhizae 0.6 weight portion;
Watermelon crystal 1.2 weight portions;
Chalcanthitum 0.6 weight portion;
Borax 3 weight portions;
Os Cervi frost 6 weight portions;
Water chestnut starch 3 weight portions;
Du's word Moschus 0.2 weight portion; With
Hundred longevity Borneolum Syntheticums, 1 weight portion.
In one side more of the present invention, the purposes of above-mentioned Chinese medicine composition on the medicine of preparation treatment laryngopathy or oral ulcer is provided.Above-mentioned laryngopathy for example includes but not limited to acute/chronic pharyngitis, acute and chronic tonsillitis, laryngopharynx swelling and pain and follicle hypertrophy.Above-mentioned oral ulcer for example includes but not limited to child, adult various aphthas and recurrent oral ulceration.
Preferably, compositions of the present invention can directly be processed powder, applies or blows cloth in oral ulcer zone, perhaps blows in throat.
Compositions of the present invention also can with pharmaceutically acceptable carrier combinations, process conventional dosage form according to the pharmaceutical methods of routine, preferably process solid formulation, for example powder, pill, tablet, Orally-disintegrating tablet etc.
Others of the present invention are because the disclosure of this paper is conspicuous to those skilled in the art.In should be understood that within the scope of the present invention, above-mentioned each technical characterictic of the present invention and hereinafter can mutual combination between specifically described each technical characterictic in (like embodiment), thus constitute new or optimized technical scheme.As space is limited, this tired no longer one by one stating.
The specific embodiment
1, pharmaceutical composition of the present invention---powder
The prescription of described pharmaceutical composition is following:
Radix Scutellariae 6 grams;
Cortex Phellodendri 6 grams;
Radix Glycyrrhizae 3 grams;
Watermelon crystal 6 grams;
Chalcanthitum 3 grams;
Borax 15 grams;
Os Cervi frost 30 grams;
Water chestnut starch 15 grams;
Du's word Moschus 1 gram; With
Hundred longevity Borneolum Syntheticums, 5 grams.
2, preparation of drug combination method of the present invention
Get the raw material of each said weight by above-mentioned prescription, pulverize as described below, be mixed and made into medicated powder.
Borax (being Borax): fry pine, slow fire behind the first intense fire, color Bai Weijia does not contain burned black.
Water chestnut starch: Corm Eleocharitis is removed the peel only in vain after Winter Solstice, and pulping changes clear water several times, and post precipitation takes out and dries into powder.
Watermelon crystal: select 1 of the Citrullus vulgaris of heavily about 3000-3500 gram, cut at the place Pedicellus Melo, flesh in the cutouts; Fill in the melon with Mirabilitum 500 grams, then the melon skin that downcuts is covered, use the bamboo let stickfast; Hang on the shady and cool ventilation part, bloom is promptly constantly separated out in the melon skin outside after January, and continuous the sweeping down of white network got final product.The watermelon crystal that is worth should be deposited the Calx cylinder or be enclosed within the porcelain vase, and is cool to drying place, protection against the tide, solar heat protection.
Chalcanthitum: winter native alum is immersed in the Mylopharyngodon piceus bile and dries in the shade, be placed on then to fry in the pot and grind usefulness thoroughly into powder.
Other raw materials all by routine operation processing, are ground into fine powder.
More than various medicated powder, all choose the article authentic medicinal herbs, according to operating routines such as soaking, fry, forge, grind, water flies, and note seasonal.
The processing of medicated powder of the present invention must be ground into superfinely, reaches the noiseless degree that is, some tongue water, and then filter with the close thin,tough silk of 100-120 hole purpose, if medicated powder is coarse, stimulate easily, cause easypro and pain, affect the treatment.Because of containing the Borneolum Syntheticum aromatic odor in this medicated powder, in the porcelain vase with its storage and sealing, do not make disappointingly, prevent that fragrance runs off, and reduces drug effect.
3, the treatment curative effect of pharmaceutical composition of the present invention
Clinical Practice, medicated powder of the present invention have the effect of heat-clearing and toxic substances removing and detumescence promoting blood circulation and stopping pain, are applicable to all laryngopathys of treatment and oral ulcer.Like laryngopharynx swelling and pain, follicle hypertrophy and recurrent oral ulceration.Above-mentioned medicated powder also can be used with the medicine of other treatment throat diseases or oral ulcer.In outpatient service if when needing matching medication; General blowing in throat with this medicated powder earlier gets final product alleviating pain; Mitigation symptoms to the patient of laryngopharynx swelling and pain, follicle hypertrophy and recurrent oral ulceration, directly contacts focus through medicated powder of the present invention; The patient can feel pharyngeal refrigerant, Gan Run and comfortable, pain relief after half an hour.
Treatment example 1
Patient's soup, the man, 54 years old, symptom showed as during prescription on individual diagnosis: oral mucosa pain, three to five place's ulcer are arranged, the about 10-30mm of diameter, the persistent period, secretions increased more than 1 day, and drinking-water and feed are hindered, and there is burning sensation at the ulcer place, and there are tooth seal, thin white fur of tongue in the tongue limit.Body temperature is normal, and lymph node does not have enlargement.Belong to recurrent oral ulceration after diagnosing.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface fully.Jet 4-5 every day, makes medicated powder stay in ulcer surface 20 minutes at least at every turn.SM to the is in the time of 8 days, and patient's symptom has clear improvement, and is embodied in: the oral mucosa pain weakens, and discomfort is only arranged slightly, and the ulcer number reduces, the about 3-5mm of diameter, and burning sensation disappears.Continue medication to the 28 days, the complete obiteration of patient's above-mentioned symptom, the ulcer surface healing, painless, can normally take food and drink water.
Treatment example 2
Patient Wang, the woman, 35 years old, symptom showed as during prescription on individual diagnosis: the oral mucosa causalgia is obvious, and the above ulcer in five places is arranged, and diameter is little, about 1-3m, the persistent period, secretions increased more than 3 days, and drinking-water and feed are hindered, and there is burning sensation at the ulcer place, and there are tooth seal, thin white fur of tongue in the tongue limit.Body temperature is normal, and lymph node does not have enlargement.Belong to recurrent oral ulceration after diagnosing.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface fully.Jet 4-5 every day, makes medicated powder stay in ulcer surface 20 minutes at least at every turn.SM to the is in the time of 8 days, and patient's symptom makes moderate progress, and is embodied in: the sense of oral mucosa causalgia weakens, and shows as pain, and the ulcer number reduces in 5, but drinking-water and feed are still difficult, and there is burning sensation at the ulcer place.Continue medication to the 15 days, the oral mucosa pain weakens, and shows as discomfort slightly, and the ulcer number reduces in 3.Continue medication to the 28 days, patient's above-mentioned symptom disappears basically, and ulcer surface heals basically, and discomfort is arranged slightly, can normally take food and drink water.
Treatment example 3
Patient Zheng, the man, 40 years old, symptom showed as during prescription on individual diagnosis: oral mucosa pain, three to five place's ulcer are arranged, the about 10-30mm of diameter, the persistent period, secretions increased more than 7 days, and drinking-water and feed are hindered, and there is burning sensation at the ulcer place, and there are tooth seal, thin white fur of tongue in the tongue limit.Body temperature is normal, and lymph node does not have enlargement.Belong to recurrent oral ulceration after diagnosing.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface fully.Jet 4-5 every day, makes medicated powder stay in ulcer surface 20 minutes at least at every turn.SM to the is in the time of 8 days, and patient's symptom makes moderate progress, and is embodied in: the ulcer number reduces, the about 3-5mm of diameter, and burning sensation disappears.Continue medication to 15 day, the oral mucosa pain weakens, and shows as uncomfortable slightly.Continue medication to the 28 days, the complete obiteration of patient's above-mentioned symptom, the ulcer surface healing, painless, can normally take food and drink water.
Treatment example 4
Patient Ma, the woman, 52 years old, symptom showed as during prescription on individual diagnosis: the oral mucosa causalgia is obvious, and the above ulcer in five places is arranged; Diameter is little, about 1-3m, and the persistent period, secretions increased more than 10 days; Drinking-water and feed are hindered, and there is burning sensation at the ulcer place, and there are tooth seal, thin white fur of tongue in the tongue limit.Body temperature is normal, and lymph node does not have enlargement.Belong to recurrent oral ulceration after diagnosing.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface fully.Jet 4-5 every day, makes medicated powder stay in ulcer surface 20 minutes at least at every turn.SM to the is in the time of 8 days, and patient's symptom makes moderate progress, and is embodied in: the sense of oral mucosa causalgia weakens, and shows as pain, and the ulcer number reduces in 5, but drinking-water and feed are still difficult, and there is burning sensation at the ulcer place.Continue medication to the 15 days, the oral mucosa pain weakens, and shows as discomfort slightly, and the ulcer number reduces in 3.Continue medication to the 28 days, patient's above-mentioned symptom disappears basically, and ulcer surface heals basically, and discomfort is arranged slightly, can normally take food and drink water.
All documents in that the present invention mentions are all quoted as a reference in this application, are just quoted such as a reference separately as each piece document.Should be understood that in addition after having read above-mentioned teachings of the present invention, those skilled in the art can do various changes or modification to the present invention, these equivalent form of values fall within the application's appended claims institute restricted portion equally.

Claims (6)

1. a Chinese medicine composition is characterized in that, said composition contains following raw material:
Radix Scutellariae 0.5-1.5 weight portion;
Cortex Phellodendri 0.5-1.5 weight portion;
Radix Glycyrrhizae 0.6-1.5 weight portion;
Watermelon crystal 1-7 weight portion;
Chalcanthitum 0.6-1.5 weight portion;
Borax 3-15 weight portion;
Os Cervi frost 5-10 weight portion;
Water chestnut starch 3-15 weight portion;
Du's word Moschus 0.2-0.5 weight portion; With
Hundred longevity Borneolum Syntheticum 1-3 weight portions.
2. Chinese medicine composition as claimed in claim 1 is characterized in that, said composition contains following raw material:
Radix Scutellariae 1-1.5 weight portion;
Cortex Phellodendri 1-1.5 weight portion;
Radix Glycyrrhizae 0.6-1 weight portion;
Watermelon crystal 1-1.5 weight portion;
Chalcanthitum 0.6-1 weight portion;
Borax 5-15 weight portion;
Os Cervi frost 6-7.5 weight portion;
Water chestnut starch 3-5 weight portion;
Du's word Moschus 0.2-0.5 weight portion; With
Hundred longevity Borneolum Syntheticum 1-3 weight portions.
3. Chinese medicine composition as claimed in claim 1 is characterized in that, said composition contains following raw material:
Radix Scutellariae 1.2 weight portions;
Cortex Phellodendri 1.2 weight portions;
Radix Glycyrrhizae 0.6 weight portion;
Watermelon crystal 1.2 weight portions;
Chalcanthitum 0.6 weight portion;
Borax 3 weight portions;
Os Cervi frost 6 weight portions;
Water chestnut starch 3 weight portions;
Du's word Moschus 0.2 weight portion; With
Hundred longevity Borneolum Syntheticums, 1 weight portion.
4. the said arbitrary compositions of claim 1-3 is used to treat the purposes on the medicine of laryngopathy or oral ulcer in preparation.
5. purposes as claimed in claim 4 is characterized in that said laryngopathy comprises laryngopharynx swelling and pain and follicle hypertrophy.
6. purposes as claimed in claim 4 is characterized in that said oral ulcer comprises recurrent oral ulceration.
CN201110350651.XA 2011-11-08 2011-11-08 Traditional Chinese medicine composition for oral ulcer Active CN102423388B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656328A (en) * 2014-01-08 2014-03-26 关庆玲 Traditional Chinese medicine composition for treating liver and gallbladder damp-heat syndrome recurrent oral ulceration

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279975A (en) * 2000-07-11 2001-01-17 刘文功 Medicine for curing stomatocase
CN1457833A (en) * 2003-04-29 2003-11-26 桂林三金药业股份有限公司 Medicinal composition for curing oral and throa diseases and its preparing method, use and quality control method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279975A (en) * 2000-07-11 2001-01-17 刘文功 Medicine for curing stomatocase
CN1457833A (en) * 2003-04-29 2003-11-26 桂林三金药业股份有限公司 Medicinal composition for curing oral and throa diseases and its preparing method, use and quality control method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
孙世发、左言富主编: "《世界传统医学方剂学》", 31 December 1999 *
朱祥成: "中医喉科吹药的特点及临床应用经验", 《中华中医药学会耳鼻喉科分会第15届学术交流会论文集》 *
李彦华等: "中医喉科吹药法初探", 《新疆中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656328A (en) * 2014-01-08 2014-03-26 关庆玲 Traditional Chinese medicine composition for treating liver and gallbladder damp-heat syndrome recurrent oral ulceration

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Owner name: GU GUIMING

Effective date: 20130903

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Address after: 201204 Shanghai City, Pudong New Area Road No. 271 North Cai Zhen Lian

Applicant after: Shanghai Pudong New District Beicai Community Health Service Center

Applicant after: Gu Guiming

Address before: 201204 Shanghai City, Pudong New Area Road No. 271 North Cai Zhen Lian

Applicant before: Shanghai Pudong New District Beicai Community Health Service Center

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