CN102423391B - Traditional Chinese medicine composition for treating oral ulcer - Google Patents
Traditional Chinese medicine composition for treating oral ulcer Download PDFInfo
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- CN102423391B CN102423391B CN201110350883.5A CN201110350883A CN102423391B CN 102423391 B CN102423391 B CN 102423391B CN 201110350883 A CN201110350883 A CN 201110350883A CN 102423391 B CN102423391 B CN 102423391B
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Abstract
The invention provides a traditional Chinese medicine composition and purpose thereof. Specifically, the composition comprises raw materials of: 5-34 weight parts of calcined plaster, and preferably 8-15 weight parts; 3-15 weight parts of borax, and preferably 5-15 weight parts; 3-15 weight parts of water chestnut powder, and preferably 5-15 weight parts; 3-15 weight parts of shang natural Indigo, and preferably 3-10 weight parts; 2.5-9 weight parts of sediment of human urine, and preferably 3-7 weight parts; and 1-3 weight parts of borneol. The traditional Chinese medicine composition has efficacies of clearing heat, detoxifying, transforming putridity, engendering flesh, subsiding swelling, relieving pain and astringing dampness and astringing sores, and can be used for treating laryngopathy and oral ulcer.
Description
Technical field
The present invention relates to the field of Chinese medicines.More specifically, the present invention relates to treat laryngopathy and oral ulcer, especially the Chinese medicine composition of recurrent oral ulceration.
Background technology
Recurrent oral ulceration, claims again recurrent aphtha, its stomatitis of Ah not, is a kind of chronic inflammatory disease of stubbornness, is that oral mucosa occurs little and the ulcer of pain has recurrent.Oral ulcer majority is the mucosa region that being dispersed in property is distributed in easy activity, and usually hurt like hell, makes the difficult peace of patient's sleeping and eating.Epidemiological study shows to have 1 people that ulcer at least occurred 1 time in every 5 people, no matter and men and women, age, ethnic group all can occur.Modern medicine thinks, oral ulcer can recovery from illness voluntarily in 7～10 days.Problem is that many patients' the state of an illness tends to repeatedly, bad during fashion, thereby affects diet and daily life, makes very much patient perplex, and even sways the emotion.The cause of disease of recurrent oral ulceration and mechanism of causing a disease are still indefinite.Its inducement may be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in the generation of recurrent oral ulceration, development.Due to etiology unknown, the diagnosis of recurrent oral ulceration is based on medical history and clinical manifestation completely, lacks and can be used as the lab index of making a definite diagnosis foundation.Recurrent oral ulceration is indicating that body may have potential systemic disease, and as the disease of gastrointestinal, blood and hormonal system, but most of patient body is healthy clinically, unsystematic disease.The traditional Chinese medical science is thought the generation of primary disease, and exopathogenic factor be take pyretic toxicity as main; Endogenous cause of ill mostly is feelings will internal injury, and eating and drinking without temperance, due to chamber overstrain.In a word, cause that the cause of disease of oral ulcer and pathogenesis are very complicated, thereby can only be based upon on symptomatology basis its diagnosis, also lack unified diagnostic criteria.Though modern medicine Drug therapy has certain curative effect, but still exist side effect large, the problem such as the scope of application is narrow.Therefore, at present Chinese and western medicine still research and development are evident in efficacy, the scope of application is wider and the less new Aphthasol thing of side effect constantly attempting.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition that can effectively treat laryngopathy and oral ulcer, especially recurrent oral ulceration.This Chinese medicine composition has heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation, reducing swelling and alleviating pain, the effect of removing dampness sore.
In a first aspect of the present invention, a kind of Chinese medicine composition is provided, said composition comprises following raw material:
Gypsum Fibrosum Preparatum 5-34 weight portion, preferably, 8-15 weight portion;
Borax 3-15 weight portion, preferably, 5-15 weight portion;
Water chestnut starch 3-15 weight portion, preferably, 5-15 weight portion;
Indigo Naturalis 3-15 weight portion, preferably, 3-10 weight portion;
Calamitas urinae hominis 2.5-9 weight portion, preferably, 3-7 weight portion; With
Borneolum Syntheticum 1-3 weight portion.
In another aspect of this invention, provide a kind of Chinese medicine composition for the treatment of oral ulcer, said composition preferably includes following raw material:
Gypsum Fibrosum Preparatum 10 weight portions;
Borax 10 weight portions;
Water chestnut starch 10 weight portions;
Indigo Naturalis 10 weight portions;
Calamitas urinae hominis's 2.57 weight portions; With
Borneolum Syntheticum 1 weight portion.
In another aspect of this invention, provide a kind of Chinese medicine composition, said composition also comprises: waist Huang, Radix Panacis Quinquefolii and Cinnabaris, wherein, the yellow 0.33-4 weight portion of waist, Radix Panacis Quinquefolii 5-10 weight portion, Cinnabaris 0.6-1 weight portion.
In one side more of the present invention, provide the purposes of above-mentioned Chinese medicine composition on the medicine of preparation treatment laryngopathy or oral ulcer.Above-mentioned laryngopathy and oral ulcer for example include but not limited to acute/chronic pharyngitis, acute and chronic tonsillitis and child, adult various aphthas, recurrent oral ulceration.
Preferably, compositions of the present invention can directly be made powder, and apply or blow cloth in oral ulcer region, or Chui Yu throat.
Compositions of the present invention also can with pharmaceutically acceptable carrier combinations, according to conventional pharmaceutical methods, make conventional dosage form, preferably make solid formulation, such as powder, pill, tablet, Orally-disintegrating tablet etc.
Other side of the present invention, due to disclosure herein, is apparent to those skilled in the art.In should be understood that within the scope of the present invention, above-mentioned each technical characterictic of the present invention and can combining mutually between specifically described each technical characterictic in below (eg embodiment), thus form new or preferred technical scheme.As space is limited, at this, tire out and state no longer one by one.
The specific embodiment
1, pharmaceutical composition of the present invention---powder
The formula of described pharmaceutical composition is as follows:
15 grams of Gypsum Fibrosum Preparatum;
15 grams of boraxs;
15 grams of water chestnut starch;
15 grams of Indigo Naturaliss;
10 grams of calamitas urinae hominises; And
1.5 grams of Borneolum Syntheticums.
2, the preparation method of pharmaceutical composition of the present invention
By above-mentioned formula, get the raw material of weight described in each, pulverize as described below, be mixed and made into medicated powder.
Indigo Naturalis: levigation all wants water to fly 5-6 time, rinses, and dries into powder.
Borax (being Borax): fry pine, slow fire after first intense fire, color Bai Weijia, containing not burned black.
Calamitas urinae hominis: by calamitas urinae hominis's water logging 3 years, change one time water 3 days summer and autumns, winter-spring season is changed water for 1 week one time, removes stench and saline taste, then with charcoal fire, forges ripely, is placed on indoor concrete floor, takes out fire-toxin, pulverization, then go to fly, dry into powder.
Water chestnut starch: after Winter Solstice, only in vain, pulping, changes clear water several times in Corm Eleocharitis peeling, takes out and dries into powder after precipitation.
Other raw materials are operation processing routinely all, levigation.
Various medicated powder, all chooses product authentic medicinal herbs above, according to operating routines such as soaking, fry, forge, grind, water flies, and notes seasonal.
The processing of medicated powder of the present invention, must be ground into superfinely, and reaching noiseless is degree, some tongue water, and then filter with the close thin,tough silk of 100-120 hole object, if medicated powder is coarse, easily stimulate, cause easypro and pain, affect the treatment.Because containing Borneolum Syntheticum aromatic odor in this medicated powder, in the porcelain vase of being preserved and sealing, do not make to lose heart, prevent that fragrance runs off, and reduces drug effect.
3, the treatment curative effect of pharmaceutical composition of the present invention
Clinical Practice, medicated powder of the present invention has heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation, reducing swelling and alleviating pain, the effect of removing dampness sore, is applicable to treat all laryngopathys and oral ulcer.The various aphthas of growing up as acute/chronic pharyngitis, acute and chronic tonsillitis and child, all available it.Be particularly useful for recurrent oral ulceration.Above-mentioned medicated powder also can be used in conjunction with the medicine of other treatment throat diseases or oral ulcer.If while needing matching medication in outpatient service, generally first with medicated powder Chui Yu of the present invention throat, get final product alleviating pain, mitigation symptoms, to acute/chronic pharyngitis, as: the patient of newborn pretty young woman, laryngalgia and oral ulcer, through medicated powder of the present invention, directly contact focus, after half an hour, patient can feel pharyngeal refrigerant, Gan Run and comfortable, pain relief.
treatment example 1
Patient Shen Zhengming, man, 54 years old, when medical, Symptoms was: oral mucosa pain, there are three to five place's ulcer, diameter 10-30mm, the persistent period, more than 1 day secretions increased, and drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue.Body temperature is normal, and lymph node is without enlargement.Belong to after diagnosing recurrent oral ulceration.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface completely.Jet 4-5 every day, at least makes medicated powder stay in ulcer surface 20 minutes at every turn.SM to the is in the time of 8 days, and patient's symptom has clear improvement, and is embodied in: oral mucosa pain weakens, and only slightly uncomfortable, ulcer number reduces, diameter 3-5mm, and burning sensation disappears.Continue medication to the 28 days, patient's above-mentioned symptom disappears completely, and ulcer surface healing is painless, can normally take food and drink water.
treatment example 2
Patient Shi Yuzhen, female, 65 years old, when medical, Symptoms was: oral mucosa causalgia is obvious, has the five above ulcer in place, diameter is little, about 1-3m, and the persistent period, more than 3 days secretions increased, drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue.Body temperature is normal, and lymph node is without enlargement.Belong to after diagnosing recurrent oral ulceration.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface completely.Jet 4-5 every day, at least makes medicated powder stay in ulcer surface 20 minutes at every turn.SM to the is in the time of 8 days, and patient's symptom makes moderate progress, and is embodied in: the sense of oral mucosa causalgia weakens, and shows as pain, and ulcer number reduces in 5, but drinking-water and feed are still difficult, and there is burning sensation at ulcer place.Continue medication to the 15 days, oral mucosa pain weakens, and shows as slightly discomfort, and ulcer number reduces in 3.Continue medication to the 28 days, patient's above-mentioned symptom disappears substantially, and ulcer surface heals substantially, slightly uncomfortable, can normally take food and drink water.
treatment example 3
Patient Zhao Jinfang, female, 52 years old, when medical, Symptoms was: oral mucosa pain, there are three to five place's ulcer, diameter 10-30mm, the persistent period, more than 7 days secretions increased, and drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue.Body temperature is normal, and lymph node is without enlargement.Belong to after diagnosing recurrent oral ulceration.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface completely.Jet 4-5 every day, at least makes medicated powder stay in ulcer surface 20 minutes at every turn.SM to the is in the time of 8 days, and patient's symptom makes moderate progress, and is embodied in: ulcer number reduces, diameter 3-5mm, and burning sensation disappears.Continue medication to 15 day, oral mucosa pain weakens, and shows as slightly uncomfortable.Continue medication to the 28 days, patient's above-mentioned symptom disappears completely, and ulcer surface healing is painless, can normally take food and drink water.
treatment example 4
Patient Chen Guoying, female, 60 years old, when medical, Symptoms was: oral mucosa causalgia is obvious, has the five above ulcer in place, diameter is little, about 1-3m, and the persistent period, more than 10 days secretions increased, drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue.Body temperature is normal, and lymph node is without enlargement.Belong to after diagnosing recurrent oral ulceration.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface completely.Jet 4-5 every day, at least makes medicated powder stay in ulcer surface 20 minutes at every turn.SM to the is in the time of 8 days, and patient's symptom makes moderate progress, and is embodied in: the sense of oral mucosa causalgia weakens, and shows as pain, and ulcer number reduces in 5, but drinking-water and feed are still difficult, and there is burning sensation at ulcer place.Continue medication to the 15 days, oral mucosa pain weakens, and shows as slightly discomfort, and ulcer number reduces in 3.Continue medication to the 28 days, patient's above-mentioned symptom disappears substantially, and ulcer surface heals substantially, slightly uncomfortable, can normally take food and drink water.
All documents of mentioning in the present invention are all quoted as a reference in this application, just as each piece of document, are quoted as a reference separately.In addition should be understood that those skilled in the art can make various changes or modifications the present invention after having read above-mentioned teachings of the present invention, these equivalent form of values fall within the application's appended claims limited range equally.
Claims (7)
1. a Chinese medicine composition that is used for the treatment of laryngopathy or oral ulcer, is characterized in that, said composition contains following raw material:
Gypsum Fibrosum Preparatum 5-34 weight portion;
Borax 3-15 weight portion;
Water chestnut starch 3-15 weight portion;
Indigo Naturalis 3-15 weight portion;
Calamitas urinae hominis 2.5-9 weight portion; With
Borneolum Syntheticum 1-3 weight portion.
2. Chinese medicine composition as claimed in claim 1, is characterized in that, said composition contains following raw material:
Gypsum Fibrosum Preparatum 8-15 weight portion;
Borax 5-15 weight portion;
Water chestnut starch 5-15 weight portion;
Indigo Naturalis 3-10 weight portion;
Calamitas urinae hominis 3-7 weight portion; With
Borneolum Syntheticum 1-3 weight portion.
3. Chinese medicine composition as claimed in claim 1, is characterized in that, said composition contains following raw material:
Gypsum Fibrosum Preparatum 10 weight portions;
Borax 10 weight portions;
Water chestnut starch 10 weight portions;
Indigo Naturalis 10 weight portions;
Calamitas urinae hominis's 2.57 weight portions; With
Borneolum Syntheticum 1 weight portion.
4. the Chinese medicine composition as described in claim 1-3 arbitrary, is characterized in that, said composition also contains following raw material:
The yellow 0.33-4 weight portion of waist;
Radix Panacis Quinquefolii 5-10 weight portion; With
Cinnabaris 0.6-1 weight portion.
5. the purposes of the arbitrary described compositions of claim 1-4 on the medicine for the preparation for the treatment of laryngopathy or oral ulcer.
6. purposes as claimed in claim 5, is characterized in that, described laryngopathy comprises acute/chronic pharyngitis and acute and chronic tonsillitis.
7. purposes as claimed in claim 5, is characterized in that, described oral ulcer comprises recurrent oral ulceration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110350883.5A CN102423391B (en) | 2011-11-08 | 2011-11-08 | Traditional Chinese medicine composition for treating oral ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110350883.5A CN102423391B (en) | 2011-11-08 | 2011-11-08 | Traditional Chinese medicine composition for treating oral ulcer |
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| CN102423391A CN102423391A (en) | 2012-04-25 |
| CN102423391B true CN102423391B (en) | 2014-03-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110350883.5A Active CN102423391B (en) | 2011-11-08 | 2011-11-08 | Traditional Chinese medicine composition for treating oral ulcer |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129598A (en) * | 2007-08-16 | 2008-02-27 | 李鹏 | Medicament for treating chronic pharyngitis |
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- 2011-11-08 CN CN201110350883.5A patent/CN102423391B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129598A (en) * | 2007-08-16 | 2008-02-27 | 李鹏 | Medicament for treating chronic pharyngitis |
Non-Patent Citations (2)
| Title |
|---|
| 喉科外用经验方;马鸿声;《上海中医药杂志》;19820228(第2期);19 * |
| 马鸿声.喉科外用经验方.《上海中医药杂志》.1982,(第2期),19. |
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| CN102423391A (en) | 2012-04-25 |
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Owner name: GU GUIMING Effective date: 20130903 |
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Effective date of registration: 20130903 Address after: 201204 Shanghai City, Pudong New Area Road No. 271 North Cai Zhen Lian Applicant after: Shanghai Pudong New District Beicai Community Health Service Center Applicant after: Gu Guiming Address before: 201204 Shanghai City, Pudong New Area Road No. 271 North Cai Zhen Lian Applicant before: Shanghai Pudong New District Beicai Community Health Service Center |
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