CN102423387B - Chinese medicine composition for treating oral ulcers - Google Patents
Chinese medicine composition for treating oral ulcers Download PDFInfo
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- CN102423387B CN102423387B CN201110350639.9A CN201110350639A CN102423387B CN 102423387 B CN102423387 B CN 102423387B CN 201110350639 A CN201110350639 A CN 201110350639A CN 102423387 B CN102423387 B CN 102423387B
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Abstract
The invention provides a Chinese medicine composition and an application thereof. The composition comprises the following ingredients by weight: 5-34 portions of calcined gypsum, preferred 8-15 portions; 3-15 portions of borax, preferred 5-15 portions; 3-15 portions of water chestnut powder, preferred 5-15 portions; 1-3 portions of pearl powder, preferred 1-2 portions; 0.5-1 portions of bezoar; 0.33-4 portions of realgar, preferred 3-4 portions; 1-7 portions of watermelon frost, preferred 5-7 portions; and 1-3 portions of borneol. The Chinese medicine composition has the effects of clearing heat and detoxicating, removing slough and promoting growth of new tissue regeneration, and benefiting pharynx and easing pain, and can be used for treating laryngopathy and oral ulcers.
Description
Technical field
The present invention relates to the field of Chinese medicines.More specifically, the present invention relates to treat laryngopathy and oral ulcer, especially the Chinese medicine composition of recurrent oral ulceration.
Background technology
Modern medicine thinks, throat is the immune organ that body weight for humans is wanted, and many infectious disease and immune disease all have substantial connection with throat.Pharyngolaryngitis is commonly encountered diseases and frequently-occurring disease clinically, has acute and chronic dividing, and belongs to a part for upper respiratory tract infection.Usually conscious having sore throat of patient when acute attack, so owes profit with stalk, pharyngeal not well, and pronunciation owes to raise, and dry pharynx is thought drink and mostly is very with speech, or has the symptoms such as foreign body in pharynx sense, belongs to the traditional Chinese medical science " sore throat " category.
According to theory of Chinese medical science, swallow the pass into stomach, the door that larynx is lung, the heresy of diseases caused by exogenous pathogenic factor enters lung and easily hinders larynx, and improper diet enters stomach and is vulnerable to pharynx, and throat is that evil poison soaks well the ground of staying for a long time.The pharyngolaryngitis cause of disease is clinical inside and outside point, and exopathogenic factor mostly is the heresy being affected by the cold, the heresy of strongly fragrant heat-transformation of a specified duration or wind heat, and " Wenbing Tiaobian, Detailed Analysis of Epidemic Warm Diseases " said " warm pathogen tend to attack the upper orifices, attacking the lung first ", and throat occupies upper, stands in the breach and experiences pathogenic warmth; Endogenous cause of ill mostly is the plain body deficiency of YIN, have a liking for again that food is pungent decocts stir-fry, stagnation of phlegm-heat, upper bright throat or with the passing of time consume the moon of impairing the lung kidney, cause hyperactivity of deficient fire, consumption of body fluid by heat becomes expectorant, expectorant heat follow through on disturb throat, clean the street failure due to, pathology as Golden Mirror of Medicine opinion sore throat is said: " lost for a long time by kidney yin; flaming up of the ministerial fire, the bright lung gold that disappears, respectful clearly making is not all right ".Chronic pharyngolaryngitis is better with Chinese medicine, chronic pharyngolaryngitis is because a variety of causes causes, mainly to cause that because function is disorderly pyretic toxicity smoulders due to floating throat, treat in the market this disease in, western medicine result is not very good, the symptom that everyone shows due to the pathogenesis difference of chronic pharyngolaryngitis thereby chronic pharyngolaryngitis patient is also different, thereby it is unpractical treating all types of chronic pharyngolaryngitiss with the medicine of same formula.
Recurrent oral ulceration, claims again recurrent aphtha, its stomatitis of Ah not, is a kind of chronic inflammatory disease of stubbornness, is that oral mucosa occurs little and the ulcer of pain has recurrent.Oral ulcer majority is the mucosa region that being dispersed in property is distributed in easy activity, and usually hurt like hell makes the difficult peace of patient's sleeping and eating.Epidemiological study shows have 1 people that ulcer at least occurred 1 time in every 5 people, no matter and men and women, age, ethnic group all can occur.Modern medicine thinks, oral ulcer can recovery from illness voluntarily in 7～10 days.Problem is that many patients' the state of an illness tends to repeatedly, bad when fashion, thereby affects diet and daily life, makes very much patient perplex, and even sways the emotion.The cause of disease of recurrent oral ulceration and mechanism of causing a disease are still indefinite.Its inducement may be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in the generation of recurrent oral ulceration, development.Due to etiology unknown, the diagnosis of recurrent oral ulceration is based on medical history and clinical manifestation completely, lacks and can be used as the lab index of making a definite diagnosis foundation.Recurrent oral ulceration is indicating that body may have potential systemic disease, as the disease of gastrointestinal, blood and hormonal system, but most of patient body health clinically, unsystematic disease.The traditional Chinese medical science is thought the generation of primary disease, and exopathogenic factor is taking pyretic toxicity as main; Endogenous cause of ill mostly is feelings will internal injury, and eating and drinking without temperance, due to chamber overstrain.In a word, cause that the cause of disease of oral ulcer and pathogenesis are very complicated, thereby can only be based upon on symptomatology basis its diagnosis, also lack unified diagnostic criteria.Though modern medicine Drug therapy has certain curative effect, but still exist side effect large, the problem such as the scope of application is narrow.
Therefore, Chinese and western medicine is still constantly attempting researching and developing new treatment oral cavity evident in efficacy, that the scope of application is wider, side effect is less and the medicine of laryngopharyngeal diseases at present.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition that can effectively treat laryngopathy and oral ulcer.This Chinese medicine composition has heat-clearing and toxic substances removing, removes the rotten and lets fresh grow, and effect of relieving sore throat and pain.
In a first aspect of the present invention, a kind of Chinese medicine composition is provided, said composition comprises following raw material:
Gypsum Fibrosum Preparatum 5-34 weight portion, preferably, 8-15 weight portion;
Borax 3-15 weight portion, preferably, 5-15 weight portion;
Water chestnut starch 3-15 weight portion, preferably, 5-15 weight portion;
Margarita powder 1-3 weight portion, preferably, 1-2 weight portion;
Calculus Bovis 0.5-1 weight portion;
The yellow 0.33-4 weight portion of waist; Preferably, 3-4 weight portion;
Watermelon crystal 1-7 weight portion, preferably, 5-7 weight portion; With
Borneolum Syntheticum 1-3 weight portion.
In another aspect of this invention, provide a kind of Chinese medicine composition, said composition preferably includes following raw material:
Gypsum Fibrosum Preparatum 10 weight portions;
Borax 10 weight portions;
Water chestnut starch 7 weight portions;
Margarita powder 1 weight portion;
Calculus Bovis 0.6 weight portion;
Yellow 4 weight portions of waist;
Watermelon crystal 7 weight portions; With
Borneolum Syntheticum 1 weight portion.
In one side more of the present invention, provide the purposes of above-mentioned Chinese medicine composition on the medicine of preparation treatment oral disease.Above-mentioned laryngopathy and oral ulcer for example include but not limited to recurrent oral ulceration, acute and chronic pharyngitis disease, mucous hyperemia and follicle hypertrophy.
Preferably, compositions of the present invention can directly be made powder, applies or blows cloth in oral ulcer region, or blowing in throat.
Compositions of the present invention also can with pharmaceutically acceptable carrier combinations, make conventional dosage form according to conventional pharmaceutical methods, preferably make solid formulation, such as powder, pill, tablet, Orally-disintegrating tablet etc.
Other side of the present invention, due to disclosure herein, is apparent to those skilled in the art.In should be understood that within the scope of the present invention, above-mentioned each technical characterictic of the present invention and can combining mutually between specifically described each technical characterictic in below (eg embodiment), thus form new or preferred technical scheme.As space is limited, tire out and state no longer one by one at this.
Detailed description of the invention
1, pharmaceutical composition of the present invention---powder
The formula of described pharmaceutical composition is as follows:
15 grams of Gypsum Fibrosum Preparatum;
15 grams of boraxs;
10 grams of water chestnut starch;
1.5 grams of Margarita powder;
0.9 gram of Calculus Bovis;
Yellow 6 grams of waist;
10 grams of watermelon crystals; With
1.5 grams of Borneolum Syntheticums.
2, the preparation method of pharmaceutical composition of the present invention
Get the raw material of each described weight by above-mentioned formula, pulverize as described below, be mixed and made into medicated powder.
Gypsum Fibrosum: forge ripely with charcoal fire, take out and be placed on Indoor Dry neat cement plate upper three day, take out fire-toxin and use it.
Watermelon crystal: select 1 of the Citrullus vulgaris of heavily about 3000-3500 gram, cut at Pedicellus Melo place, flesh in cutouts, fill in melon with 500 grams of Mirabilitums, then the melon skin cutting is covered, use bamboo let stickfast, hang on shady and cool ventilation part, after January, bloom is constantly separated out in melon skin outside, sweeps down continuous white network.
Borax (being Borax): fry pine, slow fire after first intense fire, color Bai Weijia, containing not burned black.
Water chestnut starch: after Winter Solstice, only in vain, pulping, changes clear water several times in Corm Eleocharitis peeling, takes out and dries into powder after precipitation.
Other raw materials are operation processing routinely all, levigation.
Various medicated powder above, all chooses product authentic medicinal herbs, according to operating routines such as soaking, fry, forge, grind, water flies, and notes seasonal.
The processing of medicated powder of the present invention, must be ground into superfinely, and reaching noiseless is degree, some tongue water, and then filter with the close thin,tough silk of 100-120 hole object, if medicated powder is coarse, easily stimulate, cause easypro and pain, affect the treatment.Because containing Borneolum Syntheticum aromatic odor in this medicated powder, in the porcelain vase of being preserved and sealing, do not make to lose heart, prevent that fragrance runs off, and reduces drug effect.
3, the treatment curative effect of pharmaceutical composition of the present invention
Clinical Practice, medicated powder of the present invention has heat-clearing and toxic substances removing, removes the rotten and lets fresh grow, and effect of relieving sore throat and pain, is applicable to treat acute and chronic pharyngitis disease, mucous hyperemia, follicle hypertrophy and oral ulcer.Above-mentioned medicated powder also can be used in conjunction with the medicine of other treatment throat diseases or oral ulcer.If need matching medication in outpatient service time, generally first blow in throat and get final product alleviating pain with medicated powder of the present invention, mitigation symptoms, to the patient of oral ulcer, acute/chronic pharyngitis, mucous hyperemia and follicle hypertrophy, directly contact focus through medicated powder of the present invention, after half an hour, patient can feel pharyngeal refrigerant, Gan Run and comfortable, pain relief.
treatment example 1
Patient relies certain, man, and 45 years old, when medical, Symptoms was: laryngopharynx swelling and pain, oral mucosa pain, there are three to five place's ulcer, diameter 10-30mm, the persistent period, more than 1 day secretions increased, drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue.Body temperature is normal, and lymph node is without enlargement.Belong to after diagnosing slight pharyngitis and recurrent oral ulceration.Then medicated powder of the present invention is blown in this patient's ulcer place, cover stain infections face completely, blow in throat simultaneously.Jet 4-5 every day, at least makes medicated powder stay in ulcer surface 20 minutes at every turn.When SM to the 8 days, patient's symptom has clear improvement, and is embodied in: have sore throat and alleviate, oral mucosa pain weakens, and only slightly uncomfortable, ulcer number reduces, diameter 3-5mm, and burning sensation disappears.Continue medication to the 28 days, patient's above-mentioned symptom disappears completely, and ulcer surface healing is painless, can normally take food and drink water.
treatment example 2
Patient Zhang, female, 65 years old, when medical, Symptoms was: oral mucosa causalgia is obvious, has the five above ulcer in place, and diameter is little, about 1-3m, the persistent period, more than 3 days secretions increased, and drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue.Body temperature is normal, and lymph node is without enlargement.Belong to after diagnosing recurrent oral ulceration.Then medicated powder of the present invention is blown in this patient's ulcer place, cover ulcer surface completely.Jet 4-5 every day, at least makes medicated powder stay in ulcer surface 20 minutes at every turn.When SM to the 8 days, patient's symptom makes moderate progress, and is embodied in: the sense of oral mucosa causalgia weakens, and shows as pain, and ulcer number reduces in 5, but still difficulty of drinking-water and feed, there is burning sensation at ulcer place.Continue medication to the 15 days, oral mucosa pain weakens, and shows as slightly discomfort, and ulcer number reduces in 3.Continue medication to the 28 days, patient's above-mentioned symptom disappears substantially, and ulcer surface heals substantially, slightly uncomfortable, can normally take food and drink water.
treatment example 3
Patient Wang, man, 48 years old, when medical, Symptoms was: body temperature 39.3 is spent, and patient is the painful shape of face of acute ill, and pharyngeal hemorrhage obvious, left side tonsil is red and swollen as Semen Persicae, yellow, greasy and thin fur.After diagnosing, betiding bottleneck throat abscess around and belong to laryngalgia, is the common acute disease of larynx section, as medication dissipation not in time, steams rotten one-tenth pus.Then medicated powder of the present invention is blown in this patient throat, medicine is directly had an effect to part, play the effect of clearing heat for detumescence.When SM to the 5 days, patient's symptom makes moderate progress, and swelling is disappeared, and pain disappears.
All documents of mentioning in the present invention are all quoted as a reference in this application, are just quoted separately as a reference as each section of document.In addition should be understood that those skilled in the art can make various changes or modifications the present invention after having read above-mentioned teachings of the present invention, these equivalent form of values fall within the application's appended claims limited range equally.
Claims (6)
1. a Chinese medicine composition that can be used for treating oral ulcer, is characterized in that, said composition is made up of following raw material:
Gypsum Fibrosum Preparatum 5-34 weight portion;
Borax 3-15 weight portion;
Water chestnut starch 3-15 weight portion;
Margarita powder 1-3 weight portion;
Calculus Bovis 0.5-1 weight portion;
The yellow 0.33-4 weight portion of waist;
Watermelon crystal 1-7 weight portion; With
Borneolum Syntheticum 1-3 weight portion,
Wherein, the method for making of Gypsum Fibrosum Preparatum, watermelon crystal, borax, water chestnut starch is as follows:
Gypsum Fibrosum Preparatum: forge ripely with charcoal fire, take out and be placed on Indoor Dry neat cement plate upper three day, take out fire-toxin with it;
Watermelon crystal: select 1 of the Citrullus vulgaris of heavy 3000-3500 gram, cut at Pedicellus Melo place, flesh in cutouts, fill in melon with 500 grams of Mirabilitums, then the melon skin cutting is covered, use bamboo let stickfast, hang on shady and cool ventilation part, after January, bloom is constantly separated out in melon skin outside, sweeps down continuous white network;
Borax: fry pine, slow fire after first intense fire, color Bai Weijia, containing not burned black;
Water chestnut starch: after Winter Solstice, only in vain, pulping, changes clear water several times in Corm Eleocharitis peeling, takes out and dries into powder after precipitation.
2. Chinese medicine composition as claimed in claim 1, is characterized in that, said composition is made up of following raw material:
Gypsum Fibrosum Preparatum 8-15 weight portion;
Borax 5-15 weight portion;
Water chestnut starch 5-15 weight portion;
Margarita powder 1-2 weight portion;
Calculus Bovis 0.5-1 weight portion;
The yellow 3-4 weight portion of waist;
Watermelon crystal 5-7 weight portion; With
Borneolum Syntheticum 1-3 weight portion.
3. Chinese medicine composition as claimed in claim 1, is characterized in that, said composition is made up of following raw material:
Gypsum Fibrosum Preparatum 10 weight portions;
Borax 10 weight portions;
Water chestnut starch 7 weight portions;
Margarita powder 1 weight portion;
Calculus Bovis 0.6 weight portion;
Yellow 4 weight portions of waist;
Watermelon crystal 7 weight portions; With
Borneolum Syntheticum 1 weight portion.
4. the purposes of the arbitrary compositions described in claim 1-3 on the medicine for the preparation for the treatment of laryngopathy or oral ulcer, wherein said laryngopathy is acute and chronic pharyngitis disease and follicle hypertrophy.
5. purposes as claimed in claim 4, is characterized in that, described laryngopathy is follicle hypertrophy.
6. purposes as claimed in claim 4, is characterized in that, described oral ulcer is recurrent oral ulceration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110350639.9A CN102423387B (en) | 2011-11-08 | 2011-11-08 | Chinese medicine composition for treating oral ulcers |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110350639.9A CN102423387B (en) | 2011-11-08 | 2011-11-08 | Chinese medicine composition for treating oral ulcers |
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| Publication Number | Publication Date |
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| CN102423387A CN102423387A (en) | 2012-04-25 |
| CN102423387B true CN102423387B (en) | 2014-12-10 |
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| CN201110350639.9A Active CN102423387B (en) | 2011-11-08 | 2011-11-08 | Chinese medicine composition for treating oral ulcers |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102813900B (en) * | 2012-08-21 | 2013-11-13 | 蒋鲁生 | External medicine for treating foot corns |
| CN105412201A (en) * | 2015-12-22 | 2016-03-23 | 南昌理工学院 | Traditional Chinese medicine composition for treating dental ulcer |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579428A (en) * | 2008-05-14 | 2009-11-18 | 北京和润创新医药科技发展有限公司 | Zhuhuang Chuihou preparation and preparation technology thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579428A (en) * | 2008-05-14 | 2009-11-18 | 北京和润创新医药科技发展有限公司 | Zhuhuang Chuihou preparation and preparation technology thereof |
Non-Patent Citations (2)
| Title |
|---|
| 《喉科外用经验方》;马鸿声等;《上海中医药杂志》;19821231(第2期);19 * |
| 马鸿声等.《喉科外用经验方》.《上海中医药杂志》.1982,(第2期),19. * |
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