CN102416158B - 一种预防或治疗十二指肠溃疡的药物组合物 - Google Patents
一种预防或治疗十二指肠溃疡的药物组合物 Download PDFInfo
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- CN102416158B CN102416158B CN 201110413874 CN201110413874A CN102416158B CN 102416158 B CN102416158 B CN 102416158B CN 201110413874 CN201110413874 CN 201110413874 CN 201110413874 A CN201110413874 A CN 201110413874A CN 102416158 B CN102416158 B CN 102416158B
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- Medicines Containing Plant Substances (AREA)
Abstract
Description
组别 | 灌胃物及剂量 |
模型对照组 | 等体积质量分数为0.5%的羧甲基纤维素钠溶液 |
阳性组 | 1.5g/kg/d胃苏颗粒 |
试验组 | 8ml/kg/d本发明实施例1制备的中药口服液 |
组别 | 样本量 | 溃疡指数(mm2) | 溃疡抑制率(%) |
模型对照组 | 15 | 16.82±0.66 | - |
阳性组 | 15 | 7.85±0.53** | 53.4 |
试验组 | 15 | 6.84±0.71**$ | 59.3 |
组别 | 样本量 | PGE2 含量(OD值) | 胃液pH |
模型对照组 | 15 | 0.317±0.021 | 1.52±0.25 |
阳性组 | 15 | 0.375±0.035* | 1.70±0.28 |
试验组 | 15 | 0.386±0.033** | 1.82±0.18* |
Claims (3)
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CN 201110413874 CN102416158B (zh) | 2011-12-10 | 2011-12-10 | 一种预防或治疗十二指肠溃疡的药物组合物 |
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CN102416158A CN102416158A (zh) | 2012-04-18 |
CN102416158B true CN102416158B (zh) | 2013-04-03 |
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CN 201110413874 Active CN102416158B (zh) | 2011-12-10 | 2011-12-10 | 一种预防或治疗十二指肠溃疡的药物组合物 |
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Families Citing this family (1)
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CN105056196B (zh) * | 2015-09-02 | 2019-03-08 | 河南百年康鑫药业有限公司 | 一种治疗消化性溃疡的药物组合物及其制备方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101129692A (zh) * | 2007-08-27 | 2008-02-27 | 尹克华 | 治疗中气虚寒型胃痛的中药 |
CN101185747A (zh) * | 2007-10-17 | 2008-05-28 | 门连社 | 一种治疗肝病的方剂 |
CN101766774B (zh) * | 2010-04-07 | 2011-06-15 | 泰一和浦(北京)中医药研究院有限公司 | 一种治疗十二指肠溃疡的中药组合物及其制备方法 |
CN102205107B (zh) * | 2011-05-27 | 2012-08-08 | 李佃场 | 一种治疗十二指肠溃疡的中药制剂及其制备方法 |
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101129692A (zh) * | 2007-08-27 | 2008-02-27 | 尹克华 | 治疗中气虚寒型胃痛的中药 |
CN101185747A (zh) * | 2007-10-17 | 2008-05-28 | 门连社 | 一种治疗肝病的方剂 |
CN101766774B (zh) * | 2010-04-07 | 2011-06-15 | 泰一和浦(北京)中医药研究院有限公司 | 一种治疗十二指肠溃疡的中药组合物及其制备方法 |
CN102205107B (zh) * | 2011-05-27 | 2012-08-08 | 李佃场 | 一种治疗十二指肠溃疡的中药制剂及其制备方法 |
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Effective date of registration: 20130926 Address after: 226000 West Road, high tech Industrial Development Zone, Jiangsu, Nantong Patentee after: Nantong hi tech Zone Science and Technology City Investment Development Co.,Ltd. Address before: 276017 A302 building, Linyi hi tech Industrial Development Zone, Shandong, China Patentee before: Xu Congyu |
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Effective date of registration: 20170412 Address after: 226300 Nantong high tech Zone, Jiangsu province Jinqiao West Road, No. 8, No. Patentee after: JIANGSU ZODIAC PHARMACEUTICAL CO.,LTD. Address before: 226000 West Road, high tech Industrial Development Zone, Jiangsu, Nantong Patentee before: Nantong hi tech Zone Science and Technology City Investment Development Co.,Ltd. |
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Denomination of invention: The invention relates to a pharmaceutical composition for preventing or treating duodenal ulcer Effective date of registration: 20201216 Granted publication date: 20130403 Pledgee: Nantong Jiangsu rural commercial bank Limited by Share Ltd. Pledgor: JIANGSU ZODIAC PHARMACEUTICAL Co.,Ltd. Registration number: Y2020980009463 |
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Date of cancellation: 20211118 Granted publication date: 20130403 Pledgee: Nantong Jiangsu rural commercial bank Limited by Share Ltd. Pledgor: JIANGSU ZODIAC PHARMACEUTICAL CO.,LTD. Registration number: Y2020980009463 |
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Denomination of invention: Pharmaceutical composition for preventing or treating duodenal ulcer Effective date of registration: 20211119 Granted publication date: 20130403 Pledgee: Nantong Jiangsu rural commercial bank Limited by Share Ltd. Pledgor: JIANGSU ZODIAC PHARMACEUTICAL CO.,LTD. Registration number: Y2021980012846 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20221114 Granted publication date: 20130403 Pledgee: Nantong Jiangsu rural commercial bank Limited by Share Ltd. Pledgor: JIANGSU ZODIAC PHARMACEUTICAL CO.,LTD. Registration number: Y2021980012846 |