CN102415969A - Dandruff-removing and itching-relieving Chinese medicinal composition and use thereof - Google Patents
Dandruff-removing and itching-relieving Chinese medicinal composition and use thereof Download PDFInfo
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Abstract
The invention discloses a dandruff-removing and itching-relieving Chinese medicinal composition, which is prepared by the following steps: preparing a first Chinese medicinal composition by mixing a first red paeony root extract (0.02 to 0.2g/ml), a first cocklebur fruit extract (0.02 to 0.2g/ml) and a semen sesami nigrum extract (0.02 to 0.2g/ml) in a ratio of (1-5):(1-5):1; preparing a second Chinese medicinal composition by mixing a second red paeony root extract (0.02 to 0.2g/ml), a second cocklebur fruit extract (0.02 to 0.2g/ml) and a folium artemisiae argyi extract (0.02 to 0.2g/ml) in a ratio of (1-5):(1-5):1; and mixing the first Chinese medicinal composition and the second Chinese medicinal composition according to a ratio of 1:10 to 10:1, and thus obtaining the dandruff-removing and itching-relieving Chinese medicinal composition. The composition can be used in various hair-care products and has bactericidal, bacteriostatic, dandruff-removing and itching-relieving effects.
Description
Technical field
The invention belongs to fine chemistry industry Chinese medicine daily use chemicals technical field, particularly a kind of to dandruff-removing itching-relieve Chinese medicine composition with dandruff crowd development and uses thereof.
Background technology
Statistics according to hygiene department; The adult of China nearly 60% receives " dandruff problem " puzzlement to some extent; Wherein have people's symptom of 15% very serious, modern study shows, causes that the too much main cause of dandruff is a pityrosporum furfur; The pityrosporum furfur that has some on the scalp of normal healthy people will cause hair problems such as dandruff, head pruritus even seborrheic alopecia when its quantity obviously increases.
The too much crowd's custom of dandruff depends on anti-dandruff shampoo water and removes dandruff.And what use in most of common anti-dandruff shampoo articles for use at present is the antimycotic chemotherapeutic drug mostly anti-dandruff dose, like pyridine sulfidion copper zinc, sulfide, climbazole etc.Though this type can be removed dandruff for anti-dandruff dose, life-time service can produce injury to scalp.And existing clinical treatment not thorough, the state of an illness is shown effect repeatedly, not only can not nourish scalp, can decompose on the contrary to peel off those dryings, loose skin, the situation aggravation that the dandruff is come off.
Summary of the invention
The purpose of the embodiment of the invention is the defective to above-mentioned existing anti-dandruff technology, and a kind of natural and safe, gentle non-stimulated, anti-dandruff effective dandruff-removing itching-relieve Chinese medicine composition are provided.
Another object of the present invention provides the purposes of above-mentioned dandruff-removing itching-relieve Chinese medicine composition.
The technical scheme taked of the present invention is to achieve these goals: a kind of dandruff-removing itching-relieve Chinese medicine composition, to form by first Chinese medicine composition and second Chinese medicine composition, and the proportioning ratio of said first Chinese medicine composition and second Chinese medicine composition is 1～5: 1;
Said first Chinese medicine composition is mixed by first Radix Paeoniae Rubra extract, first Fructus Xanthii extract and Semen Sesami Nigrum extract:
The proportioning ratio of said first Radix Paeoniae Rubra extract, first Fructus Xanthii extract and Semen Sesami Nigrum extract is: 1～5: 1～5: 1;
Said second Chinese medicine composition mixes by stating second Radix Paeoniae Rubra extract, second Fructus Xanthii extract and Folium Artemisiae Argyi extract:
The proportioning ratio of second Radix Paeoniae Rubra extract, second Fructus Xanthii extract and Folium Artemisiae Argyi extract is: 1～5: 1～5: 1.
The concentration of said first Radix Paeoniae Rubra extract, first Fructus Xanthii extract, Semen Sesami Nigrum extract, second Radix Paeoniae Rubra extract and second Fructus Xanthii extract is for being 0.02～0.2g/ml; The concentration of said Folium Artemisiae Argyi extract is for being 0.01～0.2g/ml.
The concentration of said first Radix Paeoniae Rubra extract, first Fructus Xanthii extract, Semen Sesami Nigrum extract, second Radix Paeoniae Rubra extract and second Fructus Xanthii extract is for being 0.06～0.12g/ml; The concentration of said Folium Artemisiae Argyi extract is for being 0.01～0.12g/ml.
The extraction solvent of said extract is purified water or ethanol, and said proportioning ratio is volume ratio or weight ratio.
Said first Radix Paeoniae Rubra extract is a Radix Paeoniae Rubra microwave extraction thing; Said second Radix Paeoniae Rubra extract is a Radix Paeoniae Rubra ultrasonic extraction thing; Said first Fructus Xanthii extract is a Fructus Xanthii microwave extraction thing; Said second Fructus Xanthii extract is the Fructus Xanthii sonicated extract; Said Semen Sesami Nigrum extract is a Semen Sesami Nigrum microwave extraction thing; Said Folium Artemisiae Argyi extract is a Folium Artemisiae Argyi ultrasonic extraction thing.
The embodiment of the invention also provides a kind of dandruff-removing itching-relieve Chinese medicine composition to be used to wash the purposes of hair products.
The said hair products of washing are selected from shampoo, hair conditioner, send out a kind of in film, gel water, the elastin.
Each Chinese medicine medicinal function of the present invention is:
Radix Paeoniae Rubra: the detumescence of stasis-dispelling and pain-killing, removing heat from blood, have invigorate blood circulation, antiinflammatory, antibiotic, the expansion blood capillary quickens the skin blood microcirculation, eliminates effects such as local inflammation.
Fructus Xanthii: expelling wind and removing dampness, wind-repellent itching-relieving, anti-inflammation, staphylococcus aureus is had stronger inhibitory action, and antifungic action is arranged, can be used for control a skin ulcer, allergic eczema and tinea disease etc.
Semen Sesami Nigrum: invigorating the liver and kidney, blood enriching and dryness moistening, be used to treat early whitening of beard and hair, alopecia etc., have good antiinflammatory action, can promote the recovery of inflammation.
Folium Artemisiae Argyi: removing dampness by means of aromatics, promoting blood circulation and stopping pain, external have good inhibitory effect to all kinds of gram positive bacterias, dermatophytes etc., is usually used in treating skin pruritus.
The beneficial effect of the embodiment of the invention is: dandruff-removing itching-relieve Chinese medicine composition of the present invention, have good inhibitory effect to causing the too much main pathogenic bacterium Malassezia furfur of the dandruff, have simultaneously dispel the wind, invigorate blood circulation, effect such as antipruritic; All medicines share the ailment said due to cold or exposure of removing scalp, damp and hot and antipruritic; Finally play the effect of bactericidal, removing scurf and relieving itching, and promote to increase scalp nutrition by the scalp blood circulation; Strengthen skin metabolism, improve hair quality.Have natural and safe, gentle non-stimulated, anti-dandruff effective advantage.
Further specify effect of the present invention below in conjunction with test:
1. experiment purpose
The factor that causes dandruff formation is more, and one of them principal element is antibacterial and fungal infection, and like staphylococcus, Candida, Pityrosporum etc., special and Malassezia furfur has substantial connection.The effect of the external anti-staphylococcus aureus of this laboratory observation dandruff-removing itching-relieve Chinese medicine composition, escherichia coli, Candida albicans and Malassezia furfur.
2. instrument and material
2.1 instrument
The CW-2000 type is ultrasonic-microwave synergistic extraction appearance (Shanghai Xintuo Microwave Instruments Co., Ltd.); RE-52A type Rotary Evaporators (the inferior flourish instrument and equipment company limited in Shanghai); HH-2K4 type two row four holes intelligence water-bath (Yuhua Instrument Co., Ltd., Gongyi City); The single two-sided clean work station of SW-CJ-1F type (Purifying Equipment Co., Ltd., Suzhou); The biochemical incubator of 8HP-080 type antibacterial (going up the grand experimental facilities company limited of Nereid); YXQ-LS-50S11 type high-pressure sterilizing pot (Medical Equipment Plant of Shanghai Boxun Industrial Co., Ltd.); FA-2004 type electronic balance (the beautiful permanent flat scientific and technological Instr Ltd. of Shanghai Shun).
2.2 reagent
Nutrient agar (Huankai Microbes Tech Co., Ltd., Guangdong, lot number: 201105261).
2.3 strains tested
Candida albicans (ATCC10231), ETEC (ATCC25922), staphylococcus aureus (ATCC6538) and Malassezia furfur (ATCC10231) are provided by the Guangdong Microbes Inst.
2.4 reagent
Semen Sesami Nigrum, Radix Paeoniae Rubra, Fructus Xanthii, Folium Artemisiae Argyi are all purchased the Medicines and Health Product import company limited in Guangdong Province.
3 experimental techniques and result
3.1 the method for preparing of Chinese medicine extract
(1) first Radix Paeoniae Rubra extract: take by weighing the Radix Paeoniae Rubra coarse powder, add at 1: 8 according to solid-liquid ratio and extract aqueous solvent, microwave power is set at 150W; Extraction time 20min; Filtered while hot is concentrated into 0.08g/ml with Rotary Evaporators with filtrate filtered under 70 ℃ of conditions, promptly get Radix Paeoniae Rubra microwave extraction thing.
(2) second Radix Paeoniae Rubra extracts: take by weighing the Radix Paeoniae Rubra coarse powder; Add the extraction aqueous solvent at 1: 10 according to solid-liquid ratio; Ultrasonic power is constant to be 70W, and extraction time is 20min, filtered while hot; Filtrate filtered is concentrated into 0.02g/ml with Rotary Evaporators under 70 ℃ of conditions, promptly gets Radix Paeoniae Rubra ultrasonic extraction thing.
(3) first Fructus Xanthii extracts: take by weighing the Fructus Xanthii coarse powder; Add the extraction aqueous solvent at 1: 12 according to solid-liquid ratio; Microwave power is set at 100W, extraction time 30min, filtered while hot; Filtrate filtered is concentrated into 0.08g/ml with Rotary Evaporators under 70 ℃ of conditions, promptly gets Fructus Xanthii microwave extraction thing.
(4) second Fructus Xanthii extracts: take by weighing the Fructus Xanthii coarse powder; Add the extraction aqueous solvent at 1: 12 according to solid-liquid ratio; Ultrasonic power is constant to be 70W, and extraction time is 30min, filtered while hot; Filtrate filtered is concentrated into 0.08g/ml with Rotary Evaporators under 70 ℃ of conditions, promptly gets Fructus Xanthii ultrasonic extraction thing.
(5) Semen Sesami Nigrum extract: take by weighing the Semen Sesami Nigrum coarse powder, add at 1: 12 according to solid-liquid ratio and extract aqueous solvent, microwave power is set at 150W; Extraction time 20min; Filtered while hot is concentrated into 0.08g/ml with Rotary Evaporators with filtrate filtered under 70 ℃ of conditions, promptly get Semen Sesami Nigrum microwave extraction thing.
(6) Folium Artemisiae Argyi extract: take by weighing the Folium Artemisiae Argyi coarse powder, add at 1: 8 according to solid-liquid ratio and extract aqueous solvent, ultrasonic power is constant to be 50W; Extraction time is 20min; Filtered while hot is concentrated into 0.03g/ml with Rotary Evaporators with filtrate filtered under 70 ℃ of conditions, promptly get Folium Artemisiae Argyi ultrasonic extraction thing.
3.3 the method for preparing of dandruff-removing itching-relieve Chinese medicine composition
Concentration is the Radix Paeoniae Rubra microwave extraction thing of 0.08g/ml, the Fructus Xanthii microwave extraction thing of 0.08g/ml, the Semen Sesami Nigrum microwave extraction thing of 0.08g/ml, is mixed with the microwave compositions according to 1: 1: 1 ratio; Concentration is Radix Paeoniae Rubra sonicated extract, the 0.08g/ml Fructus Xanthii sonicated extract of 0.02g/ml, the Folium Artemisiae Argyi sonicated extract of 0.03g/ml, is mixed with the ultrasound wave compositions according to 1: 1: 1 ratio of volume ratio; Microwave compositions and ultrasound wave compositions are allocated according to 2: 1 proportioning ratio of volume ratio, promptly obtain the dandruff-removing itching-relieve Chinese medicine composition.
3.4 the preparation of bacterium liquid
The bacterium liquid of Candida albicans (ATCC10231), ETEC (ATCC25922), staphylococcus aureus (ATCC6538) and Malassezia furfur (ATCC10231) is respectively according to following method preparation:
On the good nutrient agar panel of sterilization, place 36 ℃ ± 1 ℃ calorstat to cultivate 24h inoculation, above-mentioned bacterial strains is transferred in the good Nutrient agar test tube slant of sterilization with inoculating loop; Place 36 ℃ ± 1 ℃ calorstat to cultivate 24h; In the strain test tube slant that recovery is accomplished, add the physiological saline solution concussion evenly again, be made into bacteria suspension, when to be tested; The 0.1ml bacteria suspension is added in the 4.9ml sterilized water, and processing concentration is 1 * 10
6Cfu/ml～9 * 10
6The bacteria suspension diluent of cfu/ml, subsequent use.
3.5 dandruff-removing itching-relieve Chinese medicine composition bacteriostatic experiment
The dull and stereotyped nutrient agar of plate streaking punch method: 12ml/, a platinum ear polyp liquid intersects rules, and uses the aseptic circular card punch punching of diameter as 5mm, and the dandruff-removing itching-relieve Chinese medicine composition is added in the hand-hole, till filling it up with, must not overflow; Matched group does not add medicine, adds sterilized water, puts respectively in 25 ℃ of calorstats and cultivates 16h～18h, takes out and observes, and with the diameter of kind of calliper inhibition zone, measuring its diameter should be the boundary with the antibacterial ring outer that integral asepsis is born long.
Table 1 dandruff-removing itching-relieve Chinese medicine composition bacteriostatic experiment
Annotate: antibacterial circle diameter is the average antibacterial circle diameter of 3 groups of parallel laboratory tests of Sucus Zingberis.
Antibiotics bacteriostatic experiment result's criterion is: antibacterial circle diameter＞15mm is for the most responsive, and 10～15mm is a medium sensitivity, and 7～9mm is low responsive, does not have antibacterial person for insensitive.Result by table 1 can find out that the dandruff-removing itching-relieve Chinese medicine composition is to staphylococcus aureus, escherichia coli, Candida albicans, Malassezia furfur good antimicrobial effect, and antibacterial circle diameter belongs to the most responsive all greater than 15mm.
3.6 the mensuration of dandruff-removing itching-relieve Chinese medicine composition MIC (Minimal Inhibitory Concentration, minimum inhibitory concentration)
Get 5ml dandruff-removing itching-relieve Chinese medicine composition with the sterile working, put into 45ml Plondrel acid buffer (PBS, the 0.03mol/L phosphate buffer, pH7.2) in, fully concussion dissolving is made into 10% homodisperse solution.Above-mentioned solution reuse PBS (pH7.2) do a times serial dilution, finally is mixed with the test solution that receives of variable concentrations, and it is subsequent use to put 45 ℃～50 ℃ constant temperature water baths by the 0.03mol/L phosphate buffer.Take by weighing 76g MH (caseinhydrolysate agar culture medium) agar culture medium, be dissolved in the 1000ml water, being heated to boiling dissolving, 121 ℃ of pressuresteam sterilization 15min, it is subsequent use to put 45 ℃～50 ℃ water-baths.The sample solution of getting the 10ml serial dilution respectively adds in the plate.Double MH agar culture medium 10ml that will be in 45 ℃～50 ℃ water-baths adds in the plate, and the limit edged rocks flat board, makes the abundant mixing of sample solution and culture medium, waits to solidify afterwards subsequent use.Get with sample injector that 1 μ l～(bacteria containing amount is about 10 to 2 μ l
7Cfu/ml) the bacteria suspension dibbling is in the plate that contains the sample solution culture medium, and (each some bacterium amount is about 10 to the about 5mm～8mm of the inoculation formed bacterium liquid loop diameter in back
4Cfu).Inoculation does not in kind contain the MH agar plate of antipathogenic composition, as positive control.With postvaccinal dull and stereotyped the placement in 35 ℃ of incubators, observed result behind inversion cultivation 18～24h.Pass judgment on regulation: colony growth by the minimum antibacterial liquid concentration that suppresses fully for this sample to being tried the MIC of bacterium, single colony growth can be ignored.
The mensuration of table 2 dandruff-removing itching-relieve Chinese medicine composition MIC
Annotate: "+" expression has bacteria growing; "-" expression asepsis growth
Table 2 result shows that the dandruff-removing itching-relieve Chinese medicine composition has certain inhibitory action to the scalp antibacterial, and when concentration during at 15mg/ml, the growth of staphylococcus aureus, Malassezia furfur is suppressed fully, the aseptic length of being born in the culture dish; Concentration is when 7.5mg/ml, and the growth of ETEC, Candida albicans is suppressed fully, the aseptic length of being born in the culture dish.
4. conclusion
Dandruff-removing itching-relieve Chinese medicine composition of the present invention has the effect of stronger anti-staphylococcus aureus, escherichia coli, Candida albicans and Malassezia furfur.
The result of use of the embodiment of the invention:
1. Mrs Lu 33 years old, owing to often work out of doors, has a large amount of dandruffs to be lamellar in small, broken bits; Pruritus is serious, uses the anti-dandruff shampoo water that adds Chinese medicine composition of the present invention and sends out film after three months, no any discomfort; The dandruff amount reduces, and pruritus alleviates, and the dandruff situation makes moderate progress.
2. Ms Zhang, 23 years old, scalp was fuel-displaced easily; Dandruff is more to be prone to become scattered about on the shoulders, and must wash hair every day, otherwise scalp itch unbearably; Glossy like mirror, the anti-dandruff shampoo water of use interpolation Chinese medicine composition of the present invention and hair conditioner are after three months, and scalp plays the bits amount obviously to be reduced; Improve scalp itch preferably, fuel-displaced a lot of scalp improves gradually originally.
3. Mr. Huang, 30 years old, dandruff was more; Be canescence, hold in hand easily and drop, scratchiness is more obvious; Must wash hair every day keeps the scalp environment clean, use the anti-dandruff shampoo water that adds Chinese medicine composition of the present invention and send out film after three months, the scalp itch sense be improved significantly; Dandruff reduces, and does not have any discomfort.
4. Mrs Han, the woman, 24 years old, use the elastin that adds Chinese medicine composition of the present invention during three months, the sensation scalp is salubrious, and as snug as a bug in a rug, finding then has the effect that improves dandruff, has reduced the number of times of hair washing.
The specific embodiment
Following specific embodiment is described further the present invention, but not as to qualification of the present invention.
Embodiment 1
1, the preparation of Chinese medicine extract:
(1) first Radix Paeoniae Rubra extract: get the Radix Paeoniae Rubra medicinal material coarse powder, add 8 times of water gagings, soak 30min in 80 ℃ of insulations, microwave extraction 20min under the 150W power filters, and it is 0.08g/ml that filtrating is diluted to crude drug content, promptly gets Radix Paeoniae Rubra microwave extraction thing.
(2) second Radix Paeoniae Rubra extracts: get the Radix Paeoniae Rubra medicinal material coarse powder, add 10 times of water gagings, soak 30min in 80 ℃ of insulations, supersound extraction 20min under the 70W power filters, and it is 0.02g/ml that filtrating is diluted to crude drug content, promptly gets Radix Paeoniae Rubra ultrasonic extraction thing.
(3) first Fructus Xanthii extracts: get the Fructus Xanthii medicinal material coarse powder, add 12 times of water gagings, soak 30min in 80 ℃ of insulations, microwave extraction 30min under the 100W power filters, and it is 0.08g/ml that filtrating is diluted to crude drug content, promptly gets Fructus Xanthii microwave extraction thing.
(4) second Fructus Xanthii extracts: get the Fructus Xanthii medicinal material coarse powder, add 12 times of water gagings, soak 30min in 80 ℃ of insulations, supersound extraction 30min under the 70W power filters, and it is 0.08g/ml that filtrating is diluted to crude drug content, promptly gets Fructus Xanthii ultrasonic extraction thing.
(5) Semen Sesami Nigrum extract: get the Semen Sesami Nigrum medicinal material coarse powder, add 12 times of water gagings, soak 30min in 80 ℃ of insulations, microwave extraction 20min under the 150W power filters, and it is 0.08g/ml that filtrating is diluted to crude drug content, promptly gets Semen Sesami Nigrum microwave extraction thing.
(6) Folium Artemisiae Argyi extract: get the Folium Artemisiae Argyi medicinal material coarse powder, add 8 times of water gagings, soak 30min in 80 ℃ of insulations, supersound extraction 20min under the 50w power filters, and it is 0.03g/ml that filtrating is diluted to crude drug content, promptly gets the Folium Artemisiae Argyi sonicated extract.
2, the preparation of dandruff-removing itching-relieve Chinese medicine composition:
Concentration is first Radix Paeoniae Rubra extract of 0.08g/ml, first Fructus Xanthii extract of 0.08g/ml, the Semen Sesami Nigrum extract of 0.08g/ml, is mixed with first Chinese medicine composition after mixing according to 1: 1: 1 volume ratio; Concentration is second Radix Paeoniae Rubra extract of 0.02g/ml, second Fructus Xanthii extract of 0.08g/ml, the Folium Artemisiae Argyi extract of 0.03g/ml, is mixed with second Chinese medicine composition after mixing according to 1: 1: 1 volume ratio; First Chinese medicine composition and second Chinese medicine composition promptly obtain the dandruff-removing itching-relieve Chinese medicine composition according to 2: 1 volume ratio mix homogeneously.
Embodiment 2
1, the preparation of Chinese medicine extract:
Method for preparing such as embodiment 1; Different is that the first Radix Paeoniae Rubra extract concentration of final preparation is that 0.04g/ml, the first Fructus Xanthii extract concentration are that 0.16g/ml, Semen Sesami Nigrum extract concentration are that 0.16g/ml, the second Radix Paeoniae Rubra extract concentration are that 0.04g/ml, the second Fructus Xanthii extract concentration are that 0.02g/ml, Folium Artemisiae Argyi extract concentration are 0.12g/ml.
2, the preparation of dandruff-removing itching-relieve Chinese medicine composition:
Concentration is first Radix Paeoniae Rubra extract of 0.04g/ml, first Fructus Xanthii extract of 0.16g/ml, the Semen Sesami Nigrum extract of 0.16g/ml, is mixed with first Chinese medicine composition after mixing according to 1: 2.5: 1 volume ratio; Concentration is the second Radix Paeoniae Rubra ripple extract of 0.04g/ml, second Fructus Xanthii extract of 0.02g/ml, the Folium Artemisiae Argyi extract of 0.12g/ml, is mixed with second Chinese medicine composition after mixing according to 2.5: 1: 1 volume ratios; First Chinese medicine composition mixes the back evenly with second Chinese medicine composition according to 5: 1 volume ratio, promptly obtains the dandruff-removing itching-relieve Chinese medicine composition.
Embodiment 3
1, the preparation of Chinese medicine extract:
Method for preparing such as embodiment 1; Different is that the first Radix Paeoniae Rubra extract concentration of final preparation is that 0.08g/ml, the first Fructus Xanthii extract concentration are that 0.08g/ml, Semen Sesami Nigrum extract concentration are that 0.12g/ml, the second Radix Paeoniae Rubra extract concentration are that 0.08g/ml, the second Fructus Xanthii extract concentration are that 0.1g/ml, Folium Artemisiae Argyi extract concentration are 0.03g/ml.
2, the preparation of dandruff-removing itching-relieve Chinese medicine composition:
Concentration is first Radix Paeoniae Rubra extract of 0.08g/ml, first Fructus Xanthii extract of 0.08g/ml, the Semen Sesami Nigrum extract of 0.12g/ml, is mixed with first Chinese medicine composition after mixing according to 2: 1: 1 volume ratios; Concentration is the second Radix Paeoniae Rubra ripple extract of 0.08g/ml, second Fructus Xanthii extract of 0.1g/ml, the Folium Artemisiae Argyi extract of 0.03g/ml, is mixed with second Chinese medicine composition after mixing according to 1: 2: 1 volume ratio; First Chinese medicine composition mixes the back evenly with second Chinese medicine composition according to 1: 1 volume ratio, promptly obtains the dandruff-removing itching-relieve Chinese medicine composition.
Embodiment 4
1, the preparation of Chinese medicine extract:
Method for preparing such as embodiment 1; Different is that the first Radix Paeoniae Rubra extract concentration of final preparation is that 0.16g/ml, the first Fructus Xanthii extract concentration are that 0.08g/ml, Semen Sesami Nigrum extract concentration are that 0.02g/ml, the second Radix Paeoniae Rubra extract concentration are that 0.18g/ml, the second Fructus Xanthii extract concentration are that 0.2g/ml, Folium Artemisiae Argyi extract concentration are 0.01g/ml.
2, the preparation of dandruff-removing itching-relieve Chinese medicine composition:
Concentration is first Radix Paeoniae Rubra extract of 0.16g/ml, first Fructus Xanthii extract of 0.08g/ml, the Semen Sesami Nigrum extract of 0.02g/ml, is mixed with first Chinese medicine composition after mixing according to 1: 5: 1 volume ratio; Concentration is the second Radix Paeoniae Rubra ripple extract of 0.18g/ml, second Fructus Xanthii extract of 0.2g/ml, the Folium Artemisiae Argyi extract of 0.01g/ml, is mixed with second Chinese medicine composition after mixing according to 5: 5: 1 volume ratios; First Chinese medicine composition mixes the back evenly with second Chinese medicine composition according to 3: 1 volume ratio, promptly obtains the dandruff-removing itching-relieve Chinese medicine composition.
Embodiment 5
1, the preparation of Chinese medicine extract:
Method for preparing such as embodiment 1; Different is that the first Radix Paeoniae Rubra extract concentration of final preparation is that 0.2g/ml, the first Fructus Xanthii extract concentration are that 0.2g/ml, Semen Sesami Nigrum extract concentration are that 0.2g/ml, the second Radix Paeoniae Rubra extract concentration are that 0.2g/ml, the second Fructus Xanthii extract concentration are that 0.1g/ml, Folium Artemisiae Argyi extract concentration are 0.2g/ml.
2, the preparation of dandruff-removing itching-relieve Chinese medicine composition:
Concentration is first Radix Paeoniae Rubra extract of 0.2g/ml, first Fructus Xanthii extract of 0.2g/ml, the Semen Sesami Nigrum extract of 0.2g/ml, is mixed with first Chinese medicine composition after mixing according to 5: 3: 1 weight ratios; Concentration is the second Radix Paeoniae Rubra ripple extract of 0.2g/ml, second Fructus Xanthii extract of 0.1g/ml, the Folium Artemisiae Argyi extract of 0.2g/ml, is mixed with second Chinese medicine composition after mixing according to 4: 5: 1 weight ratios; First Chinese medicine composition mixes the back evenly with second Chinese medicine composition according to 4: 1 weight ratio, promptly obtains the dandruff-removing itching-relieve Chinese medicine composition.
The dandruff-removing itching-relieve Chinese medicine composition for preparing in the embodiment of the invention; Can be added into shampoo, hair conditioner, send out in the Shampoo & Conditioners such as film, gel, elastin; The addition of Chinese medicine composition is the 7-10% of Shampoo & Conditioner weight, and the hair products of washing of the present invention's preparation have advantages such as safe, effective, non-stimulated.
Above-described embodiment, the present invention specific embodiment a kind of more preferably just, common variation that those skilled in the art carries out in technical scheme scope of the present invention and replacement all should be included in protection scope of the present invention.
Claims (7)
1. a dandruff-removing itching-relieve Chinese medicine composition is characterized in that, is made up of first Chinese medicine composition and second Chinese medicine composition, and the proportioning ratio of said first Chinese medicine composition and second Chinese medicine composition is 1～5: 1.
Said first Chinese medicine composition is mixed by first Radix Paeoniae Rubra extract, first Fructus Xanthii extract and Semen Sesami Nigrum extract:
The proportioning ratio of said first Radix Paeoniae Rubra extract, first Fructus Xanthii extract and Semen Sesami Nigrum extract is: 1～5: 1～5: 1;
Said second Chinese medicine composition mixes by stating second Radix Paeoniae Rubra extract, second Fructus Xanthii extract and Folium Artemisiae Argyi extract:
The proportioning ratio of second Radix Paeoniae Rubra extract, second Fructus Xanthii extract and Folium Artemisiae Argyi extract is: 1～5: 1～5: 1.
2. dandruff-removing itching-relieve Chinese medicine composition according to claim 1 is characterized in that:
The concentration of said first Radix Paeoniae Rubra extract, first Fructus Xanthii extract, Semen Sesami Nigrum extract, second Radix Paeoniae Rubra extract and second Fructus Xanthii extract is for being 0.02～0.2g/ml; The concentration of said Folium Artemisiae Argyi extract is for being 0.01～0.2g/ml.
3. dandruff-removing itching-relieve Chinese medicine composition according to claim 1 is characterized in that:
The concentration of said first Radix Paeoniae Rubra extract, first Fructus Xanthii extract, Semen Sesami Nigrum extract, second Radix Paeoniae Rubra extract and second Fructus Xanthii extract is for being 0.06～0.12g/ml; The concentration of said Folium Artemisiae Argyi extract is for being 0.01～0.12g/ml.
4. according to each described dandruff-removing itching-relieve Chinese medicine composition of claim 1-3, it is characterized in that: the extraction solvent of said extract is purified water or ethanol, and said proportioning ratio is volume ratio or weight ratio.
5. according to dandruff-removing itching-relieve Chinese medicine composition according to claim 4, it is characterized in that: said first Radix Paeoniae Rubra extract is a Radix Paeoniae Rubra microwave extraction thing; Said second Radix Paeoniae Rubra extract is a Radix Paeoniae Rubra ultrasonic extraction thing; Said first Fructus Xanthii extract is a Fructus Xanthii microwave extraction thing; Said second Fructus Xanthii extract is the Fructus Xanthii sonicated extract; Said Semen Sesami Nigrum extract is a Semen Sesami Nigrum microwave extraction thing; Said Folium Artemisiae Argyi extract is a Folium Artemisiae Argyi ultrasonic extraction thing.
6. the described dandruff-removing itching-relieve Chinese medicine composition of claim 1 is used to wash the purposes of hair products.
7. purposes according to claim 6 is characterized in that: the said hair products of washing are selected from shampoo, hair conditioner, send out a kind of in film, gel water, the elastin.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103536487A (en) * | 2013-10-18 | 2014-01-29 | 桂林雪芙莲日化有限公司 | Anti-dandruff shampo |
| CN110237146A (en) * | 2019-07-09 | 2019-09-17 | 上海中医大生物科技有限公司 | A kind of Chinese medicine composition and preparation method thereof for dispelling dandruff |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732488A (en) * | 2008-11-17 | 2010-06-16 | 李宝霞 | Hair nourishing composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101732488A (en) * | 2008-11-17 | 2010-06-16 | 李宝霞 | Hair nourishing composition |
Non-Patent Citations (1)
| Title |
|---|
| 秦万章: "中西医结合治疗脱发研究进展", 《2002中国中西医结合皮肤性病学术会议论文汇编》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103536487A (en) * | 2013-10-18 | 2014-01-29 | 桂林雪芙莲日化有限公司 | Anti-dandruff shampo |
| CN110237146A (en) * | 2019-07-09 | 2019-09-17 | 上海中医大生物科技有限公司 | A kind of Chinese medicine composition and preparation method thereof for dispelling dandruff |
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