CN105326707A - Radix stemonae traditional Chinese medicine hand sanitizer and preparation method thereof - Google Patents
Radix stemonae traditional Chinese medicine hand sanitizer and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
A radix stemonae traditional Chinese medicine hand sanitizer is prepared from the following components in percentage by weight: 1-5 percent of artemisia argyi extract, 1-5 percent of radix sophorae flavescentis extract, 1-5 percent of borneol extract, 5-10 percent of radix stemonae extract, 1-5 percent of lithospermum extract, 1-5 percent of radix paeoniae alba extract, 5 percent-10 percent of sodium laureth sulfate, 5 percent-10 percent of cocamidopropyl betaine, 0.5-3 percent of mint oil, 0.5-3 percent of olive oil, 1-5 percent of glycerinum and the balance of deionized water. A preparation method comprises: preparation of the artemisia argyi extract, preparation of the radix sophorae flavescentis extract, preparation of the radix stemonae extract, preparation of the lithospermum extract, preparation of the radix paeoniae alba extract, preparation of oil phase, preparation of water phase and preparation of a sanitizer. The radix stemonae traditional Chinese medicine hand sanitizer has good functions of sterilizing and relieving itching, can provide protection for the skin, and is suitable for being used for a long term.
Description
Technical field
The present invention relates to a kind of daily chemical products.
Background technology
Handwashing liquid comes into huge numbers of families as the upgraded product of fancy soap.The function ratio of most of handwashing liquid is more single, based on decontamination.The handwashing liquid with specific function is also realize by adding predetermined substance, and so easy generation skin allergy, skin is clamminess, punching does not wash clean, hands easily causes again after doing that hand is astringent, the coarse easily phenomenon such as aging of hand.The use for a long time of such handwashing liquid can bring injury to hand skin.
Summary of the invention
For above-mentioned technical problem, the invention provides a kind of Radix Stemonae Traditional Chinese medicinal hand lotion and preparation method thereof.Radix Stemonae Traditional Chinese medicinal hand lotion of the present invention is made up of the component of following percentage by weight: Folium Artemisiae Argyi extract 1 ~ 5%, Radix Sophorae Flavescentis extract 1 ~ 5%, Borneolum Syntheticum 1 ~ 5%, Radix Stemonae extract 5 ~ 10%, Radix Arnebiae extract 1 ~ 5%, Radix Paeoniae Alba extract 1 ~ 5%, sodium laureth sulfate 5% ~ 10%, cocamido propyl betaine 5% ~ 10%, Oleum menthae 0.5 ~ 3%, olive oil 0.5 ~ 3%, glycerol 1 ~ 5%, deionized water surplus.
Further, be made up of the component of following percentage by weight: Folium Artemisiae Argyi extract 2 ~ 4%, Radix Sophorae Flavescentis extract 2 ~ 4%, Borneolum Syntheticum 2 ~ 4%, Radix Stemonae extract 6 ~ 9%, Radix Arnebiae extract 2 ~ 4%, Radix Paeoniae Alba extract 2 ~ 4%, sodium laureth sulfate 6% ~ 9%, cocamido propyl betaine 6% ~ 9%, Oleum menthae 0.8 ~ 2%, olive oil 0.8 ~ 2%, glycerol 2 ~ 4%, deionized water surplus.
Particularly, be made up of the component of following percentage by weight: Folium Artemisiae Argyi extract 3%, Radix Sophorae Flavescentis extract 3%, Borneolum Syntheticum 3%, Radix Stemonae extract 8%, Radix Arnebiae extract 3%, Radix Paeoniae Alba extract 3%, sodium laureth sulfate 8%, cocamido propyl betaine 7%, Oleum menthae 1%, olive oil 1%, glycerol 3%, deionized water surplus.
The preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion of the present invention comprises the following steps:
(1). the preparation of oil phase: by described formula ratio, under stirring, is mixed and heated to 60 ~ 75 DEG C by Borneolum Syntheticum, Oleum menthae, olive oil and glycerol;
(2). the preparation of aqueous phase: by described formula ratio, under stirring, Folium Artemisiae Argyi extract, Radix Sophorae Flavescentis extract, Radix Stemonae extract, Radix Arnebiae extract, Radix Paeoniae Alba extract, sodium laureth sulfate, cocamido propyl betaine and deionized water are mixed into uniform solution, are heated to 60 ~ 75 DEG C;
(3). the preparation of handwashing liquid: under insulation, the oil phase that step (1) is obtained is slowly added in the obtained aqueous phase of step (2), continue stirring and make it homogenize, and discharging after being slowly down to room temperature.
Particularly, the preparation method of described Radix Sophorae Flavescentis extract is: Radix Sophorae Flavescentis is pulverized after cleaning, and is added by Lightyellow Sophora Root in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtain filtrate a, insoluble matter is added in the water of 3 times of weight, reflux, extract, 1 ~ 2h again, elimination insoluble matter, filtrate b, merging filtrate a and filtrate b, to be evaporated to relative density be the solution of 1.1 ~ 1.2 and get final product.
Particularly, the preparation method of described Folium Artemisiae Argyi extract is: Folium Artemisiae Argyi is pulverized after cleaning, volume fraction Argy Wormwood Leaf being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, and elimination insoluble matter obtains filtrate c, insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtains filtrate d, merging filtrate c and filtrate d, is evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
Particularly, the preparation method of described Radix Stemonae extract is: the Radix Stemonae is pulverized after cleaning, volume fraction Stemona Root being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, and elimination insoluble matter obtains filtrate e, insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtains filtrate f, merging filtrate e and filtrate f, is evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
Particularly, the preparation method of described Radix Arnebiae extract is: Radix Arnebiae (Radix Lithospermi) is pulverized after cleaning, volume fraction Arnebia Root being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, and elimination insoluble matter obtains filtrate g, insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtains filtrate h, merging filtrate g and filtrate h, is evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
Particularly, the preparation method of described Radix Paeoniae Alba extract is: the Radix Paeoniae Alba is pulverized after cleaning, and is added by White Peony Root in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtain filtrate i, insoluble matter is added in the water of 3 times of weight, reflux, extract, 1 ~ 2h again, elimination insoluble matter, filtrate j, merging filtrate i and filtrate j, to be evaporated to relative density be the solution of 1.1 ~ 1.2 and get final product.
Radix Arnebiae (Radix Lithospermi) is cold in nature, bitter in the mouth, enters percardium, Liver Channel.Can removing heat from blood, invigorate blood circulation, heat clearing away, removing toxic substances.Control warm macule, jaundice due to damp-heat, purpura, burn, eczema, erysipelas, carbuncle and ulcer etc.Radix Arnebiae (Radix Lithospermi) in vitro has inhibitory action to capital section 68-1 virus, also can suppress staphylococcus aureus, Bacterium prodigiosum.Tincture has inhibitory action to pyogenic baeceria, escherichia coli.And epithelial growth and treatment burn can be accelerated.
Radix Stemonae sweet in the mouth, hardship, slightly warm in nature; Return lung meridian.There is nourishing the lung to keep the adverse QI downward cough-relieving, effect of parasite killing delousing.Outer for head louse, body louse, enterobiasis, pudendal pruritus.
The Radix Paeoniae Alba is cool in nature, and bitter in the mouth acid, is slightly cold, has the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating.Paeoniflorin has effect that is antibacterial, antipyretic and anti-inflammatory, and Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
Radix Stemonae Traditional Chinese medicinal hand lotion temperature of the present invention is pure and fresh, and color is salubrious.Folium Artemisiae Argyi has antipruritic effect of drying, and the Radix Stemonae and Radix Sophorae Flavescentis can kill some infusorian, and the Radix Paeoniae Alba and Radix Arnebiae (Radix Lithospermi) also have sterilizing function; Coordinate olive oil and the glycerol with skin-protecting function, Radix Stemonae Traditional Chinese medicinal hand lotion of the present invention has good sterilizing and itch-relieving function, can provide protection to skin simultaneously, is applicable to life-time service.
In order to understand better and implement, the following detailed description of the present invention.
Detailed description of the invention
preparation embodiment
The preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion of the present invention comprises the following steps:
1. the preparation of Radix Sophorae Flavescentis extract: Radix Sophorae Flavescentis is pulverized after cleaning, Lightyellow Sophora Root is added in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtains filtrate a, insoluble matter is added again in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtains filtrate b, merging filtrate a and filtrate b, to be evaporated to relative density be the solution of 1.1 ~ 1.2 and get final product.
2. the preparation of Folium Artemisiae Argyi extract: Folium Artemisiae Argyi is pulverized after cleaning, volume fraction Argy Wormwood Leaf being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter obtains filtrate c, and insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtain filtrate d, merging filtrate c and filtrate d, be evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
3. the preparation of Radix Stemonae extract: the Radix Stemonae is pulverized after cleaning, volume fraction Stemona Root being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter obtains filtrate e, and insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtain filtrate f, merging filtrate e and filtrate f, be evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
4. the preparation of Radix Arnebiae extract: Radix Arnebiae (Radix Lithospermi) is pulverized after cleaning, volume fraction Arnebia Root being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter obtains filtrate g, and insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtain filtrate h, merging filtrate g and filtrate h, be evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
5. the preparation side of Radix Paeoniae Alba extract: the Radix Paeoniae Alba is pulverized after cleaning, White Peony Root is added in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtains filtrate i, insoluble matter is added again in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtains filtrate j, merging filtrate i and filtrate j, to be evaporated to relative density be the solution of 1.1 ~ 1.2 and get final product.
6. the preparation of oil phase: by table 1 formula ratio, under stirring, is mixed and heated to 60 ~ 75 DEG C by Borneolum Syntheticum, Oleum menthae, olive oil and glycerol;
7. the preparation of aqueous phase: by table 1 formula ratio, under stirring, Folium Artemisiae Argyi extract, Radix Sophorae Flavescentis extract, Radix Stemonae extract, Radix Arnebiae extract, Radix Paeoniae Alba extract, sodium laureth sulfate, cocamido propyl betaine and deionized water are mixed into uniform solution, are heated to 60 ~ 75 DEG C;
8. the preparation of handwashing liquid: slowly added in the obtained aqueous phase of step (2) by the oil phase that step (1) is obtained under insulation, continues stirring and makes it homogenize, and discharging after being slowly down to room temperature.
The each component formula amount of < table 1, > by weight percentage
bactericidal effect embodiment
The antibacterial effect of the bath gel of the embodiment of the present invention 1 ~ 5 and comparative example 1 preparation is measured according to GB19877.2-2005 " extraordinary bath shampoo " and GB15979-2002 " Disposable Sanitary Accessory sanitary standard " appendix C.
Test organisms: antibacterial: staphylococcus aureus (ATCC6538), escherichia coli (ATCC25922);
Yeast: Candida albicans (ATCC10231).
Bacterium solution preparation: the nutrient agar inclined-plane fresh cultured thing 18 ~ 24h getting bacterial strain 3rd ~ 14 generation, washes lower lawn with 5ml0.03mol/L phosphate buffer (hereinafter referred to as PBS), bacterium is suspended evenly and is diluted to desired concn with above-mentioned PBS.
Operating procedure:
Washed down by test organisms 24h slant culture PBS, make bacteria suspension, the concentration of requirement is: drip on contrast print with 100 μ l, bacterial count recovered is 1 × 10
4~ 9 × 10
4cfu/ sheet.
Get by coupons (2.0cm × 3.0cm) and contrast each 4 of print, be divided into 4 groups and be placed in 4 sterilizing plates.Described contrast print and sample homogeneous material, equal size, but not containing anti-biotic material, and through sterilization treatment.
Get above-mentioned bacteria suspension. dripped 100 μ l each by coupons and contrast print respectively, even spread, start timing, effect 2min, respectively print is thrown people containing 5m1 with aseptic tweezer, corresponding nertralizer in vitro, abundant mixing, do suitably dilution, then wherein 2-3 dilution factor is got, draw 0.5ml respectively, be placed in two plates, pour into cool nutrient agar (antibacterial) to 40-45' DEG C or sabouraud's agar (yeast) 15m1, rotate plate, make it full and uniform, after agar solidification, upset is dull and stereotyped, 35 DEG C of scholars, 2 DEG C of cultivations 48h (antibacterial) or 72h (yeast), do viable bacteria colony counting.Test repetition 3 times, is calculated as follows sterilizing rate: X=(A-B)/A × 100%
In formula: X---sterilizing rate, %;
A---control sample average colony number;
The tested sample average clump count of B---.
Evaluation criterion: sterilizing rate >=90%, product has bactericidal action.Result is as following table 2:
< table 2 sterilizing rate, activity is 1:1>
* compare for comparative example 1, p < 0.05.
skin effect embodiment
Utilize the skin-care effect feeling the Radix Stemonae Traditional Chinese medicinal hand lotion come obtained by Evaluation operation example 1 ~ 5.Choose 50 ages the women of 20 ~ 50 years old as object on probation, stochastic averagina is divided into 5 groups, often organizes 10 people.Use every day the obtained skin care hand cleaning liquid of embodiment 1 ~ 5 to absorb respectively, every day, access times were determined as required, used 1 month altogether.Then used Radix Stemonae Traditional Chinese medicinal hand lotion is given a mark.Every result of use total score is 5 points: 5 be divided into best result, represents very well; 4 are divided into better; 3 are divided into and can accept; 2 be divided into bad; 1 is divided into and can not accepts.Be below every average, the results are shown in Table 2.Can draw, the skin effect of trier to Radix Stemonae Traditional Chinese medicinal hand lotion of the present invention has higher rating.
< table 3 effect expedition >
The present invention is not limited to above-mentioned embodiment, if do not depart from the spirit and scope of the present invention to various change of the present invention or distortion, if these are changed and distortion belongs within claim of the present invention and equivalent technologies scope, then the present invention is also intended to comprise these changes and distortion.
Claims (9)
1. a Radix Stemonae Traditional Chinese medicinal hand lotion, is characterized in that being made up of the component of following percentage by weight: Folium Artemisiae Argyi extract 1 ~ 5%, Radix Sophorae Flavescentis extract 1 ~ 5%, Borneolum Syntheticum 1 ~ 5%, Radix Stemonae extract 5 ~ 10%, Radix Arnebiae extract 1 ~ 5%, Radix Paeoniae Alba extract 1 ~ 5%, sodium laureth sulfate 5% ~ 10%, cocamido propyl betaine 5% ~ 10%, Oleum menthae 0.5 ~ 3%, olive oil 0.5 ~ 3%, glycerol 1 ~ 5%, deionized water surplus.
2. Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 1, is characterized in that being made up of the component of following percentage by weight: Folium Artemisiae Argyi extract 2 ~ 4%, Radix Sophorae Flavescentis extract 2 ~ 4%, Borneolum Syntheticum 2 ~ 4%, Radix Stemonae extract 6 ~ 9%, Radix Arnebiae extract 2 ~ 4%, Radix Paeoniae Alba extract 2 ~ 4%, sodium laureth sulfate 6% ~ 9%, cocamido propyl betaine 6% ~ 9%, Oleum menthae 0.8 ~ 2%, olive oil 0.8 ~ 2%, glycerol 2 ~ 4%, deionized water surplus.
3. Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 2, is characterized in that being made up of the component of following percentage by weight: Folium Artemisiae Argyi extract 3%, Radix Sophorae Flavescentis extract 3%, Borneolum Syntheticum 3%, Radix Stemonae extract 8%, Radix Arnebiae extract 3%, Radix Paeoniae Alba extract 3%, sodium laureth sulfate 8%, cocamido propyl betaine 7%, Oleum menthae 1%, olive oil 1%, glycerol 3%, deionized water surplus.
4. prepare a method for the Radix Stemonae Traditional Chinese medicinal hand lotion described in claims 1 to 3 any one, it is characterized in that comprising the following steps:
(1). the preparation of oil phase: by described formula ratio, under stirring, is mixed and heated to 60 ~ 75 DEG C by Borneolum Syntheticum, Oleum menthae, olive oil and glycerol;
(2). the preparation of aqueous phase: by described formula ratio, under stirring, Folium Artemisiae Argyi extract, Radix Sophorae Flavescentis extract, Radix Stemonae extract, Radix Arnebiae extract, Radix Paeoniae Alba extract, sodium laureth sulfate, cocamido propyl betaine and deionized water are mixed into uniform solution, are heated to 60 ~ 75 DEG C;
(3). the preparation of handwashing liquid: under insulation, the oil phase that step (1) is obtained is slowly added in the obtained aqueous phase of step (2), continue stirring and make it homogenize, and discharging after being slowly down to room temperature.
5. the preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 4, it is characterized in that the preparation method of described Radix Sophorae Flavescentis extract is: Radix Sophorae Flavescentis is pulverized after cleaning, and is added by Lightyellow Sophora Root in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtain filtrate a, insoluble matter is added in the water of 3 times of weight, reflux, extract, 1 ~ 2h again, elimination insoluble matter, filtrate b, merging filtrate a and filtrate b, to be evaporated to relative density be the solution of 1.1 ~ 1.2 and get final product.
6. the preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 4, it is characterized in that the preparation method of described Folium Artemisiae Argyi extract is: Folium Artemisiae Argyi is pulverized after cleaning, volume fraction Argy Wormwood Leaf being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter obtains filtrate c, insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtain filtrate d, merging filtrate c and filtrate d, is evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
7. the preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 4, it is characterized in that the preparation method of described Radix Stemonae extract is: the Radix Stemonae is pulverized after cleaning, volume fraction Stemona Root being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter obtains filtrate e, insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtain filtrate f, merging filtrate e and filtrate f, is evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
8. the preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 4, it is characterized in that the preparation method of described Radix Arnebiae extract is: Radix Arnebiae (Radix Lithospermi) is pulverized after cleaning, volume fraction Arnebia Root being added 3 times of weight is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter obtains filtrate g, insoluble matter being added again volume fraction is in the alcoholic solution of 50%, supersound extraction 20 ~ 30min, elimination insoluble matter, obtain filtrate h, merging filtrate g and filtrate h, is evaporated to 1/2 of filtrate cumulative volume after merging and get final product.
9. the preparation method of Radix Stemonae Traditional Chinese medicinal hand lotion according to claim 4, it is characterized in that the preparation method of described Radix Paeoniae Alba extract is: the Radix Paeoniae Alba is pulverized after cleaning, and is added by White Peony Root in the water of 3 times of weight, reflux, extract, 1 ~ 2h, elimination insoluble matter, obtain filtrate i, insoluble matter is added in the water of 3 times of weight, reflux, extract, 1 ~ 2h again, elimination insoluble matter, filtrate j, merging filtrate i and filtrate j, to be evaporated to relative density be the solution of 1.1 ~ 1.2 and get final product.
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| CN106978287A (en) * | 2017-04-16 | 2017-07-25 | 洪艳 | Hand soaps and preparation method thereof |
| CN106978286A (en) * | 2017-04-16 | 2017-07-25 | 洪艳 | Suppress hand soaps of perspiration and preparation method thereof |
| CN107099403A (en) * | 2017-04-16 | 2017-08-29 | 洪艳 | Economic benefits and social benefits hand soaps and preparation method thereof |
| CN107129884A (en) * | 2017-04-16 | 2017-09-05 | 洪艳 | Prevent hand soaps of infant eczema and preparation method thereof |
| CN108379151A (en) * | 2018-04-13 | 2018-08-10 | 南京正宽医药科技有限公司 | A kind of plant hand sanitizer |
| CN112263652A (en) * | 2020-11-09 | 2021-01-26 | 杭州宏果科技有限公司 | Traditional Chinese medicine antibacterial liquid and preparation method and application thereof |
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