CN102413839A - 人源化抗cd19抗体制剂 - Google Patents
人源化抗cd19抗体制剂 Download PDFInfo
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- CN102413839A CN102413839A CN2010800197310A CN201080019731A CN102413839A CN 102413839 A CN102413839 A CN 102413839A CN 2010800197310 A CN2010800197310 A CN 2010800197310A CN 201080019731 A CN201080019731 A CN 201080019731A CN 102413839 A CN102413839 A CN 102413839A
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15815309P | 2009-03-06 | 2009-03-06 | |
| US61/158,153 | 2009-03-06 | ||
| PCT/US2010/026492 WO2010102276A2 (en) | 2009-03-06 | 2010-03-08 | Humanized anti-cd19 antibody formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102413839A true CN102413839A (zh) | 2012-04-11 |
Family
ID=42710248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800197310A Pending CN102413839A (zh) | 2009-03-06 | 2010-03-08 | 人源化抗cd19抗体制剂 |
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| Country | Link |
|---|---|
| US (1) | US20120148576A1 (enExample) |
| EP (1) | EP2403532A4 (enExample) |
| JP (1) | JP2012519712A (enExample) |
| KR (1) | KR20110125664A (enExample) |
| CN (1) | CN102413839A (enExample) |
| AU (1) | AU2010221099A1 (enExample) |
| BR (1) | BRPI1013237A2 (enExample) |
| CA (1) | CA2754266A1 (enExample) |
| MX (1) | MX2011009312A (enExample) |
| RU (1) | RU2011140486A (enExample) |
| WO (1) | WO2010102276A2 (enExample) |
| ZA (1) | ZA201106480B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113208810A (zh) * | 2021-05-18 | 2021-08-06 | 南方医科大学深圳医院 | Smile术透镜染色低温分离液、应用及其使用方法 |
| WO2022142053A1 (en) * | 2020-12-30 | 2022-07-07 | I-Mab Biopharma Co., Ltd | Formulations of anti-cd73 antibodies |
| CN115232208A (zh) * | 2021-04-23 | 2022-10-25 | 上海君实生物医药科技股份有限公司 | 抗BLyS抗体、其药物组合物及其用途 |
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| KR101462693B1 (ko) * | 2006-08-16 | 2014-11-17 | 노파르티스 아게 | 고도 결정질 치료용 화합물의 고체 분산체 제조 방법 |
| UY32560A (es) | 2009-04-29 | 2010-11-30 | Bayer Schering Pharma Ag | Inmunoconjugados de antimesotelina y usos de los mismos |
| MY161534A (en) * | 2010-05-25 | 2017-04-28 | Genentech Inc | Methods of purifying polypeptides |
| US20130195851A1 (en) * | 2011-12-23 | 2013-08-01 | Genentech, Inc. | Articles of manufacture and methods for co-administration of antibodies |
| WO2013138244A2 (en) * | 2012-03-12 | 2013-09-19 | Medimmune, Llc | Treatment of multiple sclerosis with anti-cd19 antibody |
| EP2841128A4 (en) * | 2012-04-23 | 2015-11-25 | Zogenix Inc | PISTON CLOSURES FOR MEDICINAL PACKAGING CAPSULES |
| BR112015000657B1 (pt) * | 2012-07-13 | 2023-12-05 | The Trustees Of The University Of Pennsylvania | Uso de uma célula geneticamente modificada para expressar um car |
| AU2013201465B2 (en) * | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| BR112015022210A8 (pt) * | 2013-03-13 | 2018-01-23 | Genentech Inc | formulações de anticorpo |
| SG11201607306PA (en) * | 2014-04-07 | 2016-09-29 | Seattle Genetics Inc | Stable formulations for anti-cd19 antibodies and antibody-drug conjugates |
| US10206878B2 (en) * | 2014-05-28 | 2019-02-19 | Nono Inc. | Lyophilized formulation of TAT-NR2B9C with acetylation scavenger |
| JP7072384B2 (ja) | 2014-09-15 | 2022-05-20 | ジェネンテック， インコーポレイテッド | 抗体製剤 |
| TWI809304B (zh) | 2014-12-01 | 2023-07-21 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| US11091543B2 (en) | 2015-05-07 | 2021-08-17 | Swedish Orphan Biovitrum Ag | Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications |
| CA2985001A1 (en) | 2015-05-07 | 2016-11-10 | Novimmune Sa | Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of cxcl9 and other biomarkers |
| AR104847A1 (es) * | 2015-06-17 | 2017-08-16 | Lilly Co Eli | Formulación de anticuerpo anti-cgrp |
| WO2017015783A1 (en) * | 2015-07-24 | 2017-02-02 | Shanghai Sidansai Biotechnology Co., Ltd | Humanized anti-cd19 antibody and use thereof |
| US10493139B2 (en) | 2015-07-24 | 2019-12-03 | Innovative Cellular Therapeutics CO., LTD. | Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor |
| SG11201810429UA (en) * | 2016-06-27 | 2018-12-28 | Morphosys Ag | Anti-cd19 antibody formulations |
| EP3330289A1 (en) * | 2016-12-02 | 2018-06-06 | Friedrich-Alexander-Universität Erlangen-Nürnberg | A cd33-, cd16- and cd123-specific single chain triplebody |
| KR20230144110A (ko) | 2017-03-02 | 2023-10-13 | 제넨테크, 인크. | Her2-양성 유방암 어쥬번트 치료 |
| JOP20190260A1 (ar) * | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| SG11201909955XA (en) | 2017-05-02 | 2019-11-28 | Merck Sharp & Dohme | Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies |
| CN110945028B (zh) | 2017-07-10 | 2023-09-08 | 国际药物发展生物技术公司 | 用非岩藻糖基化促凋亡抗cd19抗体与抗cd20抗体或化疗剂联合治疗b细胞恶性肿瘤 |
| CA3083936C (en) * | 2017-12-06 | 2022-08-23 | Abclon Inc. | Anti-cd19 antibody or antigen-binding fragment and cd19-specific chimeric antigen receptor comprising the same |
| EP3876990A4 (en) | 2018-11-07 | 2023-09-06 | Merck Sharp & Dohme LLC | CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES |
| MX2021009851A (es) | 2019-02-18 | 2021-09-10 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos. |
| SG11202111429UA (en) * | 2019-04-24 | 2021-11-29 | Viela Bio Inc | Use of an anti-cd19 antibody to treat autoimmune disease |
| WO2021067598A1 (en) | 2019-10-04 | 2021-04-08 | Ultragenyx Pharmaceutical Inc. | Methods for improved therapeutic use of recombinant aav |
| KR20220092578A (ko) * | 2019-11-05 | 2022-07-01 | 브리스톨-마이어스 스큅 컴퍼니 | M-단백질 검정 및 이의 용도 |
| WO2022026914A1 (en) * | 2020-07-31 | 2022-02-03 | Alamab Therapeutics, Inc. | Anti-connexin antibody formulations |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008031056A2 (en) * | 2006-09-08 | 2008-03-13 | Medimmune, Llc | Humanized anti-cd19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6171586B1 (en) * | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| EP1648512A4 (en) * | 2003-07-31 | 2009-01-21 | Immunomedics Inc | ANTI-CD19 ANTIBODIES |
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2010
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- 2010-03-08 CN CN2010800197310A patent/CN102413839A/zh active Pending
- 2010-03-08 JP JP2011553163A patent/JP2012519712A/ja not_active Withdrawn
- 2010-03-08 CA CA2754266A patent/CA2754266A1/en not_active Abandoned
- 2010-03-08 WO PCT/US2010/026492 patent/WO2010102276A2/en not_active Ceased
- 2010-03-08 BR BRPI1013237A patent/BRPI1013237A2/pt not_active IP Right Cessation
- 2010-03-08 KR KR1020117023323A patent/KR20110125664A/ko not_active Withdrawn
- 2010-03-08 MX MX2011009312A patent/MX2011009312A/es not_active Application Discontinuation
- 2010-03-08 AU AU2010221099A patent/AU2010221099A1/en not_active Abandoned
- 2010-03-08 US US13/254,656 patent/US20120148576A1/en not_active Abandoned
- 2010-03-08 EP EP10749432A patent/EP2403532A4/en not_active Withdrawn
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2011
- 2011-09-05 ZA ZA2011/06480A patent/ZA201106480B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008031056A2 (en) * | 2006-09-08 | 2008-03-13 | Medimmune, Llc | Humanized anti-cd19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022142053A1 (en) * | 2020-12-30 | 2022-07-07 | I-Mab Biopharma Co., Ltd | Formulations of anti-cd73 antibodies |
| CN115232208A (zh) * | 2021-04-23 | 2022-10-25 | 上海君实生物医药科技股份有限公司 | 抗BLyS抗体、其药物组合物及其用途 |
| CN113208810A (zh) * | 2021-05-18 | 2021-08-06 | 南方医科大学深圳医院 | Smile术透镜染色低温分离液、应用及其使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI1013237A2 (pt) | 2019-09-24 |
| JP2012519712A (ja) | 2012-08-30 |
| KR20110125664A (ko) | 2011-11-21 |
| MX2011009312A (es) | 2012-02-29 |
| AU2010221099A1 (en) | 2011-09-22 |
| EP2403532A2 (en) | 2012-01-11 |
| US20120148576A1 (en) | 2012-06-14 |
| RU2011140486A (ru) | 2013-04-20 |
| CA2754266A1 (en) | 2010-09-10 |
| ZA201106480B (en) | 2012-06-27 |
| WO2010102276A2 (en) | 2010-09-10 |
| WO2010102276A3 (en) | 2010-11-11 |
| EP2403532A4 (en) | 2012-12-05 |
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Application publication date: 20120411 |