CN102365957A - Uniconazole microemulsion as well as preparation method and application thereof - Google Patents
Uniconazole microemulsion as well as preparation method and application thereof Download PDFInfo
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- CN102365957A CN102365957A CN2011102698457A CN201110269845A CN102365957A CN 102365957 A CN102365957 A CN 102365957A CN 2011102698457 A CN2011102698457 A CN 2011102698457A CN 201110269845 A CN201110269845 A CN 201110269845A CN 102365957 A CN102365957 A CN 102365957A
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Abstract
The invention discloses a uniconazole microemulsion as well as a preparation method and application thereof. The uniconazole microemulsion comprises the following components: uniconazole, a solvent, a surfactant, a cosurfactant, an antifreeze agent and water. The uniconazole microemulsion disclosed by the invention is in nanometer level, and has the advantages of obvious seed-soaking dwarf effect at the seedling stage, good stability, small and even grain diameter, high drug effect, high transmission efficiency and permeability, and is beneficial to plant absorption and better development of drug effect.
Description
Technical field
The present invention relates to a plant growth regulators, relate in particular to a kind of nanoscale uniconazole P microemulsion.
Background technology
The uniconazole P chemical name: (E)-(RS)-1-rubigan-2-(1,2, the 4-triazol-1-yl)-4,4-dimethyl-1-amylene-3-alcohol.
Structural formula:
Uniconazole P is a kind of triazole type plant growth regulator, sees from physiology and molecular level, and the main activity of synthesizing and influencing indoleacetic acid oxidase that suppresses gibberellin of leaning on is come coordinate plant growth.Its biological effect has dwarfed plant, and is resistant to lodging, antiviral, sterilization etc.Draft or woody unifacial leaf or dicotyledon are had strong growth inhibition effect, and application method can adopt root to execute, spray and plant the bud impregnating.
Microemulsion is a kind of environmentally-friendly water-basedization reagent that China occurred in recent years, its good stability; Use no or little solvent, environmental pollution is little; Its particle diameter is very little, generally between 10～100nm, belongs to nanoscale; Have high transmission efficiency and permeability, help the absorption of plant, better bring into play drug effect.
With the most use in the market is 5% uniconazole P wetting powder, and its product cut size is big, and poor adhesion exists contaminated environment, diminishes problems such as operator ' s health in the use.200510090044.9 disclose the first piperazine is mixed the micro-emulsion formulation as active ingredient with uniconazole P, still, up to now, one pack system is not also appeared in the newspapers the microemulsion of uniconazole P as active ingredient.
Summary of the invention
The object of the present invention is to provide a kind of is the microemulsion formulation of active ingredient with the uniconazole P, and the preparation method of said preparation is provided.
For achieving the above object, the present invention adopts following technical scheme: a kind of uniconazole P microemulsion, form by following component by mass percentage:
Said uniconazole P is the commercial goods, contains 92% former medicine;
Said solvent comprises aromatic hydrocarbons, like benzene,toluene,xylene etc.; Alcohols is like methyl alcohol, ethanol, n-butanol etc.; Ketone is like acetone, cyclohexanone etc.; The ester class is like ethyl acetate; Polar solvent, like N, dinethylformamide, dimethyl sulfoxide (DMSO); It perhaps is several kinds combination in the above-mentioned solvent;
Said surfactant is one or more the composition among dodecyl sodium sulfate, Tween-80, Tween-60, AEO-9, the OP-10, and wherein AEO-9 is an AEO, and the main component of OP-10 is an APES;
Said cosurfactant is a kind of in methyl alcohol, ethanol, isopropyl alcohol, n-butanol, the n-amyl alcohol;
Said antifreeze is an ethylene glycol;
Said water is a kind of in deionized water, standard hard water or the running water.
The used chemical reagent of the present invention is the commercial goods.
The preparation method of uniconazole P microemulsion; Uniconazole P is fully mixed with solvent, surfactant, cosurfactant and antifreeze in proportion, under agitation slowly add entry, in 40 ℃ of following heated and stirred 30min; System changes into the O/W type by w/o type, and the room temperature cooling promptly gets.
Uniconazole P microemulsion provided by the invention is a nanoscale, seedling stage seed soaking downgrade effect obviously and good stability, particle diameter is little and even, drug effect is high, dilutable water, has high transmission efficiency and permeability, help the absorption of plant, better bring into play drug effect.And uniconazole P microemulsion preparation provided by the invention and method for using are simple, are a kind of environmentally-friendly water-basedization reagent, are that the ideal of 5% uniconazole P wetting powder substitutes formulation.
The present invention has tree-like, pot flowers flower bud differentiation, and the bactericidal and herbicidal effect of control fruit tree; In addition, also studied the regulating and controlling effect of uniconazole P microemulsion to crop wheat and mung bean seedling early growth.Therefore, another object of the present invention is the application of open uniconazole P microemulsion in wheat and the regulation and control of mung bean seedling early growth.
Description of drawings
Fig. 1 is 100 times of uniconazole P microemulsion dilutions of the present invention, amplifies 20,000 times transmission electron microscope picture.
As can be seen from the figure the phase particle is spherical and is evenly distributed that average grain diameter is 63.4nm, belongs to nanometer formulation in the micro emulsion.
Embodiment
Embodiment 1
A kind of uniconazole P microemulsion, form by following component by mass percentage:
Said components is fully mixed in proportion, under agitation slowly add entry, in 40 ℃ of following heated and stirred 30min, system changes into the O/W type by w/o type, and the room temperature cooling promptly gets.
Embodiment 2
A kind of uniconazole P microemulsion, form by following component by mass percentage:
Said components is fully mixed in proportion, under agitation slowly add entry, in 40 ℃ of following heated and stirred 30min, system changes into the O/W type by w/o type, and the room temperature cooling promptly gets.
Embodiment 3
Uniconazole P microemulsion provided by the invention is diluted to concentration 0.25mg/L, 0.5mg/L, 1.0mg/L, 2.0mg/L acts on the wheat seedling.
1. to the influence of wheat germination gesture and germination rate
Germination vigor, germination rate are the indexs that detects the seed sprouting quality.In 25 ℃ of camera bellows, cultivate, concentration is that microemulsion when seed soaking germination vigor of 1.0mg/L has increased by 5.82% than the wetting powder contrast, has reduced by 14.29% than the clear water contrast; 1.0mg/L germination rate is higher down for the seed soaking of concentration microemulsion, is 86.65%.Result of study shows that under the seed soaking of uniconazole P microemulsion, wheat seed germinating is neat.Concrete experimental data is seen table 1 and table 2.
Table 1 wheat seed germinating gesture
Table 2 wheat seed germinating rate
2. to the influence of wheat seedling form
When testing the 14th day, the height of seedling of 1.0mg/L concentration microemulsion seed soaking has reduced by 5.28% than the wetting powder contrast; Reduced by 34.05% than the clear water contrast; Root length has increased by 11.75% than wetting powder, has increased by 48.40% than clear water.Experimental result shows that the root system vigor of uniconazole P microemulsion seed soaking the raising significantly wheat seedling promotes root elongation, and lateral root increases.The growth that healthy and strong flourishing root system is an acrial part is laid a good foundation, and can improve the absorb efficient of root to moisture and nutrient component.Can find out that from table 3 data during the seed soaking of 1.0mg/L concentration microemulsion, the contrast of fresh weight root/shoot ratio wetting powder has increased by 3.70%, has increased by 40.77% than the clear water contrast.Further specify uniconazole P microemulsion seed soaking and can cultivate wheat strong sprout.Concrete experimental data is seen table 3.
Table 3 is the average fresh weight of wheat in the time of the 14th day
3. to the influence of wheat dry-matter accumulation
Specific leaf weight is to weigh a parameter of leaf photosynthesis performance, and the little respiration consumption of leaf area is few; Specific leaf weight is high, and leaf photosynthesis is strong, helps the accumulation of dry matter.Experimental studies results shows that leaf dry weight and specific leaf weight have increased by 1.18% and 1.80% than the wetting powder contrast respectively during the seed soaking of 1.0mg/L concentration microemulsion, has increased by 23.74% and 73.37% than the clear water contrast; Acrial part dry weight and under ground portion dry weight have increased by 5.35% and 7.65% than the wetting powder contrast respectively, have increased by 34.05% and 51.24% than the clear water contrast; The dry weight root/shoot ratio has increased by 2.17% than the wetting powder contrast, has increased by 12.82% than the clear water contrast, explains that the seed soaking of uniconazole P microemulsion has very big potentiality on enhancing wheat resistance.
Embodiment 4
Uniconazole P microemulsion provided by the invention is diluted to concentration 0.25mg/L, 0.5mg/L, 1.0mg/L, 2.0mg/L acts on the mung bean seedling.
1. to the influence of mung bean germination vigor and germination rate
Cultivate the mung bean seedling under the same environmental conditions, experimental result shows that germination vigor has increased by 4.55% than the wetting powder contrast during seed soaking of 1.0mg/L microemulsion, has reduced 5.56% than the clear water contrast.The germination rate of four kinds of concentration equates to be 100%.This shows that uniconazole P microemulsion seed soaking mung bean is down germinateed neat.
2. to the influence of mung bean seedlings form
Test equally to the 14th day, when concentration was soaked seed for the 1.0mg/L microemulsion, height of seedling had reduced by 13.91% than the wetting powder contrast, had reduced by 82.07% than the clear water contrast; Root is long and stem foot is wide has increased by 15.95% and 8.39% than the wetting powder contrast respectively, has increased by 136.45% and 106.67% than the clear water contrast; The fresh weight root/shoot ratio has increased by 14.75% than the wetting powder contrast, has increased by 114.83% than the clear water contrast.This shows that uniconazole P microemulsion seed soaking can cultivate mung bean strong sprout.
3. to the influence of mung bean dry-matter accumulation
The mung bean blade of microemulsion seed soaking is shorter, and leaf area is less.Experiment inspection result shows, leaf dry weight had increased by 3.68% and 13.79% than the wetting powder contrast respectively with specific leaf weight when concentration was the microemulsion seed soaking of 1.0mg/L, and contrasting than clear water has increased by 11.90% and 50.51%; Acrial part dry weight and under ground portion dry weight have increased by 0.49% and 15.49% than the wetting powder contrast respectively, have increased by 9.95% and 102.47% than the clear water contrast; The dry weight root/shoot ratio has increased by 14.92% than the wetting powder contrast, has increased by 84.09% than the clear water contrast, explains that the uniconazole P seed soaking has very big potentiality equally on enhancing mung bean resistance.
Claims (4)
1. uniconazole P microemulsion, form by following component by mass percentage:
Said solvent is one or more the combination in aromatic hydrocarbons, alcohols, ketone, ester class or the polar solvent;
Said surfactant is one or more the combination among dodecyl sodium sulfate, Tween-80, Tween-60, AEO-9, the OP-10;
Said cosurfactant is a kind of in methyl alcohol, ethanol, isopropyl alcohol, n-butanol, the n-amyl alcohol;
Said antifreeze is an ethylene glycol;
Said water is a kind of in deionized water, standard hard water or the running water.
2. uniconazole P microemulsion according to claim 1; It is characterized in that: said solvent is benzene,toluene,xylene, methyl alcohol, ethanol, n-butanol, acetone, cyclohexanone, N, the combination of one or more in dinethylformamide, dimethyl sulfoxide (DMSO), the ethyl acetate.
3. the preparation method of uniconazole P microemulsion; Uniconazole P is fully mixed with solvent, surfactant, cosurfactant and antifreeze in proportion, under agitation slowly add entry, in 40 ℃ of following heated and stirred 30min; System changes into the O/W type by w/o type, and the room temperature cooling promptly gets.
4. the application of uniconazole P microemulsion in wheat and the regulation and control of mung bean seedling early growth according to claim 1.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105145603A (en) * | 2015-08-14 | 2015-12-16 | 蔡家锟 | Composite wheat seed soaking agent as well as preparation method, usage method and application thereof |
| CN106905037A (en) * | 2017-02-24 | 2017-06-30 | 黑龙江八农垦大学 | A kind of interacting composition for preventing the lodging of mung bean middle and later periods and improving the foliar spray conditioning agent and nutrient of yield |
| CN107361059A (en) * | 2017-08-14 | 2017-11-21 | 四川省兰月科技有限公司 | Microemulsion containing amino-oligosaccharide and uniconazole P |
| CN114097774A (en) * | 2021-11-20 | 2022-03-01 | 武汉船用电力推进装置研究所（中国船舶重工集团公司第七一二研究所） | Preparation method of mesoporous silica nano double-layer microsphere controlled release agent |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105145603A (en) * | 2015-08-14 | 2015-12-16 | 蔡家锟 | Composite wheat seed soaking agent as well as preparation method, usage method and application thereof |
| CN106905037A (en) * | 2017-02-24 | 2017-06-30 | 黑龙江八农垦大学 | A kind of interacting composition for preventing the lodging of mung bean middle and later periods and improving the foliar spray conditioning agent and nutrient of yield |
| CN107361059A (en) * | 2017-08-14 | 2017-11-21 | 四川省兰月科技有限公司 | Microemulsion containing amino-oligosaccharide and uniconazole P |
| CN114097774A (en) * | 2021-11-20 | 2022-03-01 | 武汉船用电力推进装置研究所（中国船舶重工集团公司第七一二研究所） | Preparation method of mesoporous silica nano double-layer microsphere controlled release agent |
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