CN102365287A - 蓝月季中含有的新型化合物 - Google Patents
蓝月季中含有的新型化合物 Download PDFInfo
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- CN102365287A CN102365287A CN2010800139531A CN201080013953A CN102365287A CN 102365287 A CN102365287 A CN 102365287A CN 2010800139531 A CN2010800139531 A CN 2010800139531A CN 201080013953 A CN201080013953 A CN 201080013953A CN 102365287 A CN102365287 A CN 102365287A
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| JP2009-115722 | 2009-05-12 | ||
| JP2009115722 | 2009-05-12 | ||
| JP2009-173096 | 2009-07-24 | ||
| JP2009173096 | 2009-07-24 | ||
| PCT/JP2010/055262 WO2010110382A1 (ja) | 2009-03-27 | 2010-03-25 | 青いバラに含まれる新規化合物 |
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| CN102365287A true CN102365287A (zh) | 2012-02-29 |
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| CN2010800139531A Pending CN102365287A (zh) | 2009-03-27 | 2010-03-25 | 蓝月季中含有的新型化合物 |
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| EP (2) | EP2947083A1 (https=) |
| JP (3) | JP5099653B2 (https=) |
| KR (1) | KR101659525B1 (https=) |
| CN (1) | CN102365287A (https=) |
| AU (1) | AU2010228224B2 (https=) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106456492A (zh) * | 2014-05-19 | 2017-02-22 | 三得利控股株式会社 | 蔷薇色素化合物的新型用途 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3950067A1 (en) | 2019-03-29 | 2022-02-09 | Suntory Holdings Limited | Ltbp-1 expression promoting composition and method for screening for substance having ltbp-1 expression promoting function |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993001290A1 (en) * | 1991-07-11 | 1993-01-21 | International Flower Developments Pty. Ltd. | Genetic sequences encoding flavonoid pathway enzymes and uses therefor |
| JPH05184370A (ja) * | 1992-01-14 | 1993-07-27 | Kirin Brewery Co Ltd | フラボノイド水酸化酵素遺伝子 |
| WO1996036716A1 (en) * | 1995-05-16 | 1996-11-21 | International Flower Developments Pty. Ltd. | Transgenic plants exhibiting altered flower colour and methods for producing same |
| JP2002201372A (ja) * | 2000-09-29 | 2002-07-19 | Suntory Ltd | 植物色素化合物及びその利用 |
| CN1678746A (zh) * | 2002-08-30 | 2005-10-05 | 国际花卉开发有限公司 | 类黄酮3’,5’羟化酶基因序列及其用途 |
| EP1652916A1 (en) * | 2003-08-13 | 2006-05-03 | INTERNATIONAL FLOWER DEVELOPMENTS Proprietary Limited | Process for producing rose with modified color |
| WO2008156214A1 (ja) * | 2007-06-20 | 2008-12-24 | International Flower Developments Proprietary Limited | フラボン及びデルフィニジンを含むバラ及びその生産方法 |
| WO2008156206A1 (ja) * | 2007-06-20 | 2008-12-24 | International Flower Developments Proprietary Limited | フラボン及びマルビジンを含むバラ及びその生産方法 |
| WO2008156211A1 (ja) * | 2007-06-20 | 2008-12-24 | International Flower Developments Proprietary Limited | フラボンを含むバラ及びその生産方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0970290A (ja) | 1995-02-17 | 1997-03-18 | Suntory Ltd | アシル基転移活性を有する蛋白質をコードする遺伝子 |
| JP5241012B2 (ja) * | 2005-07-15 | 2013-07-17 | ノバルティス アーゲー | Ｐａｍｐｓ、病原体関連分子パターン |
| JP5285304B2 (ja) * | 2007-03-15 | 2013-09-11 | 石原産業株式会社 | ツユクサのフラボノイド３’，５’−水酸化酵素遺伝子 |
| TW200845888A (en) | 2007-03-29 | 2008-12-01 | Int Flower Dev Pty Ltd | Process for generation of surface chimera transgenic plants |
-
2010
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- 2010-03-25 CA CA2756087A patent/CA2756087C/en active Active
- 2010-03-25 MX MX2011009991A patent/MX2011009991A/es active IP Right Grant
- 2010-03-25 WO PCT/JP2010/055262 patent/WO2010110382A1/ja not_active Ceased
- 2010-03-25 EP EP10756178A patent/EP2412715A4/en not_active Withdrawn
- 2010-03-25 BR BRPI1009803A patent/BRPI1009803A8/pt not_active Application Discontinuation
- 2010-03-25 CN CN2010800139531A patent/CN102365287A/zh active Pending
- 2010-03-25 KR KR1020117022593A patent/KR101659525B1/ko active Active
- 2010-03-25 US US13/259,749 patent/US9057076B2/en active Active
- 2010-03-25 AU AU2010228224A patent/AU2010228224B2/en active Active
- 2010-03-25 RU RU2011143378/04A patent/RU2507206C2/ru active
- 2010-03-25 JP JP2011506120A patent/JP5099653B2/ja active Active
- 2010-03-26 TW TW099109119A patent/TWI493033B/zh active
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2011
- 2011-09-25 IL IL215359A patent/IL215359A0/en unknown
- 2011-09-27 EC EC2011011356A patent/ECSP11011356A/es unknown
- 2011-09-27 CO CO11126046A patent/CO6430465A2/es active IP Right Grant
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2012
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2014
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Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993001290A1 (en) * | 1991-07-11 | 1993-01-21 | International Flower Developments Pty. Ltd. | Genetic sequences encoding flavonoid pathway enzymes and uses therefor |
| JPH05184370A (ja) * | 1992-01-14 | 1993-07-27 | Kirin Brewery Co Ltd | フラボノイド水酸化酵素遺伝子 |
| WO1996036716A1 (en) * | 1995-05-16 | 1996-11-21 | International Flower Developments Pty. Ltd. | Transgenic plants exhibiting altered flower colour and methods for producing same |
| JP2002201372A (ja) * | 2000-09-29 | 2002-07-19 | Suntory Ltd | 植物色素化合物及びその利用 |
| CN1678746A (zh) * | 2002-08-30 | 2005-10-05 | 国际花卉开发有限公司 | 类黄酮3’,5’羟化酶基因序列及其用途 |
| EP1652916A1 (en) * | 2003-08-13 | 2006-05-03 | INTERNATIONAL FLOWER DEVELOPMENTS Proprietary Limited | Process for producing rose with modified color |
| WO2008156214A1 (ja) * | 2007-06-20 | 2008-12-24 | International Flower Developments Proprietary Limited | フラボン及びデルフィニジンを含むバラ及びその生産方法 |
| WO2008156206A1 (ja) * | 2007-06-20 | 2008-12-24 | International Flower Developments Proprietary Limited | フラボン及びマルビジンを含むバラ及びその生産方法 |
| WO2008156211A1 (ja) * | 2007-06-20 | 2008-12-24 | International Flower Developments Proprietary Limited | フラボンを含むバラ及びその生産方法 |
Non-Patent Citations (3)
| Title |
|---|
| HOLTON等: "Blue roses- a pigment of our imagination?", 《TRENDS IN BIOTECHNOLOGY》, vol. 12, 31 December 1994 (1994-12-31), pages 40 - 42, XP023595397, DOI: doi:10.1016/0167-7799(94)90097-3 * |
| YUKO FUKUI等: "Structure of rosacyanin B, a novel pigment from the petals of Rosa hybrida", 《TETRAHEDRONLETTERS》, vol. 43, 31 December 2002 (2002-12-31), pages 2637 - 2639, XP004343971, DOI: doi:10.1016/S0040-4039(02)00305-2 * |
| YUKO FUKUI等: "Two novel blue pigments with ellagitannin moiety, rosacyanins A1 and A2, isolated from the petals of Rosa hybrida", 《TETRAHEDRON》, vol. 62, 31 December 2006 (2006-12-31), pages 9661 - 9670 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106456492A (zh) * | 2014-05-19 | 2017-02-22 | 三得利控股株式会社 | 蔷薇色素化合物的新型用途 |
| CN106456492B (zh) * | 2014-05-19 | 2019-09-24 | 三得利控股株式会社 | 蔷薇色素化合物的用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| US9057076B2 (en) | 2015-06-16 |
| RU2011143378A (ru) | 2013-05-10 |
| BRPI1009803A2 (pt) | 2015-08-25 |
| KR101659525B1 (ko) | 2016-09-23 |
| JP2013014589A (ja) | 2013-01-24 |
| EP2412715A4 (en) | 2012-09-26 |
| AU2010228224A1 (en) | 2011-10-13 |
| EP2412715A1 (en) | 2012-02-01 |
| TW201038736A (en) | 2010-11-01 |
| CO6430465A2 (es) | 2012-04-30 |
| CA2756087A1 (en) | 2010-09-30 |
| ECSP11011356A (es) | 2011-11-30 |
| JP5099653B2 (ja) | 2012-12-19 |
| CA2756087C (en) | 2017-04-18 |
| IL215359A0 (en) | 2011-12-29 |
| JP2014210786A (ja) | 2014-11-13 |
| EP2947083A1 (en) | 2015-11-25 |
| TWI493033B (zh) | 2015-07-21 |
| JPWO2010110382A1 (ja) | 2012-10-04 |
| MX2011009991A (es) | 2011-12-08 |
| JP5766334B2 (ja) | 2015-08-19 |
| JP5569822B2 (ja) | 2014-08-13 |
| RU2507206C2 (ru) | 2014-02-20 |
| BRPI1009803A8 (pt) | 2017-02-14 |
| WO2010110382A1 (ja) | 2010-09-30 |
| KR20120018741A (ko) | 2012-03-05 |
| AU2010228224B2 (en) | 2015-09-17 |
| US20120011771A1 (en) | 2012-01-19 |
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