CN102357208B - Traditional Chinese medicine composition for treating diabetes, hyperglycemia, hypertension, and hyperlipidemia - Google Patents

Traditional Chinese medicine composition for treating diabetes, hyperglycemia, hypertension, and hyperlipidemia Download PDF

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CN102357208B
CN102357208B CN2011103470842A CN201110347084A CN102357208B CN 102357208 B CN102357208 B CN 102357208B CN 2011103470842 A CN2011103470842 A CN 2011103470842A CN 201110347084 A CN201110347084 A CN 201110347084A CN 102357208 B CN102357208 B CN 102357208B
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weight portions
ganoderma
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medicine composition
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CN102357208A (en
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张正高
钱一帆
张林湄
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ANHUI HUANGSHAN YUNLE GLOSSY GANODERMA Co Ltd
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ANHUI HUANGSHAN YUNLE GLOSSY GANODERMA Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine composition for treating diabetes, hyperglycemia, hypertension, and hyperlipidemia; the traditional Chinese medicine composition is prepared by ganoderma lucidum, ganoderma atrum, ganoderma applanatum, trametes versicolor extract, sporoderm-broken ganoderma lucidum spore powder, polygonum multiflorum extract, rhizoma gastrodiae extract, poria cocos extract, ginkgo extract, dark plum extract, kudzu root extract, Tibet rhodiola rosea extract, and pine needle extract. The composition can effectively treat, improve or prevent diseases of diabetes, hyperlipidemia, hypertension, and hyperglycemia, and is applicable to various populations with body essence, energy and spirit unbalance, fatiguability, dietary nutrition unbalance, and the three-high symptom of diabetes caused by multiple reasons such as rapid working and life rhythm, much electromagnetic radiation, much environmental pollution, greasy and acidic diet and the like for modern people.

Description

A kind of Chinese medicine composition for the treatment of diabetes, hyperglycemia, hypertension, hyperlipidemia
Technical field
The invention belongs to the field of Chinese medicines, relate to the Chinese medicine composition of the treatment of a kind of medicine-food two-purpose and health care, be specifically related to a kind of treat improvement or prevent diabetes, hypertension, hyperlipidemia disease Chinese medicine composition.
Background technology
Ganoderma is the sporophore of basidiomycetes Polyporaceae Ganoderma plant Ganoderma or Ganoderma, GUYAO ancient books and records (Shennong's Herbal and Compendium of Material Medica) record:
" Ganoderma lucidum (Leyss. Ex Fr.) Karst. (Ganoderma lucisum): the abnormal smells from the patient hardship, flat; Nontoxic.Control pent-up in the heart, the beneficial motive, invigorating middle warmer increases wisdom, and hypermnesia is recalled.Food is made light of one's life by commiting suicide and is prolonged life for a long time." " Fructificatio Amaurodermatis Rudae (profound sesame): abnormal smells from the patient is salty, and is flat; Nontoxic.Control epilepsy, dredging water passages, kidney tonifying gas, logical nine orifices, audition improvement order.Food is made light of one's life by commiting suicide and is prolonged life for a long time.”
Li Shizhen (1518-1593 A.D.) Compendium of Material Medica and " the former colour identification collection of illustrative plates of Chinese medicine " No. the 053471st, Chinese depository library CIP data core word (2004) (<Wang Shengmin, Song Xiaomei, Xueyuan Press, Zhang Ying chief editor-Beijing 2004 〉) and " Chinese medicine voluminous dictionary ", " Chinese pharmacopoeia is recorded: " Ganoderma lucidum (Leyss. Ex Fr.) Karst.: property is put down, sweet in the mouth.Replenishing QI and blood, tranquilizing mind, strengthening the spleen and stomach." " Ganoderma applanatum (pers) pat: property is flat, mildly bitter flavor.Anti-inflammatory and anticancer." " Coriolous Dersicolor (Fr.) Quel: cold nature, slightly sweet flavor.The Li Wen that is good for the stomach, relieving cough and asthma, heat-clearing and toxic substances removing, antitumor, anti-hepatitis virus.”
The present invention is based on the individual character and the general character effect of the Ganoderma class pharmacological action of different cultivars in classic nationality and the modern authoritative ancient books and records theory, and with certain pharmacology individual character and the general character effects of each tool such as the Radix Polygoni Multiflori of medicine-food two-purpose, Rhizoma Gastrodiae, Poria, Semen Ginkgo, Fructus Mume, Radix Puerariae, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu, pine needle, with above-mentioned medical material be mixed with out can effectively treat improvement or prevent diabetes, hyperglycemia, hypertension, hyperlipidemia Chinese medicine composition.
Summary of the invention
It is main component based on red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat., Coriolus Versicolor P.E., Ganoderma spore powder with cellular wall broken that technical problem solved by the invention is to provide a kind of, be aided with Radix Polygoni Multiflori extract, Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract, pine needle extract, be mixed with out the Chinese medicine composition of the Ganoderma prescription that can treat improvement or prevent diabetes, hyperglycemia, hypertension, hyperlipidemia.
The objective of the invention is to realize in the following manner:
A kind of Chinese medicine composition for the treatment of diabetes, hyperglycemia, hypertension, hyperlipidemia, make by the component of following weight portion:
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 8~20 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 8~20 weight portions;
Ganoderma spore powder with cellular wall broken 8~20 weight portions;
Radix Polygoni Multiflori extract 4~8 weight portions;
Rhizoma Gastrodiae extract 4~8 weight portions;
Poria extract 5~10 weight portions;
Semen Ginkgo extrac 4~8 weight portions;
Fructus Mume extract 7~15 weight portions;
Radix Puerariae extract 5~12 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 5~10 weight portions;
Pine needle extract 5~10 weight portions.
The Chinese medicine composition of above-mentioned treatment diabetes, hyperglycemia, hypertension, hyperlipidemia is preferably made by the component of following weight portion:
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 8~15 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 8~15 weight portions;
Ganoderma spore powder with cellular wall broken 8~15 weight portions;
Radix Polygoni Multiflori extract 4~6 weight portions;
Rhizoma Gastrodiae extract 4~6 weight portions;
Poria extract 6~8 weight portions;
Semen Ginkgo extrac 4~6 weight portions;
Fructus Mume extract 8~10 weight portions;
Radix Puerariae extract 6~8 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 5~8 weight portions;
Pine needle extract 5~8 weight portions.
The Chinese medicine composition of above-mentioned treatment diabetes, hyperglycemia, hypertension, hyperlipidemia, most preferably make by the component of following weight portion:
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 10 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 10 weight portions;
Ganoderma spore powder with cellular wall broken 10 weight portions;
Radix Polygoni Multiflori extract 5 weight portions;
Rhizoma Gastrodiae extract 5.5 weight portions;
Poria extract 7 weight portions;
Semen Ginkgo extrac 4.5 weight portions;
Fructus Mume extract 9 weight portions;
Radix Puerariae extract 7 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 6 weight portions;
Pine needle extract 6 weight portions.
The present invention can be with red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat., Coriolus Versicolor P.E., Ganoderma spore powder with cellular wall broken, Radix Polygoni Multiflori extract, Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract and pine needle extract directly are mixed and made into powder or add the pharmacy acceptable auxiliary makes oral formulations.Described oral formulations is preferably capsule, tablet, granule or pill.
The preparation method of aforementioned pharmaceutical compositions comprises red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat. (preferably adopting wild red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat.), Coriolus Versicolor P.E., Ganoderma spore powder with cellular wall broken (sporoderm-broken rate is preferred more than 85%), Radix Polygoni Multiflori extract (preferably adopting wild Radix Polygoni Multiflori), Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract and pine needle extract mix evenly, pulverizing, preparation.
Coriolus Versicolor P.E., Radix Polygoni Multiflori extract, Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract and pine needle are got thing and are crude drug and add medical material 8-12 times of water gaging heating extraction 2-3 time respectively, each 1-3 hour, filter, merging filtrate, filtrate concentrates, dry and get.Each extract all should be dry, evenly, do not have caking, no adhesion, and nothing is gone mouldy.
In the side, the general character of the therapeuticing and health effect of " five sesames " red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat., Coriolous Dersicolor (Fr.) Quel and Ganoderma spore powder with cellular wall broken is: " flat, nontoxic, the of a specified duration food of nature and flavor is made light of one's life by commiting suicide and prolonged life "; Contain fungus polysaccharide and triterpenic acid, adenosine, organic selenium, germanium, several mineral materials, trace element zinc, potassium, calcium, magnesium, multiple natural complex; Can control the division differentiation of cell, it is old and feeble to regulate the cell growth; The effect that has human body immunity improving power, impels cancerous cell to become feeble and die; Can two-ways regulation, from whole, from the basic body vital organs of the human body, the extremity bones of the body collectively regulated comprehensively to being in harmonious proportion balance health; " with hundred medicines " simultaneously, can take simultaneously with any food medicine and do not avoid anti-; " preventive treatment of disease " has no side effect; Can reduce the many diseases that cause because of hypoimmunity, as flu, hepatitis etc.; Blood sugar lowering, fall that blood is glutinous, blood fat reducing, the high hypotension of adjusting, protecting liver and detoxication; Radioprotective, anti-nuisance are poisoned; Nourish skin, defying age; Suppress tumor growth, suppress gastric ulcer and ulcer class disease; Calm the nerves, treat the neurasthenia; Treatment chronic bronchitis, bronchial asthma.The Ganoderma spore powder with cellular wall broken sporoderm-broken rate that adopts should be the elite of Ganoderma greater than 85%, and its active constituent content and treatment, improvement or prevention effects are the several times of Ganoderma body even more than 10 times, more can strengthen consolidating the power of five sesames.The therapeuticing and health effect of five kinds of Ganodermas respectively has its more outstanding individual character that more stresses again simultaneously.
Red ganoderma, Ganoderma lucidum (Leyss. Ex Fr.) Karst. has another name called " refreshing hut Ganoderma lucidum (Leyss. Ex Fr.) Karst. " and is commonly called as " Ganoderma lucidum seu Japonicum ", and genus polyporus Cordycepps class (Polyporaceae), medicinal and edible plant meet 2010 editions regulations of Pharmacopoeia of People's Republic of China.Cure mainly pent-up in the heart, the beneficial motive, hypermnesia is recalled, and promptly stresses " the heart and brain people having the same aspiration and interest "; Fructificatio Amaurodermatis Rudae is called profound sesame, black clouds sesame, false Ganoderma, Latin Fructificatio Amaurodermatis Rudae by name or Fructificatio Amaurodermatis Rugosi.Dredging water passages, kidney tonifying gas promptly stresses " medical treatment kidney "; Gan-oderma applanatum (Pers.Ex Wallr) Pat.: latin name: Gan-oderma applanatum (Pers.Ex Wallr) Pat. is the herb of fungi plant medicine Polyporaceae plant Ganoderma applanatum (Pers. Ex Wallr) Pat..Another name: redness of the skin or complexion one's old mother bacterium (" Chinese medicinal fungi "), Ganoderma applanatum (Pers.)Pat., flat sesame (Jiangsu), flat gill fungus, the rotten bacterium of white macula, Fructus Gleditsia bacterium (Sichuan)." anti-inflammatory and anticancer " is for stressing; Coriolous Dersicolor (Fr.) Quel: the dampness removing that is good for the stomach, heat-clearing and toxic substances removing, antitumor, anti-hepatitis virus, promptly " prevent and treat hepatitis B infected and hepatitis B cancerate " is to stress.
Radix Polygoni Multiflori: nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria dispels the wind, detoxifcation.Invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening.Blood fat reducing, blood sugar lowering, strengthening the spleen and stomach, fill blood.Rhizoma Gastrodiae: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Treatment headache, dizzy, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.Blood pressure lowering, antiinflammatory, enhance immunity.Poria: diuresis, tranquillizing and allaying excitement, spleen invigorating, protect the liver.Cure for insomnia, gastric ulcer, edema oliguria.Semen Ginkgo: strengthen elasticity of blood vessels, increase cerebrocardiac blood flow, reduce the viscosity of blood, prevent thrombosis, improve brain function and prevent and treat alzheimer disease.Improve moderate cognitive disorder, hypomnesis, the hypophrenia, prevention of stroke, the rehabilitation of apoplexy sequela is also had certain effect.Blood circulation promoting and blood stasis dispelling, control cardiovascular and cerebrovascular disease, defying age.Fructus Mume: natural disease-resistant bacterium, antiinflammatory, treatment chronic digestible road inflammation, colitis, cholecystitis are cleared up oils and fats and acidic materials in the food.Radix Puerariae: contain compositions such as daidzein, daiazi, Radix Puerariae phenol, Radix Puerariae glycosides, triterpene saponin, isoflavone, organic selenium.The heart and brain people having the same aspiration and interest reaches upper orifices thoroughly; The motionless blood of invigorating blood circulation promotes the production of body fluid and moistens blood; Blood circulation and channel invigorating and the merit of emergency is arranged can be alleviated the disease of heart and brain blood vessels spasm, strong urgency.Resist myocardial ischemia, pharmacological action such as arrhythmia, blood vessel dilating, microcirculation improvement, reduction myocardial oxygen consumption, resisting hypertension, antiplatelet aggregation, blood sugar lowering, blood fat reducing, analgesic, spasmolytic, Fructus Alpiniae Oxyphyllae, antitumor, anti-hypoxia, antioxidation, detoxifcation.Isoflavone in the Radix Puerariae etc. have relieving spasm to stop pain, strengthen brain and crown blood flow volume, strengthen myocardial contraction, the effects such as immunity of control nervous headache, antioxidation and enhancing body.Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu (Rhodiola tibetica (Hook.f.et Thoms.) S.H.Fu): tranquilizing by nourishing the heart, blood circulation promoting and blood stasis dispelling, hemostasis, heat-clearing and toxic substances removing.Can improve cardiac and cerebral blood-supply, the vexed cardiopalmus of brain, arrhythmia and angina pectoris that treatment coronary heart disease produces.
Pine needle: pinaster formal name used at school Pinus, belong to the Pinaceae Pinus, come up, after cotyledon launches, at first what give birth to is acrospire, Dan Sheng, helical arrangement, wire lanceolar, leaf margin tool tooth.Acrospire was exercised the function of leaf after 1~3 year, needle occurred.Pine needle contains beneficiating ingredients such as Colophonium, pine needle verdazulene, pine-needle amino-acid, pine proanthocyanidin, Folium Pini beta-carotene, pine needle flavone.Function cures mainly: the resurrection and the new life that remove impurity in the blood vessel, reduction blood viscosity, treatment apoplexy sequela, short brain blood circulation improvement and brain cell.
Chinese medicine composition of the present invention can be used in health food for preparing treatment, improvement or prevent diabetes, hypertension, hyperglycemia, hyperlipidemia or medicine.Health food can be the health food of complementary diets nutrition.
With the present composition according to anxious poison and long poison experimental period to the mouse stomach administration, movable normal after the administration, do not find mice on the feed, aspects such as breathing, heart rate, chroma of hair unusual, none is only dead for mice.
Combination principle: five kinds of Ganodermas that the present invention selects for use are " monarch " with the general character of " nature and flavor are flat, nontoxic, and food is made light of one's life by commiting suicide and prolonged life for a long time ", " raising immunity ", " vital base and primordial QI consolidating ", " waiting until balance fundamentally to regulate the body vital organs of the human body, QI and blood, acid-base value, negative and positive, extremity bones of the body collectively on the whole ", " preventive treatment of disease ".Be aided with integration of edible and medicinal herbs, food and medicament dual-purpose, the effect of medicine arranged and for a long time the Radix Polygoni Multiflori of the toxic and side effects of the no medicine of food, Rhizoma Gastrodiae, Poria, Semen Ginkgo, Fructus Mume, Radix Puerariae, Radix Rhodiolae, pine needle are " minister, help, make ".To the direct targeting performance of existing disease treatment, improvement, inhibitory action.And each complementation that has in five kinds of Ganodermas, with sick different medicine control, the auxiliary effect of adjusting the vital organs of the human body also is " minister ".
The beneficial effect of the present composition compared with the prior art: the present composition echos " monarch ", " treating the same disease with different methods " of Chinese medicine preparation theory, the principle of " preventive treatment of disease ", give full play to pharmacological action separately, effectively treat improvement or prevent diabetes, hyperlipidemia, hypertension, hyperglycemia disease.Be applicable to work the modern rhythm of life be fast, electromagnetic radiation is many, environmental pollution is many, diet oils and fats, acid many reasons such as many cause body " essence, gas, god " unbalance, fatigable many, the unbalance obesity of diet nutritional is many, more than glycosuria " three-hypers " disease and day by day rejuvenation is many, and need anti-electromagnetic-radiation, antipollution, clear up in the meals food and drink too much oils and fats and acidic materials, numerous colonies of balanced diet nutrition, meet modern's pursuit and improve the quality of living, pay attention to the theory of healthy way of keeping good health.
The specific embodiment
For technological means and the effect that the present invention is realized is easy to understand,, further set forth the present invention below in conjunction with specific embodiment.
Embodiment 1
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 10 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 10 weight portions;
Ganoderma spore powder with cellular wall broken 10 weight portions;
Radix Polygoni Multiflori extract 5 weight portions;
Rhizoma Gastrodiae extract 5.5 weight portions;
Poria extract 7 weight portions;
Semen Ginkgo extrac 4.5 weight portions;
Fructus Mume extract 9 weight portions;
Radix Puerariae extract 7 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 6 weight portions;
Pine needle extract 6 weight portions.
Above-mentioned preparation method of extract is respectively crude drug to be added 10 times of water gaging heating extraction 3 times, each 2 hours, filter, and merge 3 times filtrate, filtrate concentrates, drying.Each extract is pulverized the back be mixed and made into powder with Ganoderma spore powder with cellular wall broken.
Embodiment 2
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 20 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 20 weight portions;
Ganoderma spore powder with cellular wall broken 20 weight portions;
Radix Polygoni Multiflori extract 4 weight portions;
Rhizoma Gastrodiae extract 4 weight portions;
Poria extract 10 weight portions;
Semen Ginkgo extrac 8 weight portions;
Fructus Mume extract 15 weight portions;
Radix Puerariae extract 12 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 10 weight portions;
Pine needle extract 10 weight portions.
Above-mentioned preparation method of extract is respectively crude drug to be added 12 times of water gaging heating extraction 2 times, each 3 hours, filter, and merge 2 times filtrate, filtrate concentrates, drying.The conventional adjuvant of adding tablet is mixed in each extract pulverizing back make tablet with Ganoderma spore powder with cellular wall broken.
Embodiment 3
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 8 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 8 weight portions;
Ganoderma spore powder with cellular wall broken 15 weight portions;
Radix Polygoni Multiflori extract 6 weight portions;
Rhizoma Gastrodiae extract 6 weight portions;
Poria extract 8 weight portions;
Semen Ginkgo extrac 4 weight portions;
Fructus Mume extract 8 weight portions;
Radix Puerariae extract 6 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 5 weight portions;
Pine needle extract 8 weight portions.
Above-mentioned preparation method of extract is respectively crude drug to be added 8 times of water gaging heating extraction 3 times, each 2 hours, filter, and merge 3 times filtrate, filtrate concentrates, drying.The conventional adjuvant of adding capsule is mixed in each extract pulverizing back make capsule with Ganoderma spore powder with cellular wall broken.
4 couples of the present invention of embodiment carry out clinical model case experimentation, and the patient suffered from diabetes 4 years, and it is clear and definite once to do the oral glucose tolerance test diagnosis.Previously treat with Chinese and western drugs such as insoral, YUQUAN WAN, LIUWEI DIHUANG WAN etc., but the state of an illness do not feel any better, patient feels misery very much always.In in June, 2008 to patient's trial edition invention prescription, other medicines such as preceding.After adhering to four months, patient's diabetes and other symptom all have improvement.Diabetes check, glucose in urine are repeatedly negative, and blood glucose is normal.At present, this patient's spirit is healthy and vigorous, and body constitution also has obvious enhancing, and withdraws hypoglycemic medicine, and open diet has recovered orthobiosis.
5 couples of the present invention of embodiment carry out clinical model case experimentation, patient 48 years old, and between 9~10, health is fat partially, and is tired with dizziness always for fasting glucose, the puckery blurring of vision of eye, waist knee hyperplasia, abdominal distention uncomfortable in chest, hyperhidrosis are hard and dry, thirsty polydipsia.The higher shakiness of blood pressure pressure reduction.The course of disease 8 years is always by orally-taken blood sugar reducing reducing blood pressure and blood fat medicine and health product control.Bring into use prescription of the present invention in October, 2007, took 3 months, and all diseases alleviate, and surveying the result is fasting glucose 5.5, vision is clearly better, and oral other medicines are stopped not bitterly in the joint, after taking 6 months, blood glucose is about 4, and original other disease such as blood fat and blood pressure disappears substantially.
6 couples of the present invention of embodiment carry out clinical model case experimentation, and patient doctor suffers from surplus the hypertension ten year, dizziness, giddy, the time repeated nauseas, mouthful vomiting watery fluid, obesity, edema of lower limbs, nocturia, moving then asthma, abundant expectoration, aversion to cold and cold limbs, the diet happiness is hot.Blood pressure 210/123mmHg.After using prescription of the present invention to adhere to one month, the head is clear, and diet increases, and nocturia reduces, and it is warm that limbs are felt, measures blood pressure 144/95mmHg, and near normal, all situations take a favorable turn.
7 couples of the present invention of embodiment carry out clinical model case experimentation, patient male, and 50 years old, be diagnosed as hyperlipidemia from 2006, the treatment of oral fat-reducing medicament, blood fat control is not good, chest occurs in 2007 to feel oppressed, and breathes hard, and is weak.Be sent to local hospital admission, check diagnosis: asthma, uncomfortable in chest, sleep that it is awake to suppress night, dizziness; Check on an empty stomach: TG:2.25mmol, TC:5.82mmol, the electrocardiogram prompting: atrial fibrillation, S-T section V5-6 moves down 0.2mv ", " left chamber cardiac dilatation, left chamber diastolic function is bad for Color Sonography.Cardiac inspection: presystole (PEP) prolongs, left ventricular ejection time (LVET), and PEP/LVET ratio increases.Have a medical check-up: blood pressure 150/90mmHg, jugular vein is full, the apex beat disperse, hear sounds is low blunt, heart rate 92 times/minute, rule is neat, and the apical region of heart is heard and blowing systolic murmur, and two bases of lung are heard and a small amount of wet sound of vomiting sound, 1cm under the liver rib, edema of lower limbs.Pale tongue is dark, white and thin fur, deep-thready pulse.Be diagnosed as cardiomyopathy by the doctor, hyperlipidemia.Fail the medicine of blood vessel dilating, blood fat reducing every day.It is still not good to have treated after 7 days effect, and trial edition invention prescription is after 4 months, sxs such as cardiopalmus, gas are tight, headache, dizziness, edema, and appetite, sleep and muscle power also improve significantly.

Claims (8)

1. Chinese medicine composition for the treatment of diabetes, hyperglycemia, hypertension, hyperlipidemia is characterized in that this Chinese medicine composition made by the component of following weight portion:
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 8~20 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 8~20 weight portions;
Ganoderma spore powder with cellular wall broken 8~20 weight portions;
Radix Polygoni Multiflori extract 4~8 weight portions;
Rhizoma Gastrodiae extract 4~8 weight portions;
Poria extract 5~10 weight portions;
Semen Ginkgo extrac 4~8 weight portions;
Fructus Mume extract 7~15 weight portions;
Radix Puerariae extract 5~12 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 5~10 weight portions;
Pine needle extract 5~10 weight portions;
Wherein, Coriolus Versicolor P.E., Radix Polygoni Multiflori extract, Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract and pine needle are got thing and are crude drug and add medical material 8-12 times of water gaging heating extraction 2-3 time respectively, each 1-3 hour, filter, merging filtrate, filtrate concentrate, dry and get.
2. the Chinese medicine composition of treatment diabetes according to claim 1, hyperglycemia, hypertension, hyperlipidemia, its
Be characterised in that this Chinese medicine composition made by the component of following weight portion:
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 8~15 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 8~15 weight portions;
Ganoderma spore powder with cellular wall broken 8~15 weight portions;
Radix Polygoni Multiflori extract 4~6 weight portions;
Rhizoma Gastrodiae extract 4~6 weight portions;
Poria extract 6~8 weight portions;
Semen Ginkgo extrac 4~6 weight portions;
Fructus Mume extract 8~10 weight portions;
Radix Puerariae extract 6~8 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 5~8 weight portions;
Pine needle extract 5~8 weight portions.
3. the Chinese medicine composition of treatment diabetes according to claim 2, hyperglycemia, hypertension, hyperlipidemia is characterized in that this Chinese medicine composition made by the component of following weight portion:
Red ganoderma, Fructificatio Amaurodermatis Rudae, each 10 weight portion of Gan-oderma applanatum (Pers.Ex Wallr) Pat.;
Coriolus Versicolor P.E. 10 weight portions;
Ganoderma spore powder with cellular wall broken 10 weight portions;
Radix Polygoni Multiflori extract 5 weight portions;
Rhizoma Gastrodiae extract 5.5 weight portions;
Poria extract 7 weight portions;
Semen Ginkgo extrac 4.5 weight portions;
Fructus Mume extract 9 weight portions;
Radix Puerariae extract 7 weight portions;
Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract 6 weight portions;
Pine needle extract 6 weight portions.
4. pharmaceutical composition according to claim 1, it is characterized in that red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat., Coriolus Versicolor P.E., Ganoderma spore powder with cellular wall broken, Radix Polygoni Multiflori extract, Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract and pine needle extract directly are mixed and made into powder or add the pharmacy acceptable auxiliary makes oral formulations.
5. pharmaceutical composition according to claim 4 is characterized in that described oral formulations is capsule, tablet, granule or pill.
6. described preparation of drug combination method of claim 1, it is characterized in that this method comprises red ganoderma, Fructificatio Amaurodermatis Rudae, Gan-oderma applanatum (Pers.Ex Wallr) Pat., Coriolus Versicolor P.E., Ganoderma spore powder with cellular wall broken, Radix Polygoni Multiflori extract, Rhizoma Gastrodiae extract, Poria extract, Semen Ginkgo extrac, Fructus Mume extract, Radix Puerariae extract, Rhodiola tibetica (Hook. f. et Thoms.) S. H. Fu extract and pine needle extract mix evenly, preparation.
7. the described Chinese medicine composition of claim 1 is in preparation treatment, improvement or prevent diabetes, hypertension, hyperglycemia, the health food of hyperlipidemia or the application in the medicine.
8. application according to claim 7 is characterized in that described health food is the health food of complementary diets nutrition.
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CN103690574A (en) * 2013-12-25 2014-04-02 南京中科药业有限公司 Poria-containing traditional Chinese medicine combination for enhancing immunity and preparation method of poria-containing traditional Chinese medicine combination
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