CN102357121A - External medicine for treating onychomycosis - Google Patents

External medicine for treating onychomycosis Download PDF

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Publication number
CN102357121A
CN102357121A CN2011103380827A CN201110338082A CN102357121A CN 102357121 A CN102357121 A CN 102357121A CN 2011103380827 A CN2011103380827 A CN 2011103380827A CN 201110338082 A CN201110338082 A CN 201110338082A CN 102357121 A CN102357121 A CN 102357121A
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Prior art keywords
vinegar
percent
radix
treatment
medicine
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CN2011103380827A
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Chinese (zh)
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姚尧
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Individual
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Individual
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Priority to CN2011103380827A priority Critical patent/CN102357121A/en
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Abstract

The invention discloses an external medicine for treating onychomycosis. The medicine comprises the following components in percentage by weight: 93 to 95 percent of vinegar, 3 to 4 percent of common threewingnut root, 1.8 to 2.5 percent of menispermaceae, 0.1 to 0.3 percent of Chinese gentian and 0.1 to 0.2 percent of tribulus terrestris. The vinegar is preferably prepared by mixing ethylic acid and rice vinegar in a ratio of 1:6, and is heated to be boiled, other raw materials are ground and added into the vinegar in turn, and the mixture is uniformly stirred, fully sterilized, sealed and stored while hot, put in a cool and dry place for 15 to 20 days and can be used. The external medicine is filtered preferably, and is more convenient to use after being packaged. The external medicine has the total effective rate of 100 percent, the cure rate of 92 percent and the relapse rate of 2 percent.

Description

The external used medicine of treatment tinea unguium
Technical field: the present invention is the external used medicine that a kind of people's of treatment trick ash refers to (toe) first, specifically is a kind of smear or the moistening growth ash that is placed on refers to the position of (toe) first, and treatment is eliminated ash and referred to (toe) first and grow new normal finger (toe) first medicine for external use.
Background technology: ash refers to that (toe) first belongs to difficult miscellaneous diseases; Be regardless of the morbidity in season, undesirable, the difficult control of conventional therapy effect, refractory are healed, and primary disease is main with fungus, mycete, bacteria mixed infection mainly; Symptom mainly shows as: fingernail turns white, burnt hair, blackout, mattness, deck distortion; The first face has depression, crackle, makes that finger (toe) first becomes fragile, deliquescing, thickens, comes off, and has a strong impact on patient's life, work and social activity.At present, medicine commonly used need be repaiied first with cutter, and the back medicine-feeding is prone to cause wound, wound surface, hemorrhage in repairing the first process, cause new infection.
Summary of the invention:
The present invention solves the weak point that the traditional treatment ash refers to (toe) first, provides a kind of easy to use, simple and direct for ash refers to (toe) first patient, no pain, no wound surface, and moving knife just can eutherapeutic treatment external used medicine.
The present invention adopts following scheme to realize treating the external used medicine that ash refers to (toe) first, has the solvent of following components by weight and solute two parts formulated:
Vinegar 93%~95%, Radix Tripterygii Wilfordii 3%~4%, Radix Stephaniae Tetrandrae 1.8%~2.5%, Radix Gentianae 0.1%~0.3%, Fructus Tribuli 0.1%~0.2%.Wherein vinegar is solvent, and other compositions are solute.
The present invention treats the external used medicine that ash refers to (toe) first, preferably contains the following composition of weight proportion: vinegar 95%, Radix Tripterygii Wilfordii 3%, Radix Stephaniae Tetrandrae 1.8%, Radix Gentianae 0.1%, Fructus Tribuli 0.1%.Vinegar wherein can be various vinegar, and like rice vinegar, mature vinegar, acetic acid, the weight ratio of preferably being pressed 1: 6 by acetic acid and rice vinegar constitutes.Preferably add the Cortex Dictamni of 1% weight, promptly add the Cortex Dictamni of original raw material gross weight 1% weight.
Pharmacology of the present invention is
1, medical acetic acid can suppress the pathogenic microorganism growth and breeding, but kill bacteria when reaching certain high concentration.
2, rice vinegar is to form through fermented grain, can change the original performance of medicine and enlarge curative effect.
3, Radix Tripterygii Wilfordii, very toxic, can reduce viscosity of the blood, anticoagulant reduces the peripheral blood resistance, and 48 kinds of funguses, antibacterials are had inhibitory action.To pass through process of preparing Chinese medicine detoxification before using, can use.
The untoward reaction of taking: feeling sick can appear in the lighter, vomiting, eczema-like dermatitis, erythra, and minority is seen alopecia, because the present invention is external, above-mentioned reaction can not occur.Can make finger (toe) first attenuation, softening.
4, Radix Stephaniae Tetrandrae: analgesia and antiinflammatory action are arranged, and obviously anticoagulant prevents blood coagulation, promotes fibrinolysis, and extensive anti-allergic effects is arranged.
5, Radix Gentianae can suppress trichophyton gypseum and fungus, and muscle is had relaxation effect.
6, Cortex Dictamni, it is antibacterial to detoxify, and Trichophyton concentricunm, the long pathogenic fungus of ulotrichy microspore's tinea bacterium are had inhibitory action; Have refrigeration function simultaneously, use Cortex Dictamni should not use in right amount more, overdose and cause allergy; Like external atomic allergic phenomena is arranged, recover voluntarily after the drug withdrawal.
7, Fructus Tribuli, slightly poisonous, must detoxify by parching to brown with preceding, Fructus Tribuli can be broken the wei knot and gathered antiallergic, the anaphylaxis of separating Cortex Dictamni at this Fang Zhongke.
Comprehensive above-mentioned pharmacology is learnt from other's strong points to offset one's weaknesses between each medicine, the mutual reinforcement between mutual-assistance, and dissolving cutin, antibacterial, sterilization generate new first.
Treatment ash of the present invention refers to that the dosage form of the medicine of (toe) first can be ointment, is preferably the external soak, forms solute vinegar and soaks the solution that other compositions form.Medication every day spreads upon ash and refers to (toe) first, or the soaking medicated liquid flexible material is placed on ash and refers to that (toe) first soaked 3~4 hours, and the time is long more, and effect is good more.The SM two weeks is a course of treatment, generally needs to cure 2 courses of treatment.Therapeutic effect of the present invention is a total effective rate 100%, cure rate 92%, relapse rate 2%.
The specific embodiment
Embodiment 1, a kind of external used medicine that is used to treat tinea unguium
Press the preparation of formulation components and technology, at first, choose and take by weighing 100 kilograms of required vinegar, Radix Tripterygii Wilfordii, Radix Stephaniae Tetrandrae, Radix Gentianae, Fructus Tribuli raw material, vinegar 93%, Radix Tripterygii Wilfordii 4%, Radix Stephaniae Tetrandrae 2.5%, Radix Gentianae 0.3%, Fructus Tribuli 0.2% on request.Elder generation all pulverizes above-mentioned raw materials subsequent use except vinegar, with the vinegar in the prescription, is placed on the container internal heating to boiling.Add Radix Tripterygii Wilfordii, Radix Stephaniae Tetrandrae, Radix Gentianae, Fructus Tribuli then sequentially respectively, stir while adding, after stirring, fully sterilization is airtight while hot, seals up for safekeeping, puts shady and cool dry place, deposits 15-20 days.After the filtration, in liquid, place the adjuvant of processing ointment, process ointment; Can use after the packing, during treatment ointment is applied on the disease first, every day, ointment remained on disease first position 3~4 hours; Time is long more, and effect is good more, and the SM two weeks is a course of treatment; After 2 courses of treatment, 10 patients cure.
Embodiment 2:
Select prescription by weight for use: vinegar 93%, Radix Tripterygii Wilfordii 4%, Radix Stephaniae Tetrandrae 2.5%, Radix Gentianae 0.3%, Fructus Tribuli 0.2%.With the vinegar in the prescription, be placed on the container internal heating to boiling.Add Radix Tripterygii Wilfordii, Radix Stephaniae Tetrandrae, Radix Gentianae, Fructus Tribuli then sequentially respectively, stir while adding, after stirring, fully sterilization is airtight while hot, seals up for safekeeping, puts shady and cool dry place, deposits 30 days.Filter out the liquid medicinal liquid, can use after the packing.Select for use special adhesive tape, absorbent cotton to be fixed on the disease first during treatment, absorbent cotton drips medicinal liquid, soaks every day 3~4 hours, and the time is long more, and effect is good more, and the SM two weeks is a course of treatment.Treatment tinea unguium 20 examples, total effective rate 100% reaches 90% through two course of therapy cure rates, reaches 95% through three course of therapy cure rates, follows up a case by regular visits to after 1 year of healing and does not have recurrence.
Embodiment 3:
Select prescription for use for 10 kilograms by weight: vinegar 94%, Radix Tripterygii Wilfordii 3.5%, Radix Stephaniae Tetrandrae 2.1%, Radix Gentianae 0.2% Fructus Tribuli 0.2%.The also outer Cortex Dictamni that is added with above-mentioned raw materials gross weight 1%, promptly 0.1 kilogram Cortex Dictamni adds raw material, and elder generation all pulverizes above-mentioned all raw materials subsequent use except vinegar, with the vinegar in the prescription, is placed on the container internal heating to boiling.Add Radix Tripterygii Wilfordii, Radix Stephaniae Tetrandrae, Radix Gentianae, Fructus Tribuli, Cortex Dictamni then sequentially respectively, stir while adding, after stirring, fully sterilization is airtight while hot, seals up for safekeeping, puts shady and cool dry place, deposits 15-20 days.Liquid after the filtration is used to spread upon tinea unguium, and per 15 days is a course of treatment, treatment tinea unguium 18 examples; Total effective rate 100%, through two course of therapy recovery from illness number 17 people, cure rate reaches 94%; Through all treating recovery from illness three courses of treatment, follow up a case by regular visits to after cure rate reaches 100%, one year and do not have recurrence.
Embodiment 4:
Select prescription by weight for use: vinegar 95%, Radix Tripterygii Wilfordii 3%, Radix Stephaniae Tetrandrae 1.8%, Radix Gentianae 0.1% Fructus Tribuli 0.1%.Earlier above-mentioned raw materials is all pulverized except vinegar and vinegar mixed soaking 10 days again, just can be got immersion three liquid and spread upon the tinea unguium last time every day, two weeks is a course of treatment.Treatment tinea unguium 14 examples are smeared total effective rate 100%, through the treatment of two courses of treatment; Remove two examples in the past with Western medicine oral medication mistake, outside existing curative effect is not obvious, other 12 example; 10 examples are all fully recovered through the treatment of two courses of treatment, and 2 examples are all fully recovered through the treatment of four courses of treatment.

Claims (5)

1. external used medicine of treating tinea unguium contains the following composition of weight ratio: vinegar 93%~95%, Radix Tripterygii Wilfordii 3%~4%, Radix Stephaniae Tetrandrae 1.8%~2.5%, Radix Gentianae 0.1%~0.3%, Fructus Tribuli 0.1%~0.2%
2. according to the external used medicine of the treatment tinea unguium of claim 1, it is characterized in that containing the following composition of weight proportion: vinegar 95%, Radix Tripterygii Wilfordii 3%, Radix Stephaniae Tetrandrae 1.8%, Radix Gentianae 0.1%, Fructus Tribuli 0.1%.
3. the external used medicine of treatment tinea unguium according to claim 1 and 2 is characterized in that vinegar is to be made up of acetic acid and the rice vinegar weight ratio by 1: 6.
4. the external used medicine of treatment tinea unguium according to claim 1 and 2 is characterized in that: the Cortex Dictamni that adds 1% weight.
5. the external used medicine of treatment tinea unguium according to claim 3 is characterized in that: the Cortex Dictamni that adds 1% weight.
CN2011103380827A 2011-10-31 2011-10-31 External medicine for treating onychomycosis Pending CN102357121A (en)

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Application Number Priority Date Filing Date Title
CN2011103380827A CN102357121A (en) 2011-10-31 2011-10-31 External medicine for treating onychomycosis

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CN102357121A true CN102357121A (en) 2012-02-22

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902992A (en) * 2016-06-28 2016-08-31 郑州雷曼药业有限公司 Externally applied medicinal gel for treating onychomycosis and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009132342A1 (en) * 2008-04-25 2009-10-29 Nanobio Corporation Nanoemulsions for treating fungal, yeast and mold infections
CN101766751A (en) * 2010-03-04 2010-07-07 河北理工大学 Prescription of modified zinc oxide with vinegar-soaked mashed garlic for onychomycosis treatment

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009132342A1 (en) * 2008-04-25 2009-10-29 Nanobio Corporation Nanoemulsions for treating fungal, yeast and mold infections
CN101766751A (en) * 2010-03-04 2010-07-07 河北理工大学 Prescription of modified zinc oxide with vinegar-soaked mashed garlic for onychomycosis treatment

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
姜烜星等: "龙牡洗剂治疗真菌感染440例疗效观察", 《中国社区医师.医学专业半月刊》 *
李玉琴等: "《常见中药不良反应及治疗》", 31 May 2002 *
王海丽: "《中草药家庭治疗.皮肤病》", 31 December 2000 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902992A (en) * 2016-06-28 2016-08-31 郑州雷曼药业有限公司 Externally applied medicinal gel for treating onychomycosis and preparation method thereof

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