CN102335324A - Chinese medicinal herb decoction for treating acne vulgaris - Google Patents

Abstract

The invention relates to the field of medicament formulation and particularly relates to a Chinese medicinal herb decoction for treating an acne vulgaris. The Chinese medicinal herb decoction is characterized by comprising the following steps of: using honeysuckle, sophora flavescens, Chinese honeylocust spine, cortex moutan, radix rehmanniae, Indian dendranthema flower, bulbus fritillariae thunbergii, earthworm, loquat leaf, prunella asiatica, and rhizoma coptidis as raw material medicaments; mixing the raw material medicaments and soaking the mixture with water; and boiling out the mixture and removing dregs to obtain filtrate. The raw material medicaments comprise the following ingredients in parts by weight: 27-32 parts of the honeysuckle, 12-18 parts of the sophora flavescens, 14-19 parts of the Chinese honeylocust spine, 10-20 parts of the cortex moutan, 12-18 parts of the radix rehmanniae, 27-32 parts of the Indian dendranthema flower, 9-15 parts of the bulbus fritillariae thunbergii, 18-25 parts of the earthworm, 27-32 parts of the loquat leaf, 10-20 parts of the prunella asiatica and 3-7 parts of the rhizoma coptidis. The Chinese medicinal herb decoction provided by the invention has no toxic and side effects, and high treatment efficiency for treating the acne vulgaris.

Description

The Chinese medicine decoction of treatment acne vulgaris

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine decoction of treating acne vulgaris.

Background technology

As everyone knows, acne vulgaris is the chronic inflammation dermatopathy of a kind of hair follicle and sebaceous gland.Mainly betide the face and the chest and back of youth of both sexes, form infringements such as acne, pimple, pustule, tuberosity, cyst, part is lost has cicatrix.He result of investigation shows that in adolescence, the sickness rate of acne is about 90%.Along with the raising of living standards of the people, dietary structure changes to some extent, and the pungent delicious food savoury of happiness food uses various cosmetics, and primary disease has the trend that increases in recent years.Modern medicine thinks that the pathogenic factor of acne and pathogeny are complicated, and main cause is because androgen level rising in the body; Cause the sebaceous gland hyperfunctioning, sebum secretion strengthens, for a large amount of breedings of propionibacterium acnes provide advantageous conditions; Sebaceous gland conduit keratinization in addition; Follicular orifice is blocked, causes the local inflammation reaction, forms struvite pimple, pustule and tuberosity etc.Because this condition of disease influence appearance, reduce quality of life, and the sickness rate height, become one of disease that the modern extremely pays close attention to.In the department of dermatologry field, formed focus for the research of primary disease.The western medicine therapy of treatment acne mainly contains and suppresses local inflammation, anti androgenic therapy, inhibition smegma etc., has certain curative effect, but exists drug resistance and toxic and side effects etc.Acne is the chronic inflammatory disease dermatoses of a kind of hair follicle, sebaceous gland.The traditional Chinese medical science is called " acne ", and it is damp and hot in close relations to think that primary disease forms with the lung stomach, and adolescence's life is vigorous, and is in the green, and sun heat is the body of Shengs partially, and nutrient blood is partial heat day by day, and heat in blood is stopped up outward, fills the body surface channels, QI and blood stasis and sending out; The face nose belongs to lung, and the lung and the large intestine being interior-exteriorly related steams buccal on the lung meridian heat in blood, or the pungent frying rich food dish of surfeit, makes humidogene heat; Tie in gastrointestinal, especially northern area is dry, in addition the pungent stimulation food of happiness food; Can also help heat of wetting, so that damp-heat gluing each other, the damp and hot Yangming Channel that follows is up in buccal, makes sebum secretion cross Sheng; Or multiple sense poison is evil, blocks the hair key, makes stagnation of QI-blood, sends out skin outward and pustulation; With the passing of time stagnation of QI and blood forms the cyst tuberosity." Yizong Jinjian surgery heart method gist " recorded and narrated: " this card forms owing to the lung meridian heat in blood.Every is played broken pimple in the face nose, and shape such as broomcorn millet are considered to be worth doing, and red complexion swells and ache, and breaks out white sauce, with the passing of time all becomes white scales, shape such as Semen Panici miliacei white scales." add: " because eating and drinking without temperance, daily life is careless.Cross the drink pure wine and then light a fire, the cloudy liquid that burns disappears; Cross the water of drinking tea and then give birth to the wet drink that stops; Surfeit five sufferings are then decreased QI and blood; Hinder the hungry full then imapirment of the spleen and stomach of losing; It arises from greasy and surfeit flavour person makes us Rong Wei not from, knot in the fire-toxin more.”

Summary of the invention

The object of the invention is exactly in order to overcome above-mentioned existing technical deficiency, and a kind of Chinese medicine decoction of treating acne vulgaris is provided, and has no toxic and side effects, and treatment acne vulgaris effective percentage is higher.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine decoction of treating acne vulgaris is characterized in that: adopting Flos Lonicerae, Radix Sophorae Flavescentis, Spina Gleditsiae, Cortex Moutan, Radix Rehmanniae, Flos Chrysanthemi Indici, Bulbus Fritillariae Thunbergii, Pheretima, Folium Eriobotryae, Spica Prunellae, Rhizoma Coptidis is crude drug, and crude drug is soaked in water after mixing, and removes slag to such an extent that filtrate after decocting; The weight portion of crude drug is Flos Lonicerae 27-32 part, Radix Sophorae Flavescentis 12-18 part; Spina Gleditsiae 14-19 part, Cortex Moutan 10-20 part, Radix Rehmanniae 12-18 part; Flos Chrysanthemi Indici 27-32 part, Bulbus Fritillariae Thunbergii 9-15 part, Pheretima 18-25 part; Folium Eriobotryae 27-32 part, Spica Prunellae 10-20 part, Rhizoma Coptidis 3-7 part.

The weight portion preferable range of raw material of the present invention is: 30 parts of Flos Loniceraes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Spina Gleditsiaes, 15 parts of Cortex Moutans, 15 parts of Radix Rehmanniae, 30 parts of Flos Chrysanthemi Indicis, 12 parts of Bulbus Fritillariae Thunbergiis, 20 parts of Pheretimas, 30 parts of Folium Eriobotryaes, 15 parts of Spica Prunellaes, 6 parts of Rhizoma Coptidis.

The invention has the beneficial effects as follows to have no toxic and side effects, treatment acne vulgaris effective percentage is higher.

The specific embodiment

Below in conjunction with embodiment the present invention is done further description:

Embodiment 1:

Present embodiment uses following materials of weight proportions medicine to be a dose of medicine: Flos Lonicerae 30 grams, Radix Sophorae Flavescentis 15 grams, Spina Gleditsiae 15 grams, Cortex Moutan 15 grams, Radix Rehmanniae 15 grams, Flos Chrysanthemi Indici 30 grams, Bulbus Fritillariae Thunbergii 12 grams, Pheretima 20 grams, Folium Eriobotryae 30 grams, Spica Prunellae 15 grams, Rhizoma Coptidis 6 grams.With above-mentioned 11 kinds of raw materials mix, soaked 1 hour with clean water, water consumption 1500ml is after intense fire is fried in shallow oil out; Use slow fire boiling instead, extracting juice 200ml, two fry in shallow oil and add water 300ml, decocting extracting juice 200ml; Two fry in shallow oil mixing, fry in shallow oil again to be concentrated into 300ml, and the sterile vacuum packing, decoction gets product.Every day potion divide 2 times oral, each (medicine) being taken before meal 150ml sooner or later.

Therapeutic Principle of the present invention is the heat of lung heat clearing stomach, the merit of have antipruritic, eliminating stagnation concurrently, invigorating blood circulation.Flos Lonicerae has the effect of heat-clearing and toxic substances removing, dispelling wind and heat pathogens in the component of the present invention; Has broad-spectrum antibacterial action; Pathogenic bacterium such as staphylococcus aureus, dysentery bacterium there is stronger inhibitory action; Several diseases pathogenic microorganisms such as leptospira, influenza virus and pathogenic moulds are also had inhibitory action, and modern medicine study confirms that Flos Lonicerae is that propionibacterium acnes medium sensitivity medicine has tangible antiinflammatory and refrigeration function.Radix Sophorae Flavescentis has heat clearing and damp drying, the parasiticidal effect of diuresis.Modern pharmacological research shows; The Chinese medicine Radix Sophorae Flavescentis mainly contains multiple alkaloid such as matrine, sophor-anol, caulophylline, anagyrine and flavonoid such as compositions such as picrol C, Radix Sophorae Flavescentis flavone; Decoct has inhibitory action to tubercule bacillus, dysentery bacterium, escherichia coli, propionibacterium acnes and various skin fungus, and can reduce sebum secretion.Spina Gleditsiae is the Spina jujubae of Gleditsia officinalis, has another name called SPINA GLEDITSIAE.Property and flavor of peppery and warm.Function detumescence and apocenosis, wind dispelling insecticide.Be used for skin sore from the beginning of or the card of difficulty in discharging of pus and tinea, leprosy etc.Cortex Moutan has the function of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, and paeonol wherein and glucoside composition all have antiinflammatory action, and its decoct all has inhibitory action to dysentery bacterium, Bacillus typhi, golden yellow grape coccus, propionibacterium acnes and pathogenic dermatophytes.The Pheretima blood circulation promoting and blood stasis dispelling is gone into liver spleen lung meridian, clearing away heat and alleviating pain, collateral dredging, diuresis, relieving asthma, blood pressure lowering, use the effect of its heat clearing and blood circulation promoting in this utilization.Radix Rehmanniae has the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Use the effect of its clearing away heat and cooling blood here.Flos Chrysanthemi Indici has the effect of heat-clearing and toxic substances removing, and staphylococcus aureus, diphtheria corynebacterium and dysentery bacterium etc. are had inhibitory action.Bulbus Fritillariae Thunbergii has removing heat-phlegm, opens the effect of Disperse hepatic depression." book on Chinese herbal medicine just " sayed its " fall mental disorder most, kind relieving stagnation is separated pyretic toxicity and treated sore throat, scrofula, acute mastitis carbuncle on the back, all carbuncle and ulcer toxic swellings ".Merit in this its removing heat-phlegm eliminating stagnation of utilization.Folium Eriobotryae has the effect of removing heat from the lung and dissipating phlegm cough-relieving, stopping nausea and vomiting by lowering the adverse flow of QI.Decoct has inhibitory action external to staphylococcus aureus, and ursolic acid has antiinflammatory action.Use its clearing away lung-heat effect at this.Spica Prunellae has clearing away liver-fire, Disperse hepatic depression effect.The Spica Prunellae decoct is external to have inhibitory action in various degree to staphylococcus, Bacillus typhi, dysentery bacterium, escherichia coli etc.Use its heat clearing away eliminating stagnation effect here.Rhizoma Coptidis has the effect of heat clearing and damp drying, eliminating fire and detoxication.Rhizoma Coptidis has very wide antibacterial range, and propionibacterium acnes, dysentery bacterium, Bacillus typhi, escherichia coli, staphylococcus, meningococcus etc. are all had than significant inhibitory effect.This sentences its clear middle burnt wet fire stagnation knot.

But each raw material of the present invention also blended embodiment of the listed part by weight of according to the form below is realized.Its processing technique is identical with embodiment 1.(unit: gram)

Below in conjunction with my institute, promptly the clinical preliminary test that carries out of Shandong Province Wendeng Central Hospital, Weihai City is done further, is described in detail the present invention:

1. case is selected: clinically select 90 routine patients at random.

2. diagnostic criteria and the syndrome with " modern dermatological ", " Surgery of Chinese Medicine " and People's Republic of China's industry standard " TCM Dermatology disease diagnosis criterion of therapeutical effect " acne vulgaris is foundation: 1. be more common in person between twenty and fifty, good sending out in the seborrhea position.Skin lesion is hoary hair or blackhead, inflammatory pimple, pus head, but severe patient nodosity, cyst.2. have an eating and drinking without temperance more, the pungent delicious food savoury of surfeit and bringing out.3. the women increases with menoxenia or through preceding skin lesion and increases the weight of.

3. Therapeutic Method: take Chinese medicine decoction 150ml of the present invention at every turn, divide sooner or later and take for twice, 2 weeks were a course of treatment, treated 4 courses of treatment altogether.

4. curative effect is judged: with reference to People's Republic of China's industry standard " TCM Dermatology disease diagnosis criterion of therapeutical effect ".Clinical being almost recovered: skin lesion disappears more than 95%, does not have new rash basically and occurs; Produce effects: skin lesion disappears more than 70%; Take a turn for the better: skin lesion disappears more than 30%; Invalid: skin lesion disappears below 30%.Reject case: 1. the treatment person that takes the other drug in preceding 1 month.2. the person that takes the other drug in the therapeutic process.3. not by pill taker's course of treatment.

5. therapeutic effect: use the present invention to treat 90 examples, produce effects 55 examples as a result, 35 examples that take a turn for the better, invalid 0 example, obvious effective rate is 61.1%, and improvement rate is 38.9%, and inefficiency is 0, and total effective rate is 100%.

Claims (2)

1. Chinese medicine decoction of treating acne vulgaris is characterized in that: adopting Flos Lonicerae, Radix Sophorae Flavescentis, Spina Gleditsiae, Cortex Moutan, Radix Rehmanniae, Flos Chrysanthemi Indici, Bulbus Fritillariae Thunbergii, Pheretima, Folium Eriobotryae, Spica Prunellae, Rhizoma Coptidis is crude drug, and crude drug is soaked in water after mixing, remove slag after decocting filtrating; The weight portion of crude drug is Flos Lonicerae 27-32 part, Radix Sophorae Flavescentis 12-18 part; Spina Gleditsiae 14-19 part, Cortex Moutan 10-20 part, Radix Rehmanniae 12-18 part; Flos Chrysanthemi Indici 27-32 part, Bulbus Fritillariae Thunbergii 9-15 part, Pheretima 18-25 part; Folium Eriobotryae 27-32 part, Spica Prunellae 10-20 part, Rhizoma Coptidis 3-7 part.

2. according to the said a kind of Chinese medicine decoction of treating acne vulgaris of claim 1, it is characterized in that the weight portion of said raw material does, 30 parts of Flos Loniceraes, 15 parts of Radix Sophorae Flavescentiss; 15 parts of Spina Gleditsiaes, 15 parts of Cortex Moutans, 15 parts of Radix Rehmanniae; 30 parts of Flos Chrysanthemi Indicis, 12 parts of Bulbus Fritillariae Thunbergiis, 20 parts of Pheretimas; 30 parts of Folium Eriobotryaes, 15 parts of Spica Prunellaes, 6 parts of Rhizoma Coptidis.