CN102319385B - Medicament for treating emphysema and preparation method thereof - Google Patents

Abstract

The invention discloses a medicament for treating emphysema and a preparation method thereof. The medicament is prepared from poppy capsule, the root of balloonflower, rhizoma anemarrhenae, rheum officinale, liquorice, semen lepidii, liriope and birthwort in a certain ratio. The medicament of the invention has functions of nourishing yin, reducing fire, moistening lung, stopping phlegm, dissolving lump and resolving mass, and can be used for treating emphysema with good effect, fast curative effect and high cure rate.

Description

A kind of emophysematous medicine and preparation method thereof for the treatment of

Technical field

The present invention relates to a kind of emophysematous medicine for the treatment of, belong to the field of Chinese medicines.

Background technology

Emphysema refer to the air flue elasticity attenuation of terminal bronchiole far-end (alveolar bronchiole, alveolar duct, alveolar sac and alveolar), excessive expansion, the pathological state that inflation and lung volume increase or destroy with airway walls simultaneously.By its pathogenic factor emphysema, following several types is arranged: aging-lung emphysema, compensatory emphysema, interstitial emphysema, kitchen range emphysema, other intermittent emphysema, obstructive emphysema.Its clinical manifestation mild symptoms is paid attention to the emphysema degree and is decided, can asymptomatic or only feel to breathe hard when work, motion in early days, be difficult to gradually competent original work, along with emphysema progress, the dyspnea degree increases the weight of thereupon, so that slightly activity is still felt during rest breathing hard even fully, still can feel that in addition the upper abdomen distension is weak, loss of appetite, weight loss, and with symptoms such as cough, expectorations.Typical case's emphysema patient thorax anteroposterior diameter increases, and is barrel chest, and respiratory movement weakens, and vocal fremitus weakens, kowtow the what hyperresonant note, border of cardiac dullness dwindles, and liver dullness circle moves down, and respiratory murmur lowers, sometimes can hear dried, moist rale, increased heart rate, hear sounds is low far away, and P2 is hyperfunction.Western medical treatment is main mainly with antiinflammatory, antitussive symptomatic treatment, but Western medicine medication treatment cycle is long, and expense is high, and side effect is large, easily recurrence.

Summary of the invention

Therefore people to curative effect preferably Chinese medicine have great demand, up to now, also do not find about relevant report of the present invention, the inventor is on the basis of secret prescription handed down in the family from generation to generation, pass through again a large amount of development tests, and by clinical verification, finally the success the Chinese medicine composition of exploring good therapeutic effect, thereby completed the present invention.

Purpose of the present invention just is to provide a kind of emophysematous composition of medicine for the treatment of.

Another object of the present invention just has been to provide the preparation method of this medicine.

The present invention selects Pericarpium Papaveris, Radix Platycodonis, the Rhizoma Anemarrhenae, Radix Peucedani, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, Semen Armeniacae Amarum, Folium Perillae, Flos Farfarae, Semen Lepidii (Semen Descurainiae), the Radix Stemonae, Radix Ophiopogonis, Fructus Aurantii, Radix Asparagi, Fructus Schisandrae Chinensis, the Radix Aucklandiae, Fructus Aristolochiae, Folium Mori, Flos Buddlejae, Semen Trichosanthis and the Rhizoma Pinelliae to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat emophysematous recurrence.Wherein select Pericarpium Papaveris to be because its nature and flavor acid is flat, enter lung, kidney, large intestine channel, astringing lung-QI and relieving cough is arranged, astringing intestine to stop diarrhea, the function of analgesic therapy is controlled chronic cough, chronic diarrhea, chronic dysentery, proctoptosis is had blood in stool, all pains of trusted subordinate's muscles and bones, spermatorrhea, polyuria, leucorrhea.Select Radix Platycodonis to be because its nature and flavor toil is flat, enter lung, stomach warp, lung qi dispersing gas is arranged out, the function of the evacuation of pus of eliminating the phlegm is controlled the exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Select the Rhizoma Anemarrhenae to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, nourishing YIN to lower pathogenic fire is arranged, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Radix Peucedani to be because its nature and flavor are hot, bitter, be slightly cold, return lung meridian, loose wind heat clearing away is arranged, the function of lowering the adverse-rising QI to resolve phlegm is controlled the cough due to pathogenic wind-heat, abundant expectoration, and the expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.Select Radix Et Rhizoma Rhei to be because its nature and flavor are bitter, cold, enter stomach, large intestine, liver footpath, the poison of purging heat is arranged, removing mass is stagnant, the function of clots absorbing blood is controlled the excess-heat constipation, and delirium is gone mad, the food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, the time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia is spitted blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge is urinated red, the carbuncle and ulcer toxic swelling, furuncle, burn.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, return spleen, stomach lung meridian, lung moistening is arranged, the function of detoxifcation is processed with controlling weakness of the spleen and stomach, lack of appetite, stomachache, loose stool, overstrain heating, consumptive lung disease cough.Select Bulbus Fritillariae Cirrhosae to be because its property bitter but sweet flavor is cool, enter lung meridian, the lung moistening eliminating stagnation is arranged, the function that antitussive reduces phlegm is controlled cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis.Select Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, enter lung, large intestine channel, expelling phlegm for arresting cough is arranged, to relieving asthma, the function of intestine moistening is controlled the exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Select Folium Perillae to be because its nature and flavor are hot, temperature enters lung, spleen channel, delivers, and cold expelling is regulated the flow of vital energy, and the function of battalion, the wind and cold that cures cold, and fever with aversion to cold, cough, asthma, distension and fullness of the chest and abdomen, frequent fetal movement, and can solving toxin of fish and crab.Select Flos Farfarae to be because its nature and flavor are hot, temperature enters lung meridian, and nourishing the lung to keep the adverse QI downward is arranged, and the function of the antitussive that reduces phlegm is controlled cough with dyspnea and panted, sore throat.Select Semen Lepidii (Semen Descurainiae) to be because its nature and flavor are hot, hardship is returned lung, urinary bladder channel Great Cold, and eliminating pathogen from the lung for relieving asthma is arranged, and the function of inducing diuresis to remove edema is controlled sputum and stopped up lung, the cough with asthma abundant expectoration, and fullness and distention in the chest and hypochondrium, ascites pleural fluid is swollen, dysuria and pulmonary heart disease edema.Selecting the Radix Stemonae is that tepor enters lung meridian, and gentle lung qi is arranged because of its nature and flavor sweetness and bitterness, cough-relieving, and the function of parasite killing is controlled the cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.Selecting Radix Ophiopogonis is because its property sweet and slightly bitter taste, cold, enters lung, stomach, heart channel, and nourishing YIN and moistening the lung is arranged, the relieving restlessness that clears away heart-fire, and the function of reinforcing stomach reg fluid is controlled dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation, clear thirsty, calentura Tianjin wound, dry mouth and throat, constipation.Selecting Fructus Aurantii is because its nature and flavor toil, cool, enters lung, spleen, large intestine channel, and dispelling the stagnated QI is arranged, row expectorant, the function of removing food stagnancy is controlled chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery, proctoptosis, uterine prolapse.Select Radix Asparagi to be because its nature and flavor sweetness and bitterness is cold, enter lung, kidney channel, YIN nourishing is arranged, moisturize, lung heat clearing, the function of pathogenic fire reducing is controlled fever due to yin deficiency, and cough is spitted blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain is quenched one's thirst, constipation.Select Fructus Schisandrae Chinensis to be because its nature and flavor are sour, temperature enters lung, kidney channel, astringes the lung, and nourishing kidney is promoted the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission is controlled the deficiency of the lung and breathed with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery; Select the Radix Aucklandiae to be because its nature and flavor are arduous, temperature enters lung, liver, spleen channel, and promoting the circulation of QI to relieve pain are arranged, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and vomiting is had loose bowels, dysentery tenesmus, colic of cold type.Select Fructus Aristolochiae to be because its nature and flavor are sweet, cold, enter lung meridian, the lung heat clearing sending down the abnormal ascending QI is arranged, the function of preventing phlegm from forming and stopping coughing is controlled the lung-heat cough with asthma, spitting of blood, aphonia, hemorrhoid complicated by anal fistula swells and ache.Select Folium Mori to be because its property bitter but sweet flavor is cold, enter lung, Liver Channel, expelling wind and clearing away heat is arranged, the function of cooling blood for improving eyesight, the dispelling the wind and dampness pathogens heating, headache, conjunctival congestion, thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Select Flos Buddlejae to be because its nature and flavor are sweet, cool, enter Liver Channel, dispel the wind, removing heat from blood, the profit liver, the function that makes eye bright is controlled conjunctival congestion and swelling pain, many tear photophobia, optic atrohic blindness cataracta, the rotten eye of wind string.Select Semen Trichosanthis to be because its nature and flavor are sweet, cold, return lung, stomach, large intestine channel, moistening the lung and resolving phlegm is arranged, the function of laxation relieving constipation is controlled cough caused by dryness expectorant glutinous, the dryness of the intestine constipation.Select the Rhizoma Pinelliae to be because its nature and flavor are hot, temperature, poisonous, enter spleen, stomach warp, drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass is controlled the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.

The consumption of drug component of the present invention is also that the inventor draws through groping in a large number to sum up, and each amounts of components all has good therapeutic effect in the following weight scope:

Pericarpium Papaveris 25-35 gram Radix Platycodonis 35-45 gram Rhizoma Anemarrhenae 25-35 grams

Radix Peucedani 15-25 gram Radix Et Rhizoma Rhei 15-25 gram Radix Glycyrrhizae 25-35 grams

Bulbus Fritillariae Cirrhosae 25-35 gram Semen Armeniacae Amarum 15-25 gram Folium Perillae 25-35 grams

Flos Farfarae 25-35 gram Semen Lepidii (Semen Descurainiae) 15-25 gram Radix Stemonae 15-25 grams

Radix Ophiopogonis 15-25 gram Fructus Aurantii 15-25 gram Radix Asparagi 15-25 grams

Fructus Schisandrae Chinensis 25-35 gram Radix Aucklandiae 8-15 Rana nigromaculata Semen Oroxyli 15-25 grams

Folium Mori 15-25 gram Flos Buddlejae 15-25 gram Semen Trichosanthis 25-35 grams

The Rhizoma Pinelliae 25-35 gram Mel 60-100 grams

Be preferably

The Pericarpium Papaveris 30 gram Radix Platycodonis 40 gram Rhizoma Anemarrhenae 30 grams

Radix Peucedani 20 gram Radix Et Rhizoma Rhei 20 gram Radix Glycyrrhizae 30 grams

Bulbus Fritillariae Cirrhosae 30 gram Semen Armeniacae Amarum 20 gram Folium Perillae 30 grams

The Flos Farfarae 30 gram Semen Lepidii (Semen Descurainiae) 20 gram Radix Stemonae 20 grams

Radix Ophiopogonis 20 gram Fructus Aurantii 20 gram Radix Asparagi 20 grams

The Fructus Schisandrae Chinensis 30 gram Radix Aucklandiae 10 Rana nigromaculata Semen Oroxyli 20 grams

Folium Mori 20 gram Flos Buddlejae 20 gram Semen Trichosanthis 30 grams

The Rhizoma Pinelliae 30 gram Mel 80 grams

The present invention is secret prescription handed down in the family from generation to generation, medicine is made honeyed pill swallow, and effect is splendid.

Preparation method of the present invention comprises the steps

One, get the raw materials ready

1, Pericarpium Papaveris: choose decontamination, clean, remove handle after running through, shredding is dried;

2, Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

3, the Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, moistens softly, and section is dried;

4, Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;

5, Radix Et Rhizoma Rhei: get the Radix Et Rhizoma Rhei that is cut into small pieces, mix thoroughly with yellow wine, put in food steamer and steam, or put sealing in tank, sit in kettle Steam by water bath saturating, taking-up is dried, and 100 jin of Radix Et Rhizoma Rhei pieces are with 40 jin of yellow wine;

6, Radix Glycyrrhizae: the extracting liquorice sheet, add cooked Mel and boiled water a little, mix thoroughly, slightly vexed, put in pot with slow fire and fry to deepening yellow, tack-free till, taking-up cools, 100 jin, every Radix Glycyrrhizae is with 25-30 jin of cooked Mel;

7, Bulbus Fritillariae Cirrhosae: choose decontamination, water slightly steeps, and pulls out, and moistening is peelled off the heart, dries;

8, Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, and winnows with a dustpan clean;

9, Folium Perillae: choose clean impurity, dry;

10, Flos Farfarae: get the Flos Farfarae that chooses clean and add certain amount of boiling water with refined honey, mix thoroughly, slightly vexed, put in pot and fry to buff with slow fire, tack-free till, taking-up cools, 100 jin of every Flos Farfaraees are with 25 jin of refined honeys;

11, Semen Lepidii (Semen Descurainiae): get crude drug, remove impurity;

12, the Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;

13, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry;

14, Fructus Aurantii: remove flesh, core, edulcoration slightly soaks, and pulls out, moistens softly, can pinch doubling as degree take hands, and section is dried;

15, Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

16, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

17, the Radix Aucklandiae: crude drug in whole is put in clear water cleaned, pull out, moistening made soft in 12-24 hours, and section is dried;

18, Fructus Aristolochiae: get clean Fructus Aristolochiae and add cooked Mel and boiled water a little is mixed thoroughly, slightly vexed, to put in pot with slow fire and fry till tack-free, taking-up cools, and 100 jin of every Fructus Aristolochiaes are with 25-30 jin of cooked Mel;

19, Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;

20, Flos Buddlejae: choose decontamination, well sifted dirt;

21, Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;

22, the Rhizoma Pinelliae: get the clean Rhizoma Pinelliae, soak with cold water and float, avoid Exposure to Sunlight, soak when playing foam after 10 days, 100 jin of every Rhizoma Pinelliaes add 2 jin of Alumens, steep and change water after 1 day again, after extremely mouth is tasted spicy sense is slightly arranged, separately get the Rhizoma Zingiberis Recens section and fry in shallow oil soup, add Alumen and the Rhizoma Pinelliae well-done altogether, take out, dry in the air to sixty percent and do, after moistening, 100 jin of every Rhizoma Pinelliaes are dried in section, with 25 jin, Rhizoma Zingiberis Recens, 12 jin 8 liang-14 jin 8 liang of Alumens.

Two, preparation

1, Pericarpium Papaveris, Radix Platycodonis, the Rhizoma Anemarrhenae, Radix Peucedani, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, Semen Armeniacae Amarum, Folium Perillae, Flos Farfarae, Semen Lepidii (Semen Descurainiae), the Radix Stemonae, Radix Ophiopogonis, Fructus Aurantii, Radix Asparagi, Fructus Schisandrae Chinensis, the Radix Aucklandiae, Fructus Aristolochiae, Folium Mori, Flos Buddlejae, Semen Trichosanthis, the Rhizoma Pinelliae of described weight is broken, grind to form altogether fine powder;

2, get pure Mel, temper with slow fire and make the tender honey of 110 ℃-115 ℃, filter skimming;

3, ground Chinese medicine fine powder and Mel mix and blend are made the large honeyed pill of Semen phaseoli radiati;

4, in process for preparation, adhere to instrument for preventing pill, can smear a small amount of pill oil, the preparation of pill oil: available vegetable oil adds the Mel preparation, and its weight ratio is 4:1 or 5:1.

Medicine of the present invention has nourishing YIN to lower pathogenic fire, and lung moistening stops expectorant, and the function of dissolving lump and resolving mass is used for the treatment of emphysema effective, and curative effect is fast, and cure rate is high.

The specific embodiment

Below further set forth beneficial effect of the present invention by test example, these test examples comprise toxicity test and the clinical observation on the therapeutic effect data of medicine of the present invention.

[test example 1] animal toxicity test

1, select 40 of new zealand rabbits, the male and female dual-purpose, body weight 2-2.5kg is divided into two groups, and wherein one group is the overdose group, and another group is the normal amount group.

2, adopt administration by gavage, the overdose group is 1.5 grams/kg, and normal amount is 0.75 gram/kg, serve on 7 days.

3, result of the test, two groups of rabbit diet are normal, have no adverse reaction, and prove that medicine of the present invention has no side effect.

[test example 2] clinical observation material

1, physical data

Accept out-patient's 200 examples for medical treatment, male's 126 examples wherein, women 74 years old, 20-30 years old age, 40 examples, 31-40 years old 63 example, 41-50 years old 58 example, 39 examples more than 50 years old.

2, diagnostic criteria

Light-duty emphysema: health is weak, dyspnea, and loss of appetite, and with cough, the symptoms such as expectoration;

Heavy emphysema: patient's thorax anteroposterior diameter increases, and respiratory movement weakens, and there is dried moist rale in pulmonary, and the heart rate piece is fast, and P2 is hyperfunction, and cough with asthma is violent.

3, Therapeutic Method

Every day twice, each 15 honeyed pill, 30 days is a course for the treatment of, serve on 2-3 courses for the treatment of.

4, efficacy assessment standard

Produce effects: after 2-3 course of therapy, patient's antisecosis is breathed normally, observes 1 year without the recidivist;

Take a turn for the better: patient's cough alleviates, and muscle power is recovered substantially, breathes unimpeded;

Invalid: as not reach improvement standard person.

5, treatment standard (seeing the following form):

In above-mentioned 2 course of therapy, with light-duty emphysema patient's 110 examples of Drug therapy of the present invention, produce effects 97 examples, 10 examples take a turn for the better, invalid 3 examples, total effective rate 97.27% in 3 course of therapy, is treated heavy emphysema patient's 90 examples, produce effects 83 examples, 1 example that takes a turn for the better, invalid 6 examples, total effective rate is 93.33%.

Claims (3)

1. treat emophysematous medicine for one kind, it is characterized in that: it is to be made by the crude drug in following weight range:

Pericarpium Papaveris 25-35 gram Radix Platycodonis 35-45 gram Rhizoma Anemarrhenae 25-35 grams

Radix Peucedani 15-25 gram Radix Et Rhizoma Rhei 15-25 gram Radix Glycyrrhizae 25-35 grams

Bulbus Fritillariae Cirrhosae 25-35 gram Semen Armeniacae Amarum 15-25 gram Folium Perillae 25-35 grams

Flos Farfarae 25-35 gram Semen Lepidii (Semen Descurainiae) 15-25 gram Radix Stemonae 15-25 grams

Radix Ophiopogonis 15-25 gram Fructus Aurantii 15-25 gram Radix Asparagi 15-25 grams

Fructus Schisandrae Chinensis 25-35 gram Radix Aucklandiae 8-15 Rana nigromaculata Semen Oroxyli 15-25 grams

Folium Mori 15-25 gram Flos Buddlejae 15-25 gram Semen Trichosanthis 25-35 grams

The Rhizoma Pinelliae 25-35 gram Mel 60-100 grams;

Preparation method is the following step:

(1) get the raw materials ready

(1) Pericarpium Papaveris: choose decontamination, clean, remove handle after running through, shredding is dried;

(2) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

(3) Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, moistens softly, and section is dried;

(4) Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;

(5) Radix Et Rhizoma Rhei: get the Radix Et Rhizoma Rhei that is cut into small pieces, mix thoroughly with yellow wine, put in food steamer and steam, or put sealing in tank, sit in kettle Steam by water bath saturating, taking-up is dried, and 100 jin of Radix Et Rhizoma Rhei pieces are with 40 jin of yellow wine;

(6) Radix Glycyrrhizae: the extracting liquorice sheet, add cooked Mel and boiled water a little, mix thoroughly, slightly vexed, put in pot with slow fire and fry to deepening yellow, tack-free till, taking-up cools, 100 jin, every Radix Glycyrrhizae is with 25-30 jin of cooked Mel;

(7) Bulbus Fritillariae Cirrhosae: choose decontamination, water slightly steeps, and pulls out, and moistening is peelled off the heart, dries;

(8) Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, and winnows with a dustpan clean;

(9) Folium Perillae: choose clean impurity, dry;

(10) Flos Farfarae: get the Flos Farfarae that chooses clean and add certain amount of boiling water with refined honey, mix thoroughly, slightly vexed, put in pot and fry to buff with slow fire, tack-free till, taking-up cools, 100 jin of every Flos Farfaraees are with 25 jin of refined honeys;

(11) Semen Lepidii (Semen Descurainiae): get crude drug, remove impurity;

(12) Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;

(13) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry;

(14) Fructus Aurantii: remove flesh, core, edulcoration slightly soaks, and pulls out, moistens softly, can pinch doubling as degree take hands, and section is dried;

(15) Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

(16) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

(17) Radix Aucklandiae: crude drug in whole is put in clear water cleaned, pull out, moistening made soft in 12-24 hours, and section is dried;

(18) Fructus Aristolochiae: get clean Fructus Aristolochiae and add cooked Mel and boiled water a little is mixed thoroughly, slightly vexed, to put in pot with slow fire and fry till tack-free, taking-up cools, and 100 jin of every Fructus Aristolochiaes are with 25-30 jin of cooked Mel;

(19) Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;

(20) Flos Buddlejae: choose decontamination, well sifted dirt;

(21) Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;

(22) Rhizoma Pinelliae: get the clean Rhizoma Pinelliae, soak with cold water and float, avoid Exposure to Sunlight, soak when playing foam after 10 days, 100 jin of every Rhizoma Pinelliaes add 2 jin of Alumens, steep and change water after 1 day again, after extremely mouth is tasted spicy sense is slightly arranged, separately get the Rhizoma Zingiberis Recens section and fry in shallow oil soup, add Alumen and the Rhizoma Pinelliae well-done altogether, take out, dry in the air to sixty percent and do, after moistening, 100 jin of every Rhizoma Pinelliaes are dried in section, with 25 jin, Rhizoma Zingiberis Recens, 12 jin 8 liang-14 jin 8 liang of Alumens;

(2) preparation

(1) Pericarpium Papaveris, Radix Platycodonis, the Rhizoma Anemarrhenae, Radix Peucedani, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, Semen Armeniacae Amarum, Folium Perillae, Flos Farfarae, Semen Lepidii (Semen Descurainiae), the Radix Stemonae, Radix Ophiopogonis, Fructus Aurantii, Radix Asparagi, Fructus Schisandrae Chinensis, the Radix Aucklandiae, Fructus Aristolochiae, Folium Mori, Flos Buddlejae, Semen Trichosanthis, the Rhizoma Pinelliae of described weight is broken, grind to form altogether fine powder;

(2) get pure Mel, temper with slow fire and make the tender honey of 110 ℃-115 ℃, filter skimming;

(3) ground Chinese medicine fine powder and Mel mix and blend are made the large honeyed pill of Semen phaseoli radiati;

(4) in process for preparation, adhere to instrument for preventing pill, can smear a small amount of pill oil, the preparation of pill oil: available vegetable oil adds the Mel preparation, and its weight ratio is 4:1 or 5:1.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

The Pericarpium Papaveris 30 gram Radix Platycodonis 40 gram Rhizoma Anemarrhenae 30 grams

Radix Peucedani 20 gram Radix Et Rhizoma Rhei 20 gram Radix Glycyrrhizae 30 grams

Bulbus Fritillariae Cirrhosae 30 gram Semen Armeniacae Amarum 20 gram Folium Perillae 30 grams

The Flos Farfarae 30 gram Semen Lepidii (Semen Descurainiae) 20 gram Radix Stemonae 20 grams

Radix Ophiopogonis 20 gram Fructus Aurantii 20 gram Radix Asparagi 20 grams

The Fructus Schisandrae Chinensis 30 gram Radix Aucklandiae 10 Rana nigromaculata Semen Oroxyli 20 grams

Folium Mori 20 gram Flos Buddlejae 20 gram Semen Trichosanthis 30 grams

The Rhizoma Pinelliae 30 gram Mel 80 grams.

3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:

(1) get the raw materials ready

(1) Pericarpium Papaveris: choose decontamination, clean, remove handle after running through, shredding is dried;

(2) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

(3) Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, moistens softly, and section is dried;

(4) Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;

(5) Radix Et Rhizoma Rhei: get the Radix Et Rhizoma Rhei that is cut into small pieces, mix thoroughly with yellow wine, put in food steamer and steam, or put sealing in tank, sit in kettle Steam by water bath saturating, taking-up is dried, and 100 jin of Radix Et Rhizoma Rhei pieces are with 40 jin of yellow wine;

(6) Radix Glycyrrhizae: the extracting liquorice sheet, add cooked Mel and boiled water a little, mix thoroughly, slightly vexed, put in pot with slow fire and fry to deepening yellow, tack-free till, taking-up cools, 100 jin, every Radix Glycyrrhizae is with 25-30 jin of cooked Mel;

(7) Bulbus Fritillariae Cirrhosae: choose decontamination, water slightly steeps, and pulls out, and moistening is peelled off the heart, dries;

(8) Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, and winnows with a dustpan clean;

(9) Folium Perillae: choose clean impurity, dry;

(10) Flos Farfarae: get the Flos Farfarae that chooses clean and add certain amount of boiling water with refined honey, mix thoroughly, slightly vexed, put in pot and fry to buff with slow fire, tack-free till, taking-up cools, 100 jin of every Flos Farfaraees are with 25 jin of refined honeys;

(11) Semen Lepidii (Semen Descurainiae): get crude drug, remove impurity;

(12) Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;

(13) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry;

(14) Fructus Aurantii: remove flesh, core, edulcoration slightly soaks, and pulls out, moistens softly, can pinch doubling as degree take hands, and section is dried;

(15) Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

(16) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

(17) Radix Aucklandiae: crude drug in whole is put in clear water cleaned, pull out, moistening made soft in 12-24 hours, and section is dried;

(18) Fructus Aristolochiae: get clean Fructus Aristolochiae and add cooked Mel and boiled water a little is mixed thoroughly, slightly vexed, to put in pot with slow fire and fry till tack-free, taking-up cools, and 100 jin of every Fructus Aristolochiaes are with 25-30 jin of cooked Mel;

(19) Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;

(20) Flos Buddlejae: choose decontamination, well sifted dirt;

(21) Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;

(22) Rhizoma Pinelliae: get the clean Rhizoma Pinelliae, soak with cold water and float, avoid Exposure to Sunlight, soak when playing foam after 10 days, 100 jin of every Rhizoma Pinelliaes add 2 jin of Alumens, steep and change water after 1 day again, after extremely mouth is tasted spicy sense is slightly arranged, separately get the Rhizoma Zingiberis Recens section and fry in shallow oil soup, add Alumen and the Rhizoma Pinelliae well-done altogether, take out, dry in the air to sixty percent and do, after moistening, 100 jin of every Rhizoma Pinelliaes are dried in section, with 25 jin, Rhizoma Zingiberis Recens, 12 jin 8 liang-14 jin 8 liang of Alumens;

(2) preparation

(1) Pericarpium Papaveris, Radix Platycodonis, the Rhizoma Anemarrhenae, Radix Peucedani, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, Semen Armeniacae Amarum, Folium Perillae, Flos Farfarae, Semen Lepidii (Semen Descurainiae), the Radix Stemonae, Radix Ophiopogonis, Fructus Aurantii, Radix Asparagi, Fructus Schisandrae Chinensis, the Radix Aucklandiae, Fructus Aristolochiae, Folium Mori, Flos Buddlejae, Semen Trichosanthis, the Rhizoma Pinelliae of described weight is broken, grind to form altogether fine powder;

(2) get pure Mel, temper with slow fire and make the tender honey of 110 ℃-115 ℃, filter skimming;

(3) ground Chinese medicine fine powder and Mel mix and blend are made the large honeyed pill of Semen phaseoli radiati;

(4) in process for preparation, adhere to instrument for preventing pill, can smear a small amount of pill oil, the preparation of pill oil: available vegetable oil adds the Mel preparation, and its weight ratio is 4:1 or 5:1.