CN102318829A - Compound camellia oil health product with function of blood pressure decreasing, and preparation method thereof - Google Patents
Compound camellia oil health product with function of blood pressure decreasing, and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a compound camellia oil health product with a function of blood pressure decreasing, and a preparation method thereof. The compound camellia oil health product is prepared from the following components: 50-95 parts of camellia oil, 1-10 parts of a eucommia extract, 2-20 parts of a ginkgo extract, 1-10 parts of a sanchi extract, 2-8 parts of soybean lecithin and 0.5-3 parts of an assistant material. The method comprises the following steps: A, preparing the camellia oil; B, mixing the materials; C, carrying out pressing for the resulting viscous mixture to prepare the soft capsule pills. With the present invention, the comprehensive effect of various components in the compound camellia oil health product is adopted, the good function of blood pressure decreasing is provided.
Description
Technical field
The present invention relates to a kind of camellia oil health products and preparation method thereof, relate in particular to a kind of compound camellia oil health products and preparation method thereof with antihypertensive function.Belong to the functional health care food preparing technical field.
Background technology
Hypertension is the topmost hazards that cause angiocardiopathy, often causes the complication of internal organs such as the heart, brain, kidney, and human beings'health in serious harm.2010, Chinese hyperpietic's number surpassed 200,000,000, and also continue to increase in the number with 1,000 ten thousand every year.And hypertension no longer is middle-aged and old " patents ", and the hypertensive illness rate of the people below 30 years old has reached 10%, and the trend of rising is higher than the elderly far away.Angiocardiopathy has become first cause of death of China resident, has statistics to show, in the annual 3000000 dead cardiovascular patients of China, 50% is all relevant with hypertension.Therefore improve understanding, early prevention, treatment are in time had extremely important meaning high blood pressure.
Modern treatment hypertension medication general sequence is: dietotherapy, tea treatment, health care, Chinese medicine are to use Western medicine at last.In order to control blood pressure, except taking medicine, people have found out various methods.In the China that pays attention to dietotherapy, preventing or improve some disease through the food that enters the mouth is common way.Camellia oil refines in wild woody oily section fruit, is one of the world's four big xylophyta oil.In fact the dietotherapy dual-use function of China's camellia oil is superior to olive oil; Except the aliphatic acid composition of two kinds of greases and oil property, nutritional labeling are similar; Tea oil also contains unexistent specific physiological activator Tea Polyphenols of olive oil and camellianin (be the tea saponin, or claim Tea Saponin).The content of monounsaturated fatty acids surpasses olive oil, up to 80%; Tea oil is rich in higher vitamin E, is the twice of olive oil." Chinese pharmacopoeia (nineteen ninety-five version) is recorded tea oil as medicinal oil, tea oil is rich in multiple nutritional components because of it, and for oral administration, external application all has good effectiveness.Often take, can suppress old and feeble, chronic pharyngitis and prevention human body hypertension, artery sclerosis, disease of cardiovascular system are had the excellent prevention effect.
Unsaturated fatty acid content in the camellia oil is the highest in the present edible oil up to 90%.The oleic acid content that human consumption absorbs is high more, and coronary heart disease and hypertension incidence rate and the death rate are low more.The resident in long-term edible camellia oil area, coronary heart disease and hyperpietic are few.
Phytosterol is a kind of natural active matter of effective reduction cholesterol, and it can suppress human body to absorption of cholesterol, plays the reduction cholesterol, the effect of angiocardiopathy preventing.Human body can not synthesizing phytosterol, must from meals, obtain, and edible oil is people absorb phytosterol from meals a important channel.Because camellia oil phytosterol content is low; Reduction DeGrain to cholesterol; One Chinese patent application (CN101869152A) discloses the preparation method of the refining health care camellia oil of a plant sterols and camellia oil compatibility, and the sterol total content reaches 10000-15000mg/L in the camellia oil though this method can make.But the health product that adopts single camellia oil to process does not all have the effect that brings high blood pressure down significantly, thereby need provide a kind of is the compound camellia oil health product with better antihypertensive function of main component with the camellia oil.
Summary of the invention
The present invention is directed to the existing in prior technology defective, provide a kind of compatibility reasonable, the obvious compound camellia oil of blood pressure reduction effect health products.
Another object of the present invention is to provide the preparation method of these compound camellia oil health products.
Compound camellia oil health products of the present invention are processed by following component: (consumption is a weight portion)
Camellia oil 50-95 eucommia ulmoides extracts 1-10 ginkgo biloba extract 2-20
Notogineng Extract 1-10 soybean lecithin 2-8 auxiliary material: 0.5-3.
Prescription preferred weight (part) ratio range of preparation health products of the present invention is:
Camellia oil 60-90 eucommia ulmoides extracts 1-10 ginkgo biloba extract 4-15
Notogineng Extract 1-10 soybean lecithin 3-6 auxiliary material: 1-2.Auxiliary material is made up of sucrose fatty ester and vitamin E, and the weight of each composition (part) proportioning is: sucrose fatty ester 0.5-1, vitamin E 0.5-1.
As preferably, described camellia oil contains the phytosterol total amount and is not less than 10000mg/L, and unsaturated fatty acid content is not less than 80%; Described ginkgo biloba extract is a ginkgo biloba p.e, and general flavone is not less than 15%, and the total lactone of gingko is not less than 3%; Said Notogineng Extract is pseudo-ginseng root or stem-leaf extract, and total saponin is 10-80%.Described health products are said formulations on any pharmacy; As preferably, described health products are soft capsules.
Based on the camellia oil angiocardiopathy preventing; Improve the effect of myocardial function; Cooperate the filling liver kidney of bark of eucommia tool, strengthening the bones and muscles, many effects such as hypotensive, the present invention is intended to develop the antihypertensive product of a kind of camellia oil and eucommia ulmoides extracts compound, and the eucommia ulmoides extracts of employing is that the dry bark of the Eucommiaceae plant bark of eucommia is through the chemical extraction gained; Be aided with ginkgo biloba extract and better effect arranged in treatment coronary heart disease, angina pectoris, uncomfortable in chest, symptom such as breathe hard; Notogineng Extract is significantly regulated blood fat and immunological regulation effect, and the compound synergistic effect is remarkable, has good blood pressure reduction effect.
The method that above-mentioned each component is processed health products soft capsule of the present invention may further comprise the steps:
The preparation of A, camellia oil: the camellia oilseeds through the pulverizing of shelling after the drying, are steamed stir-fry earlier then again after moistening; Make the camellia oil bullion through squeezing again, after obtain edible camellia oil after the depickling, washing, the interpolation phytosterol promptly gets the refining camellia oil by using finished product in this camellia oil again;
B, batch mixing: with the above-mentioned refining camellia oil by using finished product that makes and ginkgo biloba extract, Notogineng Extract, eucommia ulmoides extracts, soybean lecithin compatibility; Add auxiliary material then; At temperature 30-70 ℃, homogeneous batch mixing under the condition of pressure 15MPa-25MPa makes thick shape mixture;
C, above-mentioned thick shape mixture is made the soft capsule pill through pressing.
Wherein adopt fresh camellia oilseeds through after the drying in the steps A, the camellia oilseeds are shelled, powdery is processed into through pulverizer in the back; Raw material earlier through steam or the moistening back of spraying water " the wet steaming fried ", squeeze through expeller and make the tea oil bullion, after refining procedures such as depickling, washing obtain edible camellia oil.Through in this tea oil, adding phytosterol, sterol content is higher than 10000mg/L in detecting tea oil, promptly gets the refining camellia oil by using finished product.
Pressing prepares the soft capsule pill and adopts common method may further comprise the steps among the step C: the first step, prepare capsule material glue.According to the capsule material formula, gelatin is put into the distilled water immersion make its expansion, treat that gelatin dissolves the back and adds unclassified stores in the lump, mix; Second step, the glue sheet.The capsule material glue that taking-up prepares is coated on the smooth plate surface, makes thickness even, then with the heating of about 90 ℃ temperature, makes the surface moisture evaporation, and becoming has certain toughness, certain flexible cushion compound is arranged.The 3rd step, the compacting soft capsule.During small lot batch manufacture, with pelleting mould manual pressing; During production in enormous quantities, normal employing rotation rolling capsule machine is automatically produced.
As preferably, dry back water content is controlled at 5%-6% in the steps A, steams to fry temperature and be controlled at 130-140 ℃, steams to fry the back water content and be controlled at 3%-4%.
As preferably, the temperature of homogeneous batch mixing is 40-60 ℃ among the step B, pressure 20MPa.
40-60 ℃ is advanced compound, and the mixing that utilizes between each component is arranged, and temperature is not very high, also can guarantee the chemically stable of each component.And under 20MPa, be easier to the quick homogeneous of sample.Method through high-pressure homogeneous prepares sample, makes its each component by dispersion, and uneven heterogeneous amalgam becomes homogeneous, single-phase mixture.Sample is through after the high-pressure homogeneous processing, and average grain diameter reduces, thereby makes stability of sample, absorbability, functional raising greatly.
The present invention has the following advantages:
1, to select natural plant for use be raw material in the present invention, and each component is up to specification, utilizes the comprehensive function of various compositions to have antihypertensive function, and is harmless to human non-toxic.
2, the present invention is nutritious, no bitter taste, and taking convenience meets the regulation of state food health legislation.
3, light disease person can use separately.Can unite use with other hypotensor than grave illness disease, can significantly reduce the use amount of common hypotensive Western medicine, result of treatment is obvious, and can slow down or eliminate other complication significantly.
For showing that health products of the present invention have hypotensive result of treatment; Get 50 male SHR rats; Evenly be divided into 4 groups according to pressure value and body weight, i.e. model control group, low dose group of the present invention (compound camellia oil 0.5gkg-1), middle dose groups (compound camellia oil 1.0gkg-1) and high dose group (compound camellia oil 2.0gkg-1), 10 every group; Other gets 10 Wistar rats as the normal control group, 4 weeks of successive administration.Administration 1,2,3,4 is during week, after each is organized rat and weighs, measures systolic pressure (SBP), diastolic pressure (DBP), mean pressure (MBP) and heart rate (HR).
Result of the test shows that tentatively the blood pressure of model control group SHR rat is significantly higher than the blood pressure of normal Wistar rats, and raises along with the increase in age in week; The compound camellia oil can significantly suppress the rising of the blood pressure of SHR rat, and the approach of its effect possibly be to suppress the rising of blood pressure through softening blood vessel.The effect that can suppress the rising of SHR rat of the present invention is described.
1. test objective
Observe the influence of compound camellia oil to spontaneous hypertensive rat (SHR) blood pressure, hypotensive activity provides preliminary experimental basis to spontaneous hypertensive rat for the compound camellia oil.
2. receive the reagent thing
2.1 trial drug
2.1 title: the compound camellia oil, proterties: buff liquid, date received: 20110402, the unit of providing: Inst. of Subtropical Forestry, Chinese Academy of Forestry Sciences, storage procedures: 4 ℃ of preservations.Compound method: face with preceding usefulness 2% sucrose-fatty ester solution and be dissolved to desired concn.
2.2 negative control article
Title: sucrose fatty ester (S-170), Mitsubishi Co., Ltd., lot number is 0Z10940A; 2% sucrose fatty ester solution compound method: get the 20g sucrose fatty ester, add 98 ℃ the distilled water of 1000ml, break up with refiner and stir, after the cooling, be stored in 4 ℃.
3. experimental animal
Cultivars and strains: the SHR rat, rank: the SPF level, sex: male, body weight: 10 ages in week, quantity: 50; The Wistar rat, rank: the SPF level, sex: male, body weight: 10 ages in week, quantity: 10; Source: Shanghai Experimental Animal Center/Shanghai Slac Experimental Animal Co., Ltd. of the Chinese Academy of Sciences [production licence: SCXK (Shanghai) 2007-0005].
4. experiment condition
Barrier system experiment receptacle, temperature: 22 ± 1 ℃, humidity: 50-70%, illumination: 150-200Lx, light and shade replaced in 12 hours, noise＜50dB, occupancy permit: SYXK (Zhejiang) 2008-0115.
Drinking-water: the tap water filter sterilization places autoclaved drinking-water bottle freely to drink.
Feed: full nutrition pellet.
Feeding manner: free diet, give sufficient feed and water in the rat feeding cage, every cage is raised 4 rats, and before the test, every rat is weighed, marker number.
5. reagent and instrument
5.1 reagent and kit
5.1.1 sodium chloride injection, the 250ml/ bottle, content 0.9% is produced by Shapuaisi Pharmaceutical Co., Ltd., Pinghu City, Zhejiang Prov., and lot number is 110108-4;
5.2 instrument and equipment
5.2.1ALC-NIBP rat arteria caudalis non-invasive blood pressure is measured system, Shanghai Alcott bio tech ltd;
5.2.2MLS-3020 autoclave, SANYO GS Electronics Co., Ltd.;
5.2.3AG204-electronic analytical balance Switzerland METTLER company.
6. divide into groups and administration
6.1 dosage setting and group
6.1.1 normal control group: 2% sucrose-fatty ester solution 10mlkg-1;
6.1.2 model control group: 2% sucrose-fatty ester solution 10mlkg-1;
6.1.3 compound camellia oil low dose group: compound camellia oil 0.5gkg-1;
Amount group during 6.1.4 the compound camellia oil is low: compound camellia oil 1.0gkg-1;
6.1.5 compound camellia oil high dose group: compound camellia oil 2.0gkg-1.
6.2 dosage is provided with according to (human dosage the consigner provide)
Compound camellia oil human dosage is used for 3g/ days, calculates by body weight for humans 60kg, and human dosage is 0.05gkg-1; Mouse dosage is calculated as 0.5kg-1,1.0gkg-1 and 2.0gkg-1 with 10,20,40 times of clinical dosage.
6.3 administration concentration
6.3.1 compound camellia oil low dose group: compound camellia oil 0.05gml-1;
6.3.2 dose groups in the compound camellia oil: compound camellia oil 0.10gml-1;
6.3.3 dose groups in the compound camellia oil: compound camellia oil 0.20gml-1.
6.4 method of administration and capacity
Irritate appetite clothes 10mlkg-1 body weight, medicine-feeding way and clinical administration approach basically identical.
7. test method
Get 50 male 10 the week ages the SHR rat raise 20d in advance after; Measure blood pressure basic value and body weight; Evenly be divided into 4 groups according to pressure value and body weight, i.e. dose groups (compound camellia oil 1.0gkg-1) and compound camellia oil high dose group (compound camellia oil 2.0gkg-1) in model control group, compound camellia oil low dose group (compound camellia oil 0.5gkg-1), the compound camellia oil, 10 every group; Other gets 10 Wistar rats as the normal control group; Normal control group and model control group are irritated 2% sucrose-fatty ester solution of stomach 10mlkg-1 body weight, and each administration group rat oral gavage gives corresponding medicine, 4 weeks of successive administration.Administration 1,2,3,4 is during week, after each is organized rat and weighs, measures systolic pressure (SBP), diastolic pressure (DBP), mean pressure (MBP) and heart rate (HR).
8. observation index
8.1 rat body weight, systolic pressure (SBP), diastolic pressure (DBP), mean pressure (MBP) and heart rate (HR).
9. data
Carry out statistical analysis with SPSS13.0 software; Remainder data is with mean ± standard deviation
expression, and measurement data is used t test evaluation result of the test.
10. result of the test
The compound camellia oil is to the influence of spontaneous hypertensive rat body weight
Visible by table 1 result, compare with the normal control group, the preceding body weight of model control group SHR rat administration is apparently higher than rats in normal control group (P＜0.01), and administration 3 week beginning, the model control group rat body weight significantly is lower than rats in normal control group body weight (P＜0.05); With model control group relatively, give 0.5,1.0, the compound camellia oil of 2.0gkg-1 is after 4 weeks, administration group rat body weight have no significant change (P＞0.05).
Table 1: the compound camellia oil is to the influence (g of spontaneous hypertensive rat body weight; N=10,
)
Annotate: compare with the normal control group,
ΔP＜0.05,
The Δ ΔP＜0.01; With the model control group comparative group,
*P＜0.05,
*P＜0.01.
The compound camellia oil is to the influence of spontaneous hypertensive rat systolic pressure (SBP)
Visible by table 2 result, compare with the normal control group, the forward and backward systolic pressure of model control group SHR rat administration is all apparently higher than rats in normal control group systolic pressure (P＜0.01); With model control group relatively, give 0.5,1.0,2.0gkg
-1Compound camellia oil after 4 weeks, high dose group (2.0gkg
-1The compound camellia oil) rat administration 2,3,4 during week systolic pressure significantly reduce (P＜0.05, P＜0.01), middle dose groups (1.0gkg
-1The compound camellia oil) rat administration 2,4 during week systolic pressure significantly reduce (P＜0.05, P＜0.01), low dose group (0.5gkg
-1The compound camellia oil) rat administration 2 during week systolic pressure significantly reduce (P＜0.05).
Table 2: the compound camellia oil is to the influence (mmHg of spontaneous hypertensive rat systolic pressure (SBP); N=10,
)
Annotate: compare with the normal control group,
ΔP＜0.05,
The Δ ΔP＜0.01; With the model control group comparative group,
*P＜0.05,
*P＜0.01.
The compound camellia oil is to the influence of spontaneous hypertensive rat diastolic pressure (DBP)
Visible by table 3 result, compare with the normal control group, the forward and backward diastolic pressure of model control group SHR rat administration is all apparently higher than rats in normal control group systolic pressure (P＜0.01); With model control group relatively, give 0.5,1.0,2.0gkg
-1Compound camellia oil after 4 weeks, high dose group (2.0gkg
-1The compound camellia oil) rat administration 2,3,4 during week diastolic pressure significantly reduce (P＜0.05, P＜0.01), middle dose groups (1.0gkg-
1The compound camellia oil) rat administration 2,4 during week diastolic pressure significantly reduce (P＜0.05, P＜0.01), low dose group (0.5gkg
-1The compound camellia oil) rat administration 2 during week diastolic pressure significantly reduce (P＜0.05).
Table 3: the compound camellia oil is to the influence (mmHg of spontaneous hypertensive rat diastolic pressure (DBP); N=10,
)
Annotate: compare with the normal control group,
ΔP＜0.05,
The Δ ΔP＜0.01; With the model control group comparative group,
*P＜0.05,
*P＜0.01.
The compound camellia oil is to the influence of spontaneous hypertensive rat mean pressure (MBP)
Visible by table 4 result, to compare with the normal control group, the forward and backward mean pressure of model control group SHR rat administration is all apparently higher than rats in normal control group systolic pressure (P＜0.01); With model control group relatively, give 0.5,1.0,2.0gkg
-1Compound camellia oil after 4 weeks, high dose group (2.0gkg
-1The compound camellia oil) rat administration 2,3,4 during week mean pressure significantly reduce (P＜0.05, P＜0.01), middle dose groups (1.0gkg
-1The compound camellia oil) rat administration 2,4 during week mean pressure significantly reduce (P＜0.05, P＜0.01), low dose group (0.5gkg
-1The compound camellia oil) rat administration 2 during week mean pressure significantly reduce (P＜0.05).
Table 4: the compound camellia oil is to the influence (mmHg of spontaneous hypertensive rat mean pressure (MBP); N=10,
)
Annotate: compare with the normal control group,
ΔP＜0.05,
The Δ ΔP＜0.01; With the model control group comparative group,
*P＜0.05,
*P＜0.01.
The compound camellia oil is to the influence of spontaneous hypertensive rat heart rate (HR)
Visible by table 5 result, compare with the normal control group, the forward and backward heart rate of model control group SHR rat administration is all apparently higher than rats in normal control group systolic pressure (P＜0.05, P＜0.01); With model control group relatively, give 0.5,1.0,2.0gkg
-1Compound camellia oil after 4 weeks, each administration group rat heart rate number of times have no significant change (P＞0.05).
Table 5: the compound camellia oil is to the influence (bpm of spontaneous hypertensive rat heart rate (HR); N=10,
)
Annotate: compare with the normal control group,
ΔP＜0.05,
The Δ ΔP＜0.01; With the model control group comparative group,
*P＜0.05,
*P＜0.01.
Above result of the test shows that tentatively the blood pressure of model control group SHR rat is significantly higher than the blood pressure of normal Wistar rats, and raises along with the increase in age in week; The compound camellia oil can significantly suppress the rising of the blood pressure of SHR rat, and the approach of its effect possibly be to suppress the rising of blood pressure through softening blood vessel.Explain that the compound camellia oil can suppress the effect that the SHR rat raises.
Embodiment: take by weighing raw material (Kg) by table 6 proportioning
Embodiment 1:
The preparation of refining mountain camellia oil
Fresh camellia oilseeds through dry back moisture content be controlled at 5%-6% with interior, the camellia oilseeds are shelled, steam through the moistening back of water spray and fry, fry the material temperature and be controlled at 130-140 ℃, steam that water content is 3%-4% after the stir-fry.After make the tea oil bullion through expeller squeezing again.After depickling, washing, clean refining procedure such as flavor grade obtains edible camellia oil.The unsaturated fatty acid content that detects in the tea oil is not less than 80%; Sterol content is not less than 1000mg/L, takes by weighing a certain amount of phytosterol through calculating, with a spot of refining tea oil dissolving; Under agitation add the good phytosterol of dissolving then; Stir, sterol content is higher than 10000mg/L in detecting tea oil, promptly gets the refining camellia oil by using finished product.
The preparation of camellia seed oil soft capsule
According to the weight proportion of embodiment in the table 61 eucommia ulmoides extracts, ginkgo biloba extract, Notogineng Extract, soybean lecithin and sucrose fatty ester are added above-mentioned making in the refining camellia oil by using finished product, add vitamin E then, in 50 ℃ with 20MPa under carry out homogeneous; Make powder ball shape mixture, adjustment soft capsule device carries out pelleting to scope of design, drying at room temperature two days; Reject the defective capsule and pill of outward appearance, the washing capsule and pill is removed surface lubrication oil, obtains the soft capsule semi-finished product; After drying and the cleaning, pick out and detect qualified pill packaging in the plastic-aluminum pressing plate or in the bottle of packing into; Post label, make the hypotensive soft capsule product of camellia oil of the present invention.
The preparation method of embodiment 2-4 repeats no more with embodiment 1.
Specific embodiment described in the present invention only is that the present invention's spirit is illustrated.Person of ordinary skill in the field of the present invention can make various modifications or replenishes or adopt similar mode to substitute described specific embodiment, but can't depart from spirit of the present invention or surmount the defined scope of appended claims.
Although the present invention has been made detailed explanation and has quoted some specific embodiments as proof, to those skilled in the art, only otherwise leave that the spirit and scope of the present invention can be done various variations or correction is obvious.
Claims (9)
1. the compound camellia oil health products with antihypertensive function is characterized in that it is the product of being processed by following materials of weight proportions
Camellia oil 50-95 eucommia ulmoides extracts 1-10 ginkgo biloba extract 2-20
Notogineng Extract 1-10 soybean lecithin 2-8 auxiliary material: 0.5-3.
2. the compound camellia oil health products with antihypertensive function according to claim 1, wherein the weight proportion of each raw material is
Camellia oil 60-90 eucommia ulmoides extracts 1-10 ginkgo biloba extract 4-15
Notogineng Extract 1-10 soybean lecithin 3-6 auxiliary material: 1-2.
3. the compound camellia oil health products with antihypertensive function according to claim 2 is characterized in that auxiliary material is made up of sucrose fatty ester and vitamin E, and the weight proportion of each composition does
Sucrose fatty ester 0.5-1, vitamin E 0.5-1.
4. the compound camellia oil health products with antihypertensive function according to claim 2 is characterized in that described camellia oil contains the phytosterol total amount and is not less than 10000mg/L, and unsaturated fatty acid content is not less than 80%; Described ginkgo biloba extract is a ginkgo biloba p.e, and general flavone is not less than 15%, and the total lactone of gingko is not less than 3%; Said Notogineng Extract is pseudo-ginseng root or stem-leaf extract, and total saponin is 10-80%.
5. according to any described compound camellia oil health products of claim 1-4, it is characterized in that described health products are said formulations on any pharmacy with antihypertensive function.
6. the compound camellia oil health products with antihypertensive function according to claim 5 is characterized in that described health products are soft capsules.
7. described preparation method of claim 6 with compound camellia oil health products of antihypertensive function, this method may further comprise the steps:
The preparation of A, camellia oil: the camellia oilseeds through the pulverizing of shelling after the drying, are steamed stir-fry earlier then again after moistening; Make the camellia oil bullion through squeezing again, after obtain edible camellia oil after the depickling, washing, the interpolation phytosterol promptly gets the refining camellia oil by using finished product in this camellia oil again;
B, batch mixing: with the above-mentioned refining camellia oil by using finished product that makes and ginkgo biloba extract, Notogineng Extract, eucommia ulmoides extracts, soybean lecithin compatibility; Add auxiliary material then; At temperature 30-70 ℃, batch mixing homogeneous under the condition of pressure 15MPa-25MPa makes thick shape mixture;
C, above-mentioned thick shape mixture is made the soft capsule pill through pressing.
8. the preparation method with compound camellia oil health products of antihypertensive function according to claim 7 is characterized in that dry back water content is controlled at 5%-6% in the steps A, steams the stir-fry temperature and is controlled at 130-140 ℃, and steaming is fried the back water content and is controlled at 3%-4%.
9. according to claim 7 or 8 described preparation methods with compound camellia oil health products of antihypertensive function, the temperature that it is characterized in that batch mixing homogeneous among the step B is 40-60 ℃, pressure 20MPa.
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Cited By (7)
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| CN103651958A (en) * | 2013-11-22 | 2014-03-26 | 安徽大平油脂有限公司 | Health oil with efficacities of activating blood and promoting circulation of Qi |
| CN106262890A (en) * | 2016-08-12 | 2017-01-04 | 贵州省玉屏县金心笛油脂开发有限公司 | A kind of tea oil health-care product with hypolipemic function and preparation method thereof |
| CN106190534A (en) * | 2016-08-16 | 2016-12-07 | 贵州石阡佛顶山野生油茶油业有限公司 | A kind of preparation method of blood pressure lowering Oleum Camelliae |
| CN108812938A (en) * | 2018-07-19 | 2018-11-16 | 芷江华兴油业有限公司 | A kind of tea oil and preparation method thereof |
| CN113475713A (en) * | 2021-06-24 | 2021-10-08 | 中国林业科学研究院亚热带林业研究所 | Hickory oil composition with anti-fatigue function and preparation method thereof |
| CN113615836A (en) * | 2021-06-24 | 2021-11-09 | 中国林业科学研究院亚热带林业研究所 | Cathay hickory oil composition with function of reducing blood pressure and preparation method thereof |
| CN113632855A (en) * | 2021-06-24 | 2021-11-12 | 中国林业科学研究院亚热带林业研究所 | Pecan oil composition with blood fat reducing function and preparation method thereof |
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