CN101978891A - Ginkgo flavone-containing oil-based oral emulsion and preparation method thereof - Google Patents
Ginkgo flavone-containing oil-based oral emulsion and preparation method thereof Download PDFInfo
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- CN101978891A CN101978891A CN2010102728566A CN201010272856A CN101978891A CN 101978891 A CN101978891 A CN 101978891A CN 2010102728566 A CN2010102728566 A CN 2010102728566A CN 201010272856 A CN201010272856 A CN 201010272856A CN 101978891 A CN101978891 A CN 101978891A
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- ginkgo biloba
- biloba extract
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Abstract
The invention discloses ginkgo flavone-containing oil-based oral emulsion. The oral emulsion is characterized by consisting of 100 weight parts of grease, 0.001 to 10 weight parts of ginkgo flavone, 0.001 to 0.05 weight part of emulsifier and 0.001 to 0.01 weight part of auxiliary agent. The oil-based oral emulsion, which has antibacterial, antivirus, anti-fatigue and anti-aging effects and effects of adjusting blood fat, reducing blood pressure, reducing blood viscosity, protecting blood vessels of heart and brain, enhancing immunity, delaying dementia, treating eye diseases and improving pancreatic island to treat diabetes, is prepared by emulsifying and dispersing the bamboo leave flavone into the grease.
Description
The present invention relates to a kind of oil base oral liquid that contains additive, particularly a kind of oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT and preparation method thereof.
GINKGO BILOBA EXTRACT is the biological flavone with physiologically active that extracts from ginkgo leaf, and it is a kind of biological anti-oxidant efficiently, is the nutrient of needed by human.It is divided into fat-soluble and water-soluble two big classes, also is a complex set of and has the mixture of mutual synergistic function.The exploitation of GINKGO BILOBA EXTRACT has in recent years caused that the personages of each side such as domestic and international medicine and pharmacology and grocery trade pay close attention to.Have been found that GINKGO BILOBA EXTRACT has the effect that promotes recycling-guard cardiovascular and cerebrovascular, adjusting blood fat, reduces blood viscosity; can strengthen immunologic function, antifatigue; possess antibiotic, antivirus action, possess hypotensive, delay dementia, treat eye disease, improve the effect of pancreas islet treatment diabetes.At present, the food of China, health products and medical industry forward are natural, nutrition, health care, meticulous direction develop, and make the health products of GINKGO BILOBA EXTRACT with health role that vast potential for future development be arranged.
At present, the application of GINKGO BILOBA EXTRACT is more, but most based on tablet, capsule and pill, the aqueous solution, and main performance has publication number to be: the patent of CN1165019, CN1089865, CN1283503, CN1951404 and CN1927200 or application.They are existing obtains water-soluble oral liquid with ginkgo leaf, also have by ginkgolides to obtain the self-emulsifying microemulsion agent, and be active factors but its cardinal principle all is a water-soluble substances with GINKGO BILOBA EXTRACT, all there is a unavailability problem of fat-soluble GINKGO BILOBA EXTRACT.And GINKGO BILOBA EXTRACT is added in the grease and the unique health food that obtains the oil base oral latex emulsion and then make fat-soluble flavonoids obtain absorption of human body yet there are no report at home and abroad, do not see suitability for industrialized production yet.
The objective of the invention is blank and a kind of oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT of providing and preparation method thereof, be scattered in through emulsification by GINKGO BILOBA EXTRACT (can cooperate with auxiliary agent afterwards) and obtain uniform and stable milk in the grease at prior art---have the oil base oral latex emulsion of unique health care.
Content of the present invention is: a kind of oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT is characterized in that being made up of 100 parts of greases (weight), 0.001 part-10 parts of GINKGO BILOBA EXTRACTs and emulsifying agent 0.001-0.05 part.
In the content of the present invention: the described oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT is characterized in that containing auxiliary agent 0.001-0.01 part.
In the content of the present invention: described grease is: at least a in lard, fish oil, rapeseed oil, soybean oil, peanut oil, sesame oil, siritch, oil-sand seed oil, olive oil, camellia seed oil, safflower oil, cottonseed oil, poppy seed oil, wheat-germ oil, maize germ oil, palm oil, sunflower oil and/or the rice bran oil.
In the content of the present invention: described emulsifying agent is: glycerine monoester stearate, dehydration xylitol list hard fatty acids fat, CSL, stearoyl lactic acid are received, at least a in fat glue, hydrogenated rosin glyceride, sucrose stearate fat (S-370), anhydrous sorbitol list palmitic acid lipid (Span40), anhydrous sorbitol monostearate (Span60), anhydrous sorbitol three stearates (Span65) and/or the anhydrous sorbitol list olein (Span80).
In the content of the present invention: described auxiliary agent is citric acid and/or arabo-ascorbic acid.
Also comprise a kind of preparation method who contains the oil base oral latex emulsion of GINKGO BILOBA EXTRACT among the present invention, it is characterized in that comprising the following steps:
A. in the ratio amount of getting of 100 parts of greases (weight), 0.001 part-10 parts of GINKGO BILOBA EXTRACTs and emulsifying agent 0.001-0.05 part;
B. emulsifying agent is added in the grease of liquid condition, stir and make its dissolving evenly;
C. add GINKGO BILOBA EXTRACT, stir, homogeneous and obtain the product that stable emulsification distribution system had both been made.
Also to add auxiliary agent 0.001-0.01 part among the described step C.
In the content of the present invention: described GINKGO BILOBA EXTRACT be meant in the ginkgo biloba p.e can with the general name of the compound of the phenols of smelting iron ion generation concentrated expression, comprise flavonoids, phenolic acid and lactone three major types material.
Grease oral liquid of the present invention, can be according to the different consumer groups' needs, by changing the content of GINKGO BILOBA EXTRACT, utilize the diversification of varieties of grease to develop series of products, and the grease stable performance, have anticancer, anti-sudden change, radioresistance, anti-ageing, remove a series of biologies and physiological and pharmacological activity such as human free radical and reducing pressure and sugar lipopenicillinase.The present invention has no side effect, and along with choosing grease plays reinforcement to its biology and physiological and pharmacological activity effect.
Below by embodiment the present invention is done further specific descriptions.
Embodiment 1. is dissolved in GINKGO BILOBA EXTRACT 1g, citric acid 1g in the 2ml distilled water, add the 2kg that evenly is mixed with 0.5g anhydrous sorbitol list olein (Span80) and do not conform in the camellia seed oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT after high-speed stirred is even.
Embodiment 2. is dissolved in GINKGO BILOBA EXTRACT 20g, citric acid 9g in the 2ml distilled water, add the 20kg that evenly is mixed with 4g anhydrous sorbitol monostearate (Span60) and do not contain in the olive oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT.
Embodiment 3. is dissolved in GINKGO BILOBA EXTRACT 20g, citric acid 9g in the 20ml distilled water, add camellia seed oil and the 10kg that the 10kg evenly be mixed with 4g anhydrous sorbitol list hard fatty acids fat (Span60) do not contain any artificial synthetized oxidation preventive agent and do not contain in the miscella of any artificial synthetized oxidation preventive agent olive oil, high-speed stirring obtains the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT after mixing matter thoroughly.
Embodiment 4. is dissolved in GINKGO BILOBA EXTRACT 1g, citric acid 1g in the 2ml distilled water, add the 2kg that evenly is mixed with 0.5g anhydrous sorbitol list olein (Span80) and do not contain in the soybean oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT after high-speed stirred is even.
Embodiment 5. is dissolved in GINKGO BILOBA EXTRACT 2kg, citric acid 0.9kg in the 2L distilled water, add 2 tons of evenly being mixed with 0.4kg anhydrous sorbitol monostearate (Span60) and do not contain in the refined rapeseed oil of any artificial synthetized oxidation preventive agent, high-speed stirred obtains the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT after evenly.
Embodiment 6. is dissolved in ginkgo brass 10g in the 10ml distilled water, add the 100kg that evenly is mixed with 4g anhydrous sorbitol monostearate (Span60) and do not contain in the refining tea-seed oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT behind the high-speed stirred homogeneous.
Embodiment 7. is with GINKGO BILOBA EXTRACT 100g, citric acid 80g is dissolved in the 200ml distilled water, add the 3kg that evenly is mixed with 25g anhydrous sorbitol list olein (Span80) and 55g modified soy bean lipoid and do not contain in the soybean oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion liquid that stable milky contains GINKGO BILOBA EXTRACT behind the high-speed stirred homogeneous.
Embodiment 8. is with GINKGO BILOBA EXTRACT 50g, citric acid 10g is dissolved in the 100ml distilled water, add the 5kg that evenly is mixed with 25g Foral glyceride and do not contain in the soybean oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT behind the high-speed stirred homogeneous.
Embodiment 9. is dissolved in GINKGO BILOBA EXTRACT 1g, arabo-ascorbic acid 3g in the 10ml distilled water, add the 5kg that evenly is mixed with 2.5g Foral glyceride and do not contain in the soybean oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT behind the high-speed stirred homogeneous.
Embodiment 10. is dissolved in GINKGO BILOBA EXTRACT 5g, citric acid 4g in the 10ml distilled water, adding the 10kg that evenly is mixed with 2g anhydrous sorbitol list olein (Span80) does not contain in the lard of any artificial synthetized oxidation preventive agent, calorify 80 ℃ of following high-speed stirred, cooling obtains the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT behind the homogeneous.
Embodiment 11. is dissolved in GINKGO BILOBA EXTRACT 100g, citric acid 80g in the 200ml distilled water, add the 5kg that evenly is mixed with 25g anhydrous sorbitol list olein (Span80) and 55g modified soy bean lipoid and do not contain in the sunflower oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT after high-speed stirring is mixed thoroughly.
Embodiment 12. is dissolved in GINKGO BILOBA EXTRACT 20g, citric acid 9g in the 20ml distilled water, add sunflower oil and the 10kg that the 10kg evenly be mixed with 4g anhydrous sorbitol list hard fatty acids fat (Span60) do not contain any artificial synthetized oxidation preventive agent and do not contain in the miscella of any artificial synthetized oxidation preventive agent soybean oil, high-speed stirring obtains the oil base oral latex emulsion that stable milky contains GINKGO BILOBA EXTRACT after mixing matter thoroughly.
Embodiment 13. with GINKGO BILOBA EXTRACT 100g, be dissolved in the 100ml distilled water, add the 10kg that evenly is mixed with the 30g stearoyl lactate and do not contain in the soybean oil of any artificial synthetized oxidation preventive agent, obtain the oil base oral latex emulsion liquid that stable milky contains GINKGO BILOBA EXTRACT behind the high-speed stirred homogeneous.
The invention is not restricted to the foregoing description, content of the present invention is described all can implement and have good result.
Claims (7)
1. an oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT is characterized in that being made up of 100 parts of greases (weight), 0.001 part-10 parts of GINKGO BILOBA EXTRACTs and emulsifying agent 0.001-0.05 part.
2. by the described oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT of claim 1, it is characterized in that containing auxiliary agent 0.001-0.01 part.
3. by the described oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT of claim 1, it is characterized in that: described grease is: at least a in lard, fish oil, rapeseed oil, soybean oil, peanut oil, sesame oil, siritch, oil-sand seed oil, olive oil, camellia seed oil, safflower oil, cottonseed oil, poppy seed oil, wheat-germ oil, maize germ oil, palm oil, sunflower oil and/or the rice bran oil.
4. by the described oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT of claim 1, it is characterized in that: described emulsifying agent is: glycerine monoester stearate, dehydration xylitol list hard fatty acids fat, CSL, stearoyl lactic acid are received, at least a in fat glue, hydrogenated rosin glyceride, sucrose stearate fat (S-370), anhydrous sorbitol list palmitic acid lipid (Span40), anhydrous sorbitol monostearate (Span60), anhydrous sorbitol three stearates (Span65) and/or the anhydrous sorbitol list olein (Span80).
5. by the described oil base oral latex emulsion that contains GINKGO BILOBA EXTRACT of claim 2, it is characterized in that: the auxiliary agent of telling is citric acid and/or arabo-ascorbic acid.
6. a preparation method who contains the oil base oral latex emulsion of GINKGO BILOBA EXTRACT is characterized in that comprising the following steps:
A. in the ratio amount of getting of 100 parts of greases (weight), 0.001 part-10 parts of GINKGO BILOBA EXTRACTs and emulsifying agent 0.001-0.05 part;
B. emulsifying agent is added in the grease of liquid condition, stir and make its dissolving evenly;
C. add GINKGO BILOBA EXTRACT, stir, homogeneous and the emulsification distribution system both make product.
7. according to the described preparation method who contains the oil base oral latex emulsion of GINKGO BILOBA EXTRACT of claim 6, it is characterized in that: also will add auxiliary agent 0.001-0.01 part among the described step C.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102728566A CN101978891A (en) | 2010-09-02 | 2010-09-02 | Ginkgo flavone-containing oil-based oral emulsion and preparation method thereof |
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| CN2010102728566A CN101978891A (en) | 2010-09-02 | 2010-09-02 | Ginkgo flavone-containing oil-based oral emulsion and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102318829A (en) * | 2011-08-17 | 2012-01-18 | 中国林业科学研究院亚热带林业研究所 | Compound camellia oil health product with function of blood pressure decreasing, and preparation method thereof |
| CN102934701A (en) * | 2012-12-03 | 2013-02-20 | 徐州绿之野生物食品有限公司 | Gingko nutritional oil and production method thereof |
| CN106261451A (en) * | 2016-08-31 | 2017-01-04 | 金寨县劲春银杏树种植专业合作社 | A kind of preparation method of ginkgo nut fat liquor |
-
2010
- 2010-09-02 CN CN2010102728566A patent/CN101978891A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102318829A (en) * | 2011-08-17 | 2012-01-18 | 中国林业科学研究院亚热带林业研究所 | Compound camellia oil health product with function of blood pressure decreasing, and preparation method thereof |
| CN102934701A (en) * | 2012-12-03 | 2013-02-20 | 徐州绿之野生物食品有限公司 | Gingko nutritional oil and production method thereof |
| CN106261451A (en) * | 2016-08-31 | 2017-01-04 | 金寨县劲春银杏树种植专业合作社 | A kind of preparation method of ginkgo nut fat liquor |
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Addressee: Anji Mingxin Tea Technology Co., Ltd. Document name: Notification of before Expiration of Request of Examination as to Substance |
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Application publication date: 20110223 |