CN102293817A - Traditional Chinese medicine composition for reducing blood sugar and preparation method thereof - Google Patents
Traditional Chinese medicine composition for reducing blood sugar and preparation method thereof Download PDFInfo
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- CN102293817A CN102293817A CN2011102498287A CN201110249828A CN102293817A CN 102293817 A CN102293817 A CN 102293817A CN 2011102498287 A CN2011102498287 A CN 2011102498287A CN 201110249828 A CN201110249828 A CN 201110249828A CN 102293817 A CN102293817 A CN 102293817A
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Abstract
The invention relates to a traditional Chinese medicine composition for reducing blood sugar, and the composition comprises the raw materials of, by mass: 50-70 parts of mushroom, 30-50 parts of Poria cocos, 30-50 parts of root of kudzu vine, 20-30 parts of ginseng, 10-40 parts of folium llicis latifoliae, and 5-15 parts of balsam pear. The preparation method consists of the steps of: extracting the mushroom, Poria cocos and root of kudzu vine with water, concentrating the extracting solution and then microwave drying the extracting solution at a temperature of 50DEG C-70DEG C, thus obtaining an extracted dry material; extracting the folium llicis latifoliae, balsam pear and ginseng with ethanol at a volume ratio of 80-90% in content, subjecting the extracting solution to concentration and then to microwave drying at a temperature of 50DEG C-70DEG C, thus obtaining an extracted dry material; crushing the extracted dry materials respectively and then merging the crushed materials, adding aerosil and mixing them fully and uniformly so as to obtain the traditional Chinese medicine composition for reducing blood sugar. Able to reduce blood sugar, the traditional Chinese medicine composition of the invention has lasting effect, little side effect and obvious effect. The traditional Chinese medicine composition provided in the invention not only can achieve blood sugar reduction within a short period, but also can improve the immune function.
Description
Technical field
The present invention relates to a kind of hypoglycemic Chinese medicine composition and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Diabetes (Diabetes Mellitus) be a complex disease because of syndrome, be since in the body hormone of insulin deficit or antagonism insulin increase, or insulin can not be brought into normal play physiological action and a kind of syndrome of the glucose, protein and the lipid metabolic disorder that cause in target cell.It is characterized by unusual rising of concentration of glucose and glucose in urine in the blood circulation, can occur typical three-many-one-little symptom when blood glucose is too high, i.e. polydipsia, polyuria, polyphagia and lose weight, and with fatigue and weak.Ketoacidosis, hypertonicity diabetic coma can take place in severe patient, and easily merge multiple infection.Along with the prolongation of the course of disease, its metabolism disorder can cause the chronic progressive external pathological changes of histoorgans such as eye, kidney, nerve, blood vessel and heart.If can not get appropriate treatment in time, heart change, cerebrovascular disease, renal failure then can take place, lose the sight of both eyes, lower limb gangrene etc. and the deadly major cause of morbidity that becomes.Because the cause of disease of primary diabetes mellitus is not illustrated so far as yet fully, so diabetes still do not have the radical cure measure so far.Adopt Diet Therapy, exercise therapy, oral antidiabetic drug, insulin and traditional medicine treatment, can only disease controlling, but can't effect a radical cure diabetes at present.
Summary of the invention
Problem to be solved by this invention provides a kind of good effect, hypoglycemic Chinese medicine composition that toxic and side effects is low and preparation method thereof.
Technical scheme provided by the invention is: a kind of hypoglycemic Chinese medicine composition according to the mass fraction, is that raw material makes by 50～70 parts of Lentinus Edodess, 30～50 portions of Poria, 30～50 Radix Puerariaes, 20～30 parts of Radix Ginsengs, 10～40 parts of Folium Ilicis and 5～15 portions of Fructus Momordicae charantiaes.
Described a kind of hypoglycemic Chinese medicine composition according to the mass fraction, is that raw material makes by 60 parts of Lentinus Edodess, 40 parts of Poria, 40 parts of Radix Puerariaes, 25 parts of Radix Ginsengs, 25 parts of Folium Ilicis and 10 portions of Fructus Momordicae charantiaes.
The preparation method of above-mentioned hypoglycemic Chinese medicine composition may further comprise the steps: Lentinus Edodes, Poria and Radix Puerariae water extraction, extracting solution concentrate back microwave drying under 50 ℃～70 ℃ conditions must extract dry thing I; Folium Ilicis, Fructus Momordicae charantiae and Radix Ginseng must extract dry thing II with the ethanol extraction of volume ratio content 80～90%, the concentrated back of extracting solution microwave drying under 50 ℃～70 ℃ conditions; Merge after extracting dry thing I and extracting dry thing II pulverize separately dry powder, the abundant mixing of micropowder silica gel that adds dry powder weight 15% obtains the Chinese medicine composition of blood fat reducing.
The present invention takes this product of afterreaction through hyperglycemic patients and has the function that reduces hyperglycemia, has characteristics such as bioavailability height, taking convenience simultaneously.This product utilization Lentinus Edodes has the effect that improves the animal immune function, gentle with Lentinus Edodes, lastingly, the effect that side effect is little, cooperate other Chinese medicine with blood sugar regulation, as Poria, Radix Puerariae, Fructus Momordicae charantiae, Radix Ginseng, Folium Ilicis etc., the blood sugar lowering compound recipe of composition not only can reach effect of lowering blood sugar in a short time, also can improve the immunologic function of animal, fundamentally support curative effect of the present invention.Not only can be used for the treatment of, also can be used as the health food of auxiliary hyperglycemic.The present invention has the effect of blood sugar lowering, and its effect is lasting, and side effect is little, and effect is obvious.Not only reach hypoglycemic activity in a short time, also can improve immunologic function, fundamentally supported the curative effect of compound recipe.
The present invention relates to a kind of compositions with treatment hyperglycemia.Particularly being principal agent with the Lentinus Edodes, is the compositions with treatment hyperglycemia that accessory drugs develops with the medicine of multiple medicine-food two-purpose.The applicant finds to take Lentinus Edodes, Poria, Radix Puerariae, Fructus Momordicae charantiae, Radix Ginseng, Folium Ilicis can effectively improve hyperglycemia makes each histoorgan generation pathological changes of whole body, causes the generation of acute and chronic complication.As pancreatic function depletion, dehydration, electrolyte disturbance, malnutrition, resistance decline, impaired renal function, neuropathy, retinopathy etc.
The specific embodiment
Embodiment 1:
Hypoglycemic Chinese medicine composition according to the mass fraction, is that raw material makes by 50 parts of Lentinus Edodess, 30 portions of Poria, 30 Radix Puerariaes, 20 parts of Radix Ginsengs, 10 parts of Folium Ilicis and 5 portions of Fructus Momordicae charantiaes.
By said ratio, (conventional decocting in water extracting method: decocted 1.5 hours the first time, filters with water extraction to get Lentinus Edodes, Poria and Radix Puerariae, decocted 1.0 hours for the second time, filter, merge secondary filtrate and get extracting solution), extracting solution concentrates back microwave drying under 50 ℃ of conditions must extract dry thing I; Folium Ilicis, Fructus Momordicae charantiae and Radix Ginseng must extract dry thing II with the ethanol extraction of volume ratio content 80%, the concentrated back of extracting solution microwave drying under 50 ℃ of conditions; Merge after extracting dry thing I and extracting dry thing II pulverize separately dry powder, add the abundant mixing of micropowder silica gel of dry powder weight 15%, granulate, fill bottling, dress box.
Embodiment 2:
Hypoglycemic Chinese medicine composition according to the mass fraction, is that crude drug makes by 60 parts of Lentinus Edodess, 40 parts of Poria, 40 parts of Radix Puerariaes, 25 parts of Radix Ginsengs, 25 parts of Folium Ilicis and 10 portions of Fructus Momordicae charantiaes.
By said ratio, get Lentinus Edodes, Poria and Radix Puerariae water extraction (conventional decocting in water extracting method), extracting solution concentrates back microwave drying under 60 ℃ of conditions must extract dry thing I; Folium Ilicis, Fructus Momordicae charantiae and Radix Ginseng must extract dry thing II with the ethanol extraction of volume ratio content 85%, the concentrated back of extracting solution microwave drying under 60 ℃ of conditions; Merge after extracting dry thing I and extracting dry thing II pulverize separately dry powder, add the abundant mixing of micropowder silica gel of dry powder weight 15%, granulate, fill bottling, dress box.
Embodiment 3:
Hypoglycemic Chinese medicine composition according to the mass fraction, is that crude drug makes by 70 parts of Lentinus Edodess, 40 parts of Poria, 45 parts of Radix Puerariaes, 20 parts of Radix Ginsengs, 35 parts of Folium Ilicis and 10 portions of Fructus Momordicae charantiaes.
By said ratio, get Lentinus Edodes, Poria and Radix Puerariae water extraction (conventional decocting in water extracting method), extracting solution concentrates back microwave drying under 70 ℃ of conditions must extract dry thing I; Folium Ilicis, Fructus Momordicae charantiae and Radix Ginseng must extract dry thing II with the ethanol extraction of volume ratio content 90%, the concentrated back of extracting solution microwave drying under 70 ℃ of conditions; Merge after extracting dry thing I and extracting dry thing II pulverize separately dry powder, add the abundant mixing of micropowder silica gel of dry powder weight 15%, granulate, fill bottling, dress box.
Embodiment 4:
Hypoglycemic Chinese medicine composition according to the mass fraction, is that crude drug makes by 70 parts of Lentinus Edodess, 50 parts of Poria, 50 parts of Radix Puerariaes, 30 parts of Radix Ginsengs, 40 parts of Folium Ilicis and 15 portions of Fructus Momordicae charantiaes.
By said ratio, get Lentinus Edodes, Poria and Radix Puerariae water extraction (conventional decocting in water extracting method), extracting solution concentrates back microwave drying under 65 ℃ of conditions must extract dry thing; Folium Ilicis, Fructus Momordicae charantiae and Radix Ginseng must extract dry thing II with the ethanol extraction of volume ratio content 85%, the concentrated back of extracting solution microwave drying under 65 ℃ of conditions; Merge after extracting dry thing I and extracting dry thing II pulverize separately dry powder, add the abundant mixing of micropowder silica gel of dry powder weight 15%, granulate, fill bottling, dress box.
Adopt high sugar feed to set up the disorderly model of rat blood sugar, this product is compared with the hyperglycemia matched group after giving 30 days by 5,15,30 times of human body recommended amounts are preventative, and three dosage group rat blood sugar levels significantly descend, and two dosage group levels significantly raise.
The hypoglycemic application example:
Name: Chen Lin sex: man's age: 58 existing hyperglycemia medical histories 5 or six years, blood glucose is higher always not down.The Chinese medicine (two) of taking prescription of the present invention after the course of treatment about, (each 2, took continuously 2 months Chinese medicinal capsule agent, every day 2 times.) glucostasis, blood glucose is reduced to 5.4mmol/L by 6.8 preceding mmol/L of treatment before the meal, blood glucose was reduced to 7.2mmol/L by the preceding 8.4mmol/L of treatment in two hours after the meal, it is clear to look thing, eyes are bright, islet cells and recipient cell number obviously increase, and the harmful sour peptide that shows is eliminated, and therapeutic effect is remarkable.
Name: Wang Qi rainbow sex: woman's age: 62 suffered from diabetic history 4 years, took medicine and did not feel any better for many years always, taking the Chinese medicine of prescription of the present invention (three) after the course of treatment, (each 2, took continuously 3 months Chinese medicinal capsule agent, every day 2 times.) before the meal blood glucose by the treatment before 7.4mmol/L reduce to 6.2mmol/L, blood glucose was reduced to 8.6mmol/L by the preceding 11.2mmol/L of treatment in two hours after the meal, and body immunity is improved, and quality of life obviously improves, the patient is energetic, the transference cure of " three-many-one-little ".Diabetic ophthalmopathy, cardiovascular and cerebrovascular disease, complication such as peripheral nerve pathological changes are well solved.The sharp sex of name: Wang Sheng: man's age: 59 suffered from diabetic history more than 6 years,, taking the Chinese medicine of prescription of the present invention (three) after the course of treatment, (each 2, took continuously 3 months Chinese medicinal capsule agent, every day 2 times.) before the meal blood glucose by the treatment before 7.2 mmol/L reduce to 5.4mmol/L, blood glucose was reduced to 7.6mmol/L by the preceding 9.6mmol/L of treatment in two hours after the meal, islet cells obtains nourishing, restore funcitons slowly, and blood glucose steadily descends, progressively normal, extremity are strong, and vision improves, the polydipsia polyuria, symptoms such as dizzy edema obviously alleviate, and hepatic and renal function improves.
Claims (3)
1. a hypoglycemic Chinese medicine composition is characterized in that: according to the mass fraction, be that raw material makes by 50～70 parts of Lentinus Edodess, 30～50 portions of Poria, 30～50 Radix Puerariaes, 20～30 parts of Radix Ginsengs, 10～40 parts of Folium Ilicis and 5～15 portions of Fructus Momordicae charantiaes.
2. a kind of hypoglycemic Chinese medicine composition according to claim 1 is characterized in that: according to the mass fraction, be that raw material makes by 60 parts of Lentinus Edodess, 40 parts of Poria, 40 parts of Radix Puerariaes, 25 parts of Radix Ginsengs, 25 parts of Folium Ilicis and 10 portions of Fructus Momordicae charantiaes.
3. the preparation method of claim 1 or 2 described a kind of hypoglycemic Chinese medicine compositions is characterized in that: may further comprise the steps: Lentinus Edodes, Poria and Radix Puerariae water extraction, extracting solution concentrate back microwave drying under 50 ℃～70 ℃ conditions must extract dry thing I; Folium Ilicis, Fructus Momordicae charantiae and Radix Ginseng must extract dry thing II with the ethanol extraction of volume ratio content 80～90%, the concentrated back of extracting solution microwave drying under 50 ℃～70 ℃ conditions; Merge after extracting dry thing I and extracting dry thing II pulverize separately dry powder, the abundant mixing of micropowder silica gel that adds dry powder weight 15% obtains the Chinese medicine composition of blood fat reducing.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106306171A (en) * | 2016-08-18 | 2017-01-11 | 湖州新驰医药科技有限公司 | Healthcare food for enhancing immunity and lowering blood sugar and preparation method of healthcare food |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698871A (en) * | 2005-05-25 | 2005-11-23 | 北京华昱安然医药科技有限公司 | Health product for assisting blood sugar-decreasing function and its preparation method |
| CN101708302A (en) * | 2009-12-08 | 2010-05-19 | 张为举 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698871A (en) * | 2005-05-25 | 2005-11-23 | 北京华昱安然医药科技有限公司 | Health product for assisting blood sugar-decreasing function and its preparation method |
| CN101708302A (en) * | 2009-12-08 | 2010-05-19 | 张为举 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 任洁: "马齿苋调节血糖作用的研究", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
| 屈立志等: "苦丁茶对大叔肾上腺素性高血糖的影响", 《中药新药与临床药理》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106306171A (en) * | 2016-08-18 | 2017-01-11 | 湖州新驰医药科技有限公司 | Healthcare food for enhancing immunity and lowering blood sugar and preparation method of healthcare food |
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Inventor after: Yuan Xuecai Inventor before: Li Hua Inventor before: Li Jincai |
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Effective date of registration: 20170210 Address after: 233658 Anhui province city Guoyang County, Yi Hao town medicine Street No. 1 Patentee after: Anhui Yuanhetang Pharmaceutical Co., Ltd. Address before: 437100 Xianning Hot Spring Development Zone Industrial Park, Hubei Patentee before: Hubei Kangjin Pharmaceutical Co.,Ltd. |
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Effective date of registration: 20210112 Address after: 236100 No.6, xiaozhouying natural village, zhouying administrative village, Woyang County, Bozhou City, Anhui Province Patentee after: Anhui zhenhetang Pharmaceutical Co.,Ltd. Address before: 233658 No.1, yaocai street, Yimen Town, Woyang County, Haozhou City, Anhui Province Patentee before: ANHUI YUANHETANG PHARMACEUTICAL Co.,Ltd. |
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