CN104337871A - Blood sugar reducing capsule - Google Patents

Blood sugar reducing capsule Download PDF

Info

Publication number
CN104337871A
CN104337871A CN201410546056.7A CN201410546056A CN104337871A CN 104337871 A CN104337871 A CN 104337871A CN 201410546056 A CN201410546056 A CN 201410546056A CN 104337871 A CN104337871 A CN 104337871A
Authority
CN
China
Prior art keywords
capsule
radix
blood sugar
momordicae charantiae
mori
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410546056.7A
Other languages
Chinese (zh)
Inventor
潘苏枫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZHEJIANG CHUNBAO CAPSULES Co Ltd
Original Assignee
ZHEJIANG CHUNBAO CAPSULES Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ZHEJIANG CHUNBAO CAPSULES Co Ltd filed Critical ZHEJIANG CHUNBAO CAPSULES Co Ltd
Priority to CN201410546056.7A priority Critical patent/CN104337871A/en
Publication of CN104337871A publication Critical patent/CN104337871A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a blood sugar reducing capsule, which is prepared from astragalus membranaceus, red ginseng, mulberry, bitter gourd, radix puerariae and folium mori by appropriately extracting active ingredients therein to prepare capsule medicine powder, adding propolis to prepare a capsule shell, and filling the capsule shell with the capsule medicine powder. According to the blood sugar reducing capsule disclosed by the invention, traditional Chinese medicines having an effect of regulating blood sugar are used after being appropriately extracted, so that concentrations of active ingredients in the medicines are higher and are more beneficial for absorption; the blood sugar reducing capsule not only has a function of reducing blood sugar, but also can improve symptoms of dizziness, headache, deficiency and weakness; meanwhile, the capsule can enhance immunity, and can avoid toxic and side effects even after long-term consumption; and the capsule has values of popularization and production.

Description

A kind of Jiangtang capsule
[technical field]
The present invention relates to the technical field of health food and pharmaceutical preparation, particularly a kind of technical field of Jiangtang capsule.
[background technology]
Along with the raising of people's living standard, the patient of diabetes gets more and more, and diabetes have become the commonly encountered diseases, the frequently-occurring disease that threaten human health.The chronic complicating diseases person of diabetes is also quite general, and the death toll that the various complication caused because of cardiovascular disorder, blood circulation obstacle, nervous system disorders cause increases year by year.Medically do not find the way of radical cure diabetes so far yet, patient generally uses insulin or other Western medicine to treat, but the cost of insulin is higher, need intramuscular injection very inconvenient during use, in addition, some patients towards insulin are irritated, then can not use, from current clinical used or be about to application hypoglycemic medicine, various Western medicine has certain limitation and untoward reaction, or even very serious untoward reaction, as caused hypoglycemia, lactic acidosis etc., and chemicals uses every day, larger toxic and side effects is had to Liver and kidney, and Western medicine can only control blood glucose, the symptoms such as the weak breath of diabetes patient is weak can not be improved, life-time service is larger to human injury.
Current needs are a kind of can be prevented and the health product playing therapeutical effect carry out alternative antidiabetic drug, and relevant expert thinks, plays important advantages, and the new Chinese medicine that screening has multiple blood sugar lowering mechanism is one of effective way for the treatment of and containment diabetes de-velopment.Many single medicinal materials or compound preparation all show multiple blood sugar lowering mechanism, as many medicines have the secretion stimulating insulin β cells secrete insulin, glucagon suppression, the sensitivity increasing Insulin receptor INSR, suppress the intestinal absorption of glucose, improve fatty acid metabolism etc. simultaneously, first the medicine can curing diabetes probably obtains from Chinese medicine.Some Chinese medicine preparation before, the direct pulverizing of raw medicinal material un-extracted is used as medicine use, and both there is a large amount of impurity, and be unfavorable for quality control, and utilization ratio of drug is low, onset is slow.
[summary of the invention]
Object of the present invention solves the problems of the prior art exactly, proposes a kind of Jiangtang capsule, can regulate blood glucose, and dizzy, headache can be improved, the deficiency of vital energy is weak, has the effect of enhancing immunity simultaneously.
For achieving the above object, the present invention proposes a kind of Jiangtang capsule, comprise the crude drug of following weight proportion:
Propolis 20 ~ 50 parts, the Radix Astragali 10 ~ 30 parts, Radix Ginseng Rubra 5 ~ 25 parts, Fructus Mori 15 ~ 30 parts, Fructus Momordicae charantiae 5 ~ 30, Radix Puerariae 5 ~ 30,15 ~ 30 parts, Folium Mori.
As preferably, the extracting method of described Radix Puerariae is, the Radix Puerariae of described proportioning is added 65% ~ 75% appropriate ethanol, and heating and refluxing extraction 2 ~ 3 times each 2 ~ 3 hours, then merges reflux extracting liquid.
As preferably, the extracting method of described Radix Ginseng Rubra is, the Radix Ginseng Rubra of described proportioning is added 70% ~ 90% appropriate ethanol, and heating and refluxing extraction 2 ~ 3 times each 2 ~ 3 hours, then merges reflux extracting liquid.
As preferably, the extracting method of described Fructus Momordicae charantiae is, the Fructus Momordicae charantiae of described proportioning is added 70% ~ 90% appropriate ethanol, and heating and refluxing extraction 2 ~ 3 times each 2 ~ 3 hours, then merges reflux extracting liquid, concentrates, is dried to dry powder.
As preferably, the preparation method of described Fructus Mori is that the Fructus Mori of described proportioning are ground into fine powder, crosses 100 mesh sieves.
As preferably, the extracting method of the described Radix Astragali, Folium Mori is, the Radix Astragali of described proportioning and Folium Mori is added the water of weight 10 ~ 12 times, decocts extraction 2 ~ 3 times, and 1.5 ~ 2.5 hours first times, each 1 ~ 2 hour afterwards, merge extractive liquid, was condensed into clear paste.
As preferably, the effective ingredient of described Radix Puerariae extract is Radix Puerariae flavone, and the effective ingredient of Fructus Momordicae charantiae extract is Fructus Momordicae charantiae glucoside and Momordi glucose-reducing polypeptide, and the effective ingredient of Folium Mori extract is deoxynojirimycin.
Beneficial effect of the present invention: the present invention is by using the Chinese medicine having and regulate blood glucose effect, use after suitably extracting, effective ingredient concentration in medicine is higher, be more conducive to absorb, not only there is hypoglycemic effect, and dizzy, headache can be improved, the deficiency of vital energy is weak, has the effect of enhancing immunity simultaneously, long-term taking has no side effect, and has the value promoted and produce.
Feature of the present invention and advantage will be described in detail by embodiment.
[detailed description of the invention]
Diabetics hyperglycemia, mainly due to hypoinsulinism, causes caused by the imbalance of sugar, fat, protein metabolism disorder, nutrient utilization, often shows as clinically: polydipsia, polyphagia, polyuria.
Diabetes are a kind ofly with characteristics of the times " modern civilization diseases ", is also a kind of chronic lifelong disease.Although patient's initial stage subjective symptoms is not too obvious, hyperglycemia causes body disease-resistant power and vis medicatrix naturae to reduce, and is easily subject to sex pheromone infection morbidity.But it is not diabetes are not incurable disease, fearful.Fearful is various diabetic complications, as skin infection, retinopathy, sclerosis of blood vessels, nephropathy etc.As long as diabetics adheres to treatment, strengthen self health consciousness, active adjustment blood glucose, pay attention to diet control, active adjustment immunologic function, enhancing body premunition and vis medicatrix naturae, blood glucose steady in a long-term, just can effectively prevent or delay the generation of complication.
Insulin is by pancreatic tissue cells group: the protein hormone of islet β cell, regulates the metabolism of sugar, fat, protein three major nutrient utilize and store.Long term hyperglycemia continues to stimulate to beta Cell of islet, extracellular fluid osmotic pressure increases, intracellular fluid outwards runs off, and cause its dysfunction even nonfunction, insulin secretion is fewer and feweri, glucose in urine is caused to increase, carbohydrate metabolism disturbance, the fat in body tissue, breaks down proteins energy supply, cause patient's emaciated physique, with fatigue and weak, cause the organ-tissue Progressive symmetric erythrokeratodermia pathological changes such as eye, kidney, blood vessel, heart.
Medicament selection in the present invention:
1, propolis has very strong antioxygenic property and obvious hypoglycemic effect, and has the effect of repair cell prevention of inflammation.
Propolis can eat for a long time, has no side effect.Propolis is one natural little " Drug Storage ", its energy prevention and therapy disease, no side effects simultaneously, there is no Drug resistance, slowly gentle, safe and reliable, long-term taking is only beneficial to human body, does not have harm, and it has an effect regulating comprehensively and repair to each internal organs of human body.Propolis is put down nontoxic, can relievedly eat.
Propolis is fine to the effect controlling diabetes, and propolis regulates blood glucose, comes from propolis and regulates histiocyte to sugar, fat, protein three major nutrient oxidative metabolism function, promote glycolysis, promote that exogenous glucose synthesizes glycogen, reduce sugared content in blood.Research confirms: propolis regulates blood glucose effect certainly.Propolis can improve beta Cell of islet and target cell membrane is active, improves insulin secretion process, promotes that insulin is combined with target membrane receptor, improves carbohydrate metabolism efficiency.According to report: propolis is used for diabetes, and total effective rate 94%, after taking, can regulate blood glucose very soon.
The approach that propolis reduces blood glucose, prevention and therapy diabetes and complication mainly contains: flavonoid a) in propolis and terpenoid substance have the effect promoting exogenous glucose synthesis hepatic glycogen and two-ways regulation blood glucose, significantly can reduce blood glucose; B) propolis broad-spectrum antibacterial action, promote tissue regeneration effect, be also the main cause of the effectively various infection for the treatment of; C) propolis is a kind of very strong Natural antioxidant, can significantly improve SOD activity, takes the injury that propolis not only can reduce radical pair cell, also can prevent and treat multiple complications; D) propolis has and strengthens the effect of drug effect, insulin injection or take general antidiabetic drug effect bad time, can propolis be added, greatly can improve drug effect, obviously reduce blood glucose; E) effect for reducing blood fat of propolis, improves blood circulation, and has antioxidation, protection vascular effects, and this is the major reason controlling diabetes and all complication; The materials such as the flavonoid f) in propolis, glycoside, can strengthen the activity of adenosinetriphosphataes, it is the important sources of body energy, the effect have supplying energy, regaining one's strength; G) Flavonoid substances in propolis, polysaccharide material have adjustment body metabolism, strengthen the effect of immunocompetence.Therefore, be improve human body premunition, improve the overall quality, prevent the important foundation of complication; H) trace element of rich content in propolis, also has important effect in the control of diabetes.
2, the DNJ in Folium Mori can block the absorption of glucose in intestinal, and Folium Mori have wind and heat dispersing, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving in addition, the effect such as nervous system regulation and lipid metabolism.
In China, Folium Mori are also a kind of medicine since ancient times, there is cough-relieving, the effects such as anti-hypertension, important component contained in Folium Mori is alkaloid compound, wherein the most important thing is deoxynojirimycin (1-Deoxynojimycin, be called for short DNJ), modern medicine proves: after DNJ enters human body, saccharase in human body can be suppressed, maltase, alpha-glucosaccharase sugar, α-amylase is to starch, the decomposition of sugar, suppress alpha-glucosidase in body active, suppress the synthesis of sugar, thus block human body to the absorption of sugar, blood glucose is suppressed to rise, reach the effect of preventing and treating diabetes.
Folium Mori are at the rat diabetes that causes alloxan of decortication sterone, or the mice hyperglycemia that epinephrine, glucagon, AIS cause all has hypoglycemic activity.
3, Radix Puerariae have induce sweat bring down a fever, the function of promoting the production of body fluid to quench thirst, antidiarrheal, and the symptom such as stiffness of the nape, dizziness, headache of hypertensive diabetes patient can be improved.
Radix Puerariae extraction flavonoid substances and Folium Mori extract deoxynojirimycin (DNJ) combine and form a kind of novel substance---wash clear sugar element (cics) of pancreas, what Radix Puerariae and Folium Mori contained wash, and " the poison sugar " that deposits in blood can be resolved into micropartical by the clear sugared element of pancreas, makes it penetrate into cell interior and converts energy to; Two-ways regulation blood glucose, recovers self to change sugared instinct simultaneously; The impaired β cell of quick reparation, makes pancreatic cell regeneration, nutrition pancreas, strengthens body immunity.
Mouse stomach gives puerarin, has inhibitory action to model induced by alloxan mice hyperglycemia.To the mice hyperglycemia that epinephrine brings out, only at puerarin used time display hypoglycemic activity.Pueraria lobata has slight hypoglycemic activity to normal rabbits.
4, Radix Ginseng Rubra can not only reduce blood glucose, and takes Radix Ginseng Rubra for a long time and can improve body immunity, resisting fatigue, radioprotective, Tumor suppression, adjustment human endocrine system.
Radix Ginseng Rubra has the hyperglycemia animal caused because of epinephrine and falls hypoglycemic effect; Improve outside symptom to diabetics decapacitation is conscious, also have slight hypoglycemic activity, and have synergism with islets of langerhans.
5, Fructus Momordicae charantiae has dual regulation to blood glucose.
The title of glucokinin enjoyed by Fructus Momordicae charantiae, and the composition playing hypoglycemic activity in Fructus Momordicae charantiae divides by its character that to be mainly two class one classes are alkaloids, as Fructus Momordicae charantiae glucoside, Momordica charantial etc.; Another kind of is protein and peptide, be in Fructus Momordicae charantiae content at most, the most significant component of blood sugar decreasing effect.
The Momordi glucose-reducing polypeptide be isolated to has a variety of.Research finds, Momordi glucose-reducing polypeptide can suppress small intestinal mucosa to the absorption of glucose; By strengthening the activity of muscle endoenzyme, glucose metabolism and utilization in acceleration bodies, make glucose metabolism balance; Promote or improve insulin secretion, or directly playing the effect of similar islets of langerhans rope, affecting the carbohydrate metabolism process in body.
Alkaloids substance contained in Fructus Momordicae charantiae is various, the wherein activity of a kind of enzyme that Fructus Momordicae charantiae glucoside can be relevant to energy metabolism in human activin, promote that cell is to the picked-up of glucose by this enzyme, regulation and control human energy metabolism process, plays the effect for the treatment of diabetes.
6, Radix Astragali Main Function is QI invigorating, improves disease such as the deficiency of vital energy weak grade, enhancing immunity; Fructus Mori mainly have effect such as YIN nourishing, promoting the production of body fluid to quench thirst of enriching blood, and improve the symptom that diabetes patient is thirsty.
The invigorating middle warmer of the Radix Astragali, QI invigorating, the cloudy fixing striae of liter and Radix Rehmanniae YIN nourishing, the effect of supporting essence of reinforcing the kidney can prevent precise and tiny the sewing of diet, make glucose in urine transfer feminine gender to.The Radix Astragali have reduce blood viscosity, reduce thrombosis, reduce blood pressure, cardioprotection, two-ways regulation blood glucose, free radical resisting damage, defying age, anti-hypoxia, antitumor, the effect of enhancing human body immunity power.
Astragalus polysaccharides can promote that human serum and hepatic protein upgrade, and is dual regulation, has no significant effect euglycemia carbohydrate metabolism, significantly can reduce the blood sugar level of human body after glucose load.
It is one of its nourishing yin effect mechanism that Fructus Mori reduces silk erythrocyte membrane Na+-K+-ATP enzymatic activity, the dizziness that treatment diabetes cause, tinnitus, the disease such as thirsty clearly.
Below in conjunction with detailed description of the invention, the present invention is described in further detail.
Formula: propolis 160g Radix Astragali 80g Radix Ginseng Rubra 40g Fructus Mori 40g
Fructus Momordicae charantiae 20g Radix Puerariae 20g Folium Mori 40g
The extracting method of Radix Puerariae is, Radix Puerariae is added 75% appropriate ethanol, heating and refluxing extraction 3 times, each 2 hours, then merges backflow Radix Puerariae extracting solution.
The extracting method of Radix Ginseng Rubra is, Radix Ginseng Rubra is added 80% appropriate ethanol, heating and refluxing extraction 3 times, each 2 hours, then merges backflow red ginseng extract.
The extracting method of Fructus Momordicae charantiae is, Fructus Momordicae charantiae is added 80% appropriate ethanol, heating and refluxing extraction 3 times, each 2 hours, then merges backflow balsam pear extract, concentrates, is dried to dry powder.
The preparation method of Fructus Mori is that Fructus Mori are ground into fine powder, crosses 100 mesh sieves.
The extracting method of the Radix Astragali, Folium Mori is, the Radix Astragali and Folium Mori is added the water of weight 10 times, decocts extraction 3 times, 2 hours first times, each 1.5 hours afterwards, merges Radix Astragali Mori folium extract, is condensed into the clear paste that relative density is 1.18 ~ 1.22.
Adding ethanol in Radix Astragali Mori folium extract makes alcohol content reach 60%, stirs evenly, and leaves standstill 40 hours, obtains alcohol and mix liquid; Merge backflow Radix Puerariae extracting solution, backflow red ginseng extract and alcohol mix liquid and reclaim ethanol, be concentrated into the thick paste (60 DEG C) that relative density is 1.28-1.32, add Fructus Momordicae charantiae powder, mixing, dry, pulverize, and crosses 100 mesh sieves (particle diameter 0.15 ㎜).
Water, glycerol, gelatin are poured in glue pot by 2:1:2, then adds propolis, through fully mixing, then send into production line and make capsule shells.
Medicated powder is before filled in capsule shells, completes the preparation of Jiangtang capsule.
The present invention is by using the Chinese medicine having and regulate blood glucose effect, use after suitably extracting, effective ingredient concentration in medicine is higher, be more conducive to absorb, not only there is hypoglycemic effect, and dizzy, headache can be improved, the deficiency of vital energy is weak, has the effect of enhancing immunity simultaneously, long-term taking has no side effect, and has the value promoted and produce.
Above-described embodiment is to explanation of the present invention, is not limitation of the invention, anyly all belongs to protection scope of the present invention to the scheme after simple transformation of the present invention.

Claims (7)

1. a Jiangtang capsule, is characterized in that: the crude drug comprising following weight proportion:
Propolis 20 ~ 50 parts, the Radix Astragali 10 ~ 30 parts, Radix Ginseng Rubra 5 ~ 25 parts, Fructus Mori 15 ~ 30 parts, Fructus Momordicae charantiae 5 ~ 30, Radix Puerariae 5 ~ 30,15 ~ 30 parts, Folium Mori.
2. a kind of Jiangtang capsule as claimed in claim 1, is characterized in that: the extracting method of described Radix Puerariae is, the Radix Puerariae of described proportioning is added 65% ~ 75% appropriate ethanol, and heating and refluxing extraction 2 ~ 3 times each 2 ~ 3 hours, then merges reflux extracting liquid.
3. a kind of Jiangtang capsule as claimed in claim 1, is characterized in that: the extracting method of described Radix Ginseng Rubra is, the Radix Ginseng Rubra of described proportioning is added 70% ~ 90% appropriate ethanol, and heating and refluxing extraction 2 ~ 3 times each 2 ~ 3 hours, then merges reflux extracting liquid.
4. a kind of Jiangtang capsule as claimed in claim 1, is characterized in that: the extracting method of described Fructus Momordicae charantiae is, the Fructus Momordicae charantiae of described proportioning is added 70% ~ 90% appropriate ethanol, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 3 hours, then merge reflux extracting liquid, concentrate, be dried to dry powder.
5. a kind of Jiangtang capsule as claimed in claim 1, is characterized in that: the preparation method of described Fructus Mori is that the Fructus Mori of described proportioning are ground into fine powder, crosses 100 mesh sieves.
6. a kind of Jiangtang capsule as claimed in claim 1, it is characterized in that: the extracting method of the described Radix Astragali, Folium Mori is, the Radix Astragali of described proportioning and Folium Mori are added the water of weight 10 ~ 12 times, decoct extraction 2 ~ 3 times, 1.5 ~ 2.5 hours first times, each 1 ~ 2 hour afterwards, merge extractive liquid, was condensed into clear paste.
7. a kind of Jiangtang capsule according to any one of claim 1 to 6, it is characterized in that: the effective ingredient of described Radix Puerariae extract is Radix Puerariae flavone, the effective ingredient of Fructus Momordicae charantiae extract is Fructus Momordicae charantiae glucoside and Momordi glucose-reducing polypeptide, and the effective ingredient of Folium Mori extract is deoxynojirimycin, is called for short DNJ.
CN201410546056.7A 2014-10-16 2014-10-16 Blood sugar reducing capsule Pending CN104337871A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410546056.7A CN104337871A (en) 2014-10-16 2014-10-16 Blood sugar reducing capsule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410546056.7A CN104337871A (en) 2014-10-16 2014-10-16 Blood sugar reducing capsule

Publications (1)

Publication Number Publication Date
CN104337871A true CN104337871A (en) 2015-02-11

Family

ID=52494863

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410546056.7A Pending CN104337871A (en) 2014-10-16 2014-10-16 Blood sugar reducing capsule

Country Status (1)

Country Link
CN (1) CN104337871A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105533596A (en) * 2015-12-14 2016-05-04 山东天地健生物工程有限公司 Propolis, radix salviae miltiorrhizae and ginkgo leaf capsules and preparation method thereof
CN106110294A (en) * 2016-06-29 2016-11-16 中科和素(天津)医药科技有限公司 A kind of nutritional preparation repairing damaged islet cells and preparation method thereof
CN107412721A (en) * 2017-09-15 2017-12-01 李玉保 A kind of hypoglycemic bitter gourd polypeptide compound capsule and preparation method thereof
CN108434346A (en) * 2018-03-05 2018-08-24 吴俊� It is a kind of for adjust, the herbal cuisine composition and preparation method thereof of auxiliary hyperglycemic
CN108887548A (en) * 2018-05-22 2018-11-27 杜成 A kind of deer pancreas ginseng solid beverage and preparation method thereof
CN116159088A (en) * 2022-10-21 2023-05-26 上海合全实业有限公司 Propolis astragalus root and kudzuvine root soft capsule and preparation process thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1596711A (en) * 2004-08-23 2005-03-23 王美岭 Propolis royal jelly health-care food and its production method
CN101306171A (en) * 2008-05-10 2008-11-19 王跃进 Traditional Chinese medicine capsule for repairing dysinsulinism function to balance blood sugar
US8846061B1 (en) * 2011-03-08 2014-09-30 Mark S. Bezzek Multivitamin-mineral regimens for longevity and wellness

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1596711A (en) * 2004-08-23 2005-03-23 王美岭 Propolis royal jelly health-care food and its production method
CN101306171A (en) * 2008-05-10 2008-11-19 王跃进 Traditional Chinese medicine capsule for repairing dysinsulinism function to balance blood sugar
US8846061B1 (en) * 2011-03-08 2014-09-30 Mark S. Bezzek Multivitamin-mineral regimens for longevity and wellness

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105533596A (en) * 2015-12-14 2016-05-04 山东天地健生物工程有限公司 Propolis, radix salviae miltiorrhizae and ginkgo leaf capsules and preparation method thereof
CN106110294A (en) * 2016-06-29 2016-11-16 中科和素(天津)医药科技有限公司 A kind of nutritional preparation repairing damaged islet cells and preparation method thereof
CN107412721A (en) * 2017-09-15 2017-12-01 李玉保 A kind of hypoglycemic bitter gourd polypeptide compound capsule and preparation method thereof
CN108434346A (en) * 2018-03-05 2018-08-24 吴俊� It is a kind of for adjust, the herbal cuisine composition and preparation method thereof of auxiliary hyperglycemic
CN108887548A (en) * 2018-05-22 2018-11-27 杜成 A kind of deer pancreas ginseng solid beverage and preparation method thereof
CN116159088A (en) * 2022-10-21 2023-05-26 上海合全实业有限公司 Propolis astragalus root and kudzuvine root soft capsule and preparation process thereof

Similar Documents

Publication Publication Date Title
CN104337871A (en) Blood sugar reducing capsule
CN103285231A (en) Medicine composition for diabetes adjunctive therapy and preparation method thereof
CN103446385A (en) Traditional Chinese medicine preparation for treating diabetic complications
CN101142975A (en) Rhodiola root and honey composition and preparation method thereof
CN1596914A (en) Medicine for treating eye disease caused by visceral disease
CN101543248B (en) A cold tea especially suitable for 'three high and one acid' population and method for preparing same
CN102526479A (en) Health-care medicine formula with functions of enhancing immunity and lowering blood sugar
CN102526478A (en) Formula of health-care medicine with functions of strengthening immunity and reducing blood sugar
CN105148077A (en) Health preserving porridge with blood sugar decreasing effect
CN101518595A (en) Medical composition with functions of lowering lipid, reducing fat and oxidation resistance and preparation method thereof
CN104815166B (en) A kind of Chinese medicine composition for treating diabetes and its preparation and application
CN103933346A (en) Blood-glucose-reducing composition and preparation method thereof
CN1329049C (en) Blood sugar- and blood pressure-lowering medicine
CN106421581A (en) Biological traditional Chinese medicine for oral administration for treating diabetes and preparation method thereof
CN106075159A (en) Health tea for metabolic syndrome and preparation method thereof
CN102462787B (en) Chinese medicine composition for treating hypertension and improving hyperlipidemia and preparation method of Chinese medicine composition
CN103525640B (en) Energy-keeping yang-tonifying wine
CN107737280A (en) Chinese medicine composition for treating diabetes and its preparation method and application
CN113018398A (en) Anti-fatigue health product and preparation method thereof
CN102846882A (en) Chinese medicinal composition for reducing blood sugar
CN101637214A (en) Chewing gum having effects of preventing and treating diabetes
CN104413195A (en) Eichhornia-crassipes blood-sugar-reducing tea and preparation method thereof
CN103989940A (en) Traditional Chinese medicine composition for treating diabetes mellitus
CN102824446B (en) Medicinal composition with anti-fatigue effect as well as preparation method and application thereof
CN102145125B (en) Propolis and aweto capsule for treating diabetes

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20150211