CN102292328A - 具有cb2受体激动活性的n-取代饱和杂环砜化合物 - Google Patents

具有cb2受体激动活性的n-取代饱和杂环砜化合物 Download PDF

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CN102292328A
CN102292328A CN2010800053579A CN201080005357A CN102292328A CN 102292328 A CN102292328 A CN 102292328A CN 2010800053579 A CN2010800053579 A CN 2010800053579A CN 201080005357 A CN201080005357 A CN 201080005357A CN 102292328 A CN102292328 A CN 102292328A
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alkyl
methyl
imidazoles
benzo
neo
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安藤一男
岩田康弘
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Raqualia Pharma Inc
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Raqualia Pharma Inc
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pulmonology (AREA)
  • Neurology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
CN2010800053579A 2009-01-22 2010-01-22 具有cb2受体激动活性的n-取代饱和杂环砜化合物 Pending CN102292328A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20203609P 2009-01-22 2009-01-22
US61/202,036 2009-01-22
US21397709P 2009-08-04 2009-08-04
US61/213,977 2009-08-04
PCT/JP2010/000377 WO2010084767A1 (en) 2009-01-22 2010-01-22 N-substituted saturated heterocyclic sulfone compounds with cb2 receptor agonistic activity

Publications (1)

Publication Number Publication Date
CN102292328A true CN102292328A (zh) 2011-12-21

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CN2010800053579A Pending CN102292328A (zh) 2009-01-22 2010-01-22 具有cb2受体激动活性的n-取代饱和杂环砜化合物

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Country Link
US (1) US8653063B2 (ru)
EP (1) EP2379533A4 (ru)
JP (1) JP5816883B2 (ru)
KR (1) KR20110117146A (ru)
CN (1) CN102292328A (ru)
BR (1) BRPI1007202A2 (ru)
CA (1) CA2747801A1 (ru)
MX (1) MX2011007663A (ru)
RU (1) RU2011134868A (ru)
WO (1) WO2010084767A1 (ru)

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CN102432514A (zh) * 2011-12-26 2012-05-02 兰州博实生化科技有限责任公司 1-叔丁氧羰基-3-氟氮杂环丁烷的合成方法
CN116322672A (zh) * 2020-11-12 2023-06-23 株式会社AskAt 2-[3-({1-[2-(二甲基氨基)乙基]-2-(2,2-二甲基丙基)-1h-1,3-苯并二氮唑-5-基}磺酰基)氮杂环丁烷-1-基]乙-1-醇的稳定盐和晶型

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US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
WO2012090179A2 (en) 2010-12-30 2012-07-05 Lupin Limited Isoquinoline derivatives as cannabinoid receptor modulators
WO2012090177A2 (en) 2010-12-30 2012-07-05 Lupin Limited Cannabinoid receptor modulators
CN102276511A (zh) * 2011-06-20 2011-12-14 兰州博实生化科技有限责任公司 1-叔丁氧羰基-3-碘氮杂环丁烷的合成方法
WO2013005168A2 (en) 2011-07-05 2013-01-10 Lupin Limited Cannabinoid receptor modulators
US8633182B2 (en) 2012-05-30 2014-01-21 Boehringer Ingelheim International Gmbh Indanyloxyphenylcyclopropanecarboxylic acids
JP6499077B2 (ja) 2012-10-25 2019-04-10 ザ ジェネラル ホスピタル コーポレイション アルツハイマー病と関連疾患の治療のための併用療法
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
CN110305095A (zh) * 2013-10-22 2019-10-08 综合医院公司 色甘酸衍生物以及成像和治疗的相关方法
JP2019524865A (ja) 2016-08-31 2019-09-05 ザ ジェネラル ホスピタル コーポレイション 神経変性疾患と関連する神経炎症におけるマクロファージ／ミクログリア
AU2017423862A1 (en) 2017-07-20 2020-02-06 Aztherapies, Inc. Powdered formulations of cromolyn sodium and ibuprofen
JP2021529771A (ja) 2018-07-02 2021-11-04 ザ ジェネラル ホスピタル コーポレイション クロモリンナトリウムおよびα−ラクトースの粉末製剤

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102432514A (zh) * 2011-12-26 2012-05-02 兰州博实生化科技有限责任公司 1-叔丁氧羰基-3-氟氮杂环丁烷的合成方法
CN102432514B (zh) * 2011-12-26 2014-05-07 兰州博实生化科技有限责任公司 1-叔丁氧羰基-3-氟氮杂环丁烷的合成方法
CN116322672A (zh) * 2020-11-12 2023-06-23 株式会社AskAt 2-[3-({1-[2-(二甲基氨基)乙基]-2-(2,2-二甲基丙基)-1h-1,3-苯并二氮唑-5-基}磺酰基)氮杂环丁烷-1-基]乙-1-醇的稳定盐和晶型
CN116322672B (zh) * 2020-11-12 2024-04-09 株式会社AskAt 2-[3-({1-[2-(二甲基氨基)乙基]-2-(2,2-二甲基丙基)-1h-1,3-苯并二氮唑-5-基}磺酰基)氮杂环丁烷-1-基]乙-1-醇的稳定盐和晶型

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US20110281840A1 (en) 2011-11-17
WO2010084767A1 (en) 2010-07-29
US8653063B2 (en) 2014-02-18
EP2379533A1 (en) 2011-10-26
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CA2747801A1 (en) 2010-07-29
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