CN102258566B - Composite Chinese herbal medicinal immunopotentiator for sea urchin - Google Patents

Composite Chinese herbal medicinal immunopotentiator for sea urchin Download PDF

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Publication number
CN102258566B
CN102258566B CN 201010181290 CN201010181290A CN102258566B CN 102258566 B CN102258566 B CN 102258566B CN 201010181290 CN201010181290 CN 201010181290 CN 201010181290 A CN201010181290 A CN 201010181290A CN 102258566 B CN102258566 B CN 102258566B
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China
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chinese herbal
sea urchin
herbal medicinal
composite chinese
immunopotentiator
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CN 201010181290
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CN102258566A (en
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王轶南
刘学伟
常亚青
刘艳萍
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Dalian Fisheries University
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Dalian Fisheries University
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Abstract

The invention discloses a composite Chinese herbal medicinal immunopotentiator for sea urchin, comprising the following ingredients: 35-42 wt% of Raidx Astragali, 20-25 wt% of Chinese angelica, 12-18 wt% of Codonopsis pilosula, 8-12 wt% of licorice, 5-10 wt% of sophora flavescens and 5-10 wt% of bighead atractylodes rhizome. The composite Chinese herbal medicinal immunopotentiator is used for a medicated bath of cultured sea urchin or for splashing into the entire pond after water decoction, with reasonable collocation of ingredients. The composite Chinese herbal medicinal immunopotentiator has the following advantages that: the ingredients are used according to the principle of Chinese herbal medicine, can enhance drug effect, simultaneously have no toxicity to sea urchin, no influence to the normal life of sea urchin, and can obviously enhance the body immunity of sea urchin; the composite Chinese herbal medicinal immunopotentiator is degradable under natural conditions with no toxic side effect and no residue in the body of sea urchin; the adding dosage of the composite Chinese herbal medicinal immunopotentiator is small, and the usage is convenient; and the sources of the ingredients are stable, the cost is low and the production technology is simple.

Description

Hemicentrotus seu Strongylocentrotus is used the compound Chinese herb immunostimulant
Technical field:
The present invention relates to a kind of Hemicentrotus seu Strongylocentrotus and use immunostimulant, especially a kind of to Hemicentrotus seu Strongylocentrotus have no side effect, noresidue in the Hemicentrotus seu Strongylocentrotus body, can strengthen the Hemicentrotus seu Strongylocentrotus immunity of organisms, the Hemicentrotus seu Strongylocentrotus that improves the Hemicentrotus seu Strongylocentrotus survival rate uses the compound Chinese herb immunostimulant.
Background technology:
Hemicentrotus seu Strongylocentrotus is one of economic breed variety of northern China coastal area.Along with constantly riseing of Hemicentrotus seu Strongylocentrotus demand and price, Hemicentrotus seu Strongylocentrotus fishery development enjoys stimulation, and Hemicentrotus seu Strongylocentrotus is cultured and got into the large-scale production stage and obtained good benefit.But, in the breeding production of Hemicentrotus seu Strongylocentrotus, but engendered the disease and the phenomena of mortality such as " red spot disease ", " black mouth is sick ", culture to Hemicentrotus seu Strongylocentrotus and caused bigger loss.The disease control to Hemicentrotus seu Strongylocentrotus still rests on ill just doctor's stage; Run counter to the aquatic animal disease prevention and control principle of " treatment is auxilliary; put prevention first ", and adopt antibacterials such as antibiotic more, a large amount of uses of antibiotic medicine all can cause adverse effect to environment and food safety.Chinese herbal medicine has been obtained effect preferably as a kind of green non-pollution medicament in the practice that improves organism immunity of aquatic livestock such as prawn, Fish, Carnis Haliotidis, but up to now, does not still have the special shaping Chinese herbal and crude drugs preparations that improves Hemicentrotus seu Strongylocentrotus immunity.
Summary of the invention:
The present invention does not have to improve specially the technical problem of the shaping Chinese herbal and crude drugs preparations of Hemicentrotus seu Strongylocentrotus immunity in order to solve existing in prior technology, provide a kind of to Hemicentrotus seu Strongylocentrotus have no side effect, noresidue in the Hemicentrotus seu Strongylocentrotus body, can strengthen the Hemicentrotus seu Strongylocentrotus immunity of organisms, the Hemicentrotus seu Strongylocentrotus that improves the Hemicentrotus seu Strongylocentrotus survival rate uses the compound Chinese herb immunostimulant.
Technical solution of the present invention is: a kind of Hemicentrotus seu Strongylocentrotus is used the compound Chinese herb immunostimulant, it is characterized in that each component and percentage by weight are:
The Radix Astragali 35~42%
Radix Angelicae Sinensis 20~25%
Radix Codonopsis 12~18%
Radix Glycyrrhizae 8~12%
Radix Sophorae Flavescentis 5~10%
The Rhizoma Atractylodis Macrocephalae 5~10%.
The optimum weight percentage ratio of each component is:
The Radix Astragali 39%
Radix Angelicae Sinensis 22%
Radix Codonopsis 14%
Radix Glycyrrhizae 10%
Radix Sophorae Flavescentis 7%
The Rhizoma Atractylodis Macrocephalae 8%.
The present invention is a kind of Chinese herbal and crude drugs preparations that strengthens the Hemicentrotus seu Strongylocentrotus immunity of organisms, improves its survival rate that is specifically designed to, and contains six kinds of important component such as the Radix Astragali, Radix Angelicae Sinensis, Radix Codonopsis, Radix Glycyrrhizae, Radix Sophorae Flavescentis and the Rhizoma Atractylodis Macrocephalae, is used to culture the dipping or the full pool spilling head of Hemicentrotus seu Strongylocentrotus after decocting boils.The component collocation rationally has following advantage: (1) raw material when strengthening drug effect, does not have toxicity to Hemicentrotus seu Strongylocentrotus according to the formulation principle of Chinese herbal medicine, does not influence the orthobiosis of Hemicentrotus seu Strongylocentrotus, obviously strengthens the immunity of organisms of Hemicentrotus seu Strongylocentrotus; (2) degradable under field conditions (factors) has no side effect noresidue in the Hemicentrotus seu Strongylocentrotus body; (3) addition is little, and is easy to use; (4) raw materials enjoy stable sources, cheap, production technology is simple.
Embodiment 1:
Get Radix Astragali 38g, Radix Angelicae Sinensis 22g, Radix Codonopsis 14g, Radix Glycyrrhizae 10g, Radix Sophorae Flavescentis 7g and Rhizoma Atractylodis Macrocephalae 9g, according to the medicinal liquid of conventional decocting cooking method system.
With the dose dipping 10 piece health one age Hemicentrotus seu Strongylocentrotus (diameter 2-3cm) of above-mentioned medicinal liquid with 10mg/L, be contrast with dipping Hemicentrotus seu Strongylocentrotus not, randomly draw the coelomic fluid of 5 pieces of Hemicentrotus seu Strongylocentrotuss after 3 days, measure the related immune index.The result shows that coelomocyte density, activity of catalase, superoxide dismutase and the antioxidative activities of dipping Hemicentrotus seu Strongylocentrotus is all apparently higher than matched group (table 1).
Embodiment 2:
Get Radix Astragali 40g, Radix Angelicae Sinensis 20g, Radix Codonopsis 16g, Radix Glycyrrhizae 10g, Radix Sophorae Flavescentis 6g and Rhizoma Atractylodis Macrocephalae 8g, according to the medicinal liquid of conventional decocting cooking method system.
With the dose dipping 10 piece health two age Hemicentrotus seu Strongylocentrotus (diameter 3-5cm) of above-mentioned medicinal liquid with 10mg/L, be contrast with dipping Hemicentrotus seu Strongylocentrotus not, randomly draw the coelomic fluid of 5 pieces of Hemicentrotus seu Strongylocentrotuss after 3 days, measure the related immune index.The result shows that coelomocyte density, activity of catalase, superoxide dismutase and the antioxidative activities of dipping Hemicentrotus seu Strongylocentrotus is all apparently higher than contrast (table 1).
Embodiment 3
Get Radix Astragali 39g, Radix Angelicae Sinensis 22g, Radix Codonopsis 14g, Radix Glycyrrhizae 10g, Radix Sophorae Flavescentis 7g and Rhizoma Atractylodis Macrocephalae 8g, according to the medicinal liquid of conventional decocting cooking method system.
Above-mentioned medicinal liquid is contained the breed pond of 60 pieces of health Hemicentrotus seu Strongylocentrotuss in one age (diameter 2-3cm) with the dose full pool spilling head of 10mg/L, changed water (change water volume be breeding water body 1/3) in per 3 days and replenish fresh liquor to 10mg/L, the dispenser phase kept 15 days.
Breed pond with the adjacent medicinal liquid of not splashing is contrast, measures the related immune index after 45 days.The result shows that coelomocyte density, activity of catalase, superoxide dismutase and the antioxidative activities of dispenser Hemicentrotus seu Strongylocentrotus is all apparently higher than contrast (table 1).
Table 1
Figure GSA00000113314900031

Claims (2)

1. a Hemicentrotus seu Strongylocentrotus is used the compound Chinese herb immunostimulant, it is characterized in that it is the medicinal liquid of medical material after decocting boils by following percentage by weight:
Figure FSB00000887962700011
2. Hemicentrotus seu Strongylocentrotus according to claim 1 is used the compound Chinese herb immunostimulant, it is characterized in that each medical material and percentage by weight are:
Figure FSB00000887962700012
CN 201010181290 2010-05-25 2010-05-25 Composite Chinese herbal medicinal immunopotentiator for sea urchin Expired - Fee Related CN102258566B (en)

Priority Applications (1)

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CN 201010181290 CN102258566B (en) 2010-05-25 2010-05-25 Composite Chinese herbal medicinal immunopotentiator for sea urchin

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107007750A (en) * 2017-06-12 2017-08-04 杜运升 A kind of Chinese medicine preparation of tonifying middle-Jiao and Qi for animals

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
具有免疫功能的中草药;叶水泉;《家庭中医药》;20000831(第08期);48 *
叶水泉.具有免疫功能的中草药.《家庭中医药》.2000,(第08期),48.
张勃等.黑嘴病及生殖对虾夷马粪海胆五种生理生化指标的影响.《中国农业科技导报》.2009,第11卷(第04期),77-82.
黑嘴病及生殖对虾夷马粪海胆五种生理生化指标的影响;张勃等;《中国农业科技导报》;20090831;第11卷(第04期);77-82 *

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