CN102240384A

CN102240384A - Medicament for treating phlegm-stasis accumulating type epilepsy and preparation method thereof

Info

Publication number: CN102240384A
Application number: CN2011102424809A
Authority: CN
Inventors: 陈锐
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-08-23
Filing date: 2011-08-23
Publication date: 2011-11-16
Anticipated expiration: 2031-08-23
Also published as: CN102240384B; CN101919995A

Abstract

The invention discloses a medicament for treating phlegm-stasis accumulating type epilepsy and a preparation method thereof. The medicament is prepared from the following raw materials by weight ratio: 1-3 grams of gentian, 4-6 grams of fiveleaf akebia, 6-9 grams of radix bupleuri, 6-9 grams of radix scutellariae, 6-9 grams of fructus gardeniae, 6-9 grams of angelica sinensis, 12-13 grams of rhizoma alismatis, 6-9 grams of whipformed typhonium rhizome, 6-9 grams of immature bitter orange, 6-9 grams of rhizoma calami, 6-9 grams of lumbricus, 4-6 grams of polygala tenuifolia, 12-13 grams of radix astragali, 12-13 grams of radix codonopsis pilosulae, 12-13 grams of radix curcumae, 12-13 grams of radix salviae miltiorrhizae, 6-9 grams of peach kernels, 4-6 grams of safflower and 6-9 grams of rhizoma ligustici wallichii. A decoction method of the medicament comprises the following steps of: taking the gentians, the fiveleaf akebia, the radix bupleuri, the radix scutellariae, the fructus gardeniae, the angelica sinensis, the rhizoma alismatis, the whipformed typhonium rhizome, the immature bitter orange, the rhizoma calami, the lumbricus, the polygala tenuifolia, the radix astragali, the radix codonopsis pilosulae, the radix curcumae, the radix salviae miltiorrhizae, the peach kernels, the safflower and the rhizoma ligustici wallichii by the weight ratio; placing into a terrine for decocting medicinal herbs, and adding water till a water surface is 2 centimeters higher than a raw material plane; decocting for 15-30 minutes by using slow fire till the water is changed into deep yellow medicine soup; adding water again to ensure that the water surface is 2-3 centimeters higher than the raw material plane; decocting for 10-13 minutes by using the slow fire; and filtering out the medicine soup.

Description

A kind of medicine for the treatment of intermingled phlegm and blood stasis type epilepsy and preparation method thereof

Technical field

The present invention relates to medicine, is a kind of medicine for the treatment of intermingled phlegm and blood stasis type epilepsy and preparation method thereof.

Background technology

Intermingled phlegm and blood stasis type epilepsy is a kind of common epileptics, it generally with tangible brain trauma history or relevant with menstrual cycle is arranged, or see after the apoplexy.This disease symptoms is outbreak repeatedly easily, and concrete symptom has, and faints, and wheezing sound in the throat has headache, dizziness concurrently, and complexion is dark, numb limbs and tense tendons.This disease generally is more common in middle-older patient.This sick medicine of treatment is more at present, and the Chinese medicine Western medicine has.The deficiency of Western medicine manifests gradually, is understood by extensive patients, and therefore, increasing patient selects the treatment by Chinese herbs used.But though existing Chinese medicine all has the produce effects effect, and cure rate is all lower, and relapse rate is higher.

Summary of the invention

The objective of the invention is, a kind of medicine for the treatment of intermingled phlegm and blood stasis type epilepsy and preparation method thereof is provided, mainly treat intermingled phlegm and blood stasis type epilepsy, can eliminate various symptoms as early as possible, produce effects is fast, and therapeutic effect is comparatively desirable, and is difficult for recurrence.

The present invention for achieving the above object, be achieved through the following technical solutions: a kind of medicine for the treatment of intermingled phlegm and blood stasis type epilepsy, it is made by the raw material of following weight ratio: Radix Gentianae 1-3 gram, Caulis Akebiae 4-6 gram, Radix Bupleuri 6-9 gram, Radix Scutellariae 6-9 gram, Fructus Gardeniae 6-9 gram, Radix Angelicae Sinensis 6-9 gram, Rhizoma Alismatis 12-13 gram, Rhizoma pinelliae cordatae 6-9 gram, Fructus Aurantii Immaturus 6-9 gram, Rhizoma Acori Calami 6-9 gram, Pheretima 6-9 gram, Radix Polygalae 4-6 gram, Radix Astragali 12-13 gram, Radix Codonopsis 12-13 gram, Radix Curcumae 12-13 gram, Radix Salviae Miltiorrhizae 12-13 gram, Semen Persicae 6-9 gram, Flos Carthami 4-6 gram and Rhizoma Chuanxiong 6-9 gram.Described a kind of medicine for the treatment of intermingled phlegm and blood stasis type epilepsy, it is made by following raw material: Radix Gentianae 2 grams, Caulis Akebiae 6 grams, Radix Bupleuri 9 grams, Radix Scutellariae 9 grams, Fructus Gardeniae 9 grams, Radix Angelicae Sinensis 9 grams, Rhizoma Alismatis 12 grams, Rhizoma pinelliae cordatae 9 grams, Fructus Aurantii Immaturus 9 grams, Rhizoma Acori Calami 9 grams, Pheretima 9 grams, Radix Polygalae 6 grams, the Radix Astragali 12 grams, Radix Codonopsis 12 grams, Radix Curcumae 12 grams, Radix Salviae Miltiorrhizae 12 grams, Semen Persicae 9 grams, Flos Carthami 6 grams and Rhizoma Chuanxiong 9 grams.Described a kind of decocting method for the treatment of the medicine of intermingled phlegm and blood stasis type epilepsy, get Radix Gentianae, Caulis Akebiae, Radix Bupleuri, Radix Scutellariae, Fructus Gardeniae, Radix Angelicae Sinensis, Rhizoma Alismatis, Rhizoma pinelliae cordatae, Fructus Aurantii Immaturus, Rhizoma Acori Calami, Pheretima, Radix Polygalae, the Radix Astragali, Radix Codonopsis, Radix Curcumae, Radix Salviae Miltiorrhizae, Semen Persicae, Flos Carthami and Rhizoma Chuanxiong by above-mentioned weight ratio, put into the earth pot of decocting medicinal herbs, add water, exceed raw material plane 2cm to the water surface, 15-30 at a simmer minute, become when water till the medicine soup of buff; Add water again, make the water surface exceed raw material plane 2-3cm, 10-13 at a simmer minute, leach medicine soup and get final product, the medicine soup that is leached is dose.

Wherein Radix Gentianae has the effect of heat clearing away, eliminating pathogen in the liver, arresting convulsion.Caulis Akebiae nature and flavor hardship, cold, pathogenic fire purging row water, promoting blood circulation cures mainly hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.Radix Bupleuri is clearind deficient heat Chinese medicine, is used for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.Radix Scutellariae has heat clearing and damp drying, pathogenic fire purging, and hemostasis, antiabortive, detoxicating functions.Cure mainly hygropyrexia, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, cough due to lung-heat, jaundice due to damp-heat, pneumonia, dysentery, hemoptysis, frequent fetal movement, diseases such as carbuncle furuncle.Fructus Gardeniae has hepatoprotective, function of gallbladder promoting, and calmness, blood pressure lowering, calmness, hemostasis, effects such as detumescence are usually used in treating icterohepatitis at tcm clinical practice, the bruise pain.Radix Angelicae Sinensis cures mainly to enrich blood and invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.The Rhizoma Alismatis theory of Chinese medical science thinks that it is cold in nature, has diuresis, the effect of heat clearing away.Modern medicine study, Rhizoma Alismatis can reduce serum total cholesterol and triacylglycerol content, slow down atherosclerosis and form; Rhizoma Alismatis and preparation modern times thereof are used for the treatment of also that auditory vertigo, hyperlipidemia are unusual, fatty liver and diabetes etc.The Rhizoma Pinelliae has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, reducing swelling and alleviating pain, the effect of detoxicating and fighting cancer.Be mainly used in treatment abundant expectoration cough with asthma, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus; And give birth to external treatment carbuncle sucutaneous nodule.Fructus Aurantii Immaturus stops in curing mainly and stagnating, the feeling of fullness distending pain, and constipation, heavy behind the dysentery, blocked-up chest; Gastroptosis; The uterus proctoptosis, prolapsus.Rhizoma Acori Calami is had one's ideas straightened out, and reduces phlegm, and is good for the stomach.It is vexed to be used for epilepsy, expectorant febrile convulsion, breast abdominal distention; Chronic bronchitis.But Pheretima heat clearing away arresting convulsion, is relievingd asthma diuresis at collateral dredging.Be used for unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema; Vascular hypertension.Radix Polygalae is warm in nature, bitter in the mouth, suffering, has and calms the nerves, and Fructus Alpiniae Oxyphyllae, eliminates the phlegm the repercussive function.The insomnia and dreamful sleep that is used for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.The Radix Astragali has invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, diuresis detumescent, effects such as granulation promoting.Radix Codonopsis has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.But the Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine.But the Radix Salviae Miltiorrhizae promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.But the Semen Persicae blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.But the Flos Carthami promoting blood circulation to restore menstrual flow, the silt pain relieving of loosing is used for amenorrhea, dysmenorrhea, lochia is not all right, the lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.Rhizoma Chuanxiong is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping.Above-mentioned each medicine combination has purging liver-fire, eliminating phlegm and calming wind, and blood circulation promoting and blood stasis dispelling, the effects such as sedate of eliminating the phlegm are mainly used in and treat emotion irritability on ordinary days, vexed insomnia, bitter taste and dryness in the mouth, not well, the constipation of coughing up phlegm, giddiness and downfall with salivation and convulsion during outbreak, or utter a scream; The red tongue tongue is greasy in vain, the stringy and rolling pulse number.Wheezing sound in the throat has headache concurrently, dizziness, and complexion is dark, numb limbs and tense tendons, purplish tongue is dark or diseases such as ecchymosis, hesitant pulse are arranged.Pass on clinical use through three generations people, effect is very remarkable, is difficult for recurrence.

Chinese medicine of the present invention is mainly treated the outbreak of intermingled phlegm and blood stasis type epilepsy, through three generations people's clinical summary, and the symptom of intermingled phlegm and blood stasis type epilepsy: emotion irritability on ordinary days, vexed insomnia, bitter taste and dryness in the mouth, not well, the constipation of coughing up phlegm, giddiness and downfall with salivation and convulsion during outbreak, or utter a scream, the red tongue tongue is greasy in vain, the stringy and rolling pulse number; Wheezing sound in the throat on ordinary days, purplish tongue is dark or ecchymosis is arranged, and convulsion with salivation during morbidity has headache after stopping convulsion, dizziness, complexion is dark, numb limbs and tense tendons, symptoms such as hesitant pulse.Treat 219 examples, male's 121 examples, women's 98 examples, course of disease 4-17 does not wait, and the age minimum is 12 years old, is 57 years old to the maximum.Treatment criterion: 1, cure: the convulsion with salivation transference cure, tracing observation did not recur in 5 years, and EEG (electrocardiogram) examination does not have epilepsy wave; 2, effective: annual minimizing was 1-12 time before a sick number of times was treated.Therapeutic Method: obey potion every day, be decocted in water for oral dose, divide the morning and afternoon to take for twice, be 8-12 hour twice blanking time of taking medicine, 3 months courses of treatment.Clinical statistics is summed up: giddiness and downfall with salivation and convulsion when treatment emotion irritability, vexed insomnia, bitter taste and dryness in the mouth, not well, the constipation of coughing up phlegm, outbreak, scream, have 97 examples, take medicine 1 month the beginning produce effects, tic time decreased during outbreak, take medicine 1-2 the course of treatment effective percentage be 100%, take medicine 3-4 the course of treatment, cure rate is about 99%, consolidates 1 drug withdrawal course of treatment of taking medicine, tracing observation 5 years, 1 routine patient frightened back recurrence, other patients are not recurrence all; Treat wheezing sound in the throat on ordinary days, purplish tongue is dark or ecchymosis is arranged, convulsion with salivation during morbidity, symptoms such as headache, dizziness, complexion are dark, numb limbs and tense tendons, hesitant pulse are arranged after stopping convulsion, have 122 examples, 1 month beginning produce effects of taking medicine, rale alleviates, tic time decreased during morbidity, take medicine 1-2 the course of treatment effective percentage be 100%, take medicine 2-4 the course of treatment, cure rate is 96%, consolidate 1 drug withdrawal course of treatment of taking medicine, tracing observation not recurrence in 5 years.

Model case:

Lee XX, man, 31 years old, the Linqing City people, medical history 11 years, weak and sickly since the childhood, after suffering from the heavy cold healing in 20 years old, find the convulsion with salivation symptom, the hospital diagnosis epilepsy, take the Western medicine disease controlling at ordinary times, but morbidity number of times and disease time increase year by year, by initial annual morbidity 4-6 time, continue 10-20 second, increase to annual 13-15 times, fell ill persistent period 1-2 minute.Diagnose after the inquiring: intermingled phlegm and blood stasis type epilepsy.Take medicament of the present invention and begin produce effects after 1 month, the morbidity persistent period reduces about 30 seconds, take medicine in second phase course of treatment, the secondary of only falling ill half a year, about 30 seconds of persistent period, not morbidity in the 3rd phase course of treatment of taking medicine, EEG (electrocardiogram) examination does not have epilepsy wave after the 3rd expiration course of treatment of taking medicine, consolidate drug withdrawal after 1 course of treatment of taking medicine, tracing observation not recurrence in 5 years.

The specific embodiment

Embodiment:

A kind of raw material for the treatment of the medicine of intermingled phlegm and blood stasis type epilepsy of the present invention can have following multiple weight ratio combination:

1, Radix Gentianae 2 grams, Caulis Akebiae 6 grams, Radix Bupleuri 9 grams, Radix Scutellariae 9 grams, Fructus Gardeniae 9 grams, Radix Angelicae Sinensis 9 grams, Rhizoma Alismatis 12 grams, Rhizoma pinelliae cordatae 9 grams, Fructus Aurantii Immaturus 9 grams, Rhizoma Acori Calami 9 grams, Pheretima 9 grams, Radix Polygalae 6 grams, the Radix Astragali 12 grams, Radix Codonopsis 12 grams, Radix Curcumae 12 grams, Radix Salviae Miltiorrhizae 12 grams, Semen Persicae 9 grams, Flos Carthami 6 grams and Rhizoma Chuanxiong 9 grams.

2, Radix Gentianae 1 gram, Caulis Akebiae 4 grams, Radix Bupleuri 6 grams, Radix Scutellariae 6 grams, Fructus Gardeniae 6 grams, Radix Angelicae Sinensis 6 grams, Rhizoma Alismatis 12 grams, Rhizoma pinelliae cordatae 6 grams, Fructus Aurantii Immaturus 6 grams, Rhizoma Acori Calami 6 grams, Pheretima 6 grams, Radix Polygalae 4 grams, the Radix Astragali 12 grams, Radix Codonopsis 12 grams, Radix Curcumae 12 grams, Radix Salviae Miltiorrhizae 12 grams, Semen Persicae 6 grams, Flos Carthami 4 grams and Rhizoma Chuanxiong 6 grams.

3, Radix Gentianae 3 grams, Caulis Akebiae 6 grams, Radix Bupleuri 9 grams, Radix Scutellariae 9 grams, Fructus Gardeniae 9 grams, Radix Angelicae Sinensis 9 grams, Rhizoma Alismatis 13 grams, Rhizoma pinelliae cordatae 9 grams, Fructus Aurantii Immaturus 9 grams, Rhizoma Acori Calami 9 grams, Pheretima 9 grams, Radix Polygalae 6 grams, the Radix Astragali 13 grams, Radix Codonopsis 13 grams, Radix Curcumae 13 grams, Radix Salviae Miltiorrhizae 13 grams, Semen Persicae 9 grams, Flos Carthami 6 grams and Rhizoma Chuanxiong 9 grams.

4, Radix Gentianae 2 grams, Caulis Akebiae 5 grams, Radix Bupleuri 8 grams, Radix Scutellariae 8 grams, Fructus Gardeniae 8 grams, Radix Angelicae Sinensis 8 grams, Rhizoma Alismatis 12 grams, Rhizoma pinelliae cordatae 8 grams, Fructus Aurantii Immaturus 8 grams, Rhizoma Acori Calami 8 grams, Pheretima 8 grams, Radix Polygalae 5 grams, the Radix Astragali 12 grams, Radix Codonopsis 12 grams, Radix Curcumae 12 grams, Radix Salviae Miltiorrhizae 12 grams, Semen Persicae 8 grams, Flos Carthami 5 grams and Rhizoma Chuanxiong 8 grams.

5, Radix Gentianae 2 grams, Caulis Akebiae 5 grams, Radix Bupleuri 7 grams, Radix Scutellariae 7 grams, Fructus Gardeniae 7 grams, Radix Angelicae Sinensis 7 grams, Rhizoma Alismatis 12 grams, Rhizoma pinelliae cordatae 7 grams, Fructus Aurantii Immaturus 7 grams, Rhizoma Acori Calami 7 grams, Pheretima 7 grams, Radix Polygalae 6 grams, the Radix Astragali 12 grams, Radix Codonopsis 12 grams, Radix Curcumae 12 grams, Radix Salviae Miltiorrhizae 12 grams, Semen Persicae 7 grams, Flos Carthami 6 grams and Rhizoma Chuanxiong 7 grams.

A kind of decocting method for the treatment of the medicine of intermingled phlegm and blood stasis type epilepsy of the present invention: get Radix Gentianae, Caulis Akebiae, Radix Bupleuri, Radix Scutellariae, Fructus Gardeniae, Radix Angelicae Sinensis, Rhizoma Alismatis, Rhizoma pinelliae cordatae, Fructus Aurantii Immaturus, Rhizoma Acori Calami, Pheretima, Radix Polygalae, the Radix Astragali, Radix Codonopsis, Radix Curcumae, Radix Salviae Miltiorrhizae, Semen Persicae, Flos Carthami and Rhizoma Chuanxiong by above-mentioned weight ratio, put into the earth pot of decocting medicinal herbs, add water, exceed raw material plane 2cm to the water surface, 15-30 at a simmer minute, become when water till the medicine soup of buff; Add water again, make the water surface exceed raw material plane 2-3cm, 10-13 at a simmer minute, leach medicine soup and get final product, the medicine soup that is leached is dose.

The present invention not technology contents of detailed description is known technology.

Claims

1. medicine for the treatment of intermingled phlegm and blood stasis type epilepsy, it is characterized in that: it is made by the raw material of following weight ratio: Radix Gentianae 1-3 gram, Caulis Akebiae 4-6 gram, Radix Bupleuri 6-9 gram, Radix Scutellariae 6-9 gram, Fructus Gardeniae 6-9 gram, Radix Angelicae Sinensis 6-9 gram, Rhizoma Alismatis 12-13 gram, Rhizoma pinelliae cordatae 6-9 gram, Fructus Aurantii Immaturus 6-9 gram, Rhizoma Acori Calami 6-9 gram, Pheretima 6-9 gram, Radix Polygalae 4-6 gram, Radix Astragali 12-13 gram, Radix Codonopsis 12-13 gram, Radix Curcumae 12-13 gram, Radix Salviae Miltiorrhizae 12-13 gram, Semen Persicae 6-9 gram, Flos Carthami 4-6 gram and Rhizoma Chuanxiong 6-9 gram.

2. a kind of medicine for the treatment of intermingled phlegm and blood stasis type epilepsy according to claim 1, it is characterized in that: it is made by following raw material: Radix Gentianae 2 grams, Caulis Akebiae 6 grams, Radix Bupleuri 9 grams, Radix Scutellariae 9 grams, Fructus Gardeniae 9 grams, Radix Angelicae Sinensis 9 grams, Rhizoma Alismatis 12 grams, Rhizoma pinelliae cordatae 9 grams, Fructus Aurantii Immaturus 9 grams, Rhizoma Acori Calami 9 grams, Pheretima 9 grams, Radix Polygalae 6 grams, the Radix Astragali 12 grams, Radix Codonopsis 12 grams, Radix Curcumae 12 grams, Radix Salviae Miltiorrhizae 12 grams, Semen Persicae 9 grams, Flos Carthami 6 grams and Rhizoma Chuanxiong 9 grams.

3. a kind of decocting method for the treatment of the medicine of intermingled phlegm and blood stasis type epilepsy according to claim 1, it is characterized in that: get Radix Gentianae, Caulis Akebiae, Radix Bupleuri, Radix Scutellariae, Fructus Gardeniae, Radix Angelicae Sinensis, Rhizoma Alismatis, Rhizoma pinelliae cordatae, Fructus Aurantii Immaturus, Rhizoma Acori Calami, Pheretima, Radix Polygalae, the Radix Astragali, Radix Codonopsis, Radix Curcumae, Radix Salviae Miltiorrhizae, Semen Persicae, Flos Carthami and Rhizoma Chuanxiong by above-mentioned weight ratio, put into the earth pot of decocting medicinal herbs, add water, exceed raw material plane 2cm to the water surface, 15-30 at a simmer minute, become when water till the medicine soup of buff; Add water again, make the water surface exceed raw material plane 2-3cm, 10-13 at a simmer minute, leach medicine soup and get final product, the medicine soup that is leached is dose.