CN103550708B - Chinese herbal compound for treating dysmenorrheal - Google Patents

Chinese herbal compound for treating dysmenorrheal Download PDF

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CN103550708B
CN103550708B CN201310560807.6A CN201310560807A CN103550708B CN 103550708 B CN103550708 B CN 103550708B CN 201310560807 A CN201310560807 A CN 201310560807A CN 103550708 B CN103550708 B CN 103550708B
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dysmenorrhea
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chinese medicine
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宋远慧
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崔合芳
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Abstract

The invention provides a Chinese herbal compound for treating dysmenorrheal and belongs to the technical field of traditional Chinese medicines. The Chinese herbal compound disclosed by the invention is prepared from the following raw medicines in parts by weight: 8-18 parts of angelica sinensis, 4-8 parts of dried tangerine or orange peel, 4-12 parts of the seed of cowherb, 4-8 parts of agilawood, 4-8 parts of rhizoma cyperi, 2-6 parts of golden cypress, 4-12 parts of radix curcumae, 2-6 parts of fructus piperis longi, 2-6 parts of radix angelicae and 12-24 parts of radix bupleuri. The Chinese herbal compound has the characteristics of short course of treatment, remarkable effect, difficult relapse, no toxic or side effects, and solution of root causes of the disease.

Description

A kind of Chinese medicine compound for the treatment of dysmenorrhea
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine compound for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea is one of common gynecological disease, can be divided into primary dysmenorrhea and secondary dysmenorrhea, refers to that women is on the occasion of menstrual period or front and back of passing through, occur periodically lower abdomen pain, or pain draws waist sacrum, with Nausea and vomiting, cold extremities time serious, very then severe pain is fainted, also known as " abdominal pain during menstruation ".
Current treatment dysmenorrhea many employings western medical treatment, western medicine dysmenorrhea many employings analgesia spasmolytic and PGSI, contraceptive, morphine, ibuprofen, ketoprofen, fenamic acids or other potent pain relieving analgesic, though analgesic effect is fast and strong, but curative effect is of short duration, cannot effect a radical cure, through row recurrence.
The traditional Chinese medical science think dysmenorrhea with natural endowment, health, emotion, fatigue, catch cold, the factor such as living habit flip-flop is relevant, sick position in uterus, punching appoints, with " stagnation of QI and blood may bring about pain " or " not flourish and logical " for main pathogenesis.Intermenstrual period is subject to the impact of paathogenic factor, causes punching to appoint stasis blocking or cold accumulating in meridian, and QI-blood circulation is not smooth, and the circulation of uterus menses is obstructed, so that " stagnation of QI and blood may bring about pain "; Or punching is appointed, uterus loses in moistening foster, not flourish and pain.
At present, the Chinese medicine of the treatment dysmenorrhea that market exists, mostly is decoction, takes inconvenience, and lacks just very effective medicine, and therefore, exploitation is a kind of applicable oral, and taking convenience, good effect, treating both the principal and secondary aspects of a disease, have huge Social and economic benef@.
Summary of the invention
The present invention, on the basis of secret prescription handed down in the family from generation to generation, improves through years of researches, and provide a kind of applicable oral, taking convenience, can eliminate fast or relieving dysmenorrhea symptom, treating both the principal and secondary aspects of a disease, treatment cycle is short, the Chinese medicine compound for the treatment of dysmenorrhea evident in efficacy.
Chinese medicine compound of the present invention, comprises the crude drug of following parts by weight: Radix Angelicae Sinensis 8-18 part, Pericarpium Citri Reticulatae 4-8 part, Semen Vaccariae 4-12 part, Lignum Aquilariae Resinatum 4-8 part, Rhizoma Cyperi 4-8 part, Cortex Phellodendri 2-6 part, Radix Curcumae 4-12 part, Fructus Piperis Longi 2-6 part, Radix Angelicae Dahuricae 2-6 part, Radix Bupleuri 12-24 part.
As a further improvement on the present invention, the Chinese medicine compound of described treatment dysmenorrhea comprises the crude drug of following parts by weight: Radix Angelicae Sinensis 12 parts, Pericarpium Citri Reticulatae 4 parts, Semen Vaccariae 6 parts, Lignum Aquilariae Resinatum 6 parts, Rhizoma Cyperi 4 parts, Cortex Phellodendri 2 parts, Radix Curcumae 8 parts, Fructus Piperis Longi 4 parts, the Radix Angelicae Dahuricae 2 parts, Radix Bupleuri 16 parts.
Side of the present invention separates:
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.There is tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, the function of loosening bowel to relieve constipation.Cure mainly all cards of blood deficiency, blood deficiency and blood stasis, menoxenia, amenorrhea, dysmenorrhea, deficient cold type is suffered from abdominal pain, traumatic injury, ulcer sores, wind and cold arthralgia pain, the constipation of blood deficiency dryness of the intestine.
Pericarpium Citri Reticulatae: nature and flavor are bitter, pungent, temperature.Return lung, spleen channel.Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Semen Vaccariae: nature and flavor are bitter is flat.Return liver, stomach warp.Effect promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, lactogenesis of invigorating blood circulation, expedite the emergence of stimulating milk secretion, puerperal thymus dredging.Cure mainly: blood stasis amenorrhea, dysmenorrhea, difficult labour; Lack of lactation after delivery, acute mastitis swells and ache; Pyretic stranguria, stranguria with blood, stranguria caused by urinary stone.
Lignum Aquilariae Resinatum: nature and flavor are pungent, bitter, temperature.Return spleen, stomach, kidney, lung meridian, sending down the abnormal ascending QI warming middle-JIAO, warming the kidney is supporing yang.Cure mainly QI rising in reverse order to pant, vomiting singultus, abdominal distention, waist knee joint cold caused by deficiency, large intestine constipation due to insufficiency, urine qi stranguria, man's cold sperm.
Rhizoma Cyperi: pungent, sweet, micro-hardship, flat.Return liver, tri-jiao channel.There is dispersing the stagnated live-QI to relieve the stagnation of QI, menstruction regulating and pain relieving, the function of regulating the flow of Qi and the middle Jiao.Menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Stagnation of QI due to depression of the liver hypochondriac pain, stomachache, menoxenia, dysmenorrhea, distending pain of the breast, abdominal pain due to stagnation of QI.
Cortex Phellodendri: nature and flavor are bitter, cold.Return kidney, bladder, large intestine channel.Function with cure mainly: heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian, there is the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire.
Fructus Piperis Longi: nature and flavor: pungent, heat.Return spleen channel, stomach warp, large intestine channel, lung meridian, urinary bladder channel, Liver Channel, kidney channel.
Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.Cure mainly: for coldness and pain in the epigastrium, vomit, have loose bowels, the toothache of migraine, nasal sinusitis, external treatment, coronary heart diseases and angina pectoris.Control trusted subordinate's cold type of pain, vomiting acid regurgitation, increased borborygmus and diarrhea, cold-dysentery, scrotal hernia, headache, nasal sinusitis, toothache.
The Radix Angelicae Dahuricae: property is pungent, temperature.Enter lung, spleen, stomach warp.Attending effectiveness: expelling wind and removing dampness; Logical surreptitiously pain relieving; Detumescence and apocenosis.Main headache due to common cold; Supraorbital bone pain; Toothache; Nasal obstruction; Nasal sinusitis; Domination of damp pathogen chronic diarrhea; Women leucorrhea; Ulcer sores; Venom.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Radix Bupleuri: bitter, is slightly cold.Return liver, gallbladder meridian.Meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, gallbladder meridian, tool depressed liver-energy dispersing and function of gallbladder promoting, dredge gas resolving depression, loose effect of fire.Expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly: the heating that cures cold, cold and heat deficient fever.Children's's varioliform exanthema waste heat, emaciation and sallow complexion abdominal part expands, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, and uterus comes off, menoxenia.
The preparation process that the present invention treats dysmenorrhea Chinese medicine compound is simple, without the need to by water extraction and alcohol extraction process, is directly pulverized and mixed evenly preparation process routinely and prepares.Preferably, clinical acceptable peroral dosage form can be made by preparation process routinely.
Described peroral dosage form is tablet, granule, capsule, soft capsule, pill.
Be preferably capsule.
As a further improvement on the present invention, the invention provides a kind of preparation method for the treatment of the Herbal compound capsule agent of dysmenorrhea as follows: take each crude drug raw medicinal material by parts by weight proportioning of the present invention and clean, dry; Pulverize, cross 80 mesh sieves, insert No. 0 capsule, to obtain final product.
In crude drug of the present invention, Radix Angelicae Sinensis, Semen Vaccariae blood circulation promoting and blood stasis dispelling, promoting the circulation of blood regulating menstruation, can be monarch drug; Pericarpium Citri Reticulatae, Rhizoma Cyperi, Fructus Piperis Longi, Radix Curcumae promoting QI circulation for relieving depression, menstruction regulating and pain relieving can be ministerial drug; All medicines such as all the other Radix Bupleuri, Cortex Phellodendris etc. are adjuvant, and all medicines are harmonious, and play promoting blood circulation, removing blood stasis and relieving pain altogether, have no side effect, and can fast and effeciently eliminate or relieving dysmenorrhea symptom, can be used for treating dysmenorrhea.In addition, Chinese medicine composition of the present invention, dosage is few, and stimulate little to the intestines and stomach, entered clinical experiment proved invention compound of Chinese medicine dysmenorrhea for many years, total effective rate can reach more than 95%, and cure rate can reach more than 60%, and all cases all have no adverse reaction.
clinical observation and model case: the clinical observation on the therapeutic effect experiment of compound of Chinese medicine dysmenorrhea patient of the present invention.
1. physical data
The present inventor in 2011 so far, carries out clinical observation treatment to 210 routine dysmenorrhea patients.Wherein age reckling 14 years old, the maximum 46 years old, 24 years old mean age; Wherein without sexual life person 145 example, sexual intercourse person 65 example; The course of disease 2 months ~ 5 years, average (2 ± 1.8) year.This group case is made a definite diagnosis through gynecologial examination and/or B ultrasonic, gets rid of the mechanical injuries of reproductive system organs in pelvic cavity.
2. Therapeutic Method
Usage and dosage: adopt the granule prepared by the embodiment of the present invention 1, its usage and consumption are each l bag, 5 grams every bag, and every day 2 times, warm water takes, one after each meal, one month are a course for the treatment of, treat for 2 courses for the treatment of altogether.
3. efficacy assessment standard
The present invention is used for the treatment of dysmenorrhea disease, and " Chinese medical disease Standardization of diagnosis and curative effect " that its criterion of therapeutical effect is issued with reference to State Administration of Traditional Chinese Medicine is formulated, and is divided into following three kinds:
Cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.
Take a turn for the better: pain relief or pain disappear, but can not maintain more than 3 months.
Do not heal: pain has no improvement.
4. therapeutic effect
In accepted for medical treatment 210 routine cases, through treatment in 2 months, wherein cure 138 examples, cure rate 65.7%, take a turn for the better: 62 examples, invalid 12 examples, total effective rate reaches 95.2%.Result shows, Chinese medicine composition of the present invention effectively can treat dysmenorrhea, and effect is extremely remarkable.
Compared with prior art, the invention has the beneficial effects as follows: we have short treating period, Be very effective, not easily recur, have no side effect, given full play to its treating both the principal and secondary aspects of a disease of the traditional Chinese medical science, the feature of digging up the roots of curing the disease.And traditional Chinese medicine composite of the present invention is easy to get, preparation process thereof is simple, and low in treatment cost, can alleviate the advantages such as the financial burden of patient.
5. model case
L, Qiu so-and-so, 18 years old, private prosecution in May, 2012, patient started each intermenstrual period lower abdomen pain before 1 year, pain very time companion nausea and vomiting, can not adhere to normally attending class.Look into: dimly red tongue, white and thin fur, stringy and tense pulse.Through gynecologial examination, after getting rid of the mechanical injuries of reproductive system organs in pelvic cavity, give granule of the present invention, take 2 courses for the treatment of continuously, the eumenorrhea, pain disappears, and follows up a case by regular visits to have no and do not recur after half a year.
2, Sui so-and-so, 26 years old, private prosecution in May, 2010, patient's i.e. dysmenorrhea after menstrual onset before 3 years, unbearably, even need to take analgesic, menstruation color secretly held block under the arm to each menstrual pain.Through gynecologial examination, after getting rid of the mechanical injuries of reproductive system organs in pelvic cavity, give granule of the present invention, take 2 courses for the treatment of continuously, the eumenorrhea, pain disappears, and follows up a case by regular visits to have no and do not recur after half a year.
3, Lee so-and-so, 35 years old, married.During nearly menstrual onset over the past half year, lower abdomen hurt like hell, the companion whole body is weak, and lower abdomen falling inflation is obvious, and many through measuring, color is dark red block.Ultrasound diagnosis is shown: left side attachment is shown in inflammatory mass.Examine as chronic pelvic inflammatory disease.Give granule of the present invention, take 2 courses for the treatment of continuously, the eumenorrhea, inflammation disappears, and pain disappears, and follows up a case by regular visits to have no and do not recur after half a year.
Detailed description of the invention
Now in conjunction with concrete preferred implementation further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, some simple deduction or replace can also be made, all should be considered as belonging to protection scope of the present invention.
EXAMPLE l: weighting raw materials material Radix Angelicae Sinensis 1200g, Pericarpium Citri Reticulatae 400g, Semen Vaccariae 600g, Lignum Aquilariae Resinatum 600g, Rhizoma Cyperi 400g, Cortex Phellodendri 200g, Radix Curcumae 800g, Fructus Piperis Longi 400g, Radix Angelicae Dahuricae 200g, Radix Bupleuri 1600g; Clean, dry, pulverize, cross 80 mesh sieves, obtain granule, then insert No. 0 capsule, every fills 0. 4g, obtains capsule of the present invention.
Embodiment 2: weighting raw materials material Radix Angelicae Sinensis 1800g, Pericarpium Citri Reticulatae 800g, Semen Vaccariae 1200g, Lignum Aquilariae Resinatum 800g, Rhizoma Cyperi 800g, Cortex Phellodendri 600g, Radix Curcumae 800g, Fructus Piperis Longi 400g, Radix Angelicae Dahuricae 200g, Radix Bupleuri 1600g; Clean, dry, pulverize, cross 80 mesh sieves, then insert No. 0 capsule, every fills 0. 4g, obtains capsule of the present invention.
Embodiment 3: weighting raw materials material Radix Angelicae Sinensis 1000g, Pericarpium Citri Reticulatae 600g, Semen Vaccariae 600g, Lignum Aquilariae Resinatum 800g, Rhizoma Cyperi 800g, Cortex Phellodendri 600g, Radix Curcumae 1200g, Fructus Piperis Longi 400g, Radix Angelicae Dahuricae 600g, Radix Bupleuri 2000g; Clean, dry, pulverize, cross 80 mesh sieves, then insert No. 0 capsule, every fills 0. 4g, obtains capsule of the present invention.

Claims (3)

1. treat a Chinese medicine composition for dysmenorrhea, it is characterized in that being made up of the raw material of following weight portion: Radix Angelicae Sinensis 12 parts, Pericarpium Citri Reticulatae 4 parts, Semen Vaccariae 6 parts, Lignum Aquilariae Resinatum 6 parts, Rhizoma Cyperi 4 parts, Cortex Phellodendri 2 parts, Radix Curcumae 8 parts, Fructus Piperis Longi 4 parts, the Radix Angelicae Dahuricae 2 parts, Radix Bupleuri 16 parts.
2. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 1, is characterized in that: described Chinese medicine composition is peroral dosage form.
3. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 2, is characterized in that: described peroral dosage form is capsule.
CN201310560807.6A 2013-11-13 2013-11-13 Chinese herbal compound for treating dysmenorrheal Active CN103550708B (en)

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CN104258303A (en) * 2014-10-09 2015-01-07 夏美娜 Traditional Chinese medicine for treating dysmenorrhea
CN107496832A (en) * 2017-08-31 2017-12-22 海南娜古芳沉香科技有限公司 A kind of composition for alleviating dysmenorrhoea and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101077403A (en) * 2007-05-05 2007-11-28 赵启坤 Plaster for treating retention of food and dysmenorrhea
CN101869691A (en) * 2010-06-30 2010-10-27 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating dysmenorrhea and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101077403A (en) * 2007-05-05 2007-11-28 赵启坤 Plaster for treating retention of food and dysmenorrhea
CN101869691A (en) * 2010-06-30 2010-10-27 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating dysmenorrhea and preparation method thereof

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