CN104258303A - Traditional Chinese medicine for treating dysmenorrhea - Google Patents
Traditional Chinese medicine for treating dysmenorrhea Download PDFInfo
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- CN104258303A CN104258303A CN201410553304.0A CN201410553304A CN104258303A CN 104258303 A CN104258303 A CN 104258303A CN 201410553304 A CN201410553304 A CN 201410553304A CN 104258303 A CN104258303 A CN 104258303A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/738—Rosa (rose)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/756—Phellodendron, e.g. corktree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
Abstract
The invention relates to the field of traditional Chinese medicine formulae and in particular to a traditional Chinese medicine for treating dysmenorrhea. The traditional Chinese medicine is characterized by being prepared from the following raw materials in parts by weight: 15-20 parts of radix bupleuri, 10-15 parts of monthly rose root, 8-12 parts of silene conoidea, 10-12 parts of membranaceous beautyleaf root, 10-15 parts of damnacanthus indicus, 6-10 parts of curcuma aromatica, 20-25 parts of sticktight, 6-8 parts of rhizoma sparganii, 10-12 parts of mistletoe, 12-15 parts of centipeda minima, 15-20 parts of striga asiatica, 8-10 parts of achyranthes aspera, 12-16 parts of lindley eupatorium, 6-10 parts of cucurbita moschata duch, 15-20 parts of piper cubeba, 11-13 parts of salvia prionitis, 12-14 parts of uncaria rhynchophylla, 15-18 parts of cortex phellodendri, 9-12 parts of dark plum, 10-14 parts of dandelion, 14-18 parts of caulis perllae, 16-18 parts of cassia twig and 12-16 parts of selfheal. The raw materials are soaked with water, decocted and subjected to residue removal to obtain filter liquor. According to the traditional Chinese medicine, the treatment effect is improved and the problems of non treatment of both symptoms and root causes due to the use of chemical pharmaceutical preparations and weakening of the treatment effect due to reduced drug sensitivity of patients easily caused by long-time drug use are solved.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine being used for the treatment of dysmenorrhea.
Background technology
As everyone knows, dysmenorrhea, is commonly encountered diseases and the frequently-occurring disease of gynecological, belongs to endocrine disturbance, is there is periodically lower abdomen pain between menstrual period or before and after row, or pain draw waist sacrum even severe pain faint for the menstruation class disease of main manifestations.The dysmenorrhea incidence rate of China women is about 3.1%, and dysmenorrhea is sent out with menstrual cycle, and severe patient can accompany nausea and vomiting, dripping cold sweat, deadly cold hand and foot even to faint, and brings have a strong impact on to routine work, study and life.At present, clinically for the treatment of dysmenorrhea still based on oral western medicine.Not only there is liver first-pass effect and GI irritation in oral western medicine, also increased the weight of patient's Liver and kidney burden, the drug effect persistent period is also short.External treatment of tcm is one of Therapeutic Method of Chinese medicine traditional special effects, and have the double treatment effect of percutaneous drug absorption and stimulation meridian point, evident in efficacy, side effect is low, and easy to use.But Traditional transdermal form of administration is as black plaster, rubber paste etc., also exist serious drawback is as little in drug loading, Drug Percutaneous Absorption efficiency is low, stronger skin irritation and anaphylaxis, airtight, take off from time pull off the feather of and produce pain etc. and patient is not easily accepted.
Summary of the invention
Object of the present invention is exactly to overcome above-mentioned existing technical deficiency, a kind of Chinese medicine being used for the treatment of dysmenorrhea is provided, according to the rule for the treatment of prescription of " dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, enrich and benefit essence and blood ", cost is low, improve therapeutic effect, solve use chemicals medicine to cure the symptoms, not the disease, long-time medication is easy to cause patient reduce the sensitivity of medicine and weaken the problem of curative effect.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine being used for the treatment of dysmenorrhea, it is characterized in that being made up of the crude drug of following weight portion, Radix Bupleuri 15 ~ 20, Radix Rosae Chinensis 10 ~ 15, Herba Silenes conoideae 8 ~ 12, Radix calophylli membranacei 10 ~ 12, Herba Damnacanthi 10 ~ 15, Radix Curcumae 6 ~ 10, Herba Bidentis Bipinnatae 20 ~ 25, Rhizoma Sparganii 6 ~ 8, Herba Visci 10 ~ 12, Herba Centipedae 12 ~ 15, Herba Lobeliae Chinensis 15 ~ 20, Radix achyranthis asperae (Herba Achyranthis Asperae) 8 ~ 10, Herba Eupatorii Lindleyani 12 ~ 16, Pedicellus Cucurbitae 6 ~ 10, Fructus Litseae 15 ~ 20, Arisaema balansae Engl. grass 11 ~ 13, Ramulus Uncariae Cum Uncis 12 ~ 14, Cortex Phellodendri 15 ~ 18, Fructus Mume 9 ~ 12, Herba Taraxaci 10 ~ 14, Caulis Perillae 14 ~ 18, Ramulus Cinnamomi 16 ~ 18, Spica Prunellae 12 ~ 16, by medicinal for above-mentioned raw materials water soaking, to remove slag after decocting to obtain filtrate.
The present invention is according to the rule for the treatment of prescription of " dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, enrich and benefit essence and blood ", cost is low, improve therapeutic effect, solve use chemicals medicine to cure the symptoms, not the disease, long-time medication is easy to cause patient reduce the sensitivity of medicine and weaken the problem of curative effect.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
The present embodiment uses the crude drug of following weight proportion for a dose of medicine: Radix Bupleuri 18 grams, Radix Rosae Chinensis 12 grams, Herba Silenes conoideae 10 grams, Radix calophylli membranacei 11 grams, Herba Damnacanthi 12 grams, Radix Curcumae 8 grams, Herba Bidentis Bipinnatae 22 grams, Rhizoma Sparganii 7 grams, Herba Visci 11 grams, Herba Centipedae 13 grams, Herba Lobeliae Chinensis 12 grams, Radix achyranthis asperae (Herba Achyranthis Asperae) 9 grams, Herba Eupatorii Lindleyani 14 grams, Pedicellus Cucurbitae 8 grams, Fructus Litseae 17 grams, Arisaema balansae Engl. grass 12 grams, Ramulus Uncariae Cum Uncis 13 grams, Cortex Phellodendri 16 grams, Fructus Mume 10 grams, Herba Taraxaci 12 grams, Caulis Perillae 16 grams, Ramulus Cinnamomi 17 grams, Spica Prunellae 14 grams, get above-mentioned 23 taste herbal raw materials, gross weight is 202 grams, add water 1100 ~ 1300ml, soak 2 ~ 3 hours, then boil with high heat, slow fire decocts 60 ~ 70 minutes, remove slag to obtain filtrate about 200ml, medicinal residues add water 300 ~ 400ml again, decoct about 30 minutes, remove slag to obtain filtrate about 100ml, be total to obtain about 300ml medicine juice, load in sterile glass vials, seal bottle cap is for subsequent use.Every day 1 dose point 2 times is oral, each (medicine) being taken before meal about 150ml.
Radix Bupleuri of the present invention has reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia; Radix Rosae Chinensis has promoting blood flow to regulate menstruation, dispersing swelling and dissipating binds, relieving leukorrhea by astringents.Main menoxenia, dysmenorrhea, amenorrhea, metrorrhagia, traumatic injury, scrofula, seminal emission effect; Herba Silenes conoideae clearing away heat and cooling blood, blood-arresting catamenia-regulating.For epistaxis, spit blood, hematuria, lung abscess, menoxenia, three tastes are monarch drug altogether; Radix calophylli membranacei is used for rheumatic arthritis, lumbago and skelalgia, traumatic injury, icterohepatitis, menoxenia, dysmenorrhea; Herba Damnacanthi expelling wind and removing dampness, promoting blood circulation and detumescence.Control gout, rheumatic arthralgia.Cough due to fluid-retention, lung abscess, edema, mass in the abdomen, jaundice, women's amenorrhea, infantile malnutrition, urticaria, traumatic injury, two tastes help monarch, are ministerial drug altogether; Assistant is with Radix Curcumae, Herba Bidentis Bipinnatae, and Radix Curcumae has the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire; Herba Bidentis Bipinnatae has effect of heat-clearing and toxic substances removing, removing blood stasis and activating blood flow; Rhizoma Sparganii controls lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the side of body, and swollen pain, amenorrhea, postnatal blood stasis stomachache, traumatic injury, skin ulcer swell hard down; Herba Visci has relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation to remove blood stasis.For bones and muscles pain, limbs contracture, aching pain in waist and back.Invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, the effect such as antiabortive; Herba Centipedae dispersing wind-cold, clearing the nasal passage, cough-relieving, removing toxic substances, antipruritic; Herba Lobeliae Chinensis heat clearing away, removing food stagnancy.For infantile malnutrition, Infantile Summer Fever, infantile diarrhea, icterohepatitis; Radix achyranthis asperae (Herba Achyranthis Asperae) heat clearing away, induces sweat, and diuretic is invigorated blood circulation.Cure mainly: cold, fever, dysentery, malaria, laryngalgia, beriberi, gonorrhea.Edema, traumatic injury; Herba Eupatorii Lindleyani cures mainly: don't lung cough-relieving, resolving phlegm and relieving asthma, blood pressure lowering.Main bronchus is scorching, cough with copious phlegm, hypertension; Pedicellus Cucurbitae detoxifies, and diuretic is antiabortive.Main swollen ulcer drug, furuncle, scalds, the sore being festered and unhealed, edema ascites, frequent fetal movement; Fructus Litseae warming the spleen and kidney, invigorating the stomach and promoting digestion; Arisaema balansae Engl. grass falls apart wind heat, throat.For cold, fever, acute tonsillitis, pneumonia, enteritis, diarrhea, stomachache, dysentery; Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control pediatric epilepsy scared Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclamposia; Cortex Phellodendri heat clearing away.Dampness, pathogenic fire purging, removing toxic substances.Control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice, flaccidity is knitted, nocturnal emission, stranguria with turbid discharge, and hemorrhoid, have blood in stool, leucorrhea with red and white discharge; Fructus Mume is astringed the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, deficiency-heat excessive thirst, chronic malaria, chronic diarrhea; Herba Taraxaci has the several functions such as heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, antiinflammatory, removing heat from blood, diuresis, function of gallbladder promoting, hypocatharsis, stomach invigorating, anti-cancer; Caulis Perillae has regulating the flow of QI to ease the stomach, dispelling dampness and promoting diuresis, promoting the circulation of QI to relieve pain.Be usually used in chest and diaphragm painful abdominal mass vexed, gastralgia, belch is vomitted, the situations such as frequent fetal movement; Effect of Ramulus Cinnamomi complement sun, promoting blood circulation, warming the spleen and stomach; Spica Prunellae liver heat removing, eliminating stagnation, diuresis; Control the diseases such as pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension, altogether for making medicine.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize, and its processing method is identical with embodiment one.
The clinical trial carried out below in conjunction with my institute is done further the present invention, is described in detail:
1, case selection: according to " tcm clinical practice Illnesses Diagnoses criterion of therapeutical effect ", clinical main manifestations be menstrual period or through after lower abdomen pain on the one, two or lower abdomen and pudendum sky pendant, swollen sense, likes warm pain relieved by pressing, Hypomenorrhea, the light matter of color is thin, or spiritlessness and weakness, or lustreless complexion, or anorexia loose stool, pale tongue, thready and weak pulse.Wherein cardinal symptom is indispensable, has more than 2 simultaneous phenomenons, and gynaecological examination (anus is looked into) or B ultrasonic etc. are got rid of positive pathological changes and can be made a definite diagnosis.68 routine dysmenorrhea patients, 14 ~ 27 years old 56 age example, 28 ~ 36 years old 12 example; 44 examples in the course of disease 1 year, 1 ~ 3 year 15 example, 4 ~ 6 years 9 examples.
2, Therapeutic Method:
Every day 1 dose point 2 times is oral, and each (medicine) being taken before meal about 150ml, uses 7 days continuously.
3, efficacy evaluation: " the Chinese medical disease Standardization of diagnosis and curative effect " promulgated with reference to State Administration of Traditional Chinese Medicine carries out therapeutic evaluation: 1. cure: pain disappears, and continuous 3 menstrual cycle have no recurrence; 2. take a turn for the better: pain relief or disappearance, but can not more than 3 months be maintained; 3. invalid: pain has no improvement.
4, therapeutic effect: cure 60 examples, account for 88.24%; Take a turn for the better 8 examples, accounts for 11.76%; Total effective rate 100%, and in use there is not untoward reaction in the present invention.
Model case:
Yellow XX, female, 17 years old, menstruation rule usually, 28 ~ 32 days cycles, in 5 ~ 7 days menstrual period, in amount, color is dark red, folder clot, and each menstrual onset all occurs hypogastralgia in the 1st, 2 days, even faint, the nauseating sweating of companion, takes Chinese medicine composition provided by the invention after 4 days, transference cure continuously.
Grandson X, 29 years old, excessive melancholy and psychentonia caused concentrated expression in menstrual period, and pain is spastic, paroxysmal, pale complexion, be in a cold sweat, general weakness, extremity fault be cold.Nausea and vomiting, take Chinese medicine composition provided by the invention continuously after 4 days, symptom all disappears.
Song XX, 32 years old, there is lower abdomen spasmic pain menstrual period in female, simultaneously with pale complexion, be in a cold sweat, the symptom such as headache, take Chinese medicine composition provided by the invention continuously after 6 days, symptom all disappears.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of dysmenorrhea, it is characterized in that being made up of the crude drug of following weight portion, Radix Bupleuri 15 ~ 20, Radix Rosae Chinensis 10 ~ 15, Herba Silenes conoideae 8 ~ 12, Radix calophylli membranacei 10 ~ 12, Herba Damnacanthi 10 ~ 15, Radix Curcumae 6 ~ 10, Herba Bidentis Bipinnatae 20 ~ 25, Rhizoma Sparganii 6 ~ 8, Herba Visci 10 ~ 12, Herba Centipedae 12 ~ 15, Herba Lobeliae Chinensis 15 ~ 20, Radix achyranthis asperae (Herba Achyranthis Asperae) 8 ~ 10, Herba Eupatorii Lindleyani 12 ~ 16, Pedicellus Cucurbitae 6 ~ 10, Fructus Litseae 15 ~ 20, Arisaema balansae Engl. grass 11 ~ 13, Ramulus Uncariae Cum Uncis 12 ~ 14, Cortex Phellodendri 15 ~ 18, Fructus Mume 9 ~ 12, Herba Taraxaci 10 ~ 14, Caulis Perillae 14 ~ 18, Ramulus Cinnamomi 16 ~ 18, Spica Prunellae 12 ~ 16, by medicinal for above-mentioned raw materials water soaking, to remove slag after decocting to obtain filtrate.
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CN105853632A (en) * | 2016-04-20 | 2016-08-17 | 朱正梅 | Traditional Chinese medicine for treating dysmenorrhea |
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US20080113049A1 (en) * | 2006-03-30 | 2008-05-15 | Yangsen Biotechnology Co., Ltd. | Compositions and methods for uterine relaxing |
CN103550708A (en) * | 2013-11-13 | 2014-02-05 | 崔合芳 | Chinese herbal compound for treating dysmenorrheal |
CN103638133A (en) * | 2013-11-26 | 2014-03-19 | 隗存富 | Traditional Chinese medicine formula for treating dysmenorrhoea |
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