CN102239261A - 人工染色体载体 - Google Patents
人工染色体载体 Download PDFInfo
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- CN102239261A CN102239261A CN2009801478450A CN200980147845A CN102239261A CN 102239261 A CN102239261 A CN 102239261A CN 2009801478450 A CN2009801478450 A CN 2009801478450A CN 200980147845 A CN200980147845 A CN 200980147845A CN 102239261 A CN102239261 A CN 102239261A
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2800/00—Nucleic acids vectors
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Abstract
Description
Claims (15)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710073136.9A CN107012168A (zh) | 2008-11-28 | 2009-11-18 | 人工染色体载体 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT18592008 | 2008-11-28 | ||
ATA1859/2008 | 2008-11-28 | ||
PCT/EP2009/065410 WO2010060844A1 (en) | 2008-11-28 | 2009-11-18 | Artificial chromosome vector |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710073136.9A Division CN107012168A (zh) | 2008-11-28 | 2009-11-18 | 人工染色体载体 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN102239261A true CN102239261A (zh) | 2011-11-09 |
Family
ID=41594656
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710073136.9A Pending CN107012168A (zh) | 2008-11-28 | 2009-11-18 | 人工染色体载体 |
CN2009801478450A Pending CN102239261A (zh) | 2008-11-28 | 2009-11-18 | 人工染色体载体 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710073136.9A Pending CN107012168A (zh) | 2008-11-28 | 2009-11-18 | 人工染色体载体 |
Country Status (12)
Country | Link |
---|---|
US (1) | US8647841B2 (zh) |
EP (2) | EP3372687B1 (zh) |
JP (1) | JP5791508B2 (zh) |
KR (1) | KR101728079B1 (zh) |
CN (2) | CN107012168A (zh) |
CA (1) | CA2744976C (zh) |
DK (1) | DK2356241T3 (zh) |
EA (1) | EA020311B1 (zh) |
ES (1) | ES2687447T3 (zh) |
PL (1) | PL2356241T3 (zh) |
SG (1) | SG171837A1 (zh) |
WO (1) | WO2010060844A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105087632A (zh) * | 2015-09-07 | 2015-11-25 | 清华大学 | 一种酿酒酵母染色体及其构建方法与应用 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019530737A (ja) | 2016-08-23 | 2019-10-24 | アコーオス インコーポレイテッド | ヒト対象において非加齢性聴力障害を治療するための組成物および方法 |
WO2019086694A1 (en) | 2017-11-06 | 2019-05-09 | Geert Mudde | Il31 antigen and vaccine |
AU2021225035A1 (en) | 2020-02-21 | 2022-10-13 | Akouos, Inc. | Compositions and methods for treating non-age-associated hearing impairment in a human subject |
KR102384173B1 (ko) * | 2020-05-22 | 2022-04-06 | 인천대학교 산학협력단 | 박테리아 인공 염색체 재조합 스크리닝 방법 |
Citations (3)
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WO2002096923A1 (en) * | 2001-05-30 | 2002-12-05 | Chromos Molecular Systems, Inc. | Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes |
WO2002097059A2 (en) * | 2001-05-30 | 2002-12-05 | Chromos Molecular Systems, Inc. | Chromosome-based platforms |
WO2004056986A2 (en) * | 2002-12-20 | 2004-07-08 | Chromagenics B.V. | Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001283377B2 (en) * | 2000-08-14 | 2007-09-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced homologous recombination mediated by lambda recombination proteins |
EP2138583A1 (en) * | 2000-12-22 | 2009-12-30 | Institut National De La Recherche Agronomique | Position-independent and tissue specific expression of a transgene in milk of transgenic animals |
CA2449303C (en) * | 2001-06-06 | 2014-10-14 | Regeneron Pharmaceuticals, Inc. | Method for targeting transcriptionally active loci |
AU2003257155A1 (en) * | 2002-08-02 | 2004-02-23 | The General Hospital Corporation | Methods for the production of cells and mammals with desired genetic modifications |
CN1717483A (zh) * | 2002-10-04 | 2006-01-04 | 麒麟麦酒株式会社 | 人类人工染色体(hac)载体 |
EP1439234A1 (en) * | 2003-01-08 | 2004-07-21 | ARTEMIS Pharmaceuticals GmbH | Targeted transgenesis using the rosa26 locus |
KR20060002745A (ko) * | 2003-01-13 | 2006-01-09 | 마헨드라 에스 라오 | 치료적 생성물의 전달을 위한 증식성 줄기세포 및전구세포에서의 후보 분자의 지속적 발현 |
BRPI0507934A (pt) * | 2004-02-23 | 2007-07-17 | Chromatin Inc | plantas modificadas com mini-cromossomas |
EP1614755A1 (en) * | 2004-07-07 | 2006-01-11 | ARTEMIS Pharmaceuticals GmbH | Target transgenesis of short hairpin RNA expression cassette using recombinase mediated cassette exchange |
TW200817512A (en) * | 2006-07-07 | 2008-04-16 | Kirin Pharma Kk | Human artificial chromosome (hac) vector, and human cell pharmaceutical comprising human artificial chromosome (hac) vector |
AU2008205459A1 (en) * | 2007-01-19 | 2008-07-24 | Mount Sinai School Of Medicine Of New York University | Stem cell gene targeting |
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2009
- 2009-11-18 EA EA201170505A patent/EA020311B1/ru not_active IP Right Cessation
- 2009-11-18 US US13/130,478 patent/US8647841B2/en active Active
- 2009-11-18 DK DK09756728.3T patent/DK2356241T3/en active
- 2009-11-18 ES ES09756728.3T patent/ES2687447T3/es active Active
- 2009-11-18 CN CN201710073136.9A patent/CN107012168A/zh active Pending
- 2009-11-18 JP JP2011537935A patent/JP5791508B2/ja active Active
- 2009-11-18 EP EP18164934.4A patent/EP3372687B1/en active Active
- 2009-11-18 EP EP09756728.3A patent/EP2356241B1/en active Active
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- 2009-11-18 WO PCT/EP2009/065410 patent/WO2010060844A1/en active Application Filing
- 2009-11-18 PL PL09756728T patent/PL2356241T3/pl unknown
- 2009-11-18 CN CN2009801478450A patent/CN102239261A/zh active Pending
- 2009-11-18 KR KR1020117011056A patent/KR101728079B1/ko active IP Right Grant
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002096923A1 (en) * | 2001-05-30 | 2002-12-05 | Chromos Molecular Systems, Inc. | Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes |
WO2002097059A2 (en) * | 2001-05-30 | 2002-12-05 | Chromos Molecular Systems, Inc. | Chromosome-based platforms |
WO2004056986A2 (en) * | 2002-12-20 | 2004-07-08 | Chromagenics B.V. | Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors |
Non-Patent Citations (3)
Title |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105087632A (zh) * | 2015-09-07 | 2015-11-25 | 清华大学 | 一种酿酒酵母染色体及其构建方法与应用 |
CN105087632B (zh) * | 2015-09-07 | 2019-12-10 | 清华大学 | 一种酿酒酵母染色体及其构建方法与应用 |
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DK2356241T3 (en) | 2018-09-17 |
ES2687447T3 (es) | 2018-10-25 |
PL2356241T3 (pl) | 2018-12-31 |
KR20110091675A (ko) | 2011-08-12 |
WO2010060844A1 (en) | 2010-06-03 |
US8647841B2 (en) | 2014-02-11 |
CA2744976A1 (en) | 2010-06-03 |
EP3372687B1 (en) | 2022-01-12 |
SG171837A1 (en) | 2011-07-28 |
EA201170505A1 (ru) | 2011-12-30 |
JP5791508B2 (ja) | 2015-10-07 |
EP2356241B1 (en) | 2018-06-20 |
CN107012168A (zh) | 2017-08-04 |
US20110229932A1 (en) | 2011-09-22 |
EP3372687A1 (en) | 2018-09-12 |
CA2744976C (en) | 2017-09-12 |
JP2012511307A (ja) | 2012-05-24 |
EA020311B1 (ru) | 2014-10-30 |
EP2356241A1 (en) | 2011-08-17 |
KR101728079B1 (ko) | 2017-04-18 |
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