CN102228469A - 一种纳米硒颗粒及其制备方法 - Google Patents
一种纳米硒颗粒及其制备方法 Download PDFInfo
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- CN102228469A CN102228469A CN 201110151696 CN201110151696A CN102228469A CN 102228469 A CN102228469 A CN 102228469A CN 201110151696 CN201110151696 CN 201110151696 CN 201110151696 A CN201110151696 A CN 201110151696A CN 102228469 A CN102228469 A CN 102228469A
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- selenium
- nano granules
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- 229910052711 selenium Inorganic materials 0.000 title claims abstract description 41
- 239000011669 selenium Substances 0.000 title claims abstract description 41
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 239000002245 particle Substances 0.000 title abstract 4
- 229940091258 selenium supplement Drugs 0.000 claims abstract description 40
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 37
- 238000000034 method Methods 0.000 claims abstract description 14
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 claims abstract description 10
- 102000001554 Hemoglobins Human genes 0.000 claims abstract description 10
- 108010054147 Hemoglobins Proteins 0.000 claims abstract description 10
- 235000017471 coenzyme Q10 Nutrition 0.000 claims abstract description 10
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 claims abstract description 10
- 229940110767 coenzyme Q10 Drugs 0.000 claims abstract description 10
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims abstract description 9
- 229960001471 sodium selenite Drugs 0.000 claims abstract description 9
- 235000015921 sodium selenite Nutrition 0.000 claims abstract description 9
- 239000011781 sodium selenite Substances 0.000 claims abstract description 9
- 238000001035 drying Methods 0.000 claims abstract description 5
- 239000008187 granular material Substances 0.000 claims description 27
- 239000000203 mixture Substances 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000008367 deionised water Substances 0.000 claims description 6
- 229910021641 deionized water Inorganic materials 0.000 claims description 6
- 230000036039 immunity Effects 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 abstract description 2
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 230000007365 immunoregulation Effects 0.000 abstract 1
- 235000012054 meals Nutrition 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- -1 oxidation resistance Chemical compound 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 description 9
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- 241000699670 Mus sp. Species 0.000 description 5
- 206010020751 Hypersensitivity Diseases 0.000 description 4
- 241001494479 Pecora Species 0.000 description 4
- 208000026935 allergic disease Diseases 0.000 description 4
- 230000007815 allergy Effects 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 230000003111 delayed effect Effects 0.000 description 4
- 210000002540 macrophage Anatomy 0.000 description 4
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- 241001465754 Metazoa Species 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000000242 pagocytic effect Effects 0.000 description 3
- NHBKXEKEPDILRR-UHFFFAOYSA-N 2,3-bis(butanoylsulfanyl)propyl butanoate Chemical compound CCCC(=O)OCC(SC(=O)CCC)CSC(=O)CCC NHBKXEKEPDILRR-UHFFFAOYSA-N 0.000 description 2
- 206010018910 Haemolysis Diseases 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 125000003748 selenium group Chemical group *[Se]* 0.000 description 2
- 238000002798 spectrophotometry method Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
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- 241000594182 Sarcophaga sigma Species 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 1
- 235000003969 glutathione Nutrition 0.000 description 1
- 229960003180 glutathione Drugs 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 230000008782 phagocytosis Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 201110151696 CN102228469B (zh) | 2011-06-08 | 2011-06-08 | 一种纳米硒颗粒及其制备方法 |
Applications Claiming Priority (1)
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CN 201110151696 CN102228469B (zh) | 2011-06-08 | 2011-06-08 | 一种纳米硒颗粒及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN102228469A true CN102228469A (zh) | 2011-11-02 |
CN102228469B CN102228469B (zh) | 2013-01-16 |
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CN 201110151696 Active CN102228469B (zh) | 2011-06-08 | 2011-06-08 | 一种纳米硒颗粒及其制备方法 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104562067A (zh) * | 2015-01-29 | 2015-04-29 | 桂林理工大学 | 一种纳米红硒光电材料的制备方法 |
CN106219501A (zh) * | 2016-07-26 | 2016-12-14 | 温彩珑 | 一种硒纳米颗粒及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1947792A (zh) * | 2005-10-13 | 2007-04-18 | 暨南大学 | 活性蛋白复合型纳米硒的制备及液相保存技术 |
CN101781643A (zh) * | 2009-01-15 | 2010-07-21 | 河南师范大学 | 蛋白质-硒化银复合纳米材料及制备方法 |
-
2011
- 2011-06-08 CN CN 201110151696 patent/CN102228469B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1947792A (zh) * | 2005-10-13 | 2007-04-18 | 暨南大学 | 活性蛋白复合型纳米硒的制备及液相保存技术 |
CN101781643A (zh) * | 2009-01-15 | 2010-07-21 | 河南师范大学 | 蛋白质-硒化银复合纳米材料及制备方法 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104562067A (zh) * | 2015-01-29 | 2015-04-29 | 桂林理工大学 | 一种纳米红硒光电材料的制备方法 |
CN106219501A (zh) * | 2016-07-26 | 2016-12-14 | 温彩珑 | 一种硒纳米颗粒及其制备方法 |
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Publication number | Publication date |
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CN102228469B (zh) | 2013-01-16 |
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Free format text: FORMER OWNER: SUN ANQUAN YANG ZHIHUA Effective date: 20130823 Owner name: OMEGA BIOTECHNOLOGY (SHANGHAI) CO., LTD. Free format text: FORMER OWNER: ZHU MAOXIANG Effective date: 20130823 |
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Free format text: CORRECT: ADDRESS; FROM: 100039 HAIDIAN, BEIJING TO: 201210 PUDONG NEW AREA, SHANGHAI |
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Effective date of registration: 20130823 Address after: 201210, F3, Mianyang North Road, Zhangjiang Town, Shanghai, Pudong New Area, 185 Patentee after: Omega Biotech Shanghai Co., Ltd. Address before: 100039 No. 27 Taiping Road, Beijing, Haidian District Patentee before: Zhu Maoxiang Patentee before: Sun Anquan Patentee before: Yang Dehua |
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Effective date of registration: 20200327 Address after: 237000 Shouxian County Road, Lu'an economic and Technological Development Zone, Anhui Patentee after: AOGE BIOTECHNOLOGY (LU'AN) Co.,Ltd. Address before: 201210 Pudong New Area, Shanghai Patentee before: OMEGA BIOTECH SHANGHAI Co.,Ltd. |