CN102228421B - Method for preparing novel crocodile-based oily raw material of daily chemical products and application thereof - Google Patents
Method for preparing novel crocodile-based oily raw material of daily chemical products and application thereof Download PDFInfo
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- CN102228421B CN102228421B CN2011101681745A CN201110168174A CN102228421B CN 102228421 B CN102228421 B CN 102228421B CN 2011101681745 A CN2011101681745 A CN 2011101681745A CN 201110168174 A CN201110168174 A CN 201110168174A CN 102228421 B CN102228421 B CN 102228421B
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- oil
- raw material
- crocodile
- scale
- alligator
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Abstract
The invention discloses a method for preparing a novel crocodile-based oily raw material of daily chemical products and application thereof. The method for preparing the oil raw material comprises the following steps of: 1) washing crocodile oil for later use; 2) washing crocodile scales, drying at the temperature of between 60 and 80 DEG C for 2 to 10 hours until the water content of the scales is less than or equal to 1 percent, putting the dried scales into a crusher, and screening with a sieve with the aperture of between 20 and 100 meshes after crushing; and 3) mixing scale powder obtained after crushing and the crocodile oil according to the weight ratio of 1:(2-5), boiling at the temperature of between 90 and 150 DEG C until the amount of an oil body is not increased, and filtering to obtain the oily raw material. Compared with the prior art, the method has the advantages that: the prepared mixture of the crocodile oil and the scales contains proteins, amino acid, organic acid, saturated fatty acid, unsaturated fatty acid, vitamin E, vitamin C, beta-carotene, collagen, polypeptide and the like. The oily raw material has the effects of moisturizing, removing wrinkles, repairing, whitening, resisting senility and the like.
Description
Technical field
The invention belongs to the method for preparing and the application of daily chemical products oiliness new raw material, belong to method for preparing and application especially based on the daily chemical products oiliness new raw material of crocodile.
Background technology
In the daily chemical products, the oiliness raw material can directly influence security of products and stability.Oils and fats relaxes the skin effect as cosmetic material, has the Skin Cell of making softness, increases the cell absorbing power; Suppress the evaporation of epidermis moisture, prevent xerosis cutis, coarse; Avoid machinery and drug-induced stimulation, protective effect is provided; Suppress scytitis, promote the epidermis of exfoliation layer to form.The oils and fats that at present is used for cosmetics has animal oil such as Oleum Cocois, olive oil, Oleum Ricini, almond oil, Oleum Arachidis hypogaeae semen, soybean oil, Oleum Gossypii semen, Petiolus Trachycarpi oil, Oleum sesami, almond oil, wheat germ oil, American Avocado Tree wet goods vegetative grease and mink oil, elgen, cod-liver oil, turtle oil, Adeps Bovis seu Bubali, Adeps Sus domestica, Adeps caprae seu ovis.
The oiliness raw material of existing daily chemical products only have makes Skin Cell soft, prevent xerosis cutis, coarse, avoid machinery and drug-induced stimulation provide protection skin effect, suppress scytitis, promote the basic effects such as epidermis formation of exfoliation layer, need just have given efficacy through adding wetting agent, sunscreen, nourishing additive agent.
Summary of the invention
The 1st technical problem to be solved by this invention provide a kind of itself just have preserve moisture, the method for preparing of the novel daily chemical products oiliness raw material of antioxidation, anti-ultraviolet and trophic function.
The 2nd technical problem to be solved by this invention is the application of above-mentioned raw materials.
The technical scheme of technical solution problem of the present invention is: the method for preparing based on the daily chemical products oiliness new raw material of crocodile may further comprise the steps:
1) alligator oil is cleaned, subsequent use;
2) the crocodile scale is cleaned,,, get and cross 20 orders~100 orders after exsiccant scale is put into the pulverizer pulverizing until scale water content≤1% in 60 ℃~80 ℃ oven dry 2~10 hours;
3) the scale powder that pulverizing is obtained mixes by 1: 2~5 (weight ratios) with above-mentioned alligator oil, and under 90 ℃~150 ℃, boiling to the oil body amount no longer increases, and filters, and gets final product.
Described crocodile is a Chinese alligator.
Described alligator oil is the fat that stores in the Chinese alligator body, and its fatty acid is made up of 16% satisfied fatty acid and 84% unsaturated fatty acid.
The raw material of being produced produce that cleaning skin applies some make up, protects that skin cosmetic, skin nutrition apply some make up, application in the freckle whitening makeup, anti-aging cosmetics, hair washing cosmetics, cosmetic hair care, facial cosmetic cosmetics, eye cosmetics, lip cosmetics, nail salon cosmetics, sun care preparations, anti-perspirant deodorizing cosmetics, leather care products.
The crocodile main body of oil has protein, aminoacid, taurine, unsaturated fatty acid, trace element or the like nutrient substance among the present invention.Its physicochemical property and body fat are close especially; Thereby has a good penetration property; Very easily admit and absorption for human body; Regulate the skin cell metabolic activity with the positive performance of non-general nursing care mode, lifting skin immunologic function, efficiently infiltration, multilamellar are supported comprehensively, preserve moisture lock water, general equilibrium nutrition.
The crocodile scale has the organic matter of 41%-55%, and contains a large amount of collagen protein and tropocollagen matter in these organic matters.Collagen protein is a kind of extracellular protein, and it is to twist into spiral fibrous proteins by 3 peptide chains, and collagen protein is the rich in protein of people's in-vivo content, accounts for more than 30% of whole body gross protein.Collagen protein is rich in aminoacid such as glycine that human body needs, proline, hydroxyproline.Collagen protein is a most important component in the extracellular matrix.Its function is to keep the form and the structure of skin and histoorgan, also is the important source material material of repairing each damaged tissue.In the human body skin composition, form by collagen protein by 70%.Collagen protein can prevent disease, improves body constitution, and is all helpful to beauty treatment and health.
When modulation is combined with the daily chemical products of oiliness raw material of the present invention; As its constituent; Can use or and with employed composition in the common daily chemical products raw material; For example, oiliness raw material, opaque raw material, solvent based raw material, colloid raw material, surfactant, essence, antiseptic, pigment, wetting agent, sunscreen, nourishing additive agent.
Here, as the oiliness raw material, specifically comprise Oleum Cocois, olive oil, Oleum Ricini, almond oil, Oleum Arachidis hypogaeae semen, soybean oil, Oleum Gossypii semen, Petiolus Trachycarpi oil, Oleum sesami, almond oil, wheat germ oil, American Avocado Tree wet goods vegetative grease and; Animal oil such as mink oil, elgen, cod-liver oil, turtle oil, Adeps Bovis seu Bubali, Adeps Sus domestica, Adeps caprae seu ovis; Vegetable wax such as Brazil wax, candelilla wax; Animal waxs such as arctic sperm oil, Cera Flava, spermaceti, lanoline.
As the opaque raw material, specifically comprise Pulvis Talci, Kaolin, zinc white, white titanium pigment, zinc stearate, magnesium stearate, bentonite, calcium carbonate, magnesium carbonate, calcium hydrogen phosphate etc.
As the solvent based raw material, specifically comprise water, ethanol, isopropyl alcohol, n-butyl alcohol, amylalcohol, ethyl acetate etc.
As the colloid raw material, specifically comprise starch, Radix Acaciae senegalis, pectin, sodium alginate, gelatin, methylcellulose, carboxymethyl cellulose, polyvinyl alcohol etc.
As surfactant; Specifically comprise Folium Cocoe locust beam gum, lecithin, carboxy methyl cellulose, sucrose fatty acid ester, diacetyl tartarate list (two) glyceride, Tripolyglycerol monostearates, sodium stearoyl lactate, list (two) tristerin, glyceryl monolaurate, single caprylin etc., the usually composite adding of one or more emulsifying agents during use.
As essence, have that fragrance is pure, temperature tolerance good, stability is high, the persistent characteristics of lasting, odor type has honey peach essence, essence for organi juice, blackberry essence, strawberry essence, flavoring pineapple essence, apple essence, lychee flavor, Fructus Mangifera Indicae essence, Fructus Citri Limoniae essence etc.
As antiseptic, specifically comprise nisin, lysozyme, Nipagin ester, sodium dehydroacetate, sorbic acid etc.
As pigment, specifically comprise alkermes, saffloside, carotene, Rhizoma Curcumae Longae and chlorophyll etc.
As wetting agent, specifically comprise glycerol, propylene glycol, 1,3 butylene glycol, sorbitol, Polyethylene Glycol, lactic acid, hyaluronic acid, hydrolytic collagen etc.
As sunscreen, specifically comprise superfine titanium white, super fine zinc oxide, p-aminobenzoate, salicylate, cinnamate etc.
The present invention compared with prior art, made alligator oil and scale mixture contain protein, aminoacid, organic acid, satisfied fatty acid, unsaturated fatty acid, vitamin E, vitamin C, beta-carotene, collagen protein, polypeptide etc.Have preserve moisture, reduce wrinkle, repair, whiten, the anti-ageing effect of waiting for a long time.Have good penetration property, very easily admit and absorption for human body; Have blood circulation promoting and blood stasis dispelling, active cell regeneration function, quicken metabolism, impel Skin Cell to accelerate succession of the old by the new, thereby effectively keep the vigor of Skin Cell; Have very strong antioxidation, can eliminating chloasma, and protection skin is avoided the injury of UV sunlight; Have restraint of tyrosinase, the blocking-up melanocyte forms, and the black speck that has generated is desalinated gradually, to dispeling freckle etc. better effects is arranged; Can stimulate the human immunocyte to produce antibody, improve immunologic function, engulf pathogenic bacteria virus, reduce the infection and the inflammation of skin.
The specific embodiment
Below in conjunction with embodiment the present invention is done detailed explanation.
Embodiment 1
Get Chinese alligator oil 200g, clean subsequent use;
Get 50g Chinese alligator scale and clean, baking is 9.5 hours in 60 ℃ drying baker, and scale water content≤1% is put into pulverizer pulverizing back with exsiccant scale and crossed 40 orders at this moment;
The scale powder that pulverizing is obtained mixes with above-mentioned Chinese alligator oil puts into pot, and under 100 ℃, boiling to the oil body amount no longer increases, and the liquid of filtration gained is effective ingredient alligator oil of the present invention and scale mixture.
Embodiment 2
Get Chinese alligator oil 200g, clean subsequent use;
Get 60g Chinese alligator scale and clean, baking is 2.5 hours in 80 ℃ drying baker, and scale water content≤1% is put into pulverizer pulverizing back with exsiccant scale and crossed 80 orders at this moment;
The scale powder that pulverizing is obtained mixes with above-mentioned Chinese alligator oil puts into pot, and under 120 ℃, boiling to the oil body amount no longer increases, and the liquid of filtration gained is effective ingredient alligator oil of the present invention and scale mixture.
Embodiment 3
Get Chinese alligator oil 200g, clean subsequent use;
Get 80g Chinese alligator scale and clean, in 60 ℃ drying baker, dry by the fire 9.5h, scale water content≤1% is put into pulverizer pulverizing back with exsiccant scale and is crossed 40 orders at this moment;
The scale powder that pulverizing is obtained mixes with above-mentioned Chinese alligator oil puts into pot, and under 100 ℃, boiling to the oil body amount no longer increases, and the liquid of filtration gained is effective ingredient alligator oil of the present invention and scale mixture.
Embodiment 4
Get Chinese alligator oil 200g, clean subsequent use;
Get 100g Chinese alligator scale and clean, in 60 ℃ drying baker, dry by the fire 9.5h, scale water content≤1% is put into pulverizer pulverizing back with exsiccant scale and is crossed 40 orders at this moment;
The scale powder that pulverizing is obtained mixes with above-mentioned Chinese alligator oil puts into pot, and under 100 ℃, boiling to the oil body amount no longer increases, and the liquid of filtration gained is effective ingredient alligator oil of the present invention and scale mixture.
Embodiment 5
Get Chinese alligator oil 200g, clean subsequent use;
Get 10g Chinese alligator scale and clean, in 60 ℃ drying baker, dry by the fire 9.5h, scale water content≤1% is put into pulverizer pulverizing back with exsiccant scale and is crossed 40 orders at this moment;
The scale powder that pulverizing is obtained mixes with above-mentioned Chinese alligator oil puts into pot, and under 180 ℃, boiling to the oil body amount no longer increases, and the liquid of filtration gained is effective ingredient alligator oil of the present invention and scale mixture.
Embodiment 6
Cleansing cream
Method for preparing:
1, alligator oil and scale mixture, Cera Flava, mono stearate glyceryl ester are dissolved in reaction vessel mixes, and be heated to 60 ℃;
2, glycerol, deionized water are heated to 60 ℃ respectively after, add simultaneously slowly fusing in the reaction vessel in 1, stirring and emulsifying 5min;
3, stir adding Fructus Citri Limoniae essence, ethyl hydroxybenzoate when being cooled to 50 ℃;
4, the continuation stirring is cooled to room temperature and promptly gets product.
Embodiment 7:
Facial milk cleanser cream
Embodiment
1,, and is heated to 70 ℃ with isopropyl fatty acid ester, glycerol, potassium hydroxide, deionized water molten mixing in reaction vessel;
2, alligator oil and scale mixture, lauric acid, Palmic acid, myristic acid, lanoline are heated to 70 ℃, join behind the mix homogeneously in the reaction vessel in 1 and dissolve, stir 10min;
3, stirring cools to 50 ℃ of adding flavoring pineapple essences, methyl hydroxybenzoate, and the continuation stirring is cooled to room temperature and promptly gets product.
Embodiment 8:
Scrubbing cream
Embodiment
1, alligator oil and scale mixture, mono stearate glyceryl ester, Semen Maydis oil, cocamidopropyl betaine, lanonol-3, wool oil are dissolved in reaction vessel mixes, and be heated to 65 ℃;
2, aluminosilicate magnesium, Nux Canarii albi powder, Pericarppium Armeniacae Amarum powder, deionized water are heated to 65 ℃, join behind the mix homogeneously in the reaction vessel in 1 and dissolve, stir 6min;
3, stirring cools to 50 ℃ of adding lactic acid, apple essence, methyl hydroxybenzoate, and the continuation stirring is cooled to room temperature and promptly gets product.
Embodiment 9:
Cream pack
Embodiment
1,, and is heated to 75 ℃ with glycerol, sorbitol, Kaolin, zinc oxide, deionized water mix homogeneously in reaction vessel;
2, alligator oil and scale mixture, emulsified silicone oil, chitin, gelatin are heated to 75 ℃ after, join in the reaction vessel in 1, stir 5min;
3, stirring cools to 50 ℃ of adding triethanolamine, Camellia sinensis essence, methyl hydroxybenzoate, and the continuation stirring is cooled to room temperature and promptly gets product.
Embodiment 10:
Bath foam
Embodiment
1,, and is heated to 75 ℃ with alligator oil and scale mixture, fatty alcohol polyoxyethylene ether sulfate, fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium salt, cocamidopropyl betaine, lauryl alcohol diacetayl amide mix homogeneously in reaction vessel;
2, deionized water is heated to 75 ℃ after, join in the reaction vessel in 1, stir the glycerol that will be heated to 75 ℃ behind the 5min and add;
3, stirring cools to 50 ℃ of adding citric acids, Rhizoma Curcumae Longae, Fructus Citri Limoniae essence, methyl hydroxybenzoate, and the continuation stirring is cooled to room temperature and promptly gets product.
Embodiment 11:
Vanishing cream
Embodiment
1,, and is heated to 95 ℃ with alligator oil and scale mixture, stearic acid butyl alcohol ester, glycerol single-hard ester acid ester, propylene glycol mix homogeneously in reaction vessel;
2, with behind the potassium hydroxide, deionized water and stirring even heating to 95 ℃, join in the reaction vessel in 1, stir 7min;
3, feed circulation warm water 1.5h and stir and be cooled to 50 ℃, add Fructus Citri Limoniae essence, methyl hydroxybenzoate, stop to stir, leave standstill and be cooled to room temperature and promptly get product.
Embodiment 12:
Refined Mercurous chloride
Embodiment
1, titanium dioxide, ferrum oxide (redness of the skin or complexion), ferrum oxide (yellow) are added in the propylene glycol and mix, reconcile into pasty state, grind evenly subsequent use through colloid mill;
2,, and be heated to 95 ℃ with alligator oil and scale mixture, hexadecanol, glycerol single-hard ester acid ester mix homogeneously in reaction vessel;
3, with behind the potassium hydroxide, deionized water and stirring even heating to 95 ℃, join in the reaction vessel in 2, stir 7min;
4, feed circulation warm water and stir and add gained colloid in 1 when being cooled to 75 ℃, continue to feed circulation warm water 1h and stir and be cooled to 50 ℃, add Fructus Citri Limoniae essence, methyl hydroxybenzoate, stop to stir, leave standstill and be cooled to room temperature and promptly get product.
Embodiment 13:
Face cream
Embodiment
1,, and is heated to 95 ℃ with alligator oil and scale mixture, Cera Flava, hard ester acid monoglyceride, ceresine, Borax mix homogeneously in reaction vessel;
2, deionized water is heated to 95 ℃ after, join in the reaction vessel in 1, stir 7min;
3, feeding recirculated water stirs and is cooled to 50 ℃, adds sandalwood fragrance, methyl hydroxybenzoate, and the stirring of continuation feeding recirculated water is cooled to room temperature and promptly gets product.
Embodiment 14:
Sun screen
Embodiment
1,, and is heated to 90 ℃ with alligator oil and scale mixture, isopropyl palmitate, lanolin fatty acid isopropyl ester, mono stearate glyceryl ester, potassium cetyl phosphate mix homogeneously in reaction vessel;
2, glycerol, deionized water are heated to 90 ℃ after, join in the reaction vessel in 1, stir 10min;
3, feed the recirculated water stirring and be cooled to 50 ℃, add benzophenone-4, hyaluronic acid, Fructus Citri Limoniae essence, methyl hydroxybenzoate, continuation feeding recirculated water stirs and is cooled to 40 ℃, stops stirring, is cooled to room temperature and promptly gets product.
Embodiment 15
Skin nutrition applies some make up
Embodiment
1, alligator oil and scale mixture, different hexadecanol hard acid esters, Cortex cocois radicis oil base is sad, hexadeca-octadecyl alcohol, lauryl alcohol-23, dimethyl siloxane, mono stearate glyceryl ester mix homogeneously in reaction vessel, and be heated to 80 ℃;
2, propylene glycol, polyacrylic resin, deionized water are heated to 80 ℃ after, join in the reaction vessel in 1, stir 10min;
3, feed the recirculated water stirring and be cooled to 50 ℃, add vitamin E, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate, methyl parahydroxybenzoate, EDTA-Na
2, triethanolamine, stop to stir, be cooled to room temperature and promptly get product.
Embodiment 16
Skin-lightening cosmetic
Embodiment
1,, and is heated to 75 ℃ with alligator oil and scale mixture, isopropyl palmitate mix homogeneously in reaction vessel;
2, glycerol, ethanol, deionized water are heated to 75 ℃ after, join in the reaction vessel in 1, stir 8min;
3, feed the recirculated water stirring and be cooled to 50 ℃, add L-ascorbic acid-polyoxyethylene addition product, polyoxyethylene nonylphenol ether, methyl parahydroxybenzoate, stop to stir, be cooled to room temperature and promptly get product.
Embodiment 17
Anti-aging cosmetics
Embodiment
1,, and is heated to 85 ℃ with alligator oil and scale mixture, cetyl glucosides, different nonyl isononyl alcohol ester, white oil, poly dimethyl silanol mix homogeneously in reaction vessel;
2, sorbitol, deionized water are heated to 85 ℃ after, join in the reaction vessel in 1, stir 7min;
3, feed the recirculated water stirring and be cooled to 50 ℃, add Herba Menthae essence, methyl parahydroxybenzoate, stop to stir, be cooled to room temperature and promptly get product.
Embodiment 18:
Hair cream
Embodiment
1,, and is heated to 90 ℃ with potassium hydroxide, sodium lauryl sulphate, deionized water mix homogeneously in reaction vessel;
2, alligator oil and scale mixture are dissolved under 90 ℃ in the reaction vessel in the back adding 1, stir 5min;
3, continue to add alkylolamides, the sodium tripolyphosphate that has been warming up to 90 ℃, continue to stir 3min;
4, continue to add the sodium bicarbonate, the methyl parahydroxybenzoate that have been warming up to 90 ℃ and stir into cream;
5, feed the recirculated water stirring and be cooled to 45 ℃, add Camellia sinensis Herba Menthae essence, the discharging that stirs promptly gets product.
Embodiment 19:
Suppurative mastitis
Embodiment
1,, and is heated to 85 ℃ with alligator oil and scale mixture, liquid paraffin, anhydrous lanolin mix homogeneously in reaction vessel;
2, propylene glycol, deionized water are heated to 85 ℃ after, join in the reaction vessel in 1, stir 6min;
3, feed the recirculated water stirring and be cooled to 42 ℃, add triethanolamine, Millefolium natural gum powder, Camellia sinensis Herba Menthae essence, methyl parahydroxybenzoate, stop to stir, be cooled to room temperature and promptly get product.
Embodiment 20
Hair conditioner
Embodiment
1,, and is heated to 70 ℃ with alligator oil and scale mixture, cetyl trimethyl ammonium bromide, octadecanol, glycerol monostearate mix homogeneously in reaction vessel;
2, deionized water is heated to 70 ℃ after, join in the reaction vessel in 1, stir 6min;
3, feed the recirculated water stirring and be cooled to 45 ℃, add Camellia sinensis Herba Menthae essence, lemon yellow pigment, stir, be cooled to room temperature and promptly get product.
Embodiment 21
Hair mousse
Embodiment
1,, and is heated to 80 ℃ with alligator oil and scale mixture mix homogeneously in reaction vessel;
2, glycerol, polyvinylpyrrolidone, polyoxyethylene octadecanol, ethanol, dimethyl ether, deionized water are heated to 80 ℃ after, join in the reaction vessel in 1, stir 6min;
3, feed the recirculated water stirring and be cooled to 45 ℃, add Camellia sinensis Herba Menthae essence, methyl parahydroxybenzoate, stir, be cooled to room temperature and promptly get product.
Embodiment 22
Eye ointment
Embodiment
1,, and is heated to 80 ℃ with alligator oil and scale mixture, anhydrous lanolin, Cera Flava, vaseline mix homogeneously in reaction vessel;
2, glycerol, deionized water are heated to 80 ℃ after, join in the reaction vessel in 1, stir 7min;
3, feed the recirculated water stirring and be cooled to 50 ℃, add triethanolamine, white carbon black, stir, be cooled to room temperature and promptly get product.
Embodiment 23:
Lip pomade
Embodiment
1, color lake, alligator oil and scale mixture, anhydrous lanolin, mono stearate glyceryl ester, isopropyl palmitate, Cera Flava, Brazil wax are mixed under 75 ℃ dissolve;
2, bromic acid is red, Oleum Ricini mixes, and is heated to 75 ℃;
3, with above-mentioned all materials in 75 ℃ of mixing, add Fructus Citri Limoniae essence, grind to form uniform mixed system through colloid mill;
When 4, treating near 65 ℃ of temperature, cast and cooling fast promptly get product.
Embodiment 24
Sunscreen cream
Embodiment
1, with alligator oil and scale mixture, mono stearate glyceryl ester, Cera Flava, ceresine, liquid paraffin, the amino benzoic Acid menthyl ester is mixed in the container and be heated to 75 ℃ dissolves;
2, Borax is mixed in the deionized water, and is heated to 75 ℃;
3, product in 2 is slowly added in 1, and stirring and emulsifying 5min;
4, stir when being cooled to 45 ℃, add Fructus Citri Limoniae essence, be cooled to room temperature and promptly get product.
Embodiment 25
Antiperspirant cream
Embodiment
1, alligator oil and scale mixture, mono stearate glyceryl ester, sodium laurylsulfate are heated to 80 ℃ together;
2, with glycerol, deionized water mixing post-heating to 80 ℃, add in 1 stirring and emulsifying 5min;
Add white titanium pigment when 3, stirring cooling, and the continuation stirring makes mix homogeneously;
4, to be cooled during to 40 ℃, control constant temperature, add aluminum sulfate and continue to be stirred to mastic evenly after, add carbamide and continue and stir until dissolving, add Fructus Citri Limoniae essence again, stir, stop to stir, be cooled to room temperature and promptly get product.
Embodiment 26
Leather care products
Embodiment
1, alligator oil and scale mixture, Cera Flava, mono stearate glyceryl ester are mixed and heated to 85 ℃;
2, glycerol, deionized water are mixed and heated to 85 ℃;
3, under agitation, 2 products therefroms are slowly added in 1, and keep stirring and emulsifying 10min;
4, feed cooling water, stir and be cooled to room temperature, promptly get product.
Embodiment 27:
Study on antioxidation
Get 0.5g embodiment 6 products and be dissolved in the 8ml petroleum ether, be settled to 10ml at last, handle equally and use Adeps Sus domestica to replace the alligator oil of embodiment 1 and the product of scale mixture among the 0.5g embodiment 6.Get 2mlDPPH reagent respectively and add in 6 test tubes, get respectively that 2ml contains the alligator oil of embodiment 1 and the solution of scale mix product adds in 3 above-mentioned test tubes, get the solution that 2ml contains the Adeps Sus domestica product respectively and add in above-mentioned other 3 test tubes.Under spectrophotometer, be blank with the petroleum ether, alligator oil and scale mixture and the Adeps Sus domestica of measuring its absorbance and then calculating embodiment 1 is respectively to the rate of knowing of DPPH reagent.The result shows; The absorbance of DPPH is 0,968, and the absorbance after the alligator oil of embodiment 1 and scale mixture are removed is 0.657, and the absorbance after Adeps Sus domestica is removed is 0.801; The clearance rate of the alligator oil of embodiment 1 and scale mixture is 32.128%, and the clearance rate of Adeps Sus domestica is 17.252%.Through the comparison of clearance rate, the removing effect that can draw alligator oil and the scale mixture of embodiment 1 obviously is better than Adeps Sus domestica, shows that promptly the alligator oil of making example 1 and the whitening anti-wrinkling effect of scale mixture are better than Adeps Sus domestica.
Above-mentioned DPPH reagent is 1, and 1-diphenyl-2-trinitrophenyl-hydrazine is widely used in ground quantitative determination Biosample, the classification material is good and the oxidation resistance of food.This method is according to the DPPH free radical single electron to be arranged, and has the last one to absorb at the 517nm place, and its alcoholic solution is the characteristic of purple.When free radical scavenger existed, owing to its single electron pairing its absorption being faded away, its fading extent became quantitative relationship with the electron amount of its acceptance, thereby available spectrophotometer carries out the rapid quantitative analysis.The concentration of the DPPH reagent that uses in this experiment is 0.2mol/ml.
Above-mentioned spectrophotometric is counted the UV-9200 ultraviolet spectrophotometer.
Embodiment 28: moisture retention research
The glycerol of sample 1:10%; The product of sample 2: embodiment 13;
Use Adeps Sus domestica to replace making the alligator oil of example 1 and the product of scale mixture among sample 3 embodiment 13
Get four and be placed with hygroscopic drying baker, place the saturated solution of calcium chloride, potassium acetate, potassium carbonate, potassium sulfate respectively, the humidity in the control drying baker is respectively 30%, 40%, 60% and 80%.The test specimen rate computing formula of preserving moisture is S (%)=(W
2-W
1) * 100%/W
1Glycerol with 10% is contrast, in each drying baker, places 3 sample 1 samples, 3 sample 2 samples, 3 sample 3 samples respectively.Drying baker is positioned in 20 ℃ the calorstat and measures its rate of preserving moisture behind the 24h, the result gets its meansigma methods, and is as shown in the table.
Sample 1 sample | Sample 2 samples | Sample 3 samples | |
30% humidity | -22.25 | -5.25 | -6.75 |
40% humidity | -19.25 | -4.75 | -6.25 |
60% humidity | -17.00 | -3.25 | -4.75 |
80% humidity | -12.00 | -2.00 | -2.75 |
Can find out from last table; Sample 2 and 3 product moisture retention obviously are superior to the moisture retention of sample 1 product; And the moisture retention of sample 2 samples is superior to sample 3 samples to a certain extent; Can draw the alligator oil of manufacturing example 1 and the moisture retention of scale mixture and not only be superior to 10% glycerol, also be superior to the moisture retention of Adeps Sus domestica.
Embodiment 29: the mensuration of collagen content
Sample: embodiment 1 product, embodiment 3 products, embodiment 5 products
Test method
Getting 4g sample adding 30ml concentration is in the sulfuric acid solution of 3mol/L, covers with surface plate, is positioned over 105 ℃ the interior constant temperature 16h of drying baker.While hot hydrolyzate is filtered in the 250mL volumetric flask with circular filter paper, uses 10mL concentration to divide three washing flasks and filter paper as the sulfuric acid solution of 3mol/L, be incorporated into above-mentioned volumetric flask, the water standardize solution shakes up.Pipette this hydrolyzed solution of 10mL to the 250mL volumetric flask with pipet, standardize solution shakes up.Pipette the above-mentioned solution of 4.00mL in color comparison tube, add 2.00mL toluene-sodium-sulfonchloramide reagent, mix the back in room temperature held 20min.Add the 2.00mL developer in color comparison tube, fully mix, color comparison tube is sealed, put into 60 ℃ of water-baths rapidly and heat 20min with plastic sheeting.Take out color comparison tube, flowing water cooling raio colour tube is 3min at least, room temperature held 30min.Water is cooked reference, surveys light absorption value in the 558nm place.Parallel two groups.Replace dilute solution to do control experiment with distilled water.
Described toluene-sodium-sulfonchloramide solution, faces and uses preceding preparation with the dissolving of 100mL buffer solution for taking by weighing 1.41g three water N-chloro-Chloramine salt (toluene-sodium-sulfonchloramide).
Described developer with 35mL perchloric acid solution (mass fraction 60%) dissolving, slowly adds the 65mL isopropyl alcohol for taking by weighing the 10.0g paradime thylaminobenzaldehyde.Face and use preceding preparation.
The result is following: the light absorption value of embodiment 1,3,5 products is respectively 0.956,0.960,0.794.
We can find out by The above results; Scale powder that pulverizing obtains and Chinese alligator oil help by 1: 4~5 mixed that collagen is proteic in the scale separates out; Ratio is crossed the low collagen content product efficacy that influences on the low side in the routine gained mixture of then making, and ratio is too high then to be the waste to raw material.Embodiment 1 is the different of temperature with 5 main difference; The temperature that embodiment 1 extracts alligator oil and scale mixture has only 100 ℃; The extraction temperature of embodiment 5 then reaches 180 ℃. and difference shows that the routine 5 gained mixture impurity of manufacturing obviously increase, clarity obviously reduces; Through verifying example 3 mensuration for collagen protein, the collagen content of embodiment 5 gained mixture is starkly lower than embodiment 1 gained mixture.
Embodiment 30: acute toxicity
The alligator oil of embodiment 1 and scale mixture with the amount of every 2000mg/kg, to each 10 oral administration of white mice male and female, when observing, are confirmed not have dead example and different shape example.
Embodiment 31: skin irritation
Following compositions is mixed into respectively in the hydrophilic vaseline,, it is used as sample so that its concentration is 5%.
1, hydrophilic vaseline (contrast); 2, the alligator oil of embodiment 1 and scale mixture 3, arbutin (duplicate A) 4, vitamin C (duplicate B)
Test method
Each 5 of the adult men and women at age 20~50 are used the inboard of each upper arm of ethanol wiping respectively as the testee,, stick each the sample 0.2g on the aluminium sheet of coating the fin cell respectively at this position to remove sebum.After 24 hours, remove the fin cell, judge stimulation degree skin according to following method and benchmark.
Judge
After 1 hour after removing patch, after 24 hours, after 48 hours, according to once " adopting the skin irritation determinating reference of Draizetest method ", the erythema at obedient position and the situation of edema are glued in visual judgement, obtain 10 testees' meansigma methods.
Table 1:
Scoring | Erythema (state of skin) | Edema (state of skin) |
0 | No erythema | No edema |
1 | Extremely slight erythema | Extremely slight edema |
2 | Tangible erythema | Tangible edema |
3 | Moderate to intensive erythema | Moderate edema (protuberance that 1mm is above) |
4 | Wine-colored strong erythema forms slight crust | Strong edema (protuberance be extended to around) |
The result
In this experiment; The whitening agent, the whitening agent of b, wetting agent, the antioxidant that are used for the duplicate a of comparison; Therefore its safety is general in the material of making up than higher, can find out from last table result; Alligator oil of the present invention and scale mixture also lack than these additives in the past the zest of skin, and safety is extremely good.
Embodiment 32
The testing staff tests (one)
For the product of the embodiment 6,9,10,12 that obtains with alligator oil of the present invention and scale mixture, estimate use feeling and safety with the actual use test of using the testing staff.
Test method
With the age of selecting at random is that 15~50 years old each 10 of men and women for the product of embodiment 6,9,10,12, used 5 days the use feeling when being coated with according to following projects evaluation, zest etc. continuously as estimating the group member.
Evaluation is the state for use feeling and skin, estimates (A: good, B: general, C: poor) according to 3 grades, estimates (A: non-stimulated, B: sense of discomfort is arranged, C: stimulation is arranged) for zest according to 3 grades in addition.
1) gets on hand sensation; Extensibility when 2) being coated with; Lubricated sense when 3) being coated with; 4) penetration property; 5) sensation after the coating; 6) the skin state after the use; Zest when 7) being coated with; 8) zest after the use
Result: table 3
As above shown in the table, the product of the embodiment 6,9,10,11 that obtains with alligator oil of the present invention and scale mixture obtains higher evaluation aspect use feeling, and to skin also not stimulation fully.
Embodiment 33:
The product of sample 1: embodiment 18,
Use the product of displaced alligator oil of Adeps Sus domestica and scale mixture among sample 2: the embodiment 18
Test method
Each 10 of men and women that with the age of selecting at random are 15~50 years old are as estimating the group member, with sample 1. and be used for hair in 2. continuous several days, behind the two weeks, for the integral body sight and the gloss that are prone to cardability, hair, estimate according to evaluation criterion once.
A: significantly improve; B: improve; C: constant; D: variation slightly; E: remarkable variation
Table 4 as a result:
As above shown in the table, hair cream and the hair conditioner of the embodiment 13,15 that obtains with alligator oil of the present invention and scale mixture have the performances such as protective effect of certain moisture retention, lubricity, hair quality, the easy cardability of hair are improved, simultaneously hair quality health.
The properties of product of embodiment 1-4 are following:
Product detects
Claims (2)
1. based on the method for preparing of the daily chemical products oiliness new raw material of crocodile, may further comprise the steps:
1) alligator oil is cleaned, subsequent use;
2) the crocodile scale is cleaned,,, get and cross 20 orders~100 orders after exsiccant scale is put into the pulverizer pulverizing until scale water content≤1% in 60 ℃~80 ℃ oven dry 2~10 hours;
3) the scale powder that pulverizing is obtained mixes by 1: 2~5 (weight ratios) with above-mentioned alligator oil, and under 90 ℃~150 ℃, boiling to the oil body amount no longer increases, and filters, and gets final product;
Described crocodile is a Chinese alligator;
Described alligator oil is the fat that stores in the Chinese alligator body, and its fatty acid is made up of 16% satisfied fatty acid and 84% unsaturated fatty acid.
The raw material produced of claim 1 produce that cleaning skin applies some make up, protects that skin cosmetic, skin nutrition apply some make up, application in the freckle whitening makeup, anti-aging cosmetics, hair washing cosmetics, cosmetic hair care, facial cosmetic cosmetics, eye cosmetics, lip cosmetics, nail salon cosmetics, sun care preparations, anti-perspirant deodorizing cosmetics, leather care products.
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CN103238871A (en) * | 2013-05-29 | 2013-08-14 | 胡素芳 | Fish scale powder processing method |
CN104312724A (en) * | 2014-09-24 | 2015-01-28 | 上海制皂有限公司 | Sandalwood-containing aromatic piece |
KR101512606B1 (en) * | 2014-12-11 | 2015-04-15 | (주)이지코스 | Cosmetic composition for improving wrinkle and atopic dermatitis and moisturizing |
CN105520900A (en) * | 2015-12-25 | 2016-04-27 | 北京百生康生物科技有限公司 | Anti-ageing and rejuvenating alligator oil face cream |
CN105534782A (en) * | 2015-12-25 | 2016-05-04 | 北京百生康生物科技有限公司 | Alligator oil acne removing and spot thinning essence cream |
CN107536733A (en) * | 2016-06-27 | 2018-01-05 | 李启初 | A kind of crocodile maintenance oil and preparation method thereof |
CN105997823A (en) * | 2016-07-14 | 2016-10-12 | 湖南湘湖水产有限公司 | Turtle oil and egg white beauty mask |
CN107951750B (en) * | 2017-12-14 | 2021-04-06 | 广东省保化检测中心有限公司 | Sunscreen composition, sunscreen product and preparation method of sunscreen product |
CN108066274B (en) * | 2018-01-25 | 2021-03-30 | 深圳市大鳄生物科技股份有限公司 | Hair blackening compound and preparation method and application thereof |
CN108441315A (en) * | 2018-04-28 | 2018-08-24 | 安徽师范大学 | Chinese alligator deodorant Grease preparation method |
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