CN102225163B - Traditional Chinese medicine composition for treating heatstroke and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating heatstroke and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating heatstroke, which has a formula comprising the following components: 3-5 parts of rhinoceros horns or 9-15 parts of buffalo horns, 8-12 parts of antelope horns, 10-20 parts of rehmanniae radix, 20-30 parts of radix scrophulariae, 20-30 parts of liriope 20-30 parts of honeysuckle, 25-35 parts of forsythia suspense, 25-35 parts of salvia, 8-12 parts of coptis, 8-12 parts of sinocalamus affinis, 8-12 parts of clerodendroa cyrtophyllum, 8-12 parts of purple snow elixir on a mass basis. The composition of the invention can treat heatstroke fundamentally through clearing heat and relieving exterior syndromes, clearing yingqi and removing toxic substances, penetrating heat and nourishing yin, and has short treating cycle, low cost, less toxic and side effect, and ideal treatment effect. The clinical cure rate is up to 91.5%, and the total effective rate is up to 97.9%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition of treating heatstroke, belong to pure Chinese herbal medicine, also relate to its preparation method.
Background technology
Heatstroke is meant that performance is the disease of characteristic too much with thermotaxic centre dysfunction, sweat gland MSOF and Water-Electrolyte forfeiture under summer-heat weather, high humidity and calm environmental condition, and the traditional Chinese medical science is called summer-heat.Medication has bigger toxic and side effects in treatment at present, and cost is high, can not be satisfactory aspect therapeutic effect.
Summary of the invention
Technical problem to be solved by this invention is, a kind of Chinese medicine composition of treating heatstroke is provided, induce sweat through heat radiation, and the clearing heat in YING system detoxifcation, diathermanous yin nourishing, fundamentally treatment heatstroke is to overcome the defective of existing such disease medicine of treatment.
It is following that the present invention solves the problems of the technologies described above the technical scheme that is adopted:
A kind of Chinese medicine composition of treating heatstroke is characterized in that its prescription is: Cornu rhinocerotis 3-5 part or Cornu Bubali 9-15 part, Cornu Saigae Tataricae 8-12 part, Radix Rehmanniae 10-20 part; Radix Scrophulariae 20-30 part, Radix Ophiopogonis 20-30 part, Flos Lonicerae 20-30 part, Fructus Forsythiae 25-35 part; Radix Salviae Miltiorrhizae 25-35 part, Rhizoma Coptidis 8-12 part, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure 8-12 part; Folium Isatidis 8-12 part, ZIXUEDAN 8-12 part, described part refers to mass parts.
Preferred prescription is: 12 parts of 4 parts of Cornu rhinocerotiss or Cornu Bubalis, 10 parts of Cornu Saigae Tataricae, 15 parts in the Radix Rehmanniae, 25 parts of Radix Scrophulariaes, 25 parts of Radix Ophiopogonis, 25 parts of Flos Lonicerae, 30 parts of Fructus Forsythiaes, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Coptidis, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 10 parts of Folium Isatidiss, 10 parts of ZIXUEDAN.
A kind of Chinese medicine composition of treating heatstroke is characterized in that its preparation method is:
(1) Cornu rhinocerotis, the Cornu Saigae Tataricae with said ratio is twisted into powder, with the ZIXUEDAN mix homogeneously of said ratio as the A component;
(2) with the Radix Rehmanniae, Radix Scrophulariae, Radix Ophiopogonis, Flos Lonicerae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, the Folium Isatidis mix homogeneously of said ratio, be ground into 80 order granules;
(3) (2) step mixture is put into Kanakin bag steaming and decocting 30 minutes, will steam liquid and be cooled to room temperature, connected bag steaming and decocting again 20 minutes, cloth bag is immersed in steams in the liquid while hot, stir; Cool to room temperature;
(4) steam liquid with filtered through gauze, waste must be filtrated.
(5) the filtrating heating of (4) gained is concentrated, ceases fire during fast evaporate to dryness and stir, be cooled to room temperature, decorating film B component;
(6) with A and B component mixed grinding, pill.
The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are following:
Cornu rhinocerotis: nature and flavor acid is salty, and is cold.Be antipyretic, heat removing and blood cooling medicine.Function heat clearing away, removing heat from blood, arresting convulsion, detoxifcation.
Cornu Saigae Tataricae: meridian distribution of property and flavor: cold; Salty; Return liver, heart channel.Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, the blood detoxifcation of loosing.Be used for the frightened carbuncle of hyperpyrexia, the coma convulsion is fainted, and eclamposia is twitched, and epilepsy is gone mad, and it is dizzy to have a headache, the conjunctival congestion cataracta, and warm poison is gone mad, carbuncle sore tumefacting virus.
The Radix Rehmanniae: meridian distribution of property and flavor: cold; Sweet, bitter; GUIXIN, liver, kidney channel.Function cures mainly: be used for calentura crimson tongue excessive thirst, and interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.
Radix Scrophulariae: meridian distribution of property and flavor: be slightly cold; Sweet, bitter, salty; Return lung, stomach, kidney channel.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.Be used for consumption of YIN caused by febrile disease, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Radix Ophiopogonis: meridian distribution of property and flavor: be slightly cold; Sweet, little hardship; GUIXIN, lung, stomach warp.Function cures mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough.The chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, the dryness of the intestine constipation; Pharyngeal diphtheria.
Flos Lonicerae: meridian distribution of property and flavor: cold; Sweet; Return lung, the heart, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, wind-heat dissipating.Be used for carbuncle and treat skin ulcer, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating.
Fructus Forsythiae: meridian distribution of property and flavor: be slightly cold; Bitter; Return lung, the heart, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Be used for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, the hyperpyrexia excessive thirst, coma is sent out speckle, the pyretic stranguria urine retention.
Radix Salviae Miltiorrhizae: meridian distribution of property and flavor: be slightly cold; Bitter; GUIXIN, Liver Channel.Function cures mainly: stasis-dispelling and pain-killing, and promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, the amenorrhea dysmenorrhea, the miasma abdominal mass is gathered, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Rhizoma Coptidis: meridian distribution of property and flavor: cold; Bitter; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, yellow cellulitis, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache is quenched one's thirst, and carbuncle is treated skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.
Unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure: meridian distribution of property and flavor: cold; Sweet, hot, light; GUIXIN, stomach, small intestine meridian.Function cures mainly: clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid.Be used for the calentura excessive thirst, aphtha dark coloured urine, epidemic febrile disease pathogens intruding into the pericardium, the disease of unconsciousness and delirium.
Folium Isatidis: meridian distribution of property and flavor: cold; Bitter; GUIXIN, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Be used for pathogenic warmth and join the army, unconsciousness due to high fever is sent out the speckle dermexanthesis, yellow cellulitis, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.
ZIXUEDAN: heat-clearing and toxic substances removing, spasmolytic relieves dizziness, high fever, infantile convulsions, epilepsy, etc., the arresting convulsion of having one's ideas straightened out.Cure mainly epidemic febrile disease, the pathogenic heat pericardium that caves in, disease sees that hyperpyrexia is irritated, and unconsciousness and delirium, convulsion convulsion are fainted, thirsty parched lips, and dark coloured urine just closes, and excessive heat of infant is fainted from fear.
The Fang Xieyu good effect: we are effective prescriptions of treatment heatstroke, and the traditional Chinese medical science is thought: divide when pathogenic warmth changes battalion over to by edema caused by disorder of QI, thermal burn battalion's the moon and the heresy of edema caused by disorder of QI are not separated and are increased the weight of, so fever aggravated at night; Blood is compeled because of heat, and channels is injured, and heat is disturbed the mind, the fever of the body excessive thirst, person's stupor very, the time delirium arranged, crimson tongue and dried be cloudy the resembling of thermal burn battalion, so on method of treatment, should be main, hold concurrently, and reach the purpose of clearing away heat from both QI and YING systems with the heat of clear disappointing branch with the clearing heat in YING system detoxifcation.Therefore, the present invention is with the pyretic toxicity of Cornu rhinocerotis removing summer-heat battalion branch, because of the cloudy liquid of thermal burn, so be aided with Radix Scrophulariae, the Radix Rehmanniae, Radix Ophiopogonis with clearing away heat and nourishing YIN; Because the heat of edema caused by disorder of QI is not to the greatest extent, Gu Zuo rushing down the edema caused by disorder of QI pathogenic heat clearly, double separates warm poison with Rhizoma Coptidis, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, Fructus Forsythiae, Flos Lonicerae; And can be diathermanous in outside; Make pathogenic heat change edema caused by disorder of QI over to and separate, make with Radix Salviae Miltiorrhizae and assist with clearing away heat and cooling blood, and can promoting blood circulation to remove blood stasis; In case blood and accumulation of heat, and can draw all medicines again and go into the heart and heat clearing away.ZIXUEDAN also can heat-clearing and toxic substances removing, and spasmolytic relieves dizziness, high fever, infantile convulsions, epilepsy, etc., the arresting convulsion of having one's ideas straightened out.All medicines share, and play the clearing heat in YING system detoxifcation altogether, the effect of diathermanous yin nourishing.So medicine of the present invention can fundamentally be treated heatstroke, and treatment cycle is short, and cost is low, and toxic and side effects is little, and therapeutic effect is desirable.
Obtained tangible clinical effectiveness through clinical practice, cure rate reaches 91.5%, and total effective rate reaches 97.9%, no obvious toxic-side effects.
The specific embodiment
Further specify the present invention below in conjunction with concrete preparation instance.
Prescription instance one:
The set of dispense ratio is: 3 parts of Cornu rhinocerotiss, 8 parts of Cornu Saigae Tataricae, 10 parts in the Radix Rehmanniae, 20 parts of Radix Scrophulariaes, 20 parts of Radix Ophiopogonis, 20 parts of Flos Lonicerae, 25 parts of Fructus Forsythiaes, 25 parts of Radix Salviae Miltiorrhizaes, 8 parts of Rhizoma Coptidis, 8 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 8 parts of Folium Isatidiss, 8 parts of ZIXUEDAN.
Method for preparing: get 3 parts of Cornu rhinocerotiss, 8 parts of Cornu Saigae Tataricae are twisted into powder, with 8 parts of ZIXUEDAN mix homogeneously as the A component.With 10 parts of Radix Rehmanniae, 20 portions of Radix Scrophulariaes, 20 parts of Radix Ophiopogonis, 20 parts of Flos Lonicerae, 25 parts of Fructus Forsythiaes, 25 parts of Radix Salviae Miltiorrhizaes, 8 portions of Rhizoma Coptidis, 8 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure and 8 parts of Folium Isatidis mix homogeneously, be ground into 80 order granules.Hybrid particles is put into Kanakin bag steaming and decocting 30 minutes, will steam liquid and be cooled to room temperature, connected bag steaming and decocting again 20 minutes, cloth bag is immersed in steams in the liquid while hot, stir.Cool to room temperature.Steam liquid with filtered through gauze, waste must be filtrated.The heating of will filtrating concentrates, and ceases fire during fast evaporate to dryness and stirs, and is cooled to room temperature, decorating film B component.With A and B component mixed grinding, pill.
Instructions about how to take medicine and usage: oral every clothes 1.5-2.5 gram, every day 2 times.
Prescription instance two:
The set of dispense ratio is: 4 parts of Cornu rhinocerotiss, 10 parts of Cornu Saigae Tataricae, 15 parts in the Radix Rehmanniae, 25 parts of Radix Scrophulariaes, 25 parts of Radix Ophiopogonis, 25 parts of Flos Lonicerae, 30 parts of Fructus Forsythiaes, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Coptidis, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 10 parts of Folium Isatidiss, 10 parts of ZIXUEDAN.
Method for preparing: get 4 parts of Cornu rhinocerotiss, 10 parts of Cornu Saigae Tataricae are twisted into powder, with 10 parts of ZIXUEDAN mix homogeneously as the A component.With 15 parts of Radix Rehmanniae, 25 portions of Radix Scrophulariaes, 25 parts of Radix Ophiopogonis, 25 parts of Flos Lonicerae, 30 parts of Fructus Forsythiaes, 30 parts of Radix Salviae Miltiorrhizaes, 10 portions of Rhizoma Coptidis, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure and 10 parts of Folium Isatidis mix homogeneously, be ground into 80 order granules.Hybrid particles is put into Kanakin bag steaming and decocting 30 minutes, will steam liquid and be cooled to room temperature, connected bag steaming and decocting again 20 minutes, cloth bag is immersed in steams in the liquid while hot, stir.Cool to room temperature.Steam liquid with filtered through gauze, waste must be filtrated.The heating of will filtrating concentrates, and ceases fire during fast evaporate to dryness and stirs, and is cooled to room temperature, decorating film B component.With A and B component mixed grinding, pill.
Instructions about how to take medicine and usage are with embodiment one.
Prescription instance three:
The set of dispense ratio is: 15 parts of Cornu Bubalis, 12 parts of Cornu Saigae Tataricae, 20 parts in the Radix Rehmanniae, 30 parts of Radix Scrophulariaes, 30 parts of Radix Ophiopogonis, 30 parts of Flos Lonicerae, 35 parts of Fructus Forsythiaes, 35 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Coptidis, 12 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 12 parts of Folium Isatidiss, 12 parts of ZIXUEDAN.
Method for preparing: get 5 parts of Cornu rhinocerotiss, 12 parts of Cornu Saigae Tataricae are twisted into powder, with 12 parts of ZIXUEDAN mix homogeneously as the A component.With 20-part Radix Rehmanniae, 30 portions of Radix Scrophulariaes, 30 parts of Radix Ophiopogonis, 30 parts of Flos Lonicerae, 35 parts of Fructus Forsythiaes, 35 parts of Radix Salviae Miltiorrhizaes, 12 portions of Rhizoma Coptidis, 12 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure and 12 parts of Folium Isatidis mix homogeneously, be ground into 80 order granules.Hybrid particles is put into Kanakin bag steaming and decocting 30 minutes, will steam liquid and be cooled to room temperature, connected bag steaming and decocting again 20 minutes, cloth bag is immersed in steams in the liquid while hot, stir.Cool to room temperature.Steam liquid with filtered through gauze, waste must be filtrated.The heating of will filtrating concentrates, and ceases fire during fast evaporate to dryness and stirs, and is cooled to room temperature, decorating film B component.With A and B component mixed grinding, pill.
Instructions about how to take medicine and usage are with embodiment one.
It below is clinical report
From year July in July, 2008 to 2010, the inventor uses the present invention's instance two treatment heatstroke patients 75 examples of writing out a prescription in Yantai Traditional Chinese Medical-science (TCM) Hospital, and treats 30 examples and carry out controlled observation with using oral HUOXIANG ZHENGQI SHUI the same period, receives better effects, and existing report as follows.
1, clinical data
Physical data is observed case totally 105 examples, is divided into 2 groups at random.75 examples are organized in treatment, male 30 examples, women 45 examples; Year at age (39.5 ± 15.27); The course of disease (3 ± 1) sky; Matched group 30 examples, male 20 examples, women 10 examples; Year at age (39.5 ± 15.27); The course of disease (3 ± 1) sky.2 groups of physical data are through statistical procedures, and there are no significant that meaning (P＞0.05) has comparability for difference.
2, Therapeutic Method
2.1 matched group adopts oral HUOXIANG ZHENGQI SHUI every day 2 times.1 week of the course of treatment.
2.2 the treatment group adopts oral each 2 grams of oral medicine of the present invention, every day 2 times.1 week of the course of treatment.
2.3 observation item is clinical efficacy 1.; 2. the heavy or headache of head before and after the treatment, thirsty, cases of dehydration, body heat.
2.4 statistical method adopts the SPSS statistical software to analyze.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, lab testing improve or are normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.
3.2 therapeutic outcome
2 groups of clinical efficacies are relatively seen table 1.Total effective rate treatment group is 87.9%, and matched group is 76.6%, 2 group and compares that difference has significance meaning (P＜0.05).
Table 1 liang group clinical efficacy relatively
With preceding relatively ※ P＜0.01 of treatment; With comparison after the treatment of control group, Δ P＜0.01
This shows that medicine of the present invention is superior to other medicines for treatment heatstroke effect, cures the effective percentage height.
Claims (1)
1. a Chinese medicine of treating heatstroke is characterized in that raw material is: 12 parts of 4 parts of Cornu rhinocerotiss or Cornu Bubalis, 10 parts of Cornu Saigae Tataricae, 15 parts in the Radix Rehmanniae, 25 parts of Radix Scrophulariaes; 25 parts of Radix Ophiopogonis, 25 parts of Flos Lonicerae, 30 parts of Fructus Forsythiaes, 30 parts of Radix Salviae Miltiorrhizaes; 10 parts of Rhizoma Coptidis, 10 parts of unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, 10 parts of Folium Isatidiss, 10 parts of ZIXUEDAN;
Method for preparing is:
(1) Cornu rhinocerotis, the Cornu Saigae Tataricae with said ratio is twisted into powder, with the ZIXUEDAN mix homogeneously of said ratio as the A component;
(2) with the Radix Rehmanniae, Radix Scrophulariae, Radix Ophiopogonis, Flos Lonicerae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure, the Folium Isatidis mix homogeneously of said ratio, be ground into 80 order granules;
(3) (2) step mixture is put into Kanakin bag steaming and decocting 30 minutes, will steam liquid and be cooled to room temperature, connected bag steaming and decocting again 20 minutes, cloth bag is immersed in steams in the liquid while hot, stir; Cool to room temperature;
(4) steam liquid with filtered through gauze, waste must be filtrated;
(5) the filtrating heating of (4) gained is concentrated, ceases fire during fast evaporate to dryness and stir, be cooled to room temperature, decorating film B component;
(6) with A and B component mixed grinding, pill.
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| CN104491341A (en) * | 2014-11-29 | 2015-04-08 | 李跃 | Traditional Chinese medicine formula for preventing and treating sunstroke |
| CN104524296A (en) * | 2014-12-31 | 2015-04-22 | 陈月玲 | Traditional Chinese medicine composition for treating summerheat-heat stirring wind syndrome pattern summerheat convulsive disease |
| CN105748995A (en) * | 2016-03-30 | 2016-07-13 | 滕钜海 | Traditional Chinese medicine composition for treating heatstroke and preparation method thereof |
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| 张家锡主编.中暑.《中医诊断学》.四川科学技术出版社,2007,(第1版),第236页. * |
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