CN102216323B - 用于调节慢性炎症反应和治疗自身免疫性疾病的源自il-4的肽 - Google Patents

用于调节慢性炎症反应和治疗自身免疫性疾病的源自il-4的肽 Download PDF

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CN102216323B
CN102216323B CN200980145907.4A CN200980145907A CN102216323B CN 102216323 B CN102216323 B CN 102216323B CN 200980145907 A CN200980145907 A CN 200980145907A CN 102216323 B CN102216323 B CN 102216323B
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disease
peptide
amino acid
tnf
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CN102216323A (zh
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伊丽莎白·博克
瓦拉迪米·别列津
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Koebenhavns University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
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CN200980145907.4A 2008-11-17 2009-11-17 用于调节慢性炎症反应和治疗自身免疫性疾病的源自il-4的肽 Expired - Fee Related CN102216323B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200801601 2008-11-17
DKPA200801601 2008-11-17
PCT/DK2009/050304 WO2010054667A1 (en) 2008-11-17 2009-11-17 Il-4-derived peptides for modulation of the chronic inflammatory response and treatment of autoimmune diseases

Publications (2)

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CN102216323A CN102216323A (zh) 2011-10-12
CN102216323B true CN102216323B (zh) 2016-08-03

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CN200980145907.4A Expired - Fee Related CN102216323B (zh) 2008-11-17 2009-11-17 用于调节慢性炎症反应和治疗自身免疫性疾病的源自il-4的肽

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US (1) US8546321B2 (https=)
EP (1) EP2365983B1 (https=)
JP (1) JP5750373B2 (https=)
CN (1) CN102216323B (https=)
AU (1) AU2009316076B2 (https=)
BR (1) BRPI0921717A2 (https=)
CA (1) CA2743394C (https=)
ES (1) ES2620437T3 (https=)
IL (1) IL212962A0 (https=)
NZ (1) NZ592943A (https=)
RU (1) RU2542375C2 (https=)
WO (1) WO2010054667A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20200470T1 (hr) 2011-01-18 2020-10-02 Bioniz, Llc Pripravci za modulaciju aktivnosti gama-c-citokina
US9959384B2 (en) 2013-12-10 2018-05-01 Bioniz, Llc Methods of developing selective peptide antagonists
AU2016239858B2 (en) 2015-04-02 2021-07-01 Intervet International B.V. Antibodies to canine interleukin-4 receptor alpha
CN119684428A (zh) 2015-10-09 2025-03-25 比奥尼斯治疗公司 调节γC-细胞因子活性
WO2018187499A1 (en) * 2017-04-07 2018-10-11 Bioniz, Llc Stable modulators of gamma-c-cytokine activity
KR102095284B1 (ko) * 2017-05-11 2020-04-01 (주)케어젠 메토트렉세이트와 펩타이드의 결합체
ES2971898T3 (es) 2018-02-27 2024-06-10 Univ Der Johannes Gutenberg Univ Mainz Nuevos compuestos peptídicos obtenidos a partir de IL-4-/IL-13 para el tratamiento o la prevención de enfermeda-des neurodegenerativas o neuroinflamatorias
CN110746507B (zh) * 2018-12-25 2020-06-26 江苏荃信生物医药有限公司 抗人白介素4受体α单克隆抗体及其应用
EP3976182A4 (en) 2019-05-03 2023-01-18 Bioniz, LLC MODULATION OF THE EFFECTS OF GAMMA CYTOKINE SIGNALING FOR THE TREATMENT OF ALOPECIA AND ALOPECIA-ASSOCIATED DISORDERS
CA3242457A1 (en) * 2022-01-05 2023-07-13 Serodus Aps Il-4 derived peptides for use in the treatment of obesity
CN118475362A (zh) 2022-04-29 2024-08-09 塞罗德斯有限公司 用于治疗糖尿病肾病的il-4衍生肽片段

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009059A1 (en) * 1989-12-20 1991-06-27 Schering Corporation Antibody antagonists of human interleukin-4
US6337072B1 (en) * 1998-04-03 2002-01-08 Hyseq, Inc. Interleukin-1 receptor antagonist and recombinant production thereof
CN1649898A (zh) * 2002-04-10 2005-08-03 维克斯咨询公司 新型肽及其的治疗中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05503088A (ja) * 1989-11-21 1993-05-27 ザ ユニバーシティー オブ メルボルン 抗炎症用の組成物及び方法
HU229520B1 (en) * 1999-02-12 2014-01-28 Scripps Research Inst Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
GB9912350D0 (en) * 1999-05-26 1999-07-28 European Molecular Biology Lab Embl Modified cytokine
US20030056244A1 (en) * 2000-05-02 2003-03-20 Ning Huang Feed additive compositions and methods
WO2004096849A2 (en) * 2003-04-25 2004-11-11 University Of Manitoba Peptide-based cytokine/chemokine vaccines against allergy
US20070207947A1 (en) * 2003-10-16 2007-09-06 Aplagen Gmbh Stabilized Peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009059A1 (en) * 1989-12-20 1991-06-27 Schering Corporation Antibody antagonists of human interleukin-4
US6337072B1 (en) * 1998-04-03 2002-01-08 Hyseq, Inc. Interleukin-1 receptor antagonist and recombinant production thereof
CN1649898A (zh) * 2002-04-10 2005-08-03 维克斯咨询公司 新型肽及其的治疗中的应用

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Publication number Publication date
AU2009316076B2 (en) 2015-11-19
ES2620437T3 (es) 2017-06-28
BRPI0921717A2 (pt) 2018-10-09
CA2743394A1 (en) 2010-05-20
CA2743394C (en) 2018-01-02
WO2010054667A1 (en) 2010-05-20
RU2011121971A (ru) 2012-12-27
AU2009316076A1 (en) 2010-05-20
CN102216323A (zh) 2011-10-12
US8546321B2 (en) 2013-10-01
US20110300148A1 (en) 2011-12-08
JP2012508698A (ja) 2012-04-12
JP5750373B2 (ja) 2015-07-22
NZ592943A (en) 2012-09-28
EP2365983B1 (en) 2016-12-28
EP2365983A1 (en) 2011-09-21
RU2542375C2 (ru) 2015-02-20
IL212962A0 (en) 2011-07-31

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