CN102204961A - Digua fig stem extract and new application thereof - Google Patents
Digua fig stem extract and new application thereof Download PDFInfo
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- CN102204961A CN102204961A CN2011100816514A CN201110081651A CN102204961A CN 102204961 A CN102204961 A CN 102204961A CN 2011100816514 A CN2011100816514 A CN 2011100816514A CN 201110081651 A CN201110081651 A CN 201110081651A CN 102204961 A CN102204961 A CN 102204961A
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- extract
- caulis
- folium fici
- fici tikouae
- digua
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Abstract
The invention discloses a digua fig stem extract and a new application thereof. The digua fig stem extract is prepared by the following method comprising the steps of: first, performing reflux extraction on the fresh whole plant of the digua fig stem by ethanol several times to obtain the extracting solution; second, concentrating the extracting solution obtained in the first step by pressure reduction to obtain the concentrated solution of the digua fig stem; third, extracting the concentrated solution of the digua fig stem obtained in the second step by ethyl acetate to obtain an ethyl acetate extract, then extracting by normal butanol to obtain a normal butanol extract; and finally, mixing the two extracts obtained in the third step, then drying by pressure reduction to obtain the end product, namely the digua fig stem extract. The digua fig stem extract has wide medicine sources, a simple extraction method, easiness of processing and a simple use method, and has obvious effects on treating hypopigmentation or depigmentation leucoderma.
Description
Technical field
The present invention relates to a kind of extract and new purposes thereof, relate in particular to a kind of Caulis et Folium fici Tikouae extract and new purposes thereof.
Background technology
Caulis et Folium fici Tikouae is a kind of common climing vine plant, the Caulis et Folium fici Tikouae aboundresources is widely distributed in the ground such as Sichuan, Guangxi, Guizhou, Hunan of China, is medical materials traditionally used in certain regions, its stem skill is cylindrical, diameter 4-6mm, normal with palpus shape adventitious root, surperficial brownish red is to burgundy, has vertical wrinkle, sprout has tangible ring-type stipule trace, and matter is hard slightly, and Section Central has marrow.The many fold of leaf, intact leaves is the shape of falling ovum ellipse, long 1.5-6cm, wide 1-4cm, the anxious point of tip, base portion is circular or near heart-shaped, edge tool serration, above celadon to bottle green, below celadon, the net veinclearing shows.Be used for chronic bronchitis, dysentery, infantile dyspepsia, rheumatalgia, innominate toxic swelling, impetigo, scabies etc., but the curing rheumatism numbness is controlled bones and muscles pain, the hemopoietic of invigorating blood circulation, the detumescence detoxification, diuresis is analgesic.Up to now, Caulis et Folium fici Tikouae does not appear in the newspapers as yet in the application aspect the treatment vitiligo.
Summary of the invention
Purpose of the present invention just is to provide a kind of Caulis et Folium fici Tikouae extract and the application in the treatment vitiligo thereof.
To achieve these goals, the technical solution used in the present invention is such: a kind of Caulis et Folium fici Tikouae extract, and this Caulis et Folium fici Tikouae extract is made by following method:
The first step utilizes ethanol with the bright product reflux, extract, of Caulis et Folium fici Tikouae herb for several times, obtains extracting solution;
In second step, the extracting solution concentrating under reduced pressure with the first step obtains obtains the Caulis et Folium fici Tikouae concentrated solution;
In the 3rd step, the Caulis et Folium fici Tikouae concentrated solution that second step was obtained extracts with ethyl acetate earlier, obtains acetic acid ethyl ester extract, and the reuse n-butyl alcohol extracts, and obtains n-butyl alcohol extract;
At last, mix two kinds of extracts that the 3rd step obtained, carry out drying under reduced pressure then, obtain end-product, i.e. the Caulis et Folium fici Tikouae extract.
Further, used concentration of ethanol is 70%, and the reflux, extract, number of times is 2 times.
The application of Caulis et Folium fici Tikouae extract in the treatment vitiligo.
Further, described vitiligo is hypopigmentation or takes off the property lost vitiligo.
Compared with prior art, the invention has the advantages that: the Caulis et Folium fici Tikouae method for preparing extractive is simple, and the medicine source is wide, cost is low, and is economical and practical, easily processing, be easy to the patient and accept, in treatment hypopigmentation or to take off the property lost vitiligo remarkably productive, for the treatment vitiligo provides a kind of new medicament sources.
Description of drawings
Fig. 1 is the process chart of Caulis et Folium fici Tikouae extract manufacture method of the present invention.
The specific embodiment
The invention will be further described below in conjunction with drawings and Examples.
Embodiment: referring to Fig. 1, a kind of Caulis et Folium fici Tikouae extract, this Caulis et Folium fici Tikouae extract is made by following method:
The first step utilizes ethanol with the bright product reflux, extract, of Caulis et Folium fici Tikouae herb for several times, obtains extracting solution;
In second step, the extracting solution concentrating under reduced pressure with the first step obtains obtains the Caulis et Folium fici Tikouae concentrated solution;
In the 3rd step, the Caulis et Folium fici Tikouae concentrated solution that second step was obtained extracts with ethyl acetate earlier, obtains acetic acid ethyl ester extract, and the reuse n-butyl alcohol extracts, and obtains n-butyl alcohol extract;
At last, mix two kinds of extracts that the 3rd step obtained, carry out drying under reduced pressure then, obtain end-product, i.e. the Caulis et Folium fici Tikouae extract.
As preferably, used concentration of ethanol is 70%, and the reflux, extract, number of times is 2 times.
The application of Caulis et Folium fici Tikouae extract in the treatment vitiligo, described vitiligo are hypopigmentation or take off the property lost vitiligo.
Caulis et Folium fici Tikouae extract for treating vitiligo principle: discover, the Caulis et Folium fici Tikouae extract is to tryrosinase activity ratio height, and vitiligo is a kind of more common depigmentation dermatoses, its main cause is that the tyrosinase activity reduction causes patient skin melanocyte biosynthesis block, tryrosinase is the biosynthetic main rate-limiting enzyme of skin melanocyte, its active and proportional relation of melanocyte synthetic quantity, by the Caulis et Folium fici Tikouae extract tryrosinase is activated, thereby the vigor of regulating tryrosinase is a may command melanocyte growing amount, affects the therapy for vitiligo effect.
Using method: the Caulis et Folium fici Tikouae extract is a kind of external liniment, during use it is spread upon vitiligo white macula number positional time, after half an hour, accepts sun exposure, and irradiation in initial several days 20 minutes is to half an hour, increases Exposure to Sunlight time to one hour afterwards gradually.Instant effect uses just can occur 2-3 the course of treatment taking a turn for the better usually, and wherein, be 10 days a course of treatment.
The Caulis et Folium fici Tikouae method for preparing extractive is simple, and the medicine source is wide, and cost is low, and is economical and practical, and easily processing is easy to the patient and accepts, in treatment hypopigmentation or to take off the property lost vitiligo remarkably productive, for the treatment vitiligo provides a kind of new medicament sources.
Claims (4)
1. Caulis et Folium fici Tikouae extract, it is characterized in that: this Caulis et Folium fici Tikouae extract is made by following method:
The first step utilizes ethanol with the bright product reflux, extract, of Caulis et Folium fici Tikouae herb for several times, obtains extracting solution;
In second step, the extracting solution concentrating under reduced pressure with the first step obtains obtains the Caulis et Folium fici Tikouae concentrated solution;
In the 3rd step, the Caulis et Folium fici Tikouae concentrated solution that second step was obtained extracts with ethyl acetate earlier, obtains acetic acid ethyl ester extract, and the reuse n-butyl alcohol extracts, and obtains n-butyl alcohol extract;
At last, mix two kinds of extracts that the 3rd step obtained, carry out drying under reduced pressure then, obtain end-product, i.e. the Caulis et Folium fici Tikouae extract.
2. Caulis et Folium fici Tikouae extract according to claim 1 is characterized in that: used concentration of ethanol is 70%, and the reflux, extract, number of times is 2 times.
3. the application of Caulis et Folium fici Tikouae extract as claimed in claim 1 or 2 in the treatment vitiligo.
4. Caulis et Folium fici Tikouae extract according to claim 3 is characterized in that: described vitiligo is hypopigmentation or takes off the property lost vitiligo.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100816514A CN102204961A (en) | 2011-04-01 | 2011-04-01 | Digua fig stem extract and new application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100816514A CN102204961A (en) | 2011-04-01 | 2011-04-01 | Digua fig stem extract and new application thereof |
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| CN102204961A true CN102204961A (en) | 2011-10-05 |
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| CN2011100816514A Pending CN102204961A (en) | 2011-04-01 | 2011-04-01 | Digua fig stem extract and new application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108553559A (en) * | 2018-06-22 | 2018-09-21 | 南昌糖友安健康科技有限公司 | A kind of vegetables and fruits extraction composition formula and preparation method for preventing type II diabetes |
-
2011
- 2011-04-01 CN CN2011100816514A patent/CN102204961A/en active Pending
Non-Patent Citations (5)
| Title |
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| 《六盘水师范高等专科学校学报》 20101031 杨朝钊，林长松 六盘水地区榕属植物资源的调查研究 11-15 1-4 , * |
| 《贵州农业科学》 20110131 王绪英, 向红 地果中黄酮化合物的提取工艺研究 202～204 1-4 , * |
| 关永霞，等: "苗药地瓜藤化学成分的研究", 《中草药》 * |
| 汤秀梅，等: "民族药地板藤的质量标准研究", 《云南中医中药杂志》 * |
| 熊友健，等: "呋喃香豆素类成分及其药理作用研究进展", 《中成药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108553559A (en) * | 2018-06-22 | 2018-09-21 | 南昌糖友安健康科技有限公司 | A kind of vegetables and fruits extraction composition formula and preparation method for preventing type II diabetes |
| CN108553559B (en) * | 2018-06-22 | 2021-03-23 | 南昌糖友安健康科技有限公司 | Formula and preparation method of vegetable and fruit extract for preventing and treating type II diabetes |
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Application publication date: 20111005 |