CN102203617A - 用于检测和诊断骨或软骨障碍的方法 - Google Patents

用于检测和诊断骨或软骨障碍的方法 Download PDF

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Publication number
CN102203617A
CN102203617A CN2009801419999A CN200980141999A CN102203617A CN 102203617 A CN102203617 A CN 102203617A CN 2009801419999 A CN2009801419999 A CN 2009801419999A CN 200980141999 A CN200980141999 A CN 200980141999A CN 102203617 A CN102203617 A CN 102203617A
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China
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antibody
seq
polypeptide
bone
peptide
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Pending
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CN2009801419999A
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English (en)
Chinese (zh)
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W·沃罗什楚克
G·哈瓦
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Biomarker Design Forschungs GmbH
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Biomarker Design Forschungs GmbH
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Publication of CN102203617A publication Critical patent/CN102203617A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2009801419999A 2008-10-22 2009-10-22 用于检测和诊断骨或软骨障碍的方法 Pending CN102203617A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10756408P 2008-10-22 2008-10-22
US61/107564 2008-10-22
PCT/EP2009/063909 WO2010046443A2 (en) 2008-10-22 2009-10-22 Methods for detection and diagnosis of a bone or cartilage disorder

Publications (1)

Publication Number Publication Date
CN102203617A true CN102203617A (zh) 2011-09-28

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ID=41403094

Family Applications (1)

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CN2009801419999A Pending CN102203617A (zh) 2008-10-22 2009-10-22 用于检测和诊断骨或软骨障碍的方法

Country Status (6)

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US (1) US20110189694A1 (https=)
EP (1) EP2359145A2 (https=)
JP (1) JP2012506551A (https=)
CN (1) CN102203617A (https=)
CA (1) CA2739159A1 (https=)
WO (1) WO2010046443A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106117357A (zh) * 2016-06-29 2016-11-16 烟台正海生物科技股份有限公司 Bmp‑2抗体及其在检测骨修复材料中bmp‑2蛋白含量中的应用
CN107383176A (zh) * 2017-05-10 2017-11-24 于学杰 用于对汉滩病毒和汉城病毒引起的肾综合征出血热分型的多肽
CN112449684A (zh) * 2018-09-12 2021-03-05 菲亚诺斯蒂克斯有限责任公司 用于诊断肝病的方法
CN118126974A (zh) * 2024-03-14 2024-06-04 江苏大学附属医院 骨关节炎标记物loxl1及其应用

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* Cited by examiner, † Cited by third party
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US9404932B2 (en) * 2007-11-05 2016-08-02 Nordic Bioscience A/S Pathology biomarker assay
GB201107922D0 (en) 2011-05-12 2011-06-22 Nordic Bioscience As Biochemical markers for CVD risk assessment
JP5873652B2 (ja) * 2011-05-31 2016-03-01 国立大学法人京都大学 軟骨疾患治療薬のスクリーニング方法および軟骨疾患治療用改変軟骨細胞
US20160091500A1 (en) * 2013-05-14 2016-03-31 Haglund Lisbet Chondroadherin fragments as indicators of intervertebral disc degeneration
JP6420074B2 (ja) 2013-06-27 2018-11-07 国立大学法人京都大学 プテロシン誘導体を含む軟骨欠損、軟骨変性、および／または軟骨菲薄疾患治療剤
PL3456339T3 (pl) * 2013-08-05 2022-03-21 Immatics Biotechnologies Gmbh Nowa immunoterapia przeciwko szeregu nowotworom, takim jak rak płuc, w tym nsclc
WO2016095046A1 (en) * 2014-12-19 2016-06-23 Val-Chum, Limited Partnership Dicam-specific antibodies and uses thereof
WO2016127035A1 (en) * 2015-02-05 2016-08-11 Duke University Methods of detecting osteoarthritis and predicting progression thereof
ES2983924T3 (es) 2015-03-27 2024-10-28 Immatics Biotechnologies Gmbh Péptidos novedosos y combinación de péptidos para usarse en inmunoterapia contra diferentes tumores
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
EP3223017A1 (en) 2016-03-25 2017-09-27 Université de Liège Osteomodulin and osteomodulin fragments as biomarkers for osteoarthritis and use thereof
US10646540B2 (en) * 2016-11-18 2020-05-12 City Of Hope Peptide inhibitors of twist
WO2021243136A2 (en) * 2020-05-29 2021-12-02 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Methods and compositions for treating, preventing the onset and/or slowing progression of osteoarthritis
CN118414161A (zh) * 2021-12-30 2024-07-30 哈普赛安思有限公司 包括hapln1的用于预防或治疗干眼症的组合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857456A (en) * 1985-04-30 1989-08-15 The Regents Of The University Of California Assay of Bone morphogenetic protein (BMP) and anti-BMP antibody for the diagnosis of bone disorders
WO2007045661A1 (en) * 2005-10-20 2007-04-26 Nordic Bioscience Diagnostics A/S Detection or quantification of aggrecan and its fragments
EP1780276A1 (en) * 2004-08-04 2007-05-02 Riken Bone/joint disease sensitivity gene and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057795A2 (en) * 2001-01-19 2002-07-25 Cambridge Scientific, Inc. Methods of diagnosis and treatment of osteoporosis
AU2003296953A1 (en) * 2002-12-12 2004-07-09 Strategic Diagnostics Inc. Compositions and methods for detecting animal by product in feed
US8012950B2 (en) * 2003-08-29 2011-09-06 Wisconsin Alumni Research Foundation Method to diagnose and treat degenerative joint disease
GB0510511D0 (en) * 2005-05-23 2005-06-29 St Georges Entpr Ltd Diagnosis of tuberculosis
WO2008046511A1 (en) * 2006-10-16 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Crtac as a biomarker, therapeutic and diagnostic target
AU2008246125B2 (en) * 2007-04-26 2013-01-24 Genera Istrazivanja D.O.O. Blood biomarkers for bone fracture and cartilage injury

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857456A (en) * 1985-04-30 1989-08-15 The Regents Of The University Of California Assay of Bone morphogenetic protein (BMP) and anti-BMP antibody for the diagnosis of bone disorders
EP1780276A1 (en) * 2004-08-04 2007-05-02 Riken Bone/joint disease sensitivity gene and use thereof
WO2007045661A1 (en) * 2005-10-20 2007-04-26 Nordic Bioscience Diagnostics A/S Detection or quantification of aggrecan and its fragments

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106117357A (zh) * 2016-06-29 2016-11-16 烟台正海生物科技股份有限公司 Bmp‑2抗体及其在检测骨修复材料中bmp‑2蛋白含量中的应用
CN106117357B (zh) * 2016-06-29 2019-08-30 烟台正海生物科技股份有限公司 Bmp-2抗体及其在检测骨修复材料中bmp-2蛋白含量中的应用
CN107383176A (zh) * 2017-05-10 2017-11-24 于学杰 用于对汉滩病毒和汉城病毒引起的肾综合征出血热分型的多肽
CN112449684A (zh) * 2018-09-12 2021-03-05 菲亚诺斯蒂克斯有限责任公司 用于诊断肝病的方法
CN118126974A (zh) * 2024-03-14 2024-06-04 江苏大学附属医院 骨关节炎标记物loxl1及其应用

Also Published As

Publication number Publication date
CA2739159A1 (en) 2010-04-29
EP2359145A2 (en) 2011-08-24
JP2012506551A (ja) 2012-03-15
WO2010046443A3 (en) 2010-08-12
WO2010046443A2 (en) 2010-04-29
US20110189694A1 (en) 2011-08-04

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Application publication date: 20110928